{"id":"https://openalex.org/W2011189226","doi":"https://doi.org/10.2217/bmm.11.87","title":"Energy Metabolism in Nuclear Reprogramming","display_name":"Energy Metabolism in Nuclear Reprogramming","publication_year":2011,"publication_date":"2011-11-21","ids":{"openalex":"https://openalex.org/W2011189226","doi":"https://doi.org/10.2217/bmm.11.87","mag":"2011189226","pmid":"https://pubmed.ncbi.nlm.nih.gov/22103608","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3477517"},"language":"en","primary_location":{"id":"doi:10.2217/bmm.11.87","doi":"https://doi.org/10.2217/bmm.11.87","is_oa":false,"landing_page_url":"https://doi.org/10.2217/bmm.11.87","pdf_url":null,"source":{"id":"https://openalex.org/S130557755","display_name":"Biomarkers in Medicine","issn_l":"1752-0363","issn":["1752-0363","1752-0371"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomarkers in Medicine","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3477517","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010158523","display_name":"Clifford D.L. Folmes","orcid":"https://orcid.org/0000-0002-3683-9970","observed_orcids":["https://orcid.org/0000-0002-3683-9970"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Clifford DL Folmes","raw_affiliation_strings":["Center for Regenerative Medicine and Marriott Heart Disease Research Program, MN, USA","Division of Cardiovascular Diseases,Departments of Medicine,Molecular Pharmacology and Experimental Therapeutics & Medical Genetics,Mayo Clinic,\r200 First Street SW,\rRochester,\rMN\r55905,\rUSA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Regenerative Medicine and Marriott Heart Disease Research Program, MN, USA","institution_ids":[]},{"raw_affiliation_string":"Division of Cardiovascular Diseases,Departments of Medicine,Molecular Pharmacology and Experimental Therapeutics & Medical Genetics,Mayo Clinic,\r200 First Street SW,\rRochester,\rMN\r55905,\rUSA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085716721","display_name":"Timothy J. Nelson","orcid":"https://orcid.org/0000-0002-3862-7023","observed_orcids":["https://orcid.org/0000-0002-3862-7023"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy J Nelson","raw_affiliation_strings":["Center for Regenerative Medicine and Marriott Heart Disease Research Program,\rMN,\rUSA","Division of Cardiovascular Diseases,Departments of Medicine,Molecular Pharmacology and Experimental Therapeutics & Medical Genetics,Mayo Clinic,\r200 First Street SW,\rRochester,\rMN\r55905,\rUSA","Division of Cardiovascular Diseases, Departments of Medicine, Molecular Pharmacology and Experimental Therapeutics & Medical Genetics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Regenerative Medicine and Marriott Heart Disease Research Program,\rMN,\rUSA","institution_ids":[]},{"raw_affiliation_string":"Division of Cardiovascular Diseases,Departments of Medicine,Molecular Pharmacology and Experimental Therapeutics & Medical Genetics,Mayo Clinic,\r200 First Street SW,\rRochester,\rMN\r55905,\rUSA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Division of Cardiovascular Diseases, Departments of Medicine, Molecular Pharmacology and Experimental Therapeutics & Medical Genetics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047902810","display_name":"Andr\u00e9 Terzic","orcid":"https://orcid.org/0000-0001-9210-009X","observed_orcids":["https://orcid.org/0000-0001-9210-009X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andre Terzic","raw_affiliation_strings":["Center for Regenerative Medicine and Marriott Heart Disease Research Program,\rMN,\rUSA","Division of Cardiovascular Diseases,Departments of Medicine,Molecular Pharmacology and Experimental Therapeutics & Medical Genetics,Mayo Clinic,\r200 First Street SW,\rRochester,\rMN\r55905,\rUSA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Regenerative Medicine and Marriott Heart Disease Research Program,\rMN,\rUSA","institution_ids":[]},{"raw_affiliation_string":"Division of Cardiovascular Diseases,Departments of Medicine,Molecular Pharmacology and Experimental Therapeutics & Medical Genetics,Mayo Clinic,\r200 First Street SW,\rRochester,\rMN\r55905,\rUSA","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":null,"apc_paid":null,"fwci":0.7025,"has_fulltext":false,"cited_by_count":56,"citation_normalized_percentile":{"value":0.55001539,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"5","issue":"6","first_page":"715","last_page":"729"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nuclear-reprogramming","display_name":"nuclear reprogramming","score":0.9909999966621399},{"id":"https://openalex.org/keywords/energy-metabolism","display_name":"energy metabolism","score":0.7829999923706055},{"id":"https://openalex.org/keywords/mitochondrial-biogenesis","display_name":"mitochondrial biogenesis","score":0.8149999976158142},{"id":"https://openalex.org/keywords/induced-pluripotent-stem-cells","display_name":"induced pluripotent stem cells","score":0.8399999737739563},{"id":"https://openalex.org/keywords/dedifferentiation","display_name":"dedifferentiation","score":0.7250000238418579},{"id":"https://openalex.org/keywords/glycolysis","display_name":"glycolysis","score":0.8040000200271606},{"id":"https://openalex.org/keywords/metabolic-remodeling","display_name":"metabolic