{"id":"https://openalex.org/W2010999937","doi":"https://doi.org/10.1002/jbmr.135","title":"Sclerostin antibody treatment enhances metaphyseal bone healing in rats","display_name":"Sclerostin antibody treatment enhances metaphyseal bone healing in rats","publication_year":2010,"publication_date":"2010-05-17","ids":{"openalex":"https://openalex.org/W2010999937","doi":"https://doi.org/10.1002/jbmr.135","mag":"2010999937","pmid":"https://pubmed.ncbi.nlm.nih.gov/20499342"},"language":"en","primary_location":{"id":"doi:10.1002/jbmr.135","doi":"https://doi.org/10.1002/jbmr.135","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jbmr.135","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jbmr.135","source":{"id":"https://openalex.org/S128199769","display_name":"Journal of Bone and Mineral Research","issn_l":"0884-0431","issn":["0884-0431","1523-4681"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bone and Mineral Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jbmr.135","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045131956","display_name":"Fredrik Agholme","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102134673","display_name":"Link\u00f6ping University","ror":"https://ror.org/05ynxx418","country_code":"SE","type":"education","lineage":["https://openalex.org/I102134673"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Fredrik Agholme","raw_affiliation_strings":["Orthopedics, Department of Clinical and Experimental Medicine, Faculty of Medicine, Link\u00f6ping University, Link\u00f6ping, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopedics, Department of Clinical and Experimental Medicine, Faculty of Medicine, Link\u00f6ping University, Link\u00f6ping, Sweden","institution_ids":["https://openalex.org/I102134673"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100369698","display_name":"Xiaodong Li","orcid":"https://orcid.org/0000-0002-2089-5046","observed_orcids":["https://orcid.org/0000-0002-2089-5046","https://orcid.org/0000-0002-0608-8192"]},"institutions":[{"id":"https://openalex.org/I1320553840","display_name":"Amgen (United States)","ror":"https://ror.org/03g03ge92","country_code":"US","type":"company","lineage":["https://openalex.org/I1320553840"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaodong Li","raw_affiliation_strings":["Metabolic Disorders, Amgen, Inc., Thousand Oaks, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Metabolic Disorders, Amgen, Inc., Thousand Oaks, CA, USA","institution_ids":["https://openalex.org/I1320553840"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074735538","display_name":"Hanna Isaksson","orcid":"https://orcid.org/0000-0002-9690-8907","observed_orcids":["https://orcid.org/0000-0002-9690-8907"]},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Hanna Isaksson","raw_affiliation_strings":["Department of Physics and Mathematics, University of Eastern Finland, Kuopio, Finland","Department of Physics and Mathematics, University of Eastern Finland, Kuopio, Finland#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics and Mathematics, University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]},{"raw_affiliation_string":"Department of Physics and Mathematics, University of Eastern Finland, Kuopio, Finland#TAB#","institution_ids":["https://openalex.org/I175532246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103171015","display_name":"Hua Zhu Ke","orcid":"https://orcid.org/0000-0003-2883-9134","observed_orcids":["https://orcid.org/0000-0003-2883-9134"]},"institutions":[{"id":"https://openalex.org/I1320553840","display_name":"Amgen (United States)","ror":"https://ror.org/03g03ge92","country_code":"US","type":"company","lineage":["https://openalex.org/I1320553840"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hua Zhu Ke","raw_affiliation_strings":["Metabolic Disorders, Amgen, Inc., Thousand Oaks, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Metabolic Disorders, Amgen, Inc., Thousand Oaks, CA, USA","institution_ids":["https://openalex.org/I1320553840"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014258435","display_name":"Per Aspenberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102134673","display_name":"Link\u00f6ping University","ror":"https://ror.org/05ynxx418","country_code":"SE","type":"education","lineage":["https://openalex.org/I102134673"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Per Aspenberg","raw_affiliation_strings":["Orthopedics, Department of Clinical and Experimental Medicine, Faculty of Medicine, Link\u00f6ping University, Link\u00f6ping, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopedics, Department of Clinical and Experimental Medicine, Faculty of Medicine, Link\u00f6ping