{"id":"https://openalex.org/W2011484198","doi":"https://doi.org/10.1016/0020-7292(87)90105-6","title":"Effect on birth weight of erythromycin treatment of pregnant women","display_name":"Effect on birth weight of erythromycin treatment of pregnant women","publication_year":1987,"publication_date":"1987-12-01","ids":{"openalex":"https://openalex.org/W2011484198","doi":"https://doi.org/10.1016/0020-7292(87)90105-6","mag":"2011484198","pmid":"https://pubmed.ncbi.nlm.nih.gov/3543767"},"language":"en","primary_location":{"id":"doi:10.1016/0020-7292(87)90105-6","doi":"https://doi.org/10.1016/0020-7292(87)90105-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0020-7292(87)90105-6","pdf_url":null,"source":{"id":"https://openalex.org/S4210216427","display_name":"International Journal of Gynecology & Obstetrics","issn_l":"0020-6695","issn":["0020-6695","0020-7292","1879-3479"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Gynecology & Obstetrics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112013997","display_name":"William M. McCormack","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"WM McCormack","raw_affiliation_strings":["Boston University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089191285","display_name":"BERNARD A. ROSNER","orcid":"https://orcid.org/0000-0001-6907-0056","observed_orcids":["https://orcid.org/0000-0001-6907-0056"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B Rosner","raw_affiliation_strings":["Boston University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109122772","display_name":"Y H Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Y\u2010H Lee","raw_affiliation_strings":["Boston University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University","institution_ids":["https://openalex.org/I111088046"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I111088046"],"apc_list":{"value":4480,"currency":"USD","value_usd":4480},"apc_paid":null,"fwci":4.6205,"has_fulltext":false,"cited_by_count":94,"citation_normalized_percentile":{"value":0.94491047,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"25","issue":"6","first_page":"491","last_page":"491"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11290","display_name":"Preterm Birth and Chorioamnionitis","score":0.5170999765396118,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11290","display_name":"Preterm Birth and Chorioamnionitis","score":0.5170999765396118,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.20800000429153442,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.15559999644756317,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/erythromycin","display_name":"erythromycin","score":0.9819999933242798},{"id":"https://openalex.org/keywords/birth-weight","display_name":"birth weight","score":0.8320000171661377},{"id":"https://openalex.org/keywords/low-birth-weight","display_name":"low birth weight","score":0.9819999933242798},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.871999979019165},{"id":"https://openalex.org/keywords/ureaplasma-urealyticum","display_name":"Ureaplasma urealyticum","score":0.968999981880188},{"id":"https://openalex.org/keywords/mycoplasma-hominis","display_name":"Mycoplasma hominis","score":1.0},{"id":"https://openalex.org/keywords/vaginal-colonization","display_name":"vaginal colonization","score":0.5270000100135803},{"id":"https://openalex.org/keywords/clindamycin","display_name":"clindamycin","score":0.8550000190734863},{"id":"https://openalex.org/keywords/antibiotic-therapy-in-pregnancy","display_name":"antibiotic therapy in pregnancy","score":0.7490000128746033}],"concepts":[{"id":"https://openalex.org/C2780206985","wikidata":"https://www.wikidata.org/wiki/Q213511","display_name":"Erythromycin","level":3,"score":0.8132961988449097},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7794525623321533},{"id":"https://openalex.org/C2776672898","wikidata":"https://www.wikidata.org/wiki/Q137110","display_name":"Ureaplasma urealyticum","level":3,"score":0.7791192531585693},{"id":"https://openalex.org/C66322754","wikidata":"https://www.wikidata.org/wiki/Q4128476","display_name":"Birth weight","level":3,"score":0.6907679438591003},{"id":"https://openalex.org/C2779083892","wikidata":"https://www.wikidata.org/wiki/Q6692979","display_name":"Low birth