{"id":"https://openalex.org/W2011560432","doi":"https://doi.org/10.1016/j.bbrc.2009.11.057","title":"Protein arginine methyltransferase 1 regulates herpes simplex virus replication through ICP27 RGG-box methylation","display_name":"Protein arginine methyltransferase 1 regulates herpes simplex virus replication through ICP27 RGG-box methylation","publication_year":2009,"publication_date":"2009-11-13","ids":{"openalex":"https://openalex.org/W2011560432","doi":"https://doi.org/10.1016/j.bbrc.2009.11.057","mag":"2011560432","pmid":"https://pubmed.ncbi.nlm.nih.gov/19913501"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbrc.2009.11.057","doi":"https://doi.org/10.1016/j.bbrc.2009.11.057","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bbrc.2009.11.057","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090353903","display_name":"Jungeun Yu","orcid":"https://orcid.org/0000-0002-4036-4867","observed_orcids":["https://orcid.org/0000-0002-4036-4867"]},"institutions":[{"id":"https://openalex.org/I196345858","display_name":"Chungnam National University","ror":"https://ror.org/0227as991","country_code":"KR","type":"education","lineage":["https://openalex.org/I196345858"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jungeun Yu","raw_affiliation_strings":["Department of Microbiology, Chungnam National University, Yuseong-gu, Daejon 305-764, Republic of Korea","BK21 Bio Brain Center, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","Department of Microbiology, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Chungnam National University, Yuseong-gu, Daejon 305-764, Republic of Korea","institution_ids":["https://openalex.org/I196345858"]},{"raw_affiliation_string":"BK21 Bio Brain Center, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","institution_ids":["https://openalex.org/I196345858"]},{"raw_affiliation_string":"Department of Microbiology, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","institution_ids":["https://openalex.org/I196345858"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076488336","display_name":"Bongjin Shin","orcid":"https://orcid.org/0000-0002-3763-2613","observed_orcids":["https://orcid.org/0000-0002-3763-2613"]},"institutions":[{"id":"https://openalex.org/I196345858","display_name":"Chungnam National University","ror":"https://ror.org/0227as991","country_code":"KR","type":"education","lineage":["https://openalex.org/I196345858"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Bongjin Shin","raw_affiliation_strings":["BK21 Bio Brain Center, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","Department of Microbiology, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BK21 Bio Brain Center, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","institution_ids":["https://openalex.org/I196345858"]},{"raw_affiliation_string":"Department of Microbiology, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","institution_ids":["https://openalex.org/I196345858"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024525296","display_name":"Eui\u2010Soon Park","orcid":"https://orcid.org/0000-0002-1375-8027","observed_orcids":["https://orcid.org/0000-0002-1375-8027"]},"institutions":[{"id":"https://openalex.org/I196345858","display_name":"Chungnam National University","ror":"https://ror.org/0227as991","country_code":"KR","type":"education","lineage":["https://openalex.org/I196345858"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Eui-Soon Park","raw_affiliation_strings":["BK21 Bio Brain Center, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","Department of Microbiology, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BK21 Bio Brain Center, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","institution_ids":["https://openalex.org/I196345858"]},{"raw_affiliation_string":"Department of Microbiology, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","institution_ids":["https://openalex.org/I196345858"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078178914","display_name":"Sujeong Yang","orcid":"https://orcid.org/0000-0002-9402-7460","observed_orcids":["https://orcid.org/0000-0002-9402-7460"]},"institutions":[{"id":"https://openalex.org/I196345858","display_name":"Chungnam National University","ror":"https://ror.org/0227as991","country_code":"KR","type":"education","lineage":["https://openalex.org/I196345858"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sujeong Yang","raw_affiliation_strings":["BK21 Bio Brain Center, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","Department of Microbiology, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BK21 Bio Brain Center, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","institution_ids":["https://openalex.org/I196345858"]},{"raw_affiliation_string":"Department of Microbiology, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","institution_ids":["https://openalex.org/I196345858"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081478831","display_name":"Seunga Choi","orcid":"https://orcid.org/0000-0002-6688-8239","observed_orcids":["https://orcid.org/0000-0002-6688-8239"]},"institutions":[{"id":"https://openalex.org/I196345858","display_name":"Chungnam National University","ror":"https://ror.org/0227as991","country_code":"KR","type":"education","lineage":["https://openalex.org/I196345858"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Seunga Choi","raw_affiliation_strings":["BK21 Bio Brain Center, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","Department of Microbiology, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BK21 Bio Brain Center, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","institution_ids":["https://openalex.org/I196345858"]},{"raw_affiliation_string":"Department of Microbiology, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","institution_ids":["https://openalex.org/I196345858"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015626811","display_name":"Mi-Sun Kang","orcid":"https://orcid.org/0000-0003-3629-2589","observed_orcids":["https://orcid.org/0000-0003-3629-2589"]},"institutions":[{"id":"https://openalex.org/I196345858","display_name":"Chungnam National University","ror":"https://ror.org/0227as991","country_code":"KR","type":"education","lineage":["https://openalex.org/I196345858"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Misun Kang","raw_affiliation_strings":["Department of Microbiology, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","institution_ids":["https://openalex.org/I196345858"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061765328","display_name":"Jaerang Rho","orcid":"https://orcid.org/0000-0002-0019-4939","observed_orcids":["https://orcid.org/0000-0002-0019-4939"]},"institutions":[{"id":"https://openalex.org/I196345858","display_name":"Chungnam National University","ror":"https://ror.org/0227as991","country_code":"KR","type":"education","lineage":["https://openalex.org/I196345858"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Jaerang