{"id":"https://openalex.org/W2011199481","doi":"https://doi.org/10.1002/hep.510290629","title":"Reversal of Type 1 Hepatorenal Syndrome With the Administration of Midodrine and Octreotide","display_name":"Reversal of Type 1 Hepatorenal Syndrome With the Administration of Midodrine and Octreotide","publication_year":1999,"publication_date":"1999-06-01","ids":{"openalex":"https://openalex.org/W2011199481","doi":"https://doi.org/10.1002/hep.510290629","mag":"2011199481","pmid":"https://pubmed.ncbi.nlm.nih.gov/10347109"},"language":"en","primary_location":{"id":"doi:10.1002/hep.510290629","doi":"https://doi.org/10.1002/hep.510290629","is_oa":true,"landing_page_url":"https://doi.org/10.1002/hep.510290629","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hep.510290629","source":{"id":"https://openalex.org/S156174673","display_name":"Hepatology","issn_l":"0270-9139","issn":["0270-9139","1527-3350"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2011199481"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hep.510290629","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086128451","display_name":"Paolo Angeli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Paolo Angeli","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy. pangeli@uxl.unipd.it","Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy. pangeli@uxl.unipd.it","institution_ids":["https://openalex.org/I138689650"]},{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003602875","display_name":"Roberta Volpin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Roberta Volpin","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007635069","display_name":"Giorgio Enrico Gerunda","orcid":"https://orcid.org/0000-0003-2898-1886","observed_orcids":["https://orcid.org/0000-0003-2898-1886"]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giorgio Gerunda","raw_affiliation_strings":["General Surgery Division 1st, University of Padua, Padova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"General Surgery Division 1st, University of Padua, Padova, Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019116834","display_name":"Raffaella Craighero","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Raffaella Craighero","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002700505","display_name":"Paola Roner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paola Roner","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042021975","display_name":"Roberto Merenda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Roberto Merenda","raw_affiliation_strings":["General Surgery Division 1st, University of Padua, Padova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"General Surgery Division 1st, University of Padua, Padova, Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012973759","display_name":"Piero Amodio","orcid":"https://orcid.org/0000-0002-2395-7599","observed_orcids":["https://orcid.org/0000-0002-2395-7599"]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Piero Amodio","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026789895","display_name":"A. Sticca","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonietta Sticca","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034435863","display_name":"Lorenza Caregaro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lorenza Caregaro","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059134919","display_name":"Alvise Maffei-Faccioli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alvise Maffei-Faccioli","raw_affiliation_strings":["General Surgery Division 1st, University of Padua, Padova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"General Surgery Division 1st, University of Padua, Padova, Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006387483","display_name":"Angelo Gatta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Angelo Gatta","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy","institution_ids":["https://openalex.org/I138689650"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5086128451"],"corresponding_institution_ids":["https://openalex.org/I138689650"],"apc_list":{"value":2900,"currency":"USD","value_usd":2900},"apc_paid":null,"fwci":10.95,"has_fulltext":true,"cited_by_count":558,"citation_normalized_percentile":{"value":0.98842462,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":100},"biblio":{"volume":"29","issue":"6","first_page":"1690","last_page":"1697"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11967","display_name":"Electrolyte and hormonal disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-1-hepatorenal-syndrome","display_name":"hepatorenal syndrome type 1","score":0.9160000085830688},{"id":"https://openalex.org/keywords/midodrine","display_name":"midodrine","score":0.9940000176429749},{"id":"https://openalex.org/keywords/octreotide","display_name":"octreotide","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dopamine","display_name":"dopamine","score":0.7829999923706055},{"id":"https://openalex.org/keywords/liver-cirrhosis","display_name":"liver cirrhosis","score":0.7749999761581421},{"id":"https://openalex.org/keywords/renal-plasma-flow","display_name":"renal plasma flow","score":0.6830000281333923},{"id":"https://openalex.org/keywords/glomerular-filtration-rate","display_name":"glomerular filtration