{"id":"https://openalex.org/W2011002894","doi":"https://doi.org/10.1097/01.mnm.0000171780.72908.e7","title":"Whole-body biodistribution, radiation dosimetry estimates for the PET norepinephrine transporter probe (S,S)-[18F]FMeNER-D2 in non-human primates","display_name":"Whole-body biodistribution, radiation dosimetry estimates for the PET norepinephrine transporter probe (S,S)-[18F]FMeNER-D2 in non-human primates","publication_year":2005,"publication_date":"2005-07-06","ids":{"openalex":"https://openalex.org/W2011002894","doi":"https://doi.org/10.1097/01.mnm.0000171780.72908.e7","mag":"2011002894","pmid":"https://pubmed.ncbi.nlm.nih.gov/16000987"},"language":"en","primary_location":{"id":"doi:10.1097/01.mnm.0000171780.72908.e7","doi":"https://doi.org/10.1097/01.mnm.0000171780.72908.e7","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.mnm.0000171780.72908.e7","pdf_url":null,"source":{"id":"https://openalex.org/S108023290","display_name":"Nuclear Medicine Communications","issn_l":"0143-3636","issn":["0143-3636","1473-5628"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nuclear Medicine Communications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001422614","display_name":"Nicholas M. Seneca","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Nicholas Seneca","raw_affiliation_strings":["Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden. Nick.Seneca@cns.ki.se","Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden. Nick.Seneca@cns.ki.se","institution_ids":["https://openalex.org/I1335113835","https://openalex.org/I28166907"]},{"raw_affiliation_string":"Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027058544","display_name":"Bengt Andr\u00e9e","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Bengt Andree","raw_affiliation_strings":["Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052118870","display_name":"Nils Sj\u00f6holm","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Nils Sjoholm","raw_affiliation_strings":["Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059935361","display_name":"Magnus Schou","orcid":"https://orcid.org/0000-0002-4314-2418","observed_orcids":["https://orcid.org/0000-0002-4314-2418"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Magnus Schou","raw_affiliation_strings":["Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden","Nicholas Seneca and Magnus Schou were supported by a grant from the NIH-KI joint PhD programme"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Nicholas Seneca and Magnus Schou were supported by a grant from the NIH-KI joint PhD programme","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111600214","display_name":"Stefan Pauli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Stefan Pauli","raw_affiliation_strings":["Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055445996","display_name":"P. David Mozley","orcid":"https://orcid.org/0000-0002-1651-4212","observed_orcids":["https://orcid.org/0000-0002-1651-4212"]},"institutions":[{"id":"https://openalex.org/I168537998","display_name":"Eli Lilly (United States)","ror":"https://ror.org/01qat3289","country_code":"US","type":"company","lineage":["https://openalex.org/I168537998"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. David Mozley","raw_affiliation_strings":["Eli Lilly Co., Indianapolis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eli Lilly Co., Indianapolis, USA","institution_ids":["https://openalex.org/I168537998"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078685289","display_name":"James B. Stubbs","orcid":"https://orcid.org/0000-0002-0885-5244","observed_orcids":["https://orcid.org/0000-0002-0885-5244"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"James B. Stubbs","raw_affiliation_strings":["Radiation Dosimetry Systems, Inc. Alpharetta, Georgia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiation Dosimetry Systems, Inc. Alpharetta, Georgia, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035586136","display_name":"Jeih\u2010San Liow","orcid":"https://orcid.org/0000-0002-7878-1076","observed_orcids":["https://orcid.org/0000-0002-7878-1076"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeih-San Liow","raw_affiliation_strings":["Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111956554","display_name":"Judit S\u00f3v\u00e1g\u00f3","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Judit Sovago","raw_affiliation_strings":["Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033422963","display_name":"Bal\u00e1zs Zolt\u00e1n Guly\u00e1s","orcid":"https://orcid.org/0000-0001-9295-2460","observed_orcids":["https://orcid.org/0000-0001-9295-2460"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Balazs Guly\u00e1s","raw_affiliation_strings":["Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079125204","display_name":"Robert B. Innis","orcid":"https://orcid.org/0000-0003-1238-7209","observed_orcids":["https://orcid.org/0000-0003-1238-7209"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Innis","raw_affiliation_strings":["Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081327813","display_name":"Christer