University, Link\u00f6ping, Sweden","institution_ids":["https://openalex.org/I102134673"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5045131956"],"corresponding_institution_ids":["https://openalex.org/I102134673"],"apc_list":{"value":3780,"currency":"USD","value_usd":3780},"apc_paid":null,"fwci":19.3549,"has_fulltext":true,"cited_by_count":148,"citation_normalized_percentile":{"value":0.9966649,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"25","issue":"11","first_page":"2412","last_page":"2418"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9452999830245972,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9452999830245972,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.03200000151991844,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10658","display_name":"Bone fractures and treatments","score":0.006099999882280827,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sclerostin","display_name":"sclerostin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/sost-gene","display_name":"SOST gene","score":0.7559999823570251},{"id":"https://openalex.org/keywords/bone-regeneration","display_name":"bone regeneration","score":0.6269999742507935},{"id":"https://openalex.org/keywords/screw-pullout-strength","display_name":"screw pullout strength","score":0.7089999914169312},{"id":"https://openalex.org/keywords/bone-formation","display_name":"bone formation","score":0.7080000042915344},{"id":"https://openalex.org/keywords/trabecular-bone","display_name":"trabecular bone","score":0.6589999794960022},{"id":"https://openalex.org/keywords/wnt-signaling","display_name":"Wnt signaling","score":0.8870000243186951},{"id":"https://openalex.org/keywords/osteocytes","display_name":"osteocytes","score":0.8830000162124634},{"id":"https://openalex.org/keywords/tibia","display_name":"tibia","score":0.39399999380111694}],"concepts":[{"id":"https://openalex.org/C2779277721","wikidata":"https://www.wikidata.org/wiki/Q14887295","display_name":"Sclerostin","level":4,"score":0.9944685697555542},{"id":"https://openalex.org/C2776350087","wikidata":"https://www.wikidata.org/wiki/Q265868","display_name":"Cancellous bone","level":2,"score":0.6399151682853699},{"id":"https://openalex.org/C2777236700","wikidata":"https://www.wikidata.org/wiki/Q178366","display_name":"Tibia","level":2,"score":0.6105491518974304},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5778676271438599},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5737684369087219},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5539714097976685},{"id":"https://openalex.org/C2776886416","wikidata":"https://www.wikidata.org/wiki/Q4941567","display_name":"Bone mineral","level":3,"score":0.5482006669044495},{"id":"https://openalex.org/C8337478","wikidata":"https://www.wikidata.org/wiki/Q1777289","display_name":"Bone healing","level":2,"score":0.5085409879684448},{"id":"https://openalex.org/C2780707029","wikidata":"https://www.wikidata.org/wiki/Q1512017","display_name":"Long bone","level":2,"score":0.4294532239437103},{"id":"https://openalex.org/C31507581","wikidata":"https://www.wikidata.org/wiki/Q425383","display_name":"Bone morphogenetic protein","level":3,"score":0.41095203161239624},{"id":"https://openalex.org/C137620995","wikidata":"https://www.wikidata.org/wiki/Q155769","display_name":"Wnt signaling pathway","level":3,"score":0.3901154696941376},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.30977869033813477},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2444477081298828},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.22281917929649353},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.08820044994354248},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001696","descriptor_name":"Biomechanical Phenomena","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001863","descriptor_name":"Bone Screws","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005819","descriptor_name":"Genetic Markers","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008903","descriptor_name":"Minerals","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009929","descriptor_name":"Organ Size","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013977","descriptor_name":"Tibia","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D013977","descriptor_name":"Tibia","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013977","descriptor_name":"Tibia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D015519","descriptor_name":"Bone Density","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019485","descriptor_name":"Bone Morphogenetic Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055114","descriptor_name":"X-Ray Microtomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057134","descriptor_name":"Antibodies, Neutralizing","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D057134","descriptor_name":"Antibodies, Neutralizing","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1002/jbmr.135","doi":"https://doi.org/10.1002/jbmr.135","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jbmr.135","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jbmr.135","source":{"id":"https://openalex.org/S128199769","display_name":"Journal of Bone and Mineral Research","issn_l":"0884-0431","issn":["0884-0431","1523-4681"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bone