{"id":"https://openalex.org/W2011478741","doi":"https://doi.org/10.1002/dta.234","title":"Reporting and managing elevated testosterone/epitestosterone ratios\u2014Novel aspects after five years' experience","display_name":"Reporting and managing elevated testosterone/epitestosterone ratios\u2014Novel aspects after five years' experience","publication_year":2010,"publication_date":"2010-11-01","ids":{"openalex":"https://openalex.org/W2011478741","doi":"https://doi.org/10.1002/dta.234","mag":"2011478741","pmid":"https://pubmed.ncbi.nlm.nih.gov/21204295"},"language":"en","primary_location":{"id":"doi:10.1002/dta.234","doi":"https://doi.org/10.1002/dta.234","is_oa":false,"landing_page_url":"https://doi.org/10.1002/dta.234","pdf_url":null,"source":{"id":"https://openalex.org/S36361591","display_name":"Drug Testing and Analysis","issn_l":"1942-7603","issn":["1942-7603","1942-7611"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug Testing and Analysis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037454586","display_name":"Ute Mareck","orcid":"https://orcid.org/0000-0003-2531-4121","observed_orcids":["https://orcid.org/0000-0003-2531-4121"]},"institutions":[{"id":"https://openalex.org/I137533716","display_name":"German Sport University Cologne","ror":"https://ror.org/0189raq88","country_code":"DE","type":"education","lineage":["https://openalex.org/I137533716"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Ute Mareck","raw_affiliation_strings":["Institute of Biochemistry, German Sport University Cologne, Am Sportpark M\u00fcngersdorf 6, Cologne, Germany. u.mareck@biochem.dshs-koeln.de","Institute of Biochemistry, German Sport University Cologne Cologne Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biochemistry, German Sport University Cologne, Am Sportpark M\u00fcngersdorf 6, Cologne, Germany. u.mareck@biochem.dshs-koeln.de","institution_ids":["https://openalex.org/I137533716"]},{"raw_affiliation_string":"Institute of Biochemistry, German Sport University Cologne Cologne Germany","institution_ids":["https://openalex.org/I137533716"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111549759","display_name":"Hans Geyer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137533716","display_name":"German Sport University Cologne","ror":"https://ror.org/0189raq88","country_code":"DE","type":"education","lineage":["https://openalex.org/I137533716"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hans Geyer","raw_affiliation_strings":["Institute of Biochemistry, German Sport University Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biochemistry, German Sport University Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I137533716"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009885051","display_name":"Gregor Fu\u00dfh\u00f6ller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137533716","display_name":"German Sport University Cologne","ror":"https://ror.org/0189raq88","country_code":"DE","type":"education","lineage":["https://openalex.org/I137533716"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Gregor Fu\u00dfh\u00f6ller","raw_affiliation_strings":["Institute of Biochemistry, German Sport University Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biochemistry, German Sport University Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I137533716"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002572506","display_name":"Anne Schwenke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137533716","display_name":"German Sport University Cologne","ror":"https://ror.org/0189raq88","country_code":"DE","type":"education","lineage":["https://openalex.org/I137533716"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Anne Schwenke","raw_affiliation_strings":["Institute of Biochemistry, German Sport University Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biochemistry, German Sport University Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I137533716"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075607371","display_name":"Nadine Haenelt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137533716","display_name":"German Sport University Cologne","ror":"https://ror.org/0189raq88","country_code":"DE","type":"education","lineage":["https://openalex.org/I137533716"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Nadine Haenelt","raw_affiliation_strings":["Institute of Biochemistry, German Sport University Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biochemistry, German Sport University Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I137533716"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078812809","display_name":"Thomas Piper","orcid":"https://orcid.org/0000-0002-7462-6693","observed_orcids":["https://orcid.org/0000-0002-7462-6693"]},"institutions":[{"id":"https://openalex.org/I137533716","display_name":"German Sport University Cologne","ror":"https://ror.org/0189raq88","country_code":"DE","type":"education","lineage":["https://openalex.org/I137533716"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thomas