{"id":"https://openalex.org/W2011152016","doi":"https://doi.org/10.14740/jmc.v5i3.1756","title":"Pigmented Villonodular Synovitis for Combined Therapy","display_name":"Pigmented Villonodular Synovitis for Combined Therapy","publication_year":2014,"publication_date":"2014-02-23","ids":{"openalex":"https://openalex.org/W2011152016","doi":"https://doi.org/10.14740/jmc.v5i3.1756","mag":"2011152016"},"language":"en","primary_location":{"id":"mag:2011152016","doi":"https://doi.org/10.14740/jmc.v5i3.1756","is_oa":false,"landing_page_url":"https://www.journalmc.org/index.php/JMC/article/view/1756/1029","pdf_url":null,"source":{"id":"https://openalex.org/S173494252","display_name":"Journal of Medical Cases","issn_l":"1923-4155","issn":["1923-4155","1923-4163"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4328135221","host_organization_name":"Elmer Press Inc.","host_organization_lineage":["https://openalex.org/P4328135221"],"host_organization_lineage_names":["Elmer Press Inc."],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Medical Cases","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030157131","display_name":"Alexander P. Rozin","orcid":"https://orcid.org/0000-0002-1220-8488","observed_orcids":["https://orcid.org/0000-0002-1220-8488"]},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I2801301638","display_name":"Rambam Health Care Campus","ror":"https://ror.org/01fm87m50","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2801301638"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Alexander Rozin","raw_affiliation_strings":["B. Shine Department of Rheumatology, Rambam Health Care Capus and Technion, Haifa"],"raw_orcid":"https://orcid.org/0000-0002-1220-8488","affiliations":[{"raw_affiliation_string":"B. Shine Department of Rheumatology, Rambam Health Care Capus and Technion, Haifa","institution_ids":["https://openalex.org/I174306211","https://openalex.org/I2801301638"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108583900","display_name":"Gabriel Nierenberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I2801301638","display_name":"Rambam Health Care Campus","ror":"https://ror.org/01fm87m50","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2801301638"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Gabriel Nierenberg","raw_affiliation_strings":["Department of Orthopedic Surgery, Rambam Health Care Capus and Technion, Haifa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedic Surgery, Rambam Health Care Capus and Technion, Haifa","institution_ids":["https://openalex.org/I174306211","https://openalex.org/I2801301638"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080559727","display_name":"Euvgeni Vlodavsky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I2801301638","display_name":"Rambam Health Care Campus","ror":"https://ror.org/01fm87m50","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2801301638"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Euvgeni Vlodavsky","raw_affiliation_strings":["Department of Pathology, Rambam Health Care Capus and Technion, Haifa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Rambam Health Care Capus and Technion, Haifa","institution_ids":["https://openalex.org/I174306211","https://openalex.org/I2801301638"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110525841","display_name":"K. Toledano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I2801301638","display_name":"Rambam Health Care Campus","ror":"https://ror.org/01fm87m50","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2801301638"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"K. Toledano","raw_affiliation_strings":["B. Shine Department of Rheumatology, Rambam Health Care Capus and Technion, Haifa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"B. Shine Department of Rheumatology, Rambam Health Care Capus and Technion, Haifa","institution_ids":["https://openalex.org/I174306211","https://openalex.org/I2801301638"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036126356","display_name":"Natanel Meushar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I2801301638","display_name":"Rambam Health Care Campus","ror":"https://ror.org/01fm87m50","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2801301638"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Natanel Meushar","raw_affiliation_strings":["Orthopedic