rate","score":0.9629999995231628},{"id":"https://openalex.org/keywords/vasopressin","display_name":"vasopressin","score":0.7110000252723694},{"id":"https://openalex.org/keywords/renin-angiotensin-system","display_name":"renin-angiotensin system","score":0.800000011920929},{"id":"https://openalex.org/keywords/liver-transplantation","display_name":"liver transplantation","score":0.6639999747276306},{"id":"https://openalex.org/keywords/albumin-infusion","display_name":"albumin infusion","score":0.6140000224113464},{"id":"https://openalex.org/keywords/vasoconstrictor-therapy","display_name":"vasoconstrictor therapy","score":0.6809999942779541}],"concepts":[{"id":"https://openalex.org/C2780081974","wikidata":"https://www.wikidata.org/wiki/Q415051","display_name":"Midodrine","level":4,"score":0.9787495136260986},{"id":"https://openalex.org/C2776988256","wikidata":"https://www.wikidata.org/wiki/Q247131","display_name":"Hepatorenal syndrome","level":3,"score":0.7855746746063232},{"id":"https://openalex.org/C2781025020","wikidata":"https://www.wikidata.org/wiki/Q419935","display_name":"Octreotide","level":3,"score":0.7469854354858398},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6387360095977783},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4620399475097656},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4313986897468567},{"id":"https://openalex.org/C2776297358","wikidata":"https://www.wikidata.org/wiki/Q407166","display_name":"Somatostatin","level":2,"score":0.14477837085723877},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.06662678718566895},{"id":"https://openalex.org/C73787029","wikidata":"https://www.wikidata.org/wiki/Q7104929","display_name":"Orthostatic vital signs","level":3,"score":0.0},{"id":"https://openalex.org/C2780496750","wikidata":"https://www.wikidata.org/wiki/Q193889","display_name":"Ascites","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000450","descriptor_name":"Aldosterone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D001201","descriptor_name":"Ascites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004231","descriptor_name":"Diuresis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004573","descriptor_name":"Electrolytes","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005765","descriptor_name":"Gastrointestinal Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005919","descriptor_name":"Glomerular Filtration Rate","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006509","descriptor_name":"Hepatitis B","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006526","descriptor_name":"Hepatitis C","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006530","descriptor_name":"Hepatorenal Syndrome","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006530","descriptor_name":"Hepatorenal Syndrome","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006530","descriptor_name":"Hepatorenal Syndrome","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008108","descriptor_name":"Liver Diseases, Alcoholic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008879","descriptor_name":"Midodrine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D012079","descriptor_name":"Renal Circulation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012083","descriptor_name":"Renin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014662","descriptor_name":"Vasoconstrictor Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D015282","descriptor_name":"Octreotide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1002/hep.510290629","doi":"https://doi.org/10.1002/hep.510290629","is_oa":true,"landing_page_url":"https://doi.org/10.1002/hep.510290629","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hep.510290629","source":{"id":"https://openalex.org/S156174673","display_name":"Hepatology","issn_l":"0270-9139","issn":["0270-9139","1527-3350"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatology","raw_type":"journal-article"},{"id":"pmid:10347109","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10347109","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatology (Baltimore, Md.)","raw_type":"Clinical Trial"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:10036164","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/10036164/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Hepatology , 29 (6) pp. 1690-1697. (1999)","raw_type":"Article"},{"id":"pmh:oai:www.research.unipd.it:11577/2467331","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11577/2467331","pdf_url":null,"source":{"id":"https://openalex.org/S4306402547","display_name":"Padua Research Archive (University of Padova)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I138689650","host_organization_name":"University of Padua","host_organization_lineage":["https://openalex.org/I138689650"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1002/hep.510290629","doi":"https://doi.org/10.1002/hep.510290629","is_oa":true,"landing_page_url":"https://doi.org/10.1002/hep.510290629","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hep.510290629","source":{"id":"https://openalex.org/S156174673","display_name":"Hepatology","issn_l":"0270-9139","issn":["0270-9139","1527-3350"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2011199481.pdf","grobid_xml":"https://content.openalex.org/works/W2011199481.