Piper","raw_affiliation_strings":["Institute of Biochemistry, German Sport University Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biochemistry, German Sport University Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I137533716"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017490382","display_name":"Mario Thevis","orcid":"https://orcid.org/0000-0002-1535-6451","observed_orcids":["https://orcid.org/0000-0002-1535-6451","https://orcid.org/0000-0001-5972-8854"]},"institutions":[{"id":"https://openalex.org/I137533716","display_name":"German Sport University Cologne","ror":"https://ror.org/0189raq88","country_code":"DE","type":"education","lineage":["https://openalex.org/I137533716"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Mario Thevis","raw_affiliation_strings":["Institute of Biochemistry, German Sport University Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biochemistry, German Sport University Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I137533716"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036531177","display_name":"Wilhelm Sch\u00e4nzer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137533716","display_name":"German Sport University Cologne","ror":"https://ror.org/0189raq88","country_code":"DE","type":"education","lineage":["https://openalex.org/I137533716"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Wilhelm Sch\u00e4nzer","raw_affiliation_strings":["Institute of Biochemistry, German Sport University Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biochemistry, German Sport University Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I137533716"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5037454586"],"corresponding_institution_ids":["https://openalex.org/I137533716"],"apc_list":{"value":4440,"currency":"USD","value_usd":4440},"apc_paid":null,"fwci":12.4149,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.98142872,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"2","issue":"11-12","first_page":"637","last_page":"642"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12700","display_name":"Doping in Sports","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3312","display_name":"Sociology and Political Science"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T12700","display_name":"Doping in Sports","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3312","display_name":"Sociology and Political Science"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T13338","display_name":"Pharmacological Effects and Assays","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/testosterone-epitestosterone-ratio","display_name":"testosterone/epitestosterone ratio","score":0.9940000176429749},{"id":"https://openalex.org/keywords/doping-control","display_name":"doping control","score":0.6290000081062317},{"id":"https://openalex.org/keywords/isotope-ratio-mass-spectrometry","display_name":"isotope ratio mass spectrometry","score":0.9440000057220459},{"id":"https://openalex.org/keywords/reporting-thresholds","display_name":"reporting thresholds","score":0.6769999861717224},{"id":"https://openalex.org/keywords/luteinizing-hormone","display_name":"luteinizing hormone","score":0.8339999914169312},{"id":"https://openalex.org/keywords/strength-sports","display_name":"strength sports","score":0.7900000214576721},{"id":"https://openalex.org/keywords/urine-analysis","display_name":"urine analysis","score":0.4519999921321869},{"id":"https://openalex.org/keywords/adverse-analytical-findings","display_name":"adverse analytical findings","score":0.5070000290870667}],"concepts":[{"id":"https://openalex.org/C2779341496","wikidata":"https://www.wikidata.org/wiki/Q416852","display_name":"Epitestosterone","level":4,"score":0.906784176826477},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.6670070290565491},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40379852056503296},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.37509089708328247},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35066500306129456},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2849096953868866},{"id":"https://openalex.org/C2777911890","wikidata":"https://www.wikidata.org/wiki/Q62614","display_name":"Androgen","level":3,"score":0.18028992414474487},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.08825650811195374}],"mesh":[{"descriptor_ui":"D004300","descriptor_name":"Doping in Sports","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004845","descriptor_name":"Epitestosterone","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D015813","descriptor_name":"Substance Abuse Detection","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015813","descriptor_name":"Substance Abuse Detection","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1002/dta.234","doi":"https://doi.org/10.1002/dta.234","is_oa":false,"landing_page_url":"https://doi.org/10.1002/dta.234","pdf_url":null,"source":{"id":"https://openalex.org/S36361591","display_name":"Drug