remodeling","score":0.6240000128746033},{"id":"https://openalex.org/keywords/pluripotency","display_name":"pluripotency","score":0.7910000085830688},{"id":"https://openalex.org/keywords/stemness-factors","display_name":"stemness factors","score":0.5759999752044678},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.5720000267028809}],"concepts":[{"id":"https://openalex.org/C77255625","wikidata":"https://www.wikidata.org/wiki/Q402093","display_name":"Reprogramming","level":3,"score":0.8757506012916565},{"id":"https://openalex.org/C107459253","wikidata":"https://www.wikidata.org/wiki/Q674925","display_name":"Induced pluripotent stem cell","level":4,"score":0.7828181982040405},{"id":"https://openalex.org/C2777229759","wikidata":"https://www.wikidata.org/wiki/Q6881848","display_name":"Mitochondrial biogenesis","level":3,"score":0.6322535276412964},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6115298867225647},{"id":"https://openalex.org/C134305767","wikidata":"https://www.wikidata.org/wiki/Q725508","display_name":"Somatic cell","level":3,"score":0.5589994788169861},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5197564959526062},{"id":"https://openalex.org/C131934819","wikidata":"https://www.wikidata.org/wiki/Q135390","display_name":"Biogenesis","level":3,"score":0.5127359628677368},{"id":"https://openalex.org/C100206155","wikidata":"https://www.wikidata.org/wiki/Q570714","display_name":"Bioenergetics","level":3,"score":0.47913381457328796},{"id":"https://openalex.org/C21565614","wikidata":"https://www.wikidata.org/wiki/Q12149006","display_name":"Metabolomics","level":2,"score":0.47260600328445435},{"id":"https://openalex.org/C55885012","wikidata":"https://www.wikidata.org/wiki/Q4750801","display_name":"Anaerobic glycolysis","level":4,"score":0.4643568992614746},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.4410879909992218},{"id":"https://openalex.org/C6929976","wikidata":"https://www.wikidata.org/wiki/Q3771881","display_name":"Regulator","level":3,"score":0.41161128878593445},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.3566702604293823},{"id":"https://openalex.org/C20251656","wikidata":"https://www.wikidata.org/wiki/Q162643","display_name":"Glycolysis","level":3,"score":0.25974220037460327},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.23161593079566956},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.23022881150245667},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2156842052936554},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.1544145941734314},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09965988993644714},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09017902612686157},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.06142982840538025}],"mesh":[{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006019","descriptor_name":"Glycolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057026","descriptor_name":"Induced Pluripotent Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D057026","descriptor_name":"Induced Pluripotent Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D065150","descriptor_name":"Cellular Reprogramming","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.2217/bmm.11.87","doi":"https://doi.org/10.2217/bmm.11.87","is_oa":false,"landing_page_url":"https://doi.org/10.2217/bmm.11.87","pdf_url":null,"source":{"id":"https://openalex.org/S130557755","display_name":"Biomarkers in Medicine","issn_l":"1752-0363","issn":["1752-0363","1752-0371"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomarkers in Medicine","raw_type":"journal-article"},{"id":"pmid:22103608","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22103608","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomarkers in medicine","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2469881","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3477517","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3477517","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3477517","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biomark Med","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2469881","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3477517","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5919651983","display_name":"Cardioprotective Repair through Cardiopoiesis","funder_award_id":"R01HL083439","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":122,"referenced_works":["https://openalex.org/W1522323234","https://openalex.org/W1559768539","https://openalex.org/W1605149237","https://openalex.org/W1665351911","https://openalex.org/W1965785177","https://openalex.org/W1968813633","https://openalex.org/W1969015262","https://openalex.org/W1970101770","https://openalex.org/W1977049211","https://openalex.org/W1977622464","https://openalex.org/W1978880986","https://openalex.org/W1980699340","https://openalex.org/W1983594275","https://openalex.org/W1986500594","https://openalex.org/W1986595047","https://openalex.org/W1987581102","https://openalex.org/W1987774343","https://openalex.org/W1988387169","https://openalex.org/W1989312191","https://openalex.org/W1991325439","https://openalex.org/W1994689227","https://openalex.org/W1995833967","https://openalex.org/W1996365670","https://openalex.org/W2001076497","https://openalex.org/W2001144536","https://openalex.org/W2002198698","https://openalex.org/W2002248781","https://openalex.org/W2004429137","https://openalex.org/W2006691834","https://openalex.org/W2008751481","https://openalex.org/W2009826707","https://openalex.org/W2010031978","https://openalex.org/W2014058353","https://openalex.org/W2015207840","https://openalex.org/W2016906317","https://openalex.org/W2017079604","https://openalex.org/W2017521470","https://openalex.org/W2018082119","https://openalex.org/W2019019085","https://openalex.org/W2019229253","https://openalex.org/W2020072016","https://openalex.org/W2022436116","https://openalex.org/W2022936555","https://openalex.org/W2023825654","https://openalex.org/W2025192477","https://openalex.org/W2025313023","https://openalex.org/W2025738240","https://openalex.org/W2026055638","https://openalex.org/W2027635031","https://openalex.org/W2028785490","https://openalex.org/W2032234589","https://openalex.org/W2036537782","https://openalex.org/W2037146644","https://openalex.org/W2037177911","https://openalex.org/W2038463772","https://openalex.org/W2039015357","https://openalex.org/W2039605728","https://openalex.org/W2043457504","https://openalex.org/W2044035020","https://openalex.org/W2045102424","https://openalex.org/W2047015004","https://openalex.org/W2047195788","https://openalex.org/W2047637108","https://openalex.org/W2049614454","https://openalex.org/W2051070943","https://openalex.org/W2052319461","https://openalex.org/W2053153356","https://openalex.org/W2053911973","https://openalex.org/W2059223857","https://openalex.org/W2059378220","https://openalex.org/W2062222093","https://openalex.org/W2065021234","https://openalex.org/W2070672434","https://openalex.org/W2071510932","https://openalex.org/W2072451938","https://openalex.org/W2076047032","https://openalex.org/W2078193006","https://openalex.org/W2078412067","https://openalex.org/W2079695054","https://openalex.org/W2081620485","https://openalex.org/W2082344586","https://openalex.org/W2083019384","https://openalex.org/W2084037323","https://openalex.org/W2085316849","https://openalex.org/W2085701748","https://openalex.org/W2086546138","https://openalex.org/W2086663462","https://openalex.org/W2090321067","https://openalex.org/W2093540365","https://openalex.org/W2095041841","https://openalex.org/W2097259163","https://openalex.org/W2097263041","https://openalex.org/W2100873120","https://openalex.org/W2102891343","https://openalex.org/W2103612759","https://openalex.org/W2107883924","https://openalex.org/W2109628662","https://openalex.org/W2110375707","https://openalex.org/W2111920812","https://openalex.org/W2112485709","https://openalex.org/W2117284175","https://openalex.org/W2119239003","https://openalex.org/W2122826701","https://openalex.org/W2124783198","https://openalex.org/W2125987139","https://openalex.org/W2130503287","https://openalex.org/W2133810389","https://openalex.org/W2134328115","https://openalex.org/W2139147346","https://openalex.org/W2140083705","https://openalex.org/W2142046859","https://openalex.org/W2144575277","https://openalex.org/W2145544530","https://openalex.org/W2150197150","https://openalex.org/W2150994390","https://openalex.org/W2153121902","https://openalex.org/W2160694063","https://openalex.org/W2165240683","https://openalex.org/W2170254146","https://openalex.org/W2601589642","https://openalex.org/W4211085285","https://openalex.org/W4294326454"],"related_works":["https://openalex.org/W1910182523","https://openalex.org/W2019019085","https://openalex.org/W2167923229","https://openalex.org/W2108530098","https://openalex.org/W2029600421","https://openalex.org/W2159236216","https://openalex.org/W1988387169","https://openalex.org/W2125525850","https://openalex.org/W2894467698","https://openalex.org/W1972726904"],"abstract_inverted_index":{"Nuclear":[0],"reprogramming":[1],"with":[2],"stemness":[3],"factors":[4],"enables":[5],"resetting":[6,99],"of":[7,30,35,44,60,75,102],"somatic":[8,45],"differentiated":[9],"tissue":[10],"back":[11],"to":[12,41],"the":[13,93,98],"pluripotent":[14,37,76],"ground":[15],"state.":[16],"Recent":[17],"evidence":[18],"implicates":[19],"mitochondrial":[20,79],"restructuring":[21],"and":[22,33,81,100],"bioenergetic":[23],"plasticity":[24],"as":[25],"key":[26],"components":[27],"underlying":[28],"execution":[29],"orchestrated":[31],"dedifferentiation":[32],"derivation":[34],"induced":[36],"stem":[38],"cells.":[39,77],"Aerobic":[40],"anaerobic":[42],"transition":[43],"oxidative":[46],"energy":[47,82],"metabolism":[48,83],"into":[49],"a":[50,57,85],"glycolytic":[51],"metabotype":[52],"promotes":[53],"proficient":[54],"reprogramming,":[55],"establishing":[56],"novel":[58],"regulator":[59],"acquired":[61],"stemness.":[62],"Metabolomic":[63],"profiling":[64],"has":[65],"further":[66],"identified":[67],"specific":[68],"metabolic":[69],"remodeling":[70],"traits":[71],"defining":[72],"lineage":[73],"redifferentiation":[74],"Therefore,":[78],"biogenesis":[80],"comprise":[84],"vital":[86],"axis":[87],"for":[88,97],"biomarker":[89],"discovery,":[90],"intimately":[91],"reflecting":[92],"molecular":[94],"dynamics":[95],"fundamental":[96],"redirection":[101],"cell":[103],"fate.":[104]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}