Oncology Unit, Rambam Health Care Capus and Technion, Haifa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopedic Oncology Unit, Rambam Health Care Capus and Technion, Haifa","institution_ids":["https://openalex.org/I174306211","https://openalex.org/I2801301638"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077639789","display_name":"Kamal Yassin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I2801301638","display_name":"Rambam Health Care Campus","ror":"https://ror.org/01fm87m50","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2801301638"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Kamal Yassin","raw_affiliation_strings":["Department of Gastroenterology and Clalit Health Services, Rambam Health Care Capus and Technion, Haifa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Clalit Health Services, Rambam Health Care Capus and Technion, Haifa","institution_ids":["https://openalex.org/I174306211","https://openalex.org/I2801301638"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004320840","display_name":"Rahamim Ben-Yosef","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I2801301638","display_name":"Rambam Health Care Campus","ror":"https://ror.org/01fm87m50","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2801301638"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Rahamim Ben-Yosef","raw_affiliation_strings":["Department of Radiotherapy, Rambam Health Care Capus and Technion, Haifa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiotherapy, Rambam Health Care Capus and Technion, Haifa","institution_ids":["https://openalex.org/I174306211","https://openalex.org/I2801301638"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10535951,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":"3","first_page":"147","last_page":"151"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12800","display_name":"Musculoskeletal synovial abnormalities and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12800","display_name":"Musculoskeletal synovial abnormalities and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pigmented-villonodular-synovitis","display_name":"pigmented villonodular synovitis","score":1.0},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.7379999756813049},{"id":"https://openalex.org/keywords/external-beam-radiotherapy","display_name":"external beam radiotherapy","score":0.8560000061988831},{"id":"https://openalex.org/keywords/synovectomy","display_name":"synovectomy","score":0.8820000290870667},{"id":"https://openalex.org/keywords/salazopyrine","display_name":"salazopyrine","score":0.9129999876022339},{"id":"https://openalex.org/keywords/celecoxib","display_name":"celecoxib","score":0.9990000128746033},{"id":"https://openalex.org/keywords/knee-pain","display_name":"knee pain","score":0.7620000243186951},{"id":"https://openalex.org/keywords/synovial-hyperplasia","display_name":"synovial hyperplasia","score":0.6729999780654907},{"id":"https://openalex.org/keywords/arthroscopic-surgery","display_name":"arthroscopic surgery","score":0.7160000205039978}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9667389392852783},{"id":"https://openalex.org/C2776791232","wikidata":"https://www.wikidata.org/wiki/Q2067052","display_name":"Pigmented villonodular synovitis","level":4,"score":0.9154300689697266},{"id":"https://openalex.org/C2776467144","wikidata":"https://www.wikidata.org/wiki/Q408801","display_name":"Celecoxib","level":2,"score":0.8121973276138306},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.6552368998527527},{"id":"https://openalex.org/C2775882047","wikidata":"https://www.wikidata.org/wiki/Q971969","display_name":"Synovectomy","level":3,"score":0.6448421478271484},{"id":"https://openalex.org/C2779244835","wikidata":"https://www.wikidata.org/wiki/Q538432","display_name":"Synovitis","level":3,"score":0.6125351190567017},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.46593135595321655},{"id":"https://openalex.org/C500440147","wikidata":"https://www.wikidata.org/wiki/Q701216","display_name":"Pharmacotherapy","level":2,"score":0.4274016320705414},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22370797395706177},{"id":"https://openalex.org/C2777077863","wikidata":"https://www.wikidata.org/wiki/Q170990","display_name":"Arthritis","level":2,"score":0.2022973895072937},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.07085314393043518}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2011152016","doi":"https://doi.org/10.14740/jmc.v5i3.1756","is_oa":false,"landing_page_url":"https://www.journalmc.org/index.php/JMC/article/view/1756/1029","pdf_url":null,"source":{"id":"https://openalex.org/S173494252","display_name":"Journal