{"id":"https://openalex.org/W2011673302","doi":"https://doi.org/10.1118/1.3469255","title":"TU-D-BRB-06: Localizing Intracavitary Brachytherapy Applicators from Conebeam CT X-Ray Projections Via a Novel Iterative Forward Projection Matching (IFPM) Algorithm","display_name":"TU-D-BRB-06: Localizing Intracavitary Brachytherapy Applicators from Conebeam CT X-Ray Projections Via a Novel Iterative Forward Projection Matching (IFPM) Algorithm","publication_year":2010,"publication_date":"2010-06-01","ids":{"openalex":"https://openalex.org/W2011673302","doi":"https://doi.org/10.1118/1.3469255","mag":"2011673302"},"language":"en","primary_location":{"id":"doi:10.1118/1.3469255","doi":"https://doi.org/10.1118/1.3469255","is_oa":false,"landing_page_url":"https://doi.org/10.1118/1.3469255","pdf_url":null,"source":{"id":"https://openalex.org/S95522064","display_name":"Medical Physics","issn_l":"0094-2405","issn":["0094-2405","1522-8541","2473-4209"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Physics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078505756","display_name":"Damodar Pokhrel","orcid":"https://orcid.org/0000-0003-2694-1047","observed_orcids":["https://orcid.org/0000-0003-2694-1047"]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D Pokhrel","raw_affiliation_strings":["Virginia Commonwealth University, Richmond, VA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Virginia Commonwealth University, Richmond, VA","institution_ids":["https://openalex.org/I184840846"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044115824","display_name":"Martin J. Murphy","orcid":"https://orcid.org/0000-0003-1108-3967","observed_orcids":["https://orcid.org/0000-0003-1108-3967"]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M Murphy","raw_affiliation_strings":["Virginia Commonwealth University, Richmond, VA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Virginia Commonwealth University, Richmond, VA","institution_ids":["https://openalex.org/I184840846"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067795974","display_name":"Dorin A. Todor","orcid":"https://orcid.org/0000-0001-6771-6685","observed_orcids":["https://orcid.org/0000-0001-6771-6685"]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D Todor","raw_affiliation_strings":["Virginia Commonwealth University, Richmond, VA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Virginia Commonwealth University, Richmond, VA","institution_ids":["https://openalex.org/I184840846"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103053731","display_name":"Elisabeth Weiss","orcid":"https://orcid.org/0000-0003-1519-3768","observed_orcids":["https://orcid.org/0000-0003-1519-3768"]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E Weiss","raw_affiliation_strings":["Virginia Commonwealth University, Richmond, VA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Virginia Commonwealth University, Richmond, VA","institution_ids":["https://openalex.org/I184840846"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111646145","display_name":"Jeffrey Williamson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J Williamson","raw_affiliation_strings":["Virginia Commonwealth University, Richmond, VA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Virginia Commonwealth University, Richmond, VA","institution_ids":["https://openalex.org/I184840846"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I184840846"],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.1514858,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"37","issue":"6Part27","first_page":"3392","last_page":"3392"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.5249000191688538,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.5249000191688538,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.41670000553131104,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10844","display_name":"Radiation Dose and Imaging","score":0.014000000432133675,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intracavitary-brachytherapy","display_name":"intracavitary brachytherapy","score":0.9829999804496765},{"id":"https://openalex.org/keywords/cone-beam-computed-tomography","display_name":"cone-beam computed tomography","score":0.7979999780654907},{"id":"https://openalex.org/keywords/tandem-applicator","display_name":"tandem applicator","score":0.7549999952316284},{"id":"https://openalex.org/keywords/x-ray-projections","display_name":"X-ray projections","score":0.5740000009536743},{"id":"https://openalex.org/keywords/dose-distribution","display_name":"dose distribution","score":0.5889999866485596}],"concepts":[{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.6256259679794312},{"id":"https://openalex.org/C57493831","wikidata":"https://www.wikidata.org/wiki/Q3134666","display_name":"Projection (relational algebra)","level":2,"score":0.5897964239120483},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5879368782043457},{"id":"https://openalex.org/C104293457","wikidata":"https://www.wikidata.org/wiki/Q28324852","display_name":"Imaging phantom","level":2,"score":0.5236542224884033},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.505772590637207},{"id":"https://openalex.org/C166704113","wikidata":"https://www.wikidata.org/wiki/Q861092","display_name":"Image