{"id":"https://openalex.org/W2011483047","doi":"https://doi.org/10.1016/0003-9861(66)90429-2","title":"Control of one-carbon metabolism in a methionine-B12 auxotroph of Escherichia coli","display_name":"Control of one-carbon metabolism in a methionine-B12 auxotroph of Escherichia coli","publication_year":1966,"publication_date":"1966-11-01","ids":{"openalex":"https://openalex.org/W2011483047","doi":"https://doi.org/10.1016/0003-9861(66)90429-2","mag":"2011483047","pmid":"https://pubmed.ncbi.nlm.nih.gov/5339713"},"language":"en","primary_location":{"id":"doi:10.1016/0003-9861(66)90429-2","doi":"https://doi.org/10.1016/0003-9861(66)90429-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0003-9861(66)90429-2","pdf_url":null,"source":{"id":"https://openalex.org/S153476765","display_name":"Archives of Biochemistry and Biophysics","issn_l":"0003-9861","issn":["0003-9861","1096-0384"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Biochemistry and Biophysics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065479618","display_name":"Robert T. Taylor","orcid":"https://orcid.org/0000-0003-2782-4272","observed_orcids":["https://orcid.org/0000-0003-2782-4272"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert T. Taylor","raw_affiliation_strings":["Laboratory of Clinical Biochemistry, National Heart Institute, National Institutes of Health, Bethesda, Maryland 20014 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Biochemistry, National Heart Institute, National Institutes of Health, Bethesda, Maryland 20014 U.S.A","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080825378","display_name":"Herbert W. Dickerman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Herbert Dickerman","raw_affiliation_strings":["Laboratory of Clinical Biochemistry, National Heart Institute, National Institutes of Health, Bethesda, Maryland 20014 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Biochemistry, National Heart Institute, National Institutes of Health, Bethesda, Maryland 20014 U.S.A","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041730312","display_name":"Herbert Weissbach","orcid":"https://orcid.org/0000-0002-8977-084X","observed_orcids":["https://orcid.org/0000-0002-8977-084X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Herbert Weissbach","raw_affiliation_strings":["Laboratory of Clinical Biochemistry, National Heart Institute, National Institutes of Health, Bethesda, Maryland 20014 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Biochemistry, National Heart Institute, National Institutes of Health, Bethesda, Maryland 20014 U.S.A","institution_ids":["https://openalex.org/I1299303238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1299303238"],"apc_list":{"value":3170,"currency":"USD","value_usd":3170},"apc_paid":null,"fwci":5.7517,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.9478091,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"117","issue":"2","first_page":"405","last_page":"412"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.6342999935150146,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.6342999935150146,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12827","display_name":"Biochemical and Molecular Research","score":0.33809998631477356,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12441","display_name":"Porphyrin Metabolism and Disorders","score":0.015699999406933784,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/one-carbon-metabolism","display_name":"one-carbon metabolism","score":0.9980000257492065},{"id":"https://openalex.org/keywords/methionine-auxotrophy","display_name":"methionine auxotrophy","score":0.8220000267028809},{"id":"https://openalex.org/keywords/methionine-repression","display_name":"methionine repression","score":0.7630000114440918},{"id":"https://openalex.org/keywords/competitive-inhibition","display_name":"competitive inhibition","score":0.7960000038146973},{"id":"https://openalex.org/keywords/triphosphopyridine-nucleotide","display_name":"triphosphopyridine nucleotide","score":0.925000011920929},{"id":"https://openalex.org/keywords/serine-incorporation","display_name":"serine incorporation","score":0.7229999899864197},{"id":"https://openalex.org/keywords/escherichia-coli-k-12","display_name":"Escherichia coli K-12","score":0.8679999709129333}],"concepts":[{"id":"https://openalex.org/C2780912031","wikidata":"https://www.wikidata.org/wiki/Q180341","display_name":"Methionine","level":3,"score":0.724561870098114},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.7150244116783142},{"id":"https://openalex.org/C169586020","wikidata":"https://www.wikidata.org/wiki/Q3780159","display_name":"Purine metabolism","level":3,"score":0.6798132061958313},{"id":"https://openalex.org/C20950039","wikidata":"https://www.wikidata.org/wiki/Q578111","display_name":"Auxotrophy","level":4,"score":0.5911856293678284},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.5395945310592651},{"id":"https://openalex.org/C2776476023","wikidata":"https://www.wikidata.org/wiki/Q188261","display_name":"Purine","level":3,"score":0.5378737449645996},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5025708675384521},{"id":"https://openalex.org/C80315684","wikidata":"https://www.wikidata.org/wiki/Q2737583","display_name":"Methionine synthase","level":4,"score":0.4788667857646942},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.4628962576389313},{"id":"https://openalex.org/C160560785","wikidata":"https://www.wikidata.org/wiki/Q21115950","display_name":"Glycine cleavage system","level":4,"score":0.42087340354919434},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41824784874916077},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.3273433744907379},{"id":"https://openalex.org/C2776414213","wikidata":"https://www.wikidata.org/wiki/Q183290","display_name":"Serine","level":3,"score":0.3121050000190735},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.2512088119983673},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002244","descriptor_name":"Carbon","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002247","descriptor_name":"Carbon Isotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004794","descriptor_name":"Enzyme Repression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005246","descriptor_name":"Feedback","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005492","descriptor_name":"Folic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008025","descriptor_name":"Ligases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008715","descriptor_name":"Methionine","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010088","descriptor_name":"Oxidoreductases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013762","descriptor_name":"Tetrahydrofolate Dehydrogenase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013936","descriptor_name":"Thymidine","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D014166","descriptor_name":"Transferases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014805","descriptor_name":"Vitamin B 12","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0003-9861(66)90429-2","doi":"https://doi.org/10.1016/0003-9861(66)90429-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0003-9861(66)90429-2","pdf_url":null,"source":{"id":"https://openalex.org/S153476765","display_name":"Archives of Biochemistry and Biophysics","issn_l":"0003-9861","issn":["0003-9861","1096-0384"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Biochemistry and Biophysics","raw_type":"journal-article"},{"id":"pmid:5339713","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5339713","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of biochemistry and biophysics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W34615180","https://openalex.org/W89635679","https://openalex.org/W123782515","https://openalex.org/W133449313","https://openalex.org/W149446248","https://openalex.org/W182113898","https://openalex.org/W205467678","https://openalex.org/W244386701","https://openalex.org/W1486691724","https://openalex.org/W1502413765","https://openalex.org/W1763075096","https://openalex.org/W1775749144","https://openalex.org/W1799960502","https://openalex.org/W1964072856","https://openalex.org/W1982995724","https://openalex.org/W2026912546","https://openalex.org/W2028737057","https://openalex.org/W2042519908","https://openalex.org/W2056782631","https://openalex.org/W2060535373","https://openalex.org/W2071945923","https://openalex.org/W2076897347","https://openalex.org/W2154600091","https://openalex.org/W2426140507","https://openalex.org/W3119999078"],"related_works":["https://openalex.org/W1645722049","https://openalex.org/W2029517017","https://openalex.org/W2082201443","https://openalex.org/W1987160351","https://openalex.org/W1985825472","https://openalex.org/W2093475929","https://openalex.org/W1982718030","https://openalex.org/W2076897347","https://openalex.org/W2045766509","https://openalex.org/W7097258331"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}