{"id":"https://openalex.org/W2011473929","doi":"https://doi.org/10.1378/chest.124.2.594","title":"Left Ventricular Hypertrophy Is a Common Echocardiographic Abnormality in Severe Obstructive Sleep Apnea and Reverses With Nasal Continuous Positive Airway Pressure*","display_name":"Left Ventricular Hypertrophy Is a Common Echocardiographic Abnormality in Severe Obstructive Sleep Apnea and Reverses With Nasal Continuous Positive Airway Pressure*","publication_year":2003,"publication_date":"2003-08-01","ids":{"openalex":"https://openalex.org/W2011473929","doi":"https://doi.org/10.1378/chest.124.2.594","mag":"2011473929","pmid":"https://pubmed.ncbi.nlm.nih.gov/12907548"},"language":"en","primary_location":{"id":"doi:10.1378/chest.124.2.594","doi":"https://doi.org/10.1378/chest.124.2.594","is_oa":false,"landing_page_url":"https://doi.org/10.1378/chest.124.2.594","pdf_url":null,"source":{"id":"https://openalex.org/S76900504","display_name":"CHEST Journal","issn_l":"0012-3692","issn":["0012-3692","1931-3543"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chest","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013020935","display_name":"Tom V. Cloward","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I108785884","display_name":"Intermountain Healthcare","ror":"https://ror.org/04mvr1r74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I108785884"]},{"id":"https://openalex.org/I2801996072","display_name":"LDS Hospital","ror":"https://ror.org/0360cq027","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I108785884","https://openalex.org/I2801996072"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tom V. Cloward","raw_affiliation_strings":["Intermountain Sleep Disorders Center, LDS Hospital, Salt Lake City, Utah 84143, USA. ldtclowa@ihc.com","Intermountain Sleep Disorders Center, LDS Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Intermountain Sleep Disorders Center, LDS Hospital, Salt Lake City, Utah 84143, USA. ldtclowa@ihc.com","institution_ids":["https://openalex.org/I108785884","https://openalex.org/I2801996072"]},{"raw_affiliation_string":"Intermountain Sleep Disorders Center, LDS Hospital","institution_ids":["https://openalex.org/I108785884","https://openalex.org/I2801996072"]}]},{"author_position":"middle","author":{"id":null,"display_name":"James M. Walker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I108785884","display_name":"Intermountain Healthcare","ror":"https://ror.org/04mvr1r74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I108785884"]},{"id":"https://openalex.org/I2801996072","display_name":"LDS Hospital","ror":"https://ror.org/0360cq027","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I108785884","https://openalex.org/I2801996072"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James M. Walker","raw_affiliation_strings":["Intermountain Sleep Disorders Center, LDS Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Intermountain Sleep Disorders Center, LDS Hospital","institution_ids":["https://openalex.org/I108785884","https://openalex.org/I2801996072"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020490725","display_name":"Robert J. Farney","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I108785884","display_name":"Intermountain Healthcare","ror":"https://ror.org/04mvr1r74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I108785884"]},{"id":"https://openalex.org/I2801996072","display_name":"LDS Hospital","ror":"https://ror.org/0360cq027","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I108785884","https://openalex.org/I2801996072"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert J. Farney","raw_affiliation_strings":["Intermountain Sleep Disorders Center, LDS Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Intermountain Sleep Disorders Center, LDS Hospital","institution_ids":["https://openalex.org/I108785884","https://openalex.org/I2801996072"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101884435","display_name":"Jeffrey L. Anderson","orcid":"https://orcid.org/0000-0002-0825-8685","observed_orcids":["https://orcid.org/0000-0002-0825-8685"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey L. Anderson","raw_affiliation_strings":["Division of Cardiology, University of Utah, Salt Lake City, UT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, University of Utah, Salt Lake City, UT","institution_ids":["https://openalex.org/I223532165"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4160,"currency":"USD","value_usd":4160},"apc_paid":null,"fwci":5.1242,"has_fulltext":false,"cited_by_count":169,"citation_normalized_percentile":{"value":0.96039298,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"124","issue":"2","first_page":"594","last_page":"601"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/left-ventricular-hypertrophy","display_name":"left ventricular hypertrophy","score":0.8970000147819519},{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"obstructive sleep apnea","score":0.996999979019165},{"id":"https://openalex.org/keywords/continuous-positive-airway-pressure","display_name":"continuous positive airway pressure","score":0.9259999990463257},{"id":"https://openalex.org/keywords/cardiac-structural-abnormalities","display_name":"cardiac structural abnormalities","score":0.734000027179718},{"id":"https://openalex.org/keywords/left-atrial-enlargement","display_name":"left atrial enlargement","score":0.984000027179718},{"id":"https://openalex.org/keywords/right-atrial-enlargement","display_name":"right atrial enlargement","score":0.9950000047683716},{"id":"https://openalex.org/keywords/right-ventricular-hypertrophy","display_name":"right ventricular