registration","level":3,"score":0.5015163421630859},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.5005860328674316},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.492969274520874},{"id":"https://openalex.org/C2777416452","wikidata":"https://www.wikidata.org/wiki/Q896687","display_name":"Brachytherapy","level":3,"score":0.4867408275604248},{"id":"https://openalex.org/C146160929","wikidata":"https://www.wikidata.org/wiki/Q751290","display_name":"Euler angles","level":2,"score":0.43243059515953064},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.42903149127960205},{"id":"https://openalex.org/C60056205","wikidata":"https://www.wikidata.org/wiki/Q691914","display_name":"Opacity","level":2,"score":0.4173974096775055},{"id":"https://openalex.org/C165064840","wikidata":"https://www.wikidata.org/wiki/Q1321061","display_name":"Matching (statistics)","level":2,"score":0.41676050424575806},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.36926156282424927},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.329393208026886},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2677893042564392},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.2544102072715759},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.24980702996253967},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.22350528836250305},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.11087971925735474},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1118/1.3469255","doi":"https://doi.org/10.1118/1.3469255","is_oa":false,"landing_page_url":"https://doi.org/10.1118/1.3469255","pdf_url":null,"source":{"id":"https://openalex.org/S95522064","display_name":"Medical Physics","issn_l":"0094-2405","issn":["0094-2405","1522-8541","2473-4209"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Physics","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2045893304","https://openalex.org/W1662811875","https://openalex.org/W2083617067","https://openalex.org/W43600105","https://openalex.org/W2063107330","https://openalex.org/W2057154130","https://openalex.org/W2082244293","https://openalex.org/W1991399225","https://openalex.org/W2170329882","https://openalex.org/W2058809568"],"abstract_inverted_index":{"Purpose:":[0],"To":[1,137],"present":[2],"a":[3,23,85,92,218],"novel":[4],"method":[5,224],"for":[6,166,211,275],"reconstructing":[7],"the":[8,41,46,50,63,69,78,98,141,146,155,159,171,174,201,205,243,248,250,259,276],"3D":[9,143],"pose":[10,43,70,144],"(positions":[11,72],"&":[12],"orientations)":[13],"of":[14,17,26,32,62,87,97,103,117,145,229,252],"radio-opaque":[15,227],"objects":[16],"known":[18,110],"but":[19],"arbitrary":[20,230],"shape":[21,231],"from":[22,91,123,232],"small":[24],"set":[25],"2D":[27],"x-ray":[28,233],"projections,":[29],"in":[30,258,282],"support":[31],"intraoperative":[33],"brachytherapy":[34],"planning.":[35],"Methods":[36],"and":[37,52,73,105,152,158,176,182,194,221,247,265,270,278],"materials:":[38],"IFPM":[39,66,139],"finds":[40],"object":[42,55],"by":[44,286],"minimizing":[45],"sum-of-squared-intensity-differences":[47],"(SSD)":[48],"between":[49],"computed":[51,104,165],"experimentally-acquired":[53],"auto-segmented":[54],"projections.":[56,234],"Starting":[57],"with":[58,109,154,189,268],"an":[59,118],"initial":[60],"estimate":[61],"applicator":[64,82,147,244],"pose,":[65],"iteratively":[67],"refines":[68],"parameters":[71],"3":[74],"Euler":[75],"angles)":[76],"until":[77],"SSD":[79],"converges.":[80],"The":[81],"model":[83,96,148],"is":[84,239],"mesh":[86],"discrete":[88],"points":[89],"derived":[90],"complex":[93],"combinatorial":[94],"geometric":[95],"actual":[99],"applicator.":[100],"Three":[101],"pairs":[102],"measured":[106,156,202],"projection":[107],"images,":[108,204],"imaging":[111],"geometry,":[112],"are":[113],"used.":[114],"Projection":[115],"images":[116,157],"intrauterine":[119],"tandem":[120,175,203,269],"were":[121,187],"acquired":[122],"Acuity":[124],"digital-simulator.":[125],"Image":[126],"pre-processing":[127],"step":[128],"was":[129,149,164,207],"performed":[130,274],"to":[131,225],"create":[132],"blurred":[133],"binary":[134],"applicator-only":[135],"images.":[136],"quantify":[138],"accuracy,":[140],"reconstructed":[142],"forward":[150],"projected":[151],"overlaid":[153],"dice":[160],"similarity":[161],"coefficient":[162],"(DSC)":[163],"each":[167,212],"image-pair.":[168,213],"Results:":[169],"In":[170],"numerical":[172],"simulations,":[173],"colpostats":[177,271],"positions":[178],"(x,":[179],"y,":[180],"z)":[181],"orientations":[183],"(\u03b1,":[184],"\u03b2,":[185],"\u03b3)":[186],"estimated":[188],"(0.28,":[190],"0.3,":[191],"0.37)":[192],"mm":[193],"(0.9,":[195],"0.8,":[196],"1.0)\u00b0":[197],"accuracies,":[198],"respectively.":[199],"For":[200],"DSC":[206],"better":[208],"than":[209],"0.88":[210],"Discussion:":[214],"We":[215],"have":[216],"developed":[217],"new,":[219],"accurate,":[220],"completely":[222],"automatic":[223],"localize":[226],"applicators":[228],"Also,":[235],"no":[236],"lateral":[237],"film":[238],"required.":[240],"By":[241],"localizing":[242],"internal":[245],"structure":[246],"sources,":[249],"effect":[251],"intra/inter-applicator":[253],"attenuation":[254],"can":[255],"be":[256,273],"included":[257],"resultant":[260],"dose":[261],"distribution.":[262],"Further":[263],"development":[264],"validation":[266],"tests":[267],"will":[272],"accurate":[277],"robust":[279],"applicator/sources":[280],"localization":[281],"ICB":[283],"patients.":[284],"Supported":[285],"Varian":[287],"Medical":[288],"Systems":[289]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}