{"id":"https://openalex.org/W2011151996","doi":"https://doi.org/10.1007/s001250051341","title":"New insights into sympathetic regulation of glucose and fat metabolism","display_name":"New insights into sympathetic regulation of glucose and fat metabolism","publication_year":2000,"publication_date":"2000-05-02","ids":{"openalex":"https://openalex.org/W2011151996","doi":"https://doi.org/10.1007/s001250051341","mag":"2011151996","pmid":"https://pubmed.ncbi.nlm.nih.gov/10855527"},"language":"en","primary_location":{"id":"doi:10.1007/s001250051341","doi":"https://doi.org/10.1007/s001250051341","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s001250051341","pdf_url":"https://link.springer.com/content/pdf/10.1007/s001250051341.pdf","source":{"id":"https://openalex.org/S104375418","display_name":"Diabetologia","issn_l":"0012-186X","issn":["0012-186X","1432-0428"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2011151996"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://link.springer.com/content/pdf/10.1007/s001250051341.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018040232","display_name":"Katsunori Nonogaki","orcid":"https://orcid.org/0000-0001-8076-7073","observed_orcids":["https://orcid.org/0000-0001-8076-7073"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"K. Nonogaki","raw_affiliation_strings":["Department of Psychiatry, University of California at San Francisco, 94143-0984, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of California at San Francisco, 94143-0984, USA","institution_ids":["https://openalex.org/I180670191"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5018040232"],"corresponding_institution_ids":["https://openalex.org/I180670191"],"apc_list":{"value":3490,"currency":"USD","value_usd":3490},"apc_paid":null,"fwci":2.4519,"has_fulltext":true,"cited_by_count":593,"citation_normalized_percentile":{"value":0.94392523,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"43","issue":"5","first_page":"533","last_page":"549"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.7886000275611877,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.7886000275611877,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.11710000038146973,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.05550000071525574,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sympathetic-nervous-system","display_name":"sympathetic nervous system","score":0.9980000257492065},{"id":"https://openalex.org/keywords/glucose-metabolism","display_name":"glucose metabolism","score":0.9909999966621399},{"id":"https://openalex.org/keywords/fat-metabolism","display_name":"fat metabolism","score":0.9729999899864197},{"id":"https://openalex.org/keywords/norepinephrine","display_name":"norepinephrine","score":0.9890000224113464},{"id":"https://openalex.org/keywords/epinephrine","display_name":"epinephrine","score":1.0},{"id":"https://openalex.org/keywords/hepatic-glucose-production","display_name":"hepatic glucose production","score":0.8539999723434448},{"id":"https://openalex.org/keywords/insulin-secretion","display_name":"insulin secretion","score":0.8500000238418579},{"id":"https://openalex.org/keywords/catecholamines","display_name":"catecholamines","score":0.6899999976158142},{"id":"https://openalex.org/keywords/thermogenesis","display_name":"thermogenesis","score":0.9480000138282776},{"id":"https://openalex.org/keywords/lipolysis","display_name":"lipolysis","score":1.0},{"id":"https://openalex.org/keywords/beta3-adrenergic-receptor","display_name":"beta3-adrenergic receptor","score":0.9449999928474426},{"id":"https://openalex.org/keywords/leptin","display_name":"leptin","score":0.9819999933242798},{"id":"https://openalex.org/keywords/serotonin-5-ht2c-receptor","display_name":"serotonin 5-HT2C receptor","score":0.9470000267028809},{"id":"https://openalex.org/keywords/satiety","display_name":"satiety","score":0.8840000033378601},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.902999997138977},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9049999713897705},{"id":"https://openalex.org/keywords/insulin-independent-glucose-uptake","display_name":"insulin-independent glucose uptake","score":0.7049999833106995}],"concepts":[{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.9012140035629272},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8882849216461182},{"id":"https://openalex.org/C2776533406","wikidata":"https://www.wikidata.org/wiki/Q187215","display_name":"Sympathetic nervous system","level":3,"score":0.7083181738853455},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.5952855348587036},{"id":"https://openalex.org/C151279926","wikidata":"https://www.wikidata.org/wiki/Q965695","display_name":"Thermogenesis","level":3,"score":0.5921839475631714},{"id":"https://openalex.org/C2775859304","wikidata":"https://www.wikidata.org/wiki/Q132621","display_name":"Epinephrine","level":2,"score":0.5519775152206421},{"id":"https://openalex.org/C2780613262","wikidata":"https://www.wikidata.org/wiki/Q223739","display_name":"Leptin","level":3,"score":0.5422760248184204},{"id":"https://openalex.org/C17093226","wikidata":"https://www.wikidata.org/wiki/Q2734081","display_name":"Carbohydrate metabolism","level":2,"score":0.5259799361228943},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.500995397567749},{"id":"https://openalex.org/C2778514916","wikidata":"https://www.wikidata.org/wiki/Q186242","display_name":"Norepinephrine","level":3,"score":0.4976809322834015},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.4884163737297058},{"id":"https://openalex.org/C2777866211","wikidata":"https://www.wikidata.org/wiki/Q5572349","display_name":"Glucose uptake","level":3,"score":0.44138777256011963},{"id":"https://openalex.org/C140985366","wikidata":"https://www.wikidata.org/wiki/Q898489","display_name":"Lipolysis","level":3,"score":0.4293230473995209},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.25538647174835205},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.18641504645347595},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.11607706546783447},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.06562873721122742}],"mesh":[{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001341","descriptor_name":"Autonomic Nervous System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001342","descriptor_name":"Autonomic Nervous System Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001342","descriptor_name":"Autonomic Nervous System Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009638","descriptor_name":"Norepinephrine","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D013564","descriptor_name":"Sympathetic Nervous System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020738","descriptor_name":"Leptin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D050356","descriptor_name":"Lipid Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s001250051341","doi":"https://doi.org/10.1007/s001250051341","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s001250051341","pdf_url":"https://link.springer.com/content/pdf/10.1007/s001250051341.pdf","source":{"id":"https://openalex.org/S104375418","display_name":"Diabetologia","issn_l":"0012-186X","issn":["0012-186X","1432-0428"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"journal-article"},{"id":"pmid:10855527","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10855527","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1007/s001250051341","doi":"https://doi.org/10.1007/s001250051341","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s001250051341","pdf_url":"https://link.springer.com/content/pdf/10.1007/s001250051341.pdf","source":{"id":"https://openalex.org/S104375418","display_name":"Diabetologia","issn_l":"0012-186X","issn":["0012-186X","1432-0428"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2011151996.pdf","grobid_xml":"https://content.openalex.org/works/W2011151996.grobid-xml"},"referenced_works_count":110,"referenced_works":["https://openalex.org/W1260067689","https://openalex.org/W1486463812","https://openalex.org/W1498791370","https://openalex.org/W1572997382","https://openalex.org/W1580569338","https://openalex.org/W1631449371","https://openalex.org/W1870380602","https://openalex.org/W1924583624","https://openalex.org/W1967078210","https://openalex.org/W1967359474","https://openalex.org/W1968509617","https://openalex.org/W1969835310","https://openalex.org/W1970934755","https://openalex.org/W1973327917","https://openalex.org/W1973351125","https://openalex.org/W1975624728","https://openalex.org/W1978777870","https://openalex.org/W1978786033","https://openalex.org/W1985908429","https://openalex.org/W1987355039","https://openalex.org/W1988115040","https://openalex.org/W1990433634","https://openalex.org/W1990949140","https://openalex.org/W1991974510","https://openalex.org/W1993639795","https://openalex.org/W1997139991","https://openalex.org/W1999115737","https://openalex.org/W2001716823","https://openalex.org/W2006272024","https://openalex.org/W2007482590","https://openalex.org/W2007867899","https://openalex.org/W2009037154","https://openalex.org/W2009462961","https://openalex.org/W2010142606","https://openalex.org/W2012604405","https://openalex.org/W2014042117","https://openalex.org/W2016261339","https://openalex.org/W2017124867","https://openalex.org/W2021770278","https://openalex.org/W2021895570","https://openalex.org/W2022140822","https://openalex.org/W2025731911","https://openalex.org/W2027360957","https://openalex.org/W2027718357","https://openalex.org/W2032777955","https://openalex.org/W2033189661","https://openalex.org/W2036594204","https://openalex.org/W2037447899","https://openalex.org/W2038872854","https://openalex.org/W2042405611","https://openalex.org/W2042827452","https://openalex.org/W2044138999","https://openalex.org/W2049375062","https://openalex.org/W2051559850","https://openalex.org/W2051889648","https://openalex.org/W2053965920","https://openalex.org/W2054994260","https://openalex.org/W2055956383","https://openalex.org/W2056383195","https://openalex.org/W2059330847","https://openalex.org/W2061340727","https://openalex.org/W2062073832","https://openalex.org/W2065389660","https://openalex.org/W2071511621","https://openalex.org/W2072147633","https://openalex.org/W2072167273","https://openalex.org/W2073989665","https://openalex.org/W2077168170","https://openalex.org/W2080015119","https://openalex.org/W2083116048","https://openalex.org/W2086568895","https://openalex.org/W2087996557","https://openalex.org/W2089495913","https://openalex.org/W2090592868","https://openalex.org/W2091087465","https://openalex.org/W2096299662","https://openalex.org/W2100498235","https://openalex.org/W2109311297","https://openalex.org/W2110561527","https://openalex.org/W2114343773","https://openalex.org/W2120663839","https://openalex.org/W2126095470","https://openalex.org/W2127314379","https://openalex.org/W2127717792","https://openalex.org/W2130421120","https://openalex.org/W2132874630","https://openalex.org/W2135070485","https://openalex.org/W2136975624","https://openalex.org/W2137993789","https://openalex.org/W2140143072","https://openalex.org/W2145164381","https://openalex.org/W2147062559","https://openalex.org/W2153266121","https://openalex.org/W2153730473","https://openalex.org/W2154926531","https://openalex.org/W2161186266","https://openalex.org/W2168299913","https://openalex.org/W2168317493","https://openalex.org/W2182738574","https://openalex.org/W2183595749","https://openalex.org/W2187233472","https://openalex.org/W2228975692","https://openalex.org/W2282705586","https://openalex.org/W2307947184","https://openalex.org/W2310458896","https://openalex.org/W2322463216","https://openalex.org/W2326977634","https://openalex.org/W2334787351","https://openalex.org/W2336925169","https://openalex.org/W4416702841"],"related_works":["https://openalex.org/W2147062559","https://openalex.org/W1967954429","https://openalex.org/W2050666399","https://openalex.org/W2325075792","https://openalex.org/W2015340294","https://openalex.org/W4251349930","https://openalex.org/W1904965705","https://openalex.org/W2035888566","https://openalex.org/W4389145147","https://openalex.org/W2072095498"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":18},{"year":2025,"cited_by_count":17},{"year":2024,"cited_by_count":20},{"year":2023,"cited_by_count":21},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":22},{"year":2020,"cited_by_count":33},{"year":2019,"cited_by_count":17},{"year":2018,"cited_by_count":26},{"year":2017,"cited_by_count":21},{"year":2016,"cited_by_count":32},{"year":2015,"cited_by_count":23},{"year":2014,"cited_by_count":19},{"year":2013,"cited_by_count":22},{"year":2012,"cited_by_count":29}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}