hypertrophy","score":0.996999979019165},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.5180000066757202}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9768469929695129},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7553927898406982},{"id":"https://openalex.org/C2779547634","wikidata":"https://www.wikidata.org/wiki/Q5165502","display_name":"Continuous positive airway pressure","level":3,"score":0.7461286783218384},{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.6619798541069031},{"id":"https://openalex.org/C2776002628","wikidata":"https://www.wikidata.org/wiki/Q1628627","display_name":"Left ventricular hypertrophy","level":3,"score":0.6569353342056274},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6504278182983398},{"id":"https://openalex.org/C2778205975","wikidata":"https://www.wikidata.org/wiki/Q1754874","display_name":"Polysomnography","level":3,"score":0.6395960450172424},{"id":"https://openalex.org/C2777627335","wikidata":"https://www.wikidata.org/wiki/Q6516936","display_name":"Left atrial enlargement","level":4,"score":0.5398511290550232},{"id":"https://openalex.org/C2779740085","wikidata":"https://www.wikidata.org/wiki/Q2397680","display_name":"Interventricular septum","level":3,"score":0.5046848058700562},{"id":"https://openalex.org/C167414201","wikidata":"https://www.wikidata.org/wiki/Q1955391","display_name":"Muscle hypertrophy","level":2,"score":0.49148881435394287},{"id":"https://openalex.org/C2776779939","wikidata":"https://www.wikidata.org/wiki/Q1479485","display_name":"Hypoxemia","level":2,"score":0.4485149681568146},{"id":"https://openalex.org/C2777935920","wikidata":"https://www.wikidata.org/wiki/Q213600","display_name":"Sleep apnea","level":2,"score":0.4253823757171631},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.4069015681743622},{"id":"https://openalex.org/C2781326671","wikidata":"https://www.wikidata.org/wiki/Q754424","display_name":"Apnea","level":2,"score":0.3936278820037842},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.34838247299194336},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.23520532250404358},{"id":"https://openalex.org/C2775914520","wikidata":"https://www.wikidata.org/wiki/Q12335414","display_name":"Sinus rhythm","level":3,"score":0.11773860454559326},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000860","descriptor_name":"Hypoxia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D001784","descriptor_name":"Blood Gas Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011175","descriptor_name":"Positive-Pressure Respiration","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017286","descriptor_name":"Polysomnography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017379","descriptor_name":"Hypertrophy, Left Ventricular","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D017379","descriptor_name":"Hypertrophy, Left Ventricular","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1378/chest.124.2.594","doi":"https://doi.org/10.1378/chest.124.2.594","is_oa":false,"landing_page_url":"https://doi.org/10.1378/chest.124.2.594","pdf_url":null,"source":{"id":"https://openalex.org/S76900504","display_name":"CHEST Journal","issn_l":"0012-3692","issn":["0012-3692","1931-3543"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chest","raw_type":"journal-article"},{"id":"pmid:12907548","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12907548","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chest","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W93249052","https://openalex.org/W588588552","https://openalex.org/W1680868467","https://openalex.org/W1964458777","https://openalex.org/W1965644737","https://openalex.org/W1975240757","https://openalex.org/W1978785446","https://openalex.org/W1983692570","https://openalex.org/W1985197269","https://openalex.org/W1987663126","https://openalex.org/W1990258810","https://openalex.org/W1992890029","https://openalex.org/W1994381724","https://openalex.org/W1996167795","https://openalex.org/W1999990107","https://openalex.org/W2014020993","https://openalex.org/W2015434572","https://openalex.org/W2020713898","https://openalex.org/W2027496497","https://openalex.org/W2030541107","https://openalex.org/W2035557978","https://openalex.org/W2044045435","https://openalex.org/W2045789221","https://openalex.org/W2050134576","https://openalex.org/W2052039979","https://openalex.org/W2062246462","https://openalex.org/W2068340413","https://openalex.org/W2075479080","https://openalex.org/W2078259015","https://openalex.org/W2079522417","https://openalex.org/W2081861176","https://openalex.org/W2087225497","https://openalex.org/W2102612844","https://openalex.org/W2113300049","https://openalex.org/W2114942155","https://openalex.org/W2118855061","https://openalex.org/W2129994623","https://openalex.org/W2131733207","https://openalex.org/W2139704316","https://openalex.org/W2149992059","https://openalex.org/W2157359185","https://openalex.org/W2157869248","https://openalex.org/W2166486120","https://openalex.org/W2315113911","https://openalex.org/W2331935054","https://openalex.org/W2334499091","https://openalex.org/W2335449614","https://openalex.org/W2414562711","https://openalex.org/W2525537354","https://openalex.org/W3022302886","https://openalex.org/W3166543270","https://openalex.org/W4246117256","https://openalex.org/W4299334239"],"related_works":["https://openalex.org/W1983768144","https://openalex.org/W167460020","https://openalex.org/W2041058091","https://openalex.org/W3097830648","https://openalex.org/W2220612995","https://openalex.org/W2002578860","https://openalex.org/W2027496497","https://openalex.org/W2110931764","https://openalex.org/W4313339495","https://openalex.org/W7759213"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":13},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}