Halldin","orcid":"https://orcid.org/0000-0002-7681-1104","observed_orcids":["https://orcid.org/0000-0002-7681-1104"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Christer Halldin","raw_affiliation_strings":["Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5001422614"],"corresponding_institution_ids":["https://openalex.org/I1335113835","https://openalex.org/I28166907"],"apc_list":null,"apc_paid":null,"fwci":3.3129,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.91151181,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"26","issue":"8","first_page":"695","last_page":"700"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9297000169754028,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9297000169754028,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.033799998462200165,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10844","display_name":"Radiation Dose and Imaging","score":0.025599999353289604,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/norepinephrine-transporter","display_name":"norepinephrine transporter","score":0.9670000076293945},{"id":"https://openalex.org/keywords/pet-radiotracer","display_name":"PET radiotracer","score":0.8259999752044678},{"id":"https://openalex.org/keywords/tissue-distribution","display_name":"tissue distribution","score":0.949999988079071},{"id":"https://openalex.org/keywords/radiation-dosimetry","display_name":"radiation dosimetry","score":0.9459999799728394},{"id":"https://openalex.org/keywords/effective-dose","display_name":"effective dose","score":0.7310000061988831},{"id":"https://openalex.org/keywords/cynomolgus-monkeys","display_name":"Macaca fascicularis","score":0.8199999928474426},{"id":"https://openalex.org/keywords/bladder","display_name":"urinary bladder","score":0.7149999737739563},{"id":"https://openalex.org/keywords/kidney","display_name":"kidney","score":0.47600001096725464},{"id":"https://openalex.org/keywords/lung","display_name":"lung","score":0.6779999732971191},{"id":"https://openalex.org/keywords/heart","display_name":"heart","score":0.5899999737739563},{"id":"https://openalex.org/keywords/red-bone-marrow","display_name":"red bone marrow","score":0.7599999904632568}],"concepts":[{"id":"https://openalex.org/C2777807558","wikidata":"https://www.wikidata.org/wiki/Q4914764","display_name":"Biodistribution","level":3,"score":0.764882504940033},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.6698182225227356},{"id":"https://openalex.org/C67847695","wikidata":"https://www.wikidata.org/wiki/Q626478","display_name":"Radioligand","level":3,"score":0.6225505471229553},{"id":"https://openalex.org/C75088862","wikidata":"https://www.wikidata.org/wiki/Q2291081","display_name":"Dosimetry","level":2,"score":0.622134268283844},{"id":"https://openalex.org/C2779762690","wikidata":"https://www.wikidata.org/wiki/Q9382","display_name":"Urinary bladder","level":2,"score":0.499037504196167},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.4668978154659271},{"id":"https://openalex.org/C176233148","wikidata":"https://www.wikidata.org/wiki/Q14874257","display_name":"Norepinephrine transporter","level":4,"score":0.45785224437713623},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4437936842441559},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.403033047914505},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3952484130859375},{"id":"https://openalex.org/C2778514916","wikidata":"https://www.wikidata.org/wiki/Q186242","display_name":"Norepinephrine","level":3,"score":0.288798987865448},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2243819236755371},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21591416001319885},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11020159721374512},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001822","descriptor_name":"Body Burden","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007275","descriptor_name":"Injections, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008252","descriptor_name":"Macaca fascicularis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008657","descriptor_name":"Metabolic Clearance Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009025","descriptor_name":"Morpholines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D009025","descriptor_name":"Morpholines","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D009928","descriptor_name":"Organ Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011829","descriptor_name":"Radiation Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011874","descriptor_name":"Radiometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D012062","descriptor_name":"Relative Biological Effectiveness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014018","descriptor_name":"Tissue Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014915","descriptor_name":"Whole-Body Counting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015336","descriptor_name":"Molecular