weight","level":3,"score":0.6626679301261902},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.6583554744720459},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.5930298566818237},{"id":"https://openalex.org/C2909217659","wikidata":"https://www.wikidata.org/wiki/Q500151","display_name":"Ureaplasma","level":3,"score":0.5727017521858215},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.47885653376579285},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.3011850118637085},{"id":"https://openalex.org/C2778838687","wikidata":"https://www.wikidata.org/wiki/Q210975","display_name":"Mycoplasma","level":2,"score":0.2995564341545105},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06139564514160156},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001724","descriptor_name":"Birth Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002981","descriptor_name":"Clindamycin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004917","descriptor_name":"Erythromycin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005831","descriptor_name":"Genital Diseases, Female","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009175","descriptor_name":"Mycoplasma Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009180","descriptor_name":"Mycoplasmatales Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011251","descriptor_name":"Pregnancy Complications, Infectious","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D011263","descriptor_name":"Pregnancy Trimester, Third","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014509","descriptor_name":"Ureaplasma","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0020-7292(87)90105-6","doi":"https://doi.org/10.1016/0020-7292(87)90105-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0020-7292(87)90105-6","pdf_url":null,"source":{"id":"https://openalex.org/S4210216427","display_name":"International Journal of Gynecology & Obstetrics","issn_l":"0020-6695","issn":["0020-6695","0020-7292","1879-3479"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Gynecology & Obstetrics","raw_type":"journal-article"},{"id":"pmid:3543767","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3543767","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obstetrics and gynecology","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[{"id":"https://openalex.org/G5922997297","display_name":null,"funder_award_id":"HD 11924","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"}],"funders":[{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2101290709","https://openalex.org/W2014035141","https://openalex.org/W4249208659","https://openalex.org/W2033707703","https://openalex.org/W1503100812","https://openalex.org/W2395374871","https://openalex.org/W7100013359","https://openalex.org/W6996266569","https://openalex.org/W1869876577","https://openalex.org/W1998375771"],"abstract_inverted_index":{"To":[0],"test":[1],"the":[2,36,88,100,115,149,152,170,189,201,207],"hypothesis":[3],"that":[4,184],"treatment":[5,109,185],"with":[6,33,78,84,110,122,168,186],"antibiotics":[7],"prevents":[8,192],"low":[9,193],"birth":[10,96,119,126,153,171,194],"weight,":[11],"pregnant":[12,198],"women":[13,107,135,143,166],"whose":[14,108,144],"vaginal":[15],"cultures":[16],"contained":[17],"Ureaplasma":[18],"urealyticum":[19,213],"or":[20,48,54,64,98,160],"Mycoplasma":[21],"hominis":[22],"(or":[23],"both)":[24],"and":[25],"who":[26],"gave":[27,118],"written":[28],"informed":[29],"consent":[30],"were":[31],"treated":[32,167],"one":[34],"of":[35,44,57,102,155,209],"following:":[37],"identical":[38],"looking":[39],"capsules":[40],"containing":[41],"250":[42],"mg":[43,56],"either":[45],"erythromycin":[46,85,111,145,187,210],"estolate":[47],"stearate":[49],"(active":[50,60],"against":[51,61],"U":[52,212],"urealyticum),":[53],"150":[55],"clindamycin":[58,79],"hydrochloride":[59],"M":[62],"hominis),":[63],"placebo,":[65,169],"four":[66],"times":[67],"daily":[68],"for":[69,173],"six":[70],"weeks":[71],"in":[72,114,142,165,196],"a":[73,123],"randomized":[74],"double-blind":[75],"study.":[76],"Treatment":[77,83],"had":[80,91],"no":[81,92],"effect.":[82],"initiated":[86,113],"during":[87,148,188],"second":[89],"trimester":[90,117,191],"effect":[93,202],"on":[94,99,211],"mean":[95,125],"weight":[97,127,195],"frequency":[101],"low-birth-weight":[103,174],"infants.":[104],"In":[105],"contrast,":[106],"was":[112,146,162,176],"third":[116,150,190],"to":[120,133,206],"infants":[121,131,156,175],"heavier":[124],"(3331":[128],"g)":[129,137],"than":[130],"born":[132],"placebo-treated":[134],"(3187":[136],"(P":[138,178],"=":[139,179],".042).":[140],"Similarly,":[141],"begun":[147],"trimester,":[151],"rate":[154,172],"weighing":[157],"2500":[158],"g":[159],"less":[161],"3%,":[163],"whereas":[164],"12%":[177],".047).":[180],"These":[181],"data":[182],"suggest":[183],"mycoplasma-colonized":[197],"women.":[199],"Whether":[200],"is":[203,214],"due":[204],"solely":[205],"action":[208],"uncertain.":[215]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}