{"id":"https://openalex.org/W2011109341","doi":"https://doi.org/10.1111/j.1601-183x.2011.00711.x","title":"Delayed procedural learning in \u03b17-nicotinic acetylcholine receptor knockout mice","display_name":"Delayed procedural learning in \u03b17-nicotinic acetylcholine receptor knockout mice","publication_year":2011,"publication_date":"2011-06-17","ids":{"openalex":"https://openalex.org/W2011109341","doi":"https://doi.org/10.1111/j.1601-183x.2011.00711.x","mag":"2011109341","pmid":"https://pubmed.ncbi.nlm.nih.gov/21679297"},"language":"en","primary_location":{"id":"doi:10.1111/j.1601-183x.2011.00711.x","doi":"https://doi.org/10.1111/j.1601-183x.2011.00711.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1601-183x.2011.00711.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1601-183X.2011.00711.x","source":{"id":"https://openalex.org/S134433296","display_name":"Genes Brain & Behavior","issn_l":"1601-183X","issn":["1601-183X","1601-1848"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes, Brain and Behavior","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1601-183X.2011.00711.x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028559117","display_name":"Jared W. Young","orcid":"https://orcid.org/0000-0003-3732-5776","observed_orcids":["https://orcid.org/0000-0003-3732-5776"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"J. W. Young","raw_affiliation_strings":["Department of Psychiatry, University of California San Diego, La Jolla, CA 92093-0804, USA. jaredyoung@ucsd.edu","Department of Psychiatry, University of California San Diego, La Jolla, CA 92093-0804, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of California San Diego, La Jolla, CA 92093-0804, USA. jaredyoung@ucsd.edu","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Department of Psychiatry, University of California San Diego, La Jolla, CA 92093-0804, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112873999","display_name":"Jessica M. Meves","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. M. Meves","raw_affiliation_strings":["Department of Psychiatry, University of California San Diego, La Jolla, CA, USA","Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of California San Diego, La Jolla, CA, USA","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016795436","display_name":"Isadore S. Tarantino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"I. S. Tarantino","raw_affiliation_strings":["Department of Psychiatry, University of California San Diego, La Jolla, CA, USA","Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of California San Diego, La Jolla, CA, USA","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048304313","display_name":"Sorana Caldwell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Caldwell","raw_affiliation_strings":["Department of Psychiatry, University of California San Diego, La Jolla, CA, USA","Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of California San Diego, La Jolla, CA, USA","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034576114","display_name":"Mark A. Geyer","orcid":"https://orcid.org/0000-0001-6137-9331","observed_orcids":["https://orcid.org/0000-0001-6137-9331"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. A. Geyer","raw_affiliation_strings":["Department of Psychiatry, University of California San Diego, La Jolla, CA, USA","Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of California San Diego, La Jolla, CA, USA","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA","institution_ids":["https://openalex.org/I36258959"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5028559117"],"corresponding_institution_ids":["https://openalex.org/I36258959"],"apc_list":{"value":3540,"currency":"USD","value_usd":3540},"apc_paid":null,"fwci":3.7602,"has_fulltext":true,"cited_by_count":92,"citation_normalized_percentile":{"value":0.94406621,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"10","issue":"7","first_page":"720","last_page":"733"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11818","display_name":"Nicotinic Acetylcholine Receptors Study","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11818","display_name":"Nicotinic Acetylcholine Receptors Study","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alpha7-nicotinic-acetylcholine-receptor","display_name":"alpha7 nicotinic acetylcholine receptor","score":0.9900000095367432},{"id":"https://openalex.org/keywords/knockout-mice","display_name":"knockout mice","score":0.8270000219345093},{"id":"https://openalex.org/keywords/procedural-learning","display_name":"procedural learning","score":0.9860000014305115},{"id":"https://openalex.org/keywords/rule-acquisition","display_name":"rule acquisition","score":0.828000009059906},{"id":"https://openalex.org/keywords/executive-function","display_name":"executive function","score":0.6119999885559082},{"id":"https://openalex.org/keywords/spatial-working-memory","display_name":"spatial working memory","score":0.7879999876022339},{"id":"https://openalex.org/keywords/short-term-memory","display_name":"short-term memory","score":0.9909999966621399},{"id":"https://openalex.org/keywords/reward-motivation","display_name":"reward motivation","score":0.8849999904632568},{"id":"https://openalex.org/keywords/prepulse-inhibition","display_name":"prepulse