Rho","raw_affiliation_strings":["BK21 Bio Brain Center, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","Department of Microbiology, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","GRAST, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BK21 Bio Brain Center, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","institution_ids":["https://openalex.org/I196345858"]},{"raw_affiliation_string":"Department of Microbiology, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","institution_ids":["https://openalex.org/I196345858"]},{"raw_affiliation_string":"GRAST, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejon 305-764, Republic of Korea","institution_ids":["https://openalex.org/I196345858"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5061765328"],"corresponding_institution_ids":["https://openalex.org/I196345858"],"apc_list":{"value":3110,"currency":"USD","value_usd":3110},"apc_paid":null,"fwci":1.0726,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.72494727,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"391","issue":"1","first_page":"322","last_page":"328"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13157","display_name":"Cancer-related gene regulation","score":0.9369999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13157","display_name":"Cancer-related gene regulation","score":0.9369999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.05400000140070915,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prmt1","display_name":"PRMT1","score":0.9179999828338623},{"id":"https://openalex.org/keywords/protein-arginine-methylation","display_name":"arginine methylation","score":0.8989999890327454},{"id":"https://openalex.org/keywords/icp27","display_name":"ICP27","score":0.8989999890327454},{"id":"https://openalex.org/keywords/rgg-box","display_name":"RGG box","score":0.7839999794960022},{"id":"https://openalex.org/keywords/herpes-simplex-virus-type-1","display_name":"herpes simplex virus type 1","score":0.9710000157356262},{"id":"https://openalex.org/keywords/viral-replication","display_name":"viral replication","score":0.9819999933242798},{"id":"https://openalex.org/keywords/viral-gene-expression","display_name":"viral gene expression","score":0.6309999823570251},{"id":"https://openalex.org/keywords/rna-binding-activity","display_name":"RNA-binding activity","score":0.9319999814033508},{"id":"https://openalex.org/keywords/prmt-inhibitors","display_name":"PRMT inhibitors","score":0.9020000100135803}],"concepts":[{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.826339840888977},{"id":"https://openalex.org/C2777468819","wikidata":"https://www.wikidata.org/wiki/Q173670","display_name":"Arginine","level":3,"score":0.7276092767715454},{"id":"https://openalex.org/C111819275","wikidata":"https://www.wikidata.org/wiki/Q18035368","display_name":"Protein arginine methyltransferase 5","level":5,"score":0.6314569115638733},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6278772354125977},{"id":"https://openalex.org/C2778178838","wikidata":"https://www.wikidata.org/wiki/Q14876922","display_name":"Protein methylation","level":5,"score":0.5722326040267944},{"id":"https://openalex.org/C2781196997","wikidata":"https://www.wikidata.org/wiki/Q655331","display_name":"Herpes simplex virus","level":3,"score":0.46062201261520386},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.44534674286842346},{"id":"https://openalex.org/C91965660","wikidata":"https://www.wikidata.org/wiki/Q415875","display_name":"Methyltransferase","level":4,"score":0.4325523376464844},{"id":"https://openalex.org/C140704245","wikidata":"https://www.wikidata.org/wiki/Q3933202","display_name":"Viral replication","level":3,"score":0.4307510554790497},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.2721807360649109},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.23339343070983887},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.19056791067123413},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17616775631904602},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.11975321173667908}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001120","descriptor_name":"Arginine","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001120","descriptor_name":"Arginine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D004791","descriptor_name":"Enzyme Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008745","descriptor_name":"Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011484","descriptor_name":"Protein-Arginine N-Methyltransferases","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D011484","descriptor_name":"Protein-Arginine N-Methyltransferases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017874","descriptor_name":"Immediate-Early Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017874","descriptor_name":"Immediate-Early Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018139","descriptor_name":"Simplexvirus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018139","descriptor_name":"Simplexvirus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D019943","descriptor_name":"Amino Acid Substitution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.bbrc.2009.11.057","doi":"https://doi.org/10.1016/j.bbrc.2009.11.057","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bbrc.2009.11.057","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},{"id":"pmid:19913501","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19913501","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and biophysical research communications","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.428600013256073,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1577117579","https://openalex.org/W1963559299","https://openalex.org/W1993519463","https://openalex.org/W2014481446","https://openalex.org/W2025726628","https://openalex.org/W2030107543","https://openalex.org/W2043623361","https://openalex.org/W2057379290","https://openalex.org/W2062756359","https://openalex.org/W2066020764","https://openalex.org/W2069512527","https://openalex.org/W2076142854","https://openalex.org/W2086992870","https://openalex.org/W2092809155","https://openalex.org/W2098784640","https://openalex.org/W2104482615","https://openalex.org/W2121672427","https://openalex.org/W2131605493","https://openalex.org/W2141734908","https://openalex.org/W2141815936","https://openalex.org/W2153117746","https://openalex.org/W2155854380","https://openalex.org/W2156211472","https://openalex.org/W2157204551","https://openalex.org/W2161592205","https://openalex.org/W6654089270"],"related_works":["https://openalex.org/W7096462010","https://openalex.org/W2131605493","https://openalex.org/W2114473576","https://openalex.org/W2104482615","https://openalex.org/W2141815936","https://openalex.org/W4388104877","https://openalex.org/W7096284427","https://openalex.org/W7096327177","https://openalex.org/W2109263677","https://openalex.org/W7096835669"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}