Probe Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019275","descriptor_name":"Radiopharmaceuticals","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D019275","descriptor_name":"Radiopharmaceuticals","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/01.mnm.0000171780.72908.e7","doi":"https://doi.org/10.1097/01.mnm.0000171780.72908.e7","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.mnm.0000171780.72908.e7","pdf_url":null,"source":{"id":"https://openalex.org/S108023290","display_name":"Nuclear Medicine Communications","issn_l":"0143-3636","issn":["0143-3636","1473-5628"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nuclear Medicine Communications","raw_type":"journal-article"},{"id":"pmid:16000987","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16000987","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nuclear medicine communications","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307758","display_name":"Eli Lilly and Company","ror":"https://ror.org/01qat3289"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W81520806","https://openalex.org/W366950334","https://openalex.org/W1588260775","https://openalex.org/W1934549153","https://openalex.org/W1968142570","https://openalex.org/W1984335013","https://openalex.org/W1986968200","https://openalex.org/W1987262076","https://openalex.org/W1999005298","https://openalex.org/W2001108200","https://openalex.org/W2015456341","https://openalex.org/W2018190562","https://openalex.org/W2018698014","https://openalex.org/W2037927415","https://openalex.org/W2042703635","https://openalex.org/W2049702924","https://openalex.org/W2086851841","https://openalex.org/W2121414226","https://openalex.org/W2150540840","https://openalex.org/W2155197623","https://openalex.org/W2162171408","https://openalex.org/W2164598823","https://openalex.org/W2165211592","https://openalex.org/W2215396592","https://openalex.org/W6640349222","https://openalex.org/W6688407050"],"related_works":["https://openalex.org/W70274129","https://openalex.org/W2086851841","https://openalex.org/W7904472","https://openalex.org/W2892739081","https://openalex.org/W1988503950","https://openalex.org/W2052128998","https://openalex.org/W2083157399","https://openalex.org/W2202807698","https://openalex.org/W2741846759","https://openalex.org/W2084161441"],"abstract_inverted_index":{"BACKGROUND:":[0],"(S,S)-[F]FMeNER-D2":[1,253],"is":[2,10,254],"a":[3,11,126,183,231],"recently":[4],"developed":[5],"norepinephrine":[6,21],"transporter":[7,22],"ligand":[8],"which":[9],"potentially":[12],"useful":[13],"radiotracer":[14],"for":[15,51,59,133],"mapping":[16],"the":[17,34,79,89,97,104,120,134,190],"brain":[18,148],"and":[19,38,107,174,215,226,236],"heart":[20,168,208],"in":[23,55,196],"vivo":[24],"using":[25,96],"positron":[26],"emission":[27],"tomography.":[28],"In":[29,114],"this":[30],"work,":[31],"we":[32],"quantified":[33],"biodistribution":[35],"over":[36],"time":[37,53,85,127],"radiation":[39,81,93,250],"exposure":[40,82],"to":[41,69,75,237,256],"multiple":[42],"organs":[43,77,192],"with":[44,78,103,193,225],"(S,S)-[F]FMeNER-D2.":[45],"METHODS:":[46],"Whole-body":[47],"images":[48,72],"were":[49,73,94,131,204,223],"acquired":[50],"21":[52],"points":[54],"two":[56],"cynomolgus":[57],"monkeys":[58],"approximately":[60],"270":[61],"min":[62],"after":[63,128],"injection":[64,130],"of":[65,88,92,119,187,233,252,258],"radioligand.":[66],"Compressed":[67],"3-D":[68],"2-D":[70],"planar":[71,115],"used":[74],"identify":[76],"highest":[80,194],"at":[83,125,138,144,151,157,165,171,179,230],"each":[84],"point.":[86],"Estimates":[87],"absorbed":[90],"dose":[91,123],"calculated":[95,132],"MIRDOSE":[98],"3.1":[99],"software":[100],"program":[101],"performed":[102],"dynamic":[105],"bladder":[106,176,217],"ICRP":[108],"30":[109],"gastrointestinal":[110],"tract":[111],"models.":[112],"RESULTS:":[113],"images,":[116],"peak":[117],"values":[118],"percent":[121],"injected":[122],"(%ID)":[124],"radioligand":[129],"lungs":[135,212],"(26.76%":[136],"ID":[137,143,150,156,164,170,178],"1.42":[139,172],"min),":[140,146,153,159,167],"kidneys":[141,205],"(13.55%":[142],"2.18":[145],"whole":[147],"(5.65%":[149],"4.48":[152],"liver":[154],"(7.20%":[155],"2":[158],"red":[160],"bone":[161],"marrow":[162],"(5.02%":[163],"2.06":[166],"(2.36%":[169],"min)":[173],"urinary":[175,216],"(23%":[177],"250":[180],"min).":[181],"Assuming":[182],"urine":[184,228],"voiding":[185,229],"interval":[186],"2.4":[188],"h,":[189],"four":[191],"exposures":[195],"microGy":[197,240],".":[198,202,241,245],"MBq":[199,242],"(":[200,243],"mrad":[201,244],"mCi)":[203],"126":[206],"(468),":[207],"wall":[209],"108":[210],"(399),":[211],"88.4":[213],"(327)":[214],"114":[218],"(422).":[219],"The":[220,248],"effective":[221],"doses":[222],"estimated":[224,249],"without":[227],"range":[232],"123":[234],"(33)":[235],"131":[238],"(35.5)":[239],"mCi).":[246],"CONCLUSION:":[247],"burden":[251],"comparable":[255],"that":[257],"other":[259],"F":[260],"radioligands.":[261]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}