inhibition","score":0.7960000038146973},{"id":"https://openalex.org/keywords/sensorimotor-gating","display_name":"sensorimotor gating","score":0.9729999899864197},{"id":"https://openalex.org/keywords/attention","display_name":"attention","score":0.7379999756813049},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.7379999756813049},{"id":"https://openalex.org/keywords/cognitive-behavioral-therapy","display_name":"cognitive behavioral therapy","score":0.6980000138282776}],"concepts":[{"id":"https://openalex.org/C141421786","wikidata":"https://www.wikidata.org/wiki/Q1128897","display_name":"Prepulse inhibition","level":3,"score":0.7355732321739197},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6420378088951111},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6226634979248047},{"id":"https://openalex.org/C2779705967","wikidata":"https://www.wikidata.org/wiki/Q2271368","display_name":"Sensory gating","level":3,"score":0.6017903089523315},{"id":"https://openalex.org/C188987157","wikidata":"https://www.wikidata.org/wiki/Q7030581","display_name":"Nicotinic agonist","level":3,"score":0.5639594197273254},{"id":"https://openalex.org/C164749973","wikidata":"https://www.wikidata.org/wiki/Q18606","display_name":"Procedural memory","level":3,"score":0.5352194309234619},{"id":"https://openalex.org/C21963081","wikidata":"https://www.wikidata.org/wiki/Q11337567","display_name":"Working memory","level":3,"score":0.509149968624115},{"id":"https://openalex.org/C182704531","wikidata":"https://www.wikidata.org/wiki/Q1364740","display_name":"Knockout mouse","level":3,"score":0.49665218591690063},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.4950770437717438},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.4910542964935303},{"id":"https://openalex.org/C66102695","wikidata":"https://www.wikidata.org/wiki/Q5141208","display_name":"Cognitive flexibility","level":3,"score":0.4821155071258545},{"id":"https://openalex.org/C194544171","wikidata":"https://www.wikidata.org/wiki/Q21105679","display_name":"Gating","level":2,"score":0.44944998621940613},{"id":"https://openalex.org/C43729271","wikidata":"https://www.wikidata.org/wiki/Q3560550","display_name":"Spatial memory","level":4,"score":0.43444395065307617},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.42716100811958313},{"id":"https://openalex.org/C2775910092","wikidata":"https://www.wikidata.org/wiki/Q180623","display_name":"Acetylcholine","level":2,"score":0.4181234836578369},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.25576460361480713},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.1963043212890625},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18595397472381592},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.12268808484077454},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.07912713289260864}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001288","descriptor_name":"Attention","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001288","descriptor_name":"Attention","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001288","descriptor_name":"Attention","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005106","descriptor_name":"Exploratory Behavior","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005106","descriptor_name":"Exploratory Behavior","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005106","descriptor_name":"Exploratory Behavior","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008570","descriptor_name":"Memory, Short-Term","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008570","descriptor_name":"Memory, Short-Term","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008570","descriptor_name":"Memory, Short-Term","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009042","descriptor_name":"Motivation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009042","descriptor_name":"Motivation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009042","descriptor_name":"Motivation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011978","descriptor_name":"Receptors, Nicotinic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011978","descriptor_name":"Receptors, Nicotinic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011978","descriptor_name":"Receptors, Nicotinic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011978","descriptor_name":"Receptors, Nicotinic","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011978","descriptor_name":"Receptors, Nicotinic","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011978","descriptor_name":"Receptors, Nicotinic","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018782","descriptor_name":"Maze Learning","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018782","descriptor_name":"Maze Learning","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018782","descriptor_name":"Maze Learning","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D021641","descriptor_name":"Recognition, Psychology","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D021641","descriptor_name":"Recognition, Psychology","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D021641","descriptor_name":"Recognition, Psychology","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D046709","descriptor_name":"Pattern