{"id":"https://openalex.org/W2011579418","doi":"https://doi.org/10.1016/s0015-0282(00)01583-1","title":"Effects of simulated microgravity on mammalian fertilization and preimplantation embryonic development in vitro","display_name":"Effects of simulated microgravity on mammalian fertilization and preimplantation embryonic development in vitro","publication_year":2000,"publication_date":"2000-12-01","ids":{"openalex":"https://openalex.org/W2011579418","doi":"https://doi.org/10.1016/s0015-0282(00)01583-1","mag":"2011579418","pmid":"https://pubmed.ncbi.nlm.nih.gov/11119741"},"language":"en","primary_location":{"id":"doi:10.1016/s0015-0282(00)01583-1","doi":"https://doi.org/10.1016/s0015-0282(00)01583-1","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0015-0282(00)01583-1","pdf_url":"http://www.fertstert.org/article/S0015028200015831/pdf","source":{"id":"https://openalex.org/S45445671","display_name":"Fertility and Sterility","issn_l":"0015-0282","issn":["0015-0282","1556-5653"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fertility and Sterility","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.fertstert.org/article/S0015028200015831/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100813933","display_name":"Yoshiyuki Kojima","orcid":"https://orcid.org/0000-0001-8000-0868","observed_orcids":["https://orcid.org/0000-0001-8000-0868"]},"institutions":[{"id":"https://openalex.org/I33858575","display_name":"Nagoya City University","ror":"https://ror.org/04wn7wc95","country_code":"JP","type":"education","lineage":["https://openalex.org/I33858575"]},{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Yoshiyuki Kojima","raw_affiliation_strings":["Department of Urology, Nagoya City University Medical School, Nagoya, Japan. yoshi.kojima@nifty.ne.jp","Department of Urology Nagoya City University Medical School Nagoya Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Nagoya City University Medical School, Nagoya, Japan. yoshi.kojima@nifty.ne.jp","institution_ids":["https://openalex.org/I33858575"]},{"raw_affiliation_string":"Department of Urology Nagoya City University Medical School Nagoya Japan","institution_ids":["https://openalex.org/I33858575","https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102783002","display_name":"Shoichi Sasaki","orcid":"https://orcid.org/0000-0002-5796-6039","observed_orcids":["https://orcid.org/0000-0002-5796-6039"]},"institutions":[{"id":"https://openalex.org/I33858575","display_name":"Nagoya City University","ror":"https://ror.org/04wn7wc95","country_code":"JP","type":"education","lineage":["https://openalex.org/I33858575"]},{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shoichi Sasaki","raw_affiliation_strings":["Department of Urology, Nagoya City University Medical School, Nagoya, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Nagoya City University Medical School, Nagoya, Japan","institution_ids":["https://openalex.org/I33858575","https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060067726","display_name":"Yasue Kubota","orcid":"https://orcid.org/0000-0003-3944-0276","observed_orcids":["https://orcid.org/0000-0003-3944-0276"]},"institutions":[{"id":"https://openalex.org/I33858575","display_name":"Nagoya City University","ror":"https://ror.org/04wn7wc95","country_code":"JP","type":"education","lineage":["https://openalex.org/I33858575"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasue Kubota","raw_affiliation_strings":["Department of Urology , Nagoya City University Medical School , Nagoya , Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology , Nagoya City University Medical School , Nagoya , Japan","institution_ids":["https://openalex.org/I33858575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014194918","display_name":"Takahito Ikeuchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33858575","display_name":"Nagoya City University","ror":"https://ror.org/04wn7wc95","country_code":"JP","type":"education","lineage":["https://openalex.org/I33858575"]},{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takahito Ikeuchi","raw_affiliation_strings":["Department of Urology, Nagoya City University Medical School, Nagoya, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Nagoya City University Medical School, Nagoya, Japan","institution_ids":["https://openalex.org/I33858575","https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002931149","display_name":"Yutaro Hayashi","orcid":"https://orcid.org/0000-0001-7309-5854","observed_orcids":["https://orcid.org/0000-0001-7309-5854"]},"institutions":[{"id":"https://openalex.org/I33858575","display_name":"Nagoya City University","ror":"https://ror.org/04wn7wc95","country_code":"JP","type":"education","lineage":["https://openalex.org/I33858575"]},{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yutaro Hayashi","raw_affiliation_strings":["Department of Urology, Nagoya City University Medical School, Nagoya, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Nagoya City University Medical School, Nagoya, Japan","institution_ids":["https://openalex.org/I33858575","https://openalex.org/I60134161"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103457945","display_name":"Kenjiro Kohri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33858575","display_name":"Nagoya City University","ror":"https://ror.org/04wn7wc95","country_code":"JP","type":"education","lineage":["https://openalex.org/I33858575"]},{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kenjiro Kohri","raw_affiliation_strings":["Department of Urology, Nagoya City University Medical School, Nagoya, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Nagoya City University Medical School, Nagoya, Japan","institution_ids":["https://openalex.org/I33858575","https://openalex.org/I60134161"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100813933"],"corresponding_institution_ids":["https://openalex.org/I33858575","https://openalex.org/I60134161"],"apc_list":{"value":4220,"currency":"USD","value_usd":4220},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":48,"citation_normalized_percentile":{"value":0.1400831,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"74","issue":"6","first_page":"1142","last_page":"1147"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.019200000911951065,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/simulated-microgravity","display_name":"simulated