{"id":"https://openalex.org/W2011120356","doi":"https://doi.org/10.1016/s0944-5013(99)80016-0","title":"Crosslinkable prepolymer-immobilized Humicola lutea for acid proteinase biosynthesis","display_name":"Crosslinkable prepolymer-immobilized Humicola lutea for acid proteinase biosynthesis","publication_year":1999,"publication_date":"1999-09-01","ids":{"openalex":"https://openalex.org/W2011120356","doi":"https://doi.org/10.1016/s0944-5013(99)80016-0","mag":"2011120356"},"language":"en","primary_location":{"id":"doi:10.1016/s0944-5013(99)80016-0","doi":"https://doi.org/10.1016/s0944-5013(99)80016-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0944-5013(99)80016-0","pdf_url":null,"source":{"id":"https://openalex.org/S106450229","display_name":"Microbiological Research","issn_l":"0944-5013","issn":["0944-5013","1618-0623"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiological Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041852146","display_name":"\u041f\u0435\u043d\u043a\u0430 \u0410\u043b\u0435\u043a\u0441\u0438\u0435\u0432\u0430","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24768866","display_name":"Bulgarian Academy of Sciences","ror":"https://ror.org/01x8hew03","country_code":"BG","type":"government","lineage":["https://openalex.org/I24768866"]}],"countries":["BG"],"is_corresponding":true,"raw_author_name":"Penka P. Aleksieva","raw_affiliation_strings":["Bulgarian Academy of Sciences, Institute of Microbiology, Georgy Bonchev Str. B126, 1113 Sofia, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bulgarian Academy of Sciences, Institute of Microbiology, Georgy Bonchev Str. B126, 1113 Sofia, Bulgaria","institution_ids":["https://openalex.org/I24768866"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041670435","display_name":"E. Petricheva","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088296","display_name":"Institute of Polymers","ror":"https://ror.org/006ae1882","country_code":"BG","type":"facility","lineage":["https://openalex.org/I24768866","https://openalex.org/I4210088296"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"E. Petricheva","raw_affiliation_strings":["Scientific Research Centre of Specialty Polymers, Kl. Ohridski Str. 4A, 1756 Sofia, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Scientific Research Centre of Specialty Polymers, Kl. Ohridski Str. 4A, 1756 Sofia, Bulgaria","institution_ids":["https://openalex.org/I4210088296"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059899752","display_name":"Lilia Michailova","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24768866","display_name":"Bulgarian Academy of Sciences","ror":"https://ror.org/01x8hew03","country_code":"BG","type":"government","lineage":["https://openalex.org/I24768866"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"L. Michailova","raw_affiliation_strings":["Bulgarian Academy of Sciences, Institute of Microbiology, Georgy Bonchev Str. B126, 1113 Sofia, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bulgarian Academy of Sciences, Institute of Microbiology, Georgy Bonchev Str. B126, 1113 Sofia, Bulgaria","institution_ids":["https://openalex.org/I24768866"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047036893","display_name":"Hristo Konstantinov","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088296","display_name":"Institute of Polymers","ror":"https://ror.org/006ae1882","country_code":"BG","type":"facility","lineage":["https://openalex.org/I24768866","https://openalex.org/I4210088296"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"H. Konstantinov","raw_affiliation_strings":["Scientific Research Centre of Specialty Polymers, Kl. Ohridski Str. 4A, 1756 Sofia, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Scientific Research Centre of Specialty Polymers, Kl. Ohridski Str. 4A, 1756 Sofia, Bulgaria","institution_ids":["https://openalex.org/I4210088296"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5041852146"],"corresponding_institution_ids":["https://openalex.org/I24768866"],"apc_list":{"value":4470,"currency":"USD","value_usd":4470},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"154","issue":"2","first_page":"205","last_page":"211"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":0.4984999895095825,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":0.4984999895095825,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.4884999990463257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10864","display_name":"Fluid Dynamics and Mixing","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/1507","display_name":"Fluid Flow and Transfer Processes"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aspartic-protease","display_name":"aspartic protease","score":0.890999972820282},{"id":"https://openalex.org/keywords/enzyme-immobilization","display_name":"enzyme immobilization","score":0.902999997138977},{"id":"https://openalex.org/keywords/fungal-enzyme-production","display_name":"fungal enzyme production","score":0.6639999747276306},{"id":"https://openalex.org/keywords/repeated-batch-fermentation","display_name":"repeated batch fermentation","score":0.9570000171661377},{"id":"https://openalex.org/keywords/airlift-bioreactor","display_name":"airlift bioreactor","score":0.9629999995231628},{"id":"https://openalex.org/keywords/semi-continuous-fermentation","display_name":"semi-continuous fermentation","score":0.7839999794960022},{"id":"https://openalex.org/keywords/proteolytic-activity","display_name":"proteolytic activity","score":0.7149999737739563}],"concepts":[{"id":"https://openalex.org/C168170006","wikidata":"https://www.wikidata.org/wiki/Q864699","display_name":"Bioreactor","level":2,"score":0.8551990985870361},{"id":"https://openalex.org/C2779498867","wikidata":"https://www.wikidata.org/wiki/Q2402182","display_name":"Prepolymer","level":3,"score":0.6595677137374878},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6593016982078552},{"id":"https://openalex.org/C133479454","wikidata":"https://www.wikidata.org/wiki/Q326228","display_name":"Mycelium","level":2,"score":0.6058527827262878},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.571216344833374},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.5594938397407532},{"id":"https://openalex.org/C139149728","wikidata":"https://www.wikidata.org/wiki/Q335201","display_name":"Laboratory flask","level":2,"score":0.5457574129104614},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5063544511795044},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.47317221760749817},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.43523216247558594},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.18594211339950562},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.07798734307289124},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C2779578285","wikidata":"https://www.wikidata.org/wiki/Q146322","display_name":"Polyurethane","level":2,"score":0.0},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0944-5013(99)80016-0","doi":"https://doi.org/10.1016/s0944-5013(99)80016-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0944-5013(99)80016-0","pdf_url":null,"source":{"id":"https://openalex.org/S106450229","display_name":"Microbiological Research","issn_l":"0944-5013","issn":["0944-5013","1618-0623"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiological Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W29039502","https://openalex.org/W318166512","https://openalex.org/W1966498100","https://openalex.org/W1970743622","https://openalex.org/W1986808796","https://openalex.org/W1993866822","https://openalex.org/W2016798382","https://openalex.org/W2030531199","https://openalex.org/W2049518682","https://openalex.org/W2055897133","https://openalex.org/W2057328771","https://openalex.org/W2071312110","https://openalex.org/W2071768679","https://openalex.org/W2074319974","https://openalex.org/W2078604072","https://openalex.org/W2098717965","https://openalex.org/W2114329602","https://openalex.org/W2136756532","https://openalex.org/W2137167171","https://openalex.org/W2317681030","https://openalex.org/W4232040579"],"related_works":["https://openalex.org/W2073062646","https://openalex.org/W1983327241","https://openalex.org/W2064708572","https://openalex.org/W4232040579","https://openalex.org/W2576178683","https://openalex.org/W2136756532","https://openalex.org/W2030531199","https://openalex.org/W2012993448","https://openalex.org/W2057328771","https://openalex.org/W1999659582"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}