Recognition, Physiological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D046709","descriptor_name":"Pattern Recognition, Physiological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D046709","descriptor_name":"Pattern Recognition, Physiological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055139","descriptor_name":"Sensory Gating","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D055139","descriptor_name":"Sensory Gating","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D055139","descriptor_name":"Sensory Gating","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D056344","descriptor_name":"Executive Function","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D056344","descriptor_name":"Executive Function","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D056344","descriptor_name":"Executive Function","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D064569","descriptor_name":"alpha7 Nicotinic Acetylcholine Receptor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064569","descriptor_name":"alpha7 Nicotinic Acetylcholine Receptor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064569","descriptor_name":"alpha7 Nicotinic Acetylcholine Receptor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1111/j.1601-183x.2011.00711.x","doi":"https://doi.org/10.1111/j.1601-183x.2011.00711.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1601-183x.2011.00711.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1601-183X.2011.00711.x","source":{"id":"https://openalex.org/S134433296","display_name":"Genes Brain & Behavior","issn_l":"1601-183X","issn":["1601-183X","1601-1848"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes, Brain and Behavior","raw_type":"journal-article"},{"id":"pmid:21679297","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21679297","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes, brain, and behavior","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2902421","doi":null,"is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3918170","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3918170","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3918170","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Genes Brain Behav","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1111/j.1601-183x.2011.00711.x","doi":"https://doi.org/10.1111/j.1601-183x.2011.00711.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1601-183x.2011.00711.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1601-183X.2011.00711.x","source":{"id":"https://openalex.org/S134433296","display_name":"Genes Brain & Behavior","issn_l":"1601-183X","issn":["1601-183X","1601-1848"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes, Brain and Behavior","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.4099999964237213,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2231428184","display_name":null,"funder_award_id":"R21-MH085221","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G3873688245","display_name":"Studies with Nicotinic Null Mutant Mice","funder_award_id":"5p30da015663-10","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4847417790","display_name":"The rodent continuous performance task: Filling the vigilance translational gap","funder_award_id":"5r21mh085221-02","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G669421238","display_name":null,"funder_award_id":"P30-DA015663","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G672213889","display_name":null,"funder_award_id":"R01 MH071916","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320308970","display_name":"Teva Pharmaceutical Industries","ror":"https://ror.org/01wfv3m53"},{"id":"https://openalex.org/F4320319050","display_name":"Omeros Corporation","ror":"https://ror.org/01r5k6556"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"},{"id":"https://openalex.org/F4320337376","display_name":"NIH Clinical Center","ror":"https://ror.org/04vfsmv21"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2011109341.pdf","grobid_xml":"https://content.openalex.org/works/W2011109341.grobid-xml"},"referenced_works_count":93,"referenced_works":["https://openalex.org/W82501391","https://openalex.org/W1542611942","https://openalex.org/W1565658778","https://openalex.org/W1883094066","https://openalex.org/W1912293715","https://openalex.org/W1965198880","https://openalex.org/W1966224249","https://openalex.org/W1967132241","https://openalex.org/W1972981785","https://openalex.org/W1973217240","https://openalex.org/W1974151997","https://openalex.org/W1974559315","https://openalex.org/W1975400690","https://openalex.org/W1977494907","https://openalex.org/W1977517471","https://openalex.org/W1977583003","https://openalex.org/W1978614486","https://openalex.org/W1983664386","https://openalex.org/W1983746474","https://openalex.org/W1984173545","https://openalex.org/W1984465222","https://openalex.org/W1986240660","https://openalex.org/W1994437435","https://openalex.org/W1997749834","https://openalex.org/W2003290029","https://openalex.org/W2004753303","https://openalex.org/W2005044038","https://openalex.org/W2010375213","https://openalex.org/W2011867226","https://openalex.org/W2014453338","https://openalex.org/W2014707311","https://openalex.org/W2016488222","https://openalex.org/W2020025437","https://openalex.org/W2020326582","https://openalex.org/W2020765142","https://openalex.org/W2021654274","https://openalex.org/W2022838082","https://openalex.org/W2024262269","https://openalex.org/W2027885912","https://openalex.org/W2028127185","https://openalex.org/W2028452981","https://openalex.org/W2029743369","https://openalex.org/W2031964842","https://openalex.org/W2034183611","https://openalex.org/W2035818326","https://openalex.org/W2039714278","https://openalex.org/W2041781351","https://openalex.org/W2043935955","https://openalex.org/W2047396603","https://openalex.org/W2051256417","https://openalex.org/W2052167215","https://openalex.org/W2052942704","https://openalex.org/W2056271635","https://openalex.org/W2059495695","https://openalex.org/W2060400255","https://openalex.org/W2061785416","https://openalex.org/W2062363772","https://openalex.org/W2063140637","https://openalex.org/W2064085644","https://openalex.org/W2070740144","https://openalex.org/W2072117096","https://openalex.org/W2072194894","https://openalex.org/W2072994503","https://openalex.org/W2074915076","https://openalex.org/W2086901501","https://openalex.org/W2090470620","https://openalex.org/W2092635392","https://openalex.org/W2094767250","https://openalex.org/W2095613802","https://openalex.org/W2098736996","https://openalex.org/W2100527931","https://openalex.org/W2105454368","https://openalex.org/W2114226702","https://openalex.org/W2114853842","https://openalex.org/W2115821201","https://openalex.org/W2117093911","https://openalex.org/W2120431726","https://openalex.org/W2124533302","https://openalex.org/W2126463954","https://openalex.org/W2132675782","https://openalex.org/W2133883414","https://openalex.org/W2140474257","https://openalex.org/W2144671685","https://openalex.org/W2144848339","https://openalex.org/W2146638382","https://openalex.org/W2146710322","https://openalex.org/W2157622768","https://openalex.org/W2158052449","https://openalex.org/W2170557336","https://openalex.org/W2491937540","https://openalex.org/W4294856087","https://openalex.org/W4321347792","https://openalex.org/W4406057209"],"related_works":["https://openalex.org/W2052956331","https://openalex.org/W2148215007","https://openalex.org/W2223532918","https://openalex.org/W1974345292","https://openalex.org/W2041153769","https://openalex.org/W2068847058","https://openalex.org/W2071972527","https://openalex.org/W2396000083","https://openalex.org/W1993482722","https://openalex.org/W2385896683"],"abstract_inverted_index":{"The":[0,38,104,170],"\u03b17-nicotinic":[1],"acetylcholine":[2],"receptor":[3,21,179],"(nAChR)":[4],"has":[5,24,45],"long":[6],"been":[7,25,46,58],"a":[8,194],"procognitive":[9],"therapeutic":[10],"target":[11],"to":[12,31,60,167],"treat":[13],"schizophrenia.":[14],"Evidence":[15],"on":[16],"the":[17,32,65,77,84,96,113,122,129,175,189,201],"role":[18],"of":[19,35,40,68,81,89,101,107,221],"this":[20,178,209],"in":[22,28,76,149,188,206,218,227],"cognition":[23],"lacking,":[26],"however,":[27],"part":[29],"due":[30],"limited":[33,59],"availability":[34],"suitable":[36],"ligands.":[37],"behavior":[39,124],"\u03b17-nAChR":[41,69,137],"knockout":[42],"(KO)":[43],"mice":[44,75,139],"examined":[47,217],"previously,":[48],"but":[49,143],"cognitive":[50,66,230],"assessments":[51],"using":[52,112,128],"tests":[53],"with":[54,200,229],"cross-species":[55],"translatability":[56],"have":[57],"date.":[61],"Here,":[62],"we":[63,120],"assessed":[64,111,121],"performance":[67],"KO":[70,138],"and":[71,95,125,133,161,193,223],"wild-type":[72],"(WT)":[73],"littermate":[74],"attentional":[78],"set-shifting":[79],"task":[80],"executive":[82],"functioning,":[83],"radial":[85],"arm":[86],"maze":[87],"test":[88,100],"spatial":[90],"working":[91],"memory":[92],"span":[93,153],"capacity":[94],"novel":[97],"object":[98],"recognition":[99],"short-term":[102,155],"memory.":[103],"reward":[105],"motivation":[106,157],"these":[108,207],"mutants":[109],"was":[110],"progressive":[114],"ratio":[115],"breakpoint":[116],"test.":[117],"In":[118,198],"addition,":[119],"exploratory":[123],"sensorimotor":[126,162],"gating":[127,163],"behavioral":[130,231],"pattern":[131],"monitor":[132],"prepulse":[134],"inhibition,":[135],"respectively.":[136],"exhibited":[140],"normal":[141],"set-shifting,":[142],"impaired":[144,202],"procedural":[145,184,224],"learning":[146],"(rule":[147],"acquisition)":[148],"multiple":[150],"paradigms.":[151],"Spatial":[152],"capacity,":[154],"memory,":[156],"for":[158,182],"food,":[159],"exploration":[160],"were":[164],"all":[165],"comparable":[166],"WT":[168],"littermates.":[169],"data":[171],"presented":[172],"here":[173],"support":[174],"notion":[176],"that":[177,212],"is":[180,196],"important":[181],"such":[183],"learning,":[185,225],"when":[186],"patterns":[187],"environment":[190],"become":[191],"clear":[192],"rule":[195],"learned.":[197],"combination":[199,228],"attention":[203,222],"observed":[204],"previously":[205],"mice,":[208],"finding":[210],"suggests":[211],"agonist":[213],"treatments":[214],"should":[215],"be":[216],"clinical":[219],"studies":[220],"perhaps":[226],"therapy.":[232]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":13},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":9}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}