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W124747732","https://openalex.org/W186442333","https://openalex.org/W1505552009","https://openalex.org/W1514685658","https://openalex.org/W1528866425","https://openalex.org/W1570138415","https://openalex.org/W1575024810","https://openalex.org/W1632973114","https://openalex.org/W1851882079","https://openalex.org/W1965713399","https://openalex.org/W1972779898","https://openalex.org/W1983255590","https://openalex.org/W1985445785","https://openalex.org/W1985483056","https://openalex.org/W1994495153","https://openalex.org/W1998860493","https://openalex.org/W1999706743","https://openalex.org/W2003959107","https://openalex.org/W2009149270","https://openalex.org/W2013950233","https://openalex.org/W2038261793","https://openalex.org/W2054641887","https://openalex.org/W2064284892","https://openalex.org/W2066609913","https://openalex.org/W2071734707","https://openalex.org/W2071905444","https://openalex.org/W2075930886","https://openalex.org/W2076655679","https://openalex.org/W2078113157","https://openalex.org/W2101250222","https://openalex.org/W2105920220","https://openalex.org/W2110705296","https://openalex.org/W2120179295","https://openalex.org/W2124700812","https://openalex.org/W2172792711","https://openalex.org/W2180845258","https://openalex.org/W2214600008","https://openalex.org/W2316756077","https://openalex.org/W2339736887","https://openalex.org/W2395555994","https://openalex.org/W2411243033","https://openalex.org/W2414514811","https://openalex.org/W2415183088","https://openalex.org/W2460393486","https://openalex.org/W2471910641","https://openalex.org/W3191020455","https://openalex.org/W4250058955","https://openalex.org/W4252281812","https://openalex.org/W4255323393","https://openalex.org/W4285719527","https://openalex.org/W4360754244"],"related_works":["https://openalex.org/W2089280745","https://openalex.org/W6986992776","https://openalex.org/W2049714815","https://openalex.org/W2479641905","https://openalex.org/W2024929331","https://openalex.org/W2978689234","https://openalex.org/W2072646675","https://openalex.org/W2280606267","https://openalex.org/W2437970948","https://openalex.org/W2110616090"],"abstract_inverted_index":{"The":[0],"aim":[1],"of":[2,10,13,16,19,50,53,71,79,85,96,115,121,133,136,145,150,204,211,239,265,302,314],"the":[3,8,11,17,48,68,76,82,89,130,141,201,212,228,240,248,255,283,299],"study":[4],"was":[5,37,171,176],"to":[6,55,93,110,307],"verify":[7],"effects":[9,193],"administration":[12,78,84,132,301],"an":[14,156,309],"inhibitor":[15],"release":[18],"endogenous":[20],"vasodilators":[21],"together":[22],"with":[23,29,39,61,75,129,152,222,271,320],"a":[24,40,112,179,223,274],"vasoconstrictor":[25],"agent":[26],"in":[27,67,159,173,182,277,318],"patients":[28,60,90,126,197,215,242,267,319],"hepatorenal":[30],"syndrome":[31],"(HRS).":[32],"This":[33,175],"new":[34],"medical":[35,42],"perspective":[36],"compared":[38],"traditional":[41],"approach":[43],"for":[44,102],"HRS,":[45],"such":[46],"as":[47],"infusion":[49],"nonpressor":[51,134],"doses":[52,135],"dopamine":[54,137,272],"produce":[56],"renal":[57,160,225,278,291],"vasodilation.":[58],"Thirteen":[59],"type":[62,315],"1":[63,316],"HRS":[64,317],"were":[65,73,108,127,194,198,244,269],"enrolled":[66],"study.":[69],"Five":[70],"them":[72,205],"treated":[74,128,270],"oral":[77],"midodrine":[80,153,303],"and":[81,106,140,154,167,188,227,254,280,293,304,311],"parenteral":[83],"octreotide.":[86],"In":[87,297],"addition,":[88],"received":[91],"50":[92],"100":[94],"mL":[95],"20%":[97],"human":[98],"albumin":[99],"solution":[100],"daily":[101,143],"20":[103,148],"days.":[104,237,262,286],"Midodrine":[105],"octreotide":[107,305],"dosed":[109],"obtain":[111],"stable":[113],"increase":[114],"at":[116],"least":[117],"15":[118],"mm":[119],"Hg":[120],"mean":[122],"arterial":[123],"pressure.":[124],"Eight":[125],"intravenous":[131],"(2-4":[138],"micrograms/kg/min)":[139],"same":[142],"amount":[144],"albumin.":[146],"After":[147],"days":[149,221],"treatment":[151,313],"octreotide,":[155],"impressive":[157],"improvement":[158],"plasma":[161,183,186,189],"flow":[162],"(RPF),":[163],"glomerular":[164],"filtration":[165],"rate,":[166],"urinary":[168],"sodium":[169],"excretion":[170],"observed":[172],"patients.":[174],"accompanied":[177],"by":[178],"significant":[180],"reduction":[181],"renin":[184],"activity,":[185],"vasopressin,":[187],"glucagon.":[190],"No":[191],"side":[192],"observed.":[195],"Three":[196],"discharged":[199,246],"from":[200,231,247,258],"hospital.":[202],"One":[203,210,238],"successfully":[206,250],"underwent":[207,251,294],"liver":[208,233,252,295],"transplantation.":[209,296],"two":[213,241],"remaining":[214],"is":[216],"still":[217],"alive":[218],"after":[219,235,260],"472":[220],"preserved":[224],"function,":[226],"other":[229,256],"died":[230,257,281],"terminal":[232],"failure":[234],"76":[236],"who":[243,268],"not":[245],"hospital":[249],"transplantation,":[253],"pneumonia":[259],"29":[261],"Seven":[263],"out":[264],"eight":[266],"experienced":[273],"progressive":[275],"deterioration":[276],"function":[279,292],"during":[282],"first":[284],"12":[285],"Only":[287],"one":[288],"patient":[289],"recovered":[290],"conclusion,":[298],"long-term":[300],"seems":[306],"be":[308],"effective":[310],"safe":[312],"cirrhosis.":[321]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":14},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":16},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":30},{"year":2014,"cited_by_count":25},{"year":2013,"cited_by_count":29},{"year":2012,"cited_by_count":31}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}