of Medical Cases","issn_l":"1923-4155","issn":["1923-4155","1923-4163"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4328135221","host_organization_name":"Elmer Press Inc.","host_organization_lineage":["https://openalex.org/P4328135221"],"host_organization_lineage_names":["Elmer Press Inc."],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":"Journal of Medical Cases","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6800000071525574}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W129677173","https://openalex.org/W1825185942","https://openalex.org/W1972422676","https://openalex.org/W1972992713","https://openalex.org/W1976071069","https://openalex.org/W1995210963","https://openalex.org/W1998075425","https://openalex.org/W2012259688","https://openalex.org/W2031521702","https://openalex.org/W2041567900","https://openalex.org/W2049549283","https://openalex.org/W2055747247","https://openalex.org/W2072754871","https://openalex.org/W2088640335","https://openalex.org/W2089542591","https://openalex.org/W2097036703","https://openalex.org/W2105457206","https://openalex.org/W2107366273","https://openalex.org/W2108026943","https://openalex.org/W2112808283","https://openalex.org/W2149924737","https://openalex.org/W2159722562","https://openalex.org/W2266154765","https://openalex.org/W2279576014","https://openalex.org/W2290686005","https://openalex.org/W2299006547","https://openalex.org/W2404200081","https://openalex.org/W2412222704","https://openalex.org/W2412366410","https://openalex.org/W2420448473","https://openalex.org/W2973784984","https://openalex.org/W2987739936","https://openalex.org/W3158281136"],"related_works":[],"abstract_inverted_index":{"Pigmented":[0],"villonodular":[1],"synovitis":[2,54],"(PVNS),":[3],"inflammatory":[4],"proliferative":[5],"\t\t\tdisease":[7],"resulting":[8],"from":[9],"synovial":[10,112],"cells,":[11],"has":[12],"progressive":[13],"course":[14],"\t\t\tsimilar":[16],"neoplastic":[17],"local":[18],"expansion.":[19],"We":[20,157],"followed":[21,177],"up":[22],"a":[23,97,101],"case":[24,168],"with":[25,70,120,181],"\t\t\teffective":[27],"combined":[28,170],"therapy":[29],"for":[30],"diffuse":[31],"PVNS":[32],"despite":[33],"incomplete":[34],"\t\t\tresponse":[36],"to":[37,50,104,148,169],"its":[38],"components":[39],"and":[40,84,108,122,135,146,153,166],"reviewed":[41],"therapies":[42],"based":[43],"on":[44,114],"MedLine":[45],"\t\t\tfor":[47,80],"PVNS.":[48],"Due":[49,103],"US":[51,115],"data":[52,165],"residue":[53],"after":[55],"open":[56,175],"radical":[57],"\t\t\tsynovectomy,":[59],"we":[60],"made":[61],"decision":[62],"about":[63],"external":[64],"beam":[65],"radiotherapy.":[66],"\t\t\tPhoton":[68],"radiation":[69],"linear":[71],"accelerator":[72],"energy":[73],"of":[74,111],"6":[75],"MV":[76],"was":[77,89,124],"applied":[78],"two":[81],"fields:":[82],"anterior":[83],"posterior.":[85],"The":[86],"total":[87],"dose":[88],"20":[90],"Gy,":[91],"\t\t\tdelivered":[93],"in":[94],"2":[95],"Gy":[96],"day,":[98],"five":[99],"times":[100],"week.":[102],"postoperative":[105],"\t\t\tpain":[107],"the":[109,130,142],"rest":[110],"tissue":[113],"study,":[116],"pharmacologic":[117],"\t\t\ttherapy":[119],"salazopyrine":[121],"celecoxib":[123,154],"added.":[125],"For":[126],"several":[127],"\t\t\tweeks,":[129],"knee":[131],"pain":[132],"became":[133],"episodic":[134],"further":[136],"disappeared.":[137],"Six":[138],"\t\t\tmonths":[140],"later,":[141],"patient":[143],"feels":[144],"healthy":[145],"continues":[147],"take":[149],"\t\t\tsalazopyrine":[151],"permanently":[152],"as":[155],"needed.":[156],"conclude":[158],"high":[159],"\t\t\trate":[161],"response":[162],"analyzing":[163],"literature":[164],"our":[167],"\t\t\ttherapy:":[172],"arthroscopic":[173],"or":[174],"surgery":[176],"by":[178],"RT":[179],"along":[180],"\t\t\tcomplimentary":[183],"pharmacotherapy.":[184],"J":[189],"Med":[190],"Cases.":[191],"2014;5(3):147-151":[192],"doi:":[195],"http://dx.doi.org/10.14740/jmc1656e":[196]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2025-10-10T00:00:00"}