microgravity","score":0.9940000176429749},{"id":"https://openalex.org/keywords/clinostat-rotation","display_name":"clinostat rotation","score":0.7409999966621399},{"id":"https://openalex.org/keywords/in-vitro-fertilization","display_name":"in vitro fertilization","score":0.8349999785423279},{"id":"https://openalex.org/keywords/preimplantation-embryo-development","display_name":"preimplantation embryo development","score":0.8930000066757202},{"id":"https://openalex.org/keywords/blastocyst-development","display_name":"blastocyst development","score":0.7570000290870667},{"id":"https://openalex.org/keywords/morula-stage","display_name":"morula stage","score":0.6790000200271606},{"id":"https://openalex.org/keywords/embryonic-lethality","display_name":"embryonic lethality","score":0.8240000009536743},{"id":"https://openalex.org/keywords/mouse-embryo","display_name":"mouse embryo","score":0.7720000147819519}],"concepts":[{"id":"https://openalex.org/C2777393558","wikidata":"https://www.wikidata.org/wiki/Q2979318","display_name":"Clinostat","level":2,"score":0.9764140248298645},{"id":"https://openalex.org/C2778177303","wikidata":"https://www.wikidata.org/wiki/Q227717","display_name":"Blastocyst","level":4,"score":0.8701281547546387},{"id":"https://openalex.org/C88972607","wikidata":"https://www.wikidata.org/wiki/Q2666904","display_name":"Human fertilization","level":2,"score":0.8163738250732422},{"id":"https://openalex.org/C512716672","wikidata":"https://www.wikidata.org/wiki/Q200117","display_name":"In vitro fertilisation","level":3,"score":0.7149320840835571},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.6908391714096069},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.6510294675827026},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.6461063623428345},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.6414907574653625},{"id":"https://openalex.org/C159879943","wikidata":"https://www.wikidata.org/wiki/Q14890574","display_name":"Fertilisation","level":5,"score":0.5655900239944458},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.541326642036438},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5006463527679443},{"id":"https://openalex.org/C28748434","wikidata":"https://www.wikidata.org/wiki/Q170145","display_name":"Zygote","level":4,"score":0.48746156692504883},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.37662985920906067},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.36954858899116516},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1735803484916687},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1451796293258667},{"id":"https://openalex.org/C2994278967","wikidata":"https://www.wikidata.org/wiki/Q7314318","display_name":"Reproductive technology","level":4,"score":0.07895424962043762},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001755","descriptor_name":"Blastocyst","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004624","descriptor_name":"Embryo Transfer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005306","descriptor_name":"Fertilization","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008811","descriptor_name":"Mice, Inbred DBA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012399","descriptor_name":"Rotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018474","descriptor_name":"Weightlessness Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0015-0282(00)01583-1","doi":"https://doi.org/10.1016/s0015-0282(00)01583-1","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0015-0282(00)01583-1","pdf_url":"http://www.fertstert.org/article/S0015028200015831/pdf","source":{"id":"https://openalex.org/S45445671","display_name":"Fertility and Sterility","issn_l":"0015-0282","issn":["0015-0282","1556-5653"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fertility and Sterility","raw_type":"journal-article"},{"id":"pmid:11119741","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11119741","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fertility and sterility","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/s0015-0282(00)01583-1","doi":"https://doi.org/10.1016/s0015-0282(00)01583-1","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0015-0282(00)01583-1","pdf_url":"http://www.fertstert.org/article/S0015028200015831/pdf","source":{"id":"https://openalex.org/S45445671","display_name":"Fertility and Sterility","issn_l":"0015-0282","issn":["0015-0282","1556-5653"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fertility and Sterility","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2011579418.pdf","grobid_xml":"https://content.openalex.org/works/W2011579418.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W63303536","https://openalex.org/W93928392","https://openalex.org/W192318080","https://openalex.org/W586011909","https://openalex.org/W765107045","https://openalex.org/W795840434","https://openalex.org/W798493079","https://openalex.org/W1484163259","https://openalex.org/W1485147594","https://openalex.org/W1509835122","https://openalex.org/W1579614835","https://openalex.org/W1946702933","https://openalex.org/W1977553332","https://openalex.org/W1983801204","https://openalex.org/W1999487669","https://openalex.org/W2025825454","https://openalex.org/W2042752159","https://openalex.org/W2059193195","https://openalex.org/W2069169998","https://openalex.org/W2072242201","https://openalex.org/W2078826636","https://openalex.org/W2136106837","https://openalex.org/W2398644683","https://openalex.org/W2400035277","https://openalex.org/W2408329771","https://openalex.org/W2420772176","https://openalex.org/W2474807629","https://openalex.org/W2484394945","https://openalex.org/W2586781288","https://openalex.org/W2738128030"],"related_works":["https://openalex.org/W2091760438","https://openalex.org/W2370027042","https://openalex.org/W7054153953","https://openalex.org/W7099338527","https://openalex.org/W832307345","https://openalex.org/W765107045","https://openalex.org/W7140434102","https://openalex.org/W318999496","https://openalex.org/W4400847230","https://openalex.org/W795840434"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}