Testing and Analysis","issn_l":"1942-7603","issn":["1942-7603","1942-7611"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug Testing and Analysis","raw_type":"journal-article"},{"id":"pmid:21204295","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21204295","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug testing and analysis","raw_type":"Journal Article"},{"id":"pmh:oai:USBKOELN.ub.uni-koeln.de:49318","doi":null,"is_oa":false,"landing_page_url":"https://kups.ub.uni-koeln.de/49318/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400371","display_name":"K\u00f6lner Universit\u00e4ts PublikationsServer (Universit\u00e4t zu K\u00f6ln)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210115942","host_organization_name":"Rhenish Institute for Environmental Research","host_organization_lineage":["https://openalex.org/I4210115942"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"doc-type:article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W165482171","https://openalex.org/W2012469068","https://openalex.org/W2016671902","https://openalex.org/W2017591945","https://openalex.org/W2020660612","https://openalex.org/W2022441024","https://openalex.org/W2032050006","https://openalex.org/W2068448528","https://openalex.org/W2073778607","https://openalex.org/W2077773041","https://openalex.org/W2091496356","https://openalex.org/W2099393074","https://openalex.org/W2104218121","https://openalex.org/W2105853715","https://openalex.org/W2106983444","https://openalex.org/W2112628426","https://openalex.org/W2113726911","https://openalex.org/W2117706127","https://openalex.org/W2122772347","https://openalex.org/W2602272053","https://openalex.org/W4300744075"],"related_works":["https://openalex.org/W2073190337","https://openalex.org/W7096460678","https://openalex.org/W2017591945","https://openalex.org/W2013981842","https://openalex.org/W2003837879","https://openalex.org/W2605778951","https://openalex.org/W2108532493","https://openalex.org/W2032050006","https://openalex.org/W2270304037","https://openalex.org/W1138924270"],"abstract_inverted_index":{"The":[0],"testosterone/epitestosterone":[1],"(T/E)":[2],"ratio":[3,76,94,155],"was":[4,32],"implemented":[5],"as":[6,156],"an":[7,17],"indirect":[8],"parameter":[9,158],"for":[10,100,174,204,215],"the":[11,28,51,117,127,149,153,161,175,178,184,201],"detection":[12,176],"of":[13,56,67,74,82,91,112,120,152,177,180,186,238],"testosterone":[14,106,181],"administration":[15],"with":[16,134],"empirically":[18],"established":[19],"threshold":[20,31,130,202],"value":[21],"at":[22],"T/E":[23,29,62,93,114,128,135,154,205,218],"=":[24],"6.":[25,220],"In":[26],"2005,":[27],"reporting":[30,129],"lowered":[33],"from":[34,86,206,247],"six":[35],"to":[36,103,199,208],"four.":[37],"Between":[38],"2005":[39],"and":[40,80,139,148,210,235],"2009,":[41],"63":[42],"510":[43],"doping":[44],"control":[45],"urine":[46,132],"samples":[47,111],"were":[48,69],"analyzed":[49],"in":[50,233,241],"Cologne":[52],"laboratory.":[53],"A":[54,170],"total":[55],"1442":[57],"specimens":[58,133,216],"(2.3%)":[59],"showed":[60,95],"a":[61,96],">":[63,219],"4;":[64],"80":[65],"(5.5%)":[66],"which":[68,83],"tested":[70],"positive":[71,145],"by":[72,125],"means":[73],"isotope":[75],"mass":[77],"spectrometry":[78],"(IRMS);":[79],"most":[81],"(68)":[84],"originated":[85],"strength":[87],"sport":[88],"disciplines.":[89],"Specimens":[90],"high":[92],"much":[97],"higher":[98],"probability":[99],"being":[101],"confirmed":[102],"contain":[104],"exogenous":[105],"using":[107],"IRMS":[108,146,213,224],"analysis":[109,214,225],"than":[110],"low":[113],"values.":[115],"Considering":[116],"small":[118],"number":[119],"adverse":[121],"analytical":[122],"findings":[123],"triggered":[124],"lowering":[126],"(978":[131],"ratios":[136],"between":[137],"4":[138,143,207],"6":[140,209],"yielded":[141],"only":[142,166],"(0.4%)":[144],"findings)":[147],"known":[150],"limitations":[151],"discriminating":[157],"(UGT2B17":[159],"polymorphism),":[160],"currently":[162],"mandatory":[163],"approach":[164],"shows":[165],"marginal":[167],"overall":[168],"efficiency.":[169],"more":[171],"effective":[172],"tool":[173],"misuse":[179],"would":[182],"be":[183,227],"implementation":[185],"individual":[187,242],"reference":[188],"ranges.":[189],"Until":[190],"athlete":[191],"steroidal":[192],"passports":[193],"are":[194],"available,":[195],"it":[196],"is":[197],"suggested":[198],"exceed":[200],"level":[203],"perform":[211],"obligatory":[212],"showing":[217],"Further":[221],"conditions":[222],"triggering":[223],"could":[226],"suppressed":[228],"luteinizing":[229],"hormone":[230],"(LH)":[231],"values":[232],"males":[234],"disproportionate":[236],"changes":[237],"relevant":[239],"parameters":[240],"profiles":[243],"evidently":[244],"not":[245],"resulting":[246],"ethanol":[248],"consumption.":[249]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}