and Mineral Research","raw_type":"journal-article"},{"id":"pmid:20499342","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20499342","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research","raw_type":"Journal Article"},{"id":"pmh:oai:lup.lub.lu.se:76fc6f90-e2a2-4e94-818a-819c62e60401","doi":null,"is_oa":false,"landing_page_url":"https://lup.lub.lu.se/record/2277193","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Bone and Mineral Research; 25(11), pp 2412-2418 (2010)","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1002/jbmr.135","doi":"https://doi.org/10.1002/jbmr.135","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jbmr.135","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jbmr.135","source":{"id":"https://openalex.org/S128199769","display_name":"Journal of Bone and Mineral Research","issn_l":"0884-0431","issn":["0884-0431","1523-4681"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bone and Mineral Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307105","display_name":"Amgen","ror":"https://ror.org/03g03ge92"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2010999937.pdf","grobid_xml":"https://content.openalex.org/works/W2010999937.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W1966994557","https://openalex.org/W1970708343","https://openalex.org/W1983220846","https://openalex.org/W2011823975","https://openalex.org/W2029179236","https://openalex.org/W2029614230","https://openalex.org/W2031897899","https://openalex.org/W2037750372","https://openalex.org/W2041130002","https://openalex.org/W2043991983","https://openalex.org/W2055746941","https://openalex.org/W2068916684","https://openalex.org/W2072100512","https://openalex.org/W2091514824","https://openalex.org/W2108700015","https://openalex.org/W2119934014","https://openalex.org/W2134478449","https://openalex.org/W2135671879","https://openalex.org/W2149719379","https://openalex.org/W2167572811","https://openalex.org/W6658613307"],"related_works":["https://openalex.org/W2165472165","https://openalex.org/W2147248281","https://openalex.org/W2161437947","https://openalex.org/W2002199938","https://openalex.org/W2799683212","https://openalex.org/W2175678752","https://openalex.org/W2751358838","https://openalex.org/W1533291475","https://openalex.org/W2341156823","https://openalex.org/W2030181973"],"abstract_inverted_index":{"Sclerostin":[0,136],"is":[1,22,36],"the":[2,5,11,40,65,81,110,118,129,140,155,159,171,177,192,210,218],"product":[3],"of":[4,26,59,67,93,120,161,170,212],"SOST":[6,12],"gene.":[7],"Loss-of-function":[8],"mutations":[9],"in":[10,15,33,71,80,128,184,188,200,203,229],"gene":[13],"result":[14],"a":[16,23,60,77,99,122,181,189,197],"high-bone-mass":[17],"phenotype,":[18],"demonstrating":[19],"that":[20,176],"sclerostin":[21,35,94,219],"negative":[24],"regulator":[25],"bone":[27,51,70,185,213,222],"mass.":[28],"Primarily":[29],"expressed":[30],"by":[31,143,209],"osteocytes":[32],"bone,":[34],"reported":[37],"to":[38,180],"bind":[39],"LRP5/6":[41],"receptor,":[42],"thereby":[43],"antagonizing":[44],"canonical":[45],"Wnt":[46],"signaling":[47],"and":[48,84,132,151,214],"negatively":[49],"regulating":[50],"formation.":[52],"We":[53],"therefore":[54],"investigated":[55],"whether":[56],"systemic":[57],"administration":[58],"sclerostin-neutralizing":[61],"antibody":[62,95,137,178,220],"would":[63],"increase":[64,183,199],"regeneration":[66],"traumatized":[68],"metaphyseal":[69,225],"rats.":[72],"Young":[73],"male":[74],"rats":[75],"had":[76],"screw":[78,124],"inserted":[79,127,157],"proximal":[82],"tibia":[83,131],"were":[85,112],"divided":[86],"into":[87],"six":[88],"groups":[89,174],"given":[90],"25":[91],"mg/kg":[92],"or":[96,104],"control":[97],"twice":[98],"week":[100],"subcutaneously":[101],"for":[102,114],"2":[103,150],"4":[105,152],"weeks.":[106,153],"In":[107],"four":[108],"groups,":[109],"screws":[111,156],"tested":[113,134],"pull-out":[115,133,141,165],"strength.":[116],"At":[117],"time":[119,160],"euthanasia,":[121],"similar":[123],"also":[125,195,228],"was":[126,196],"contralateral":[130],"immediately.":[135],"significantly":[138],"increased":[139,164,221],"force":[142],"almost":[144],"50%":[145],"compared":[146],"with":[147],"controls":[148],"after":[149],"Also,":[154],"at":[158],"euthanasia":[162],"showed":[163,175],"force.":[166],"Micro-computed":[167],"tomography":[168],"(\u00b5CT)":[169],"remaining":[172],"two":[173],"led":[179],"30%":[182],"volume":[186],"fraction":[187],"region":[190],"surrounding":[191],"screw.":[193],"There":[194],"general":[198],"trabecular":[201],"thickness":[202],"cancellous":[204],"bone.":[205,231],"Thus,":[206],"as":[207],"measured":[208],"amount":[211],"its":[215],"mechanical":[216],"resistance,":[217],"formation":[223],"during":[224],"repair":[226],"but":[227],"untraumatized":[230]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":15},{"year":2014,"cited_by_count":19},{"year":2013,"cited_by_count":19},{"year":2012,"cited_by_count":21}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}