{"id":"https://openalex.org/W2010866322","doi":"https://doi.org/10.1016/s0893-133x(98)00077-3","title":"Pituitary-Adrenal Cortical Responses to Low-Dose Physostigmine and Arginine Vasopressin Administration in Normal Women and Men","display_name":"Pituitary-Adrenal Cortical Responses to Low-Dose Physostigmine and Arginine Vasopressin Administration in Normal Women and Men","publication_year":1999,"publication_date":"1999-05-01","ids":{"openalex":"https://openalex.org/W2010866322","doi":"https://doi.org/10.1016/s0893-133x(98)00077-3","mag":"2010866322","pmid":"https://pubmed.ncbi.nlm.nih.gov/10192824"},"language":"en","primary_location":{"id":"doi:10.1016/s0893-133x(98)00077-3","doi":"https://doi.org/10.1016/s0893-133x(98)00077-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0893-133x(98)00077-3","pdf_url":null,"source":{"id":"https://openalex.org/S175030738","display_name":"Neuropsychopharmacology","issn_l":"0893-133X","issn":["0893-133X","1740-634X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuropsychopharmacology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004369157","display_name":"Robert T. Rub\u00edn","orcid":"https://orcid.org/0000-0002-0304-4303","observed_orcids":["https://orcid.org/0000-0002-0304-4303"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"R Rubin","raw_affiliation_strings":["Center for Neurosciences Research, MCP Hahnemann School of Medicine, Allegheny University of the Health Sciences, Pittsburgh, Pennsylvania 15212-4772, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neurosciences Research, MCP Hahnemann School of Medicine, Allegheny University of the Health Sciences, Pittsburgh, Pennsylvania 15212-4772, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5004369157"],"corresponding_institution_ids":[],"apc_list":{"value":5290,"currency":"USD","value_usd":5290},"apc_paid":null,"fwci":1.2428,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.73762376,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"20","issue":"5","first_page":"434","last_page":"446"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.007899999618530273,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypothalamic-pituitary-adrenal-axis","display_name":"hypothalamic-pituitary-adrenal axis","score":0.921999990940094},{"id":"https://openalex.org/keywords/physostigmine","display_name":"physostigmine","score":0.9860000014305115},{"id":"https://openalex.org/keywords/vasopressin","display_name":"vasopressin","score":0.9829999804496765},{"id":"https://openalex.org/keywords/acth","display_name":"ACTH","score":0.6930000185966492},{"id":"https://openalex.org/keywords/cortisol","display_name":"cortisol","score":0.996999979019165},{"id":"https://openalex.org/keywords/cholinergic-transmission","display_name":"cholinergic neurotransmission","score":0.8600000143051147},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8610000014305115},{"id":"https://openalex.org/keywords/cholinesterase-inhibitors","display_name":"cholinesterase inhibitors","score":0.6880000233650208},{"id":"https://openalex.org/keywords/stress-response","display_name":"stress response","score":0.5199999809265137},{"id":"https://openalex.org/keywords/adverse-effects","display_name":"adverse effects","score":0.550000011920929},{"id":"https://openalex.org/keywords/central-cholinergic-system","display_name":"central cholinergic system","score":0.6539999842643738}],"concepts":[{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8508313894271851},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8466572165489197},{"id":"https://openalex.org/C2776370428","wikidata":"https://www.wikidata.org/wiki/Q21124841","display_name":"Vasopressin","level":2,"score":0.8232766389846802},{"id":"https://openalex.org/C2776663719","wikidata":"https://www.wikidata.org/wiki/Q410595","display_name":"Physostigmine","level":3,"score":0.741558313369751},{"id":"https://openalex.org/C2777468819","wikidata":"https://www.wikidata.org/wiki/Q173670","display_name":"Arginine","level":3,"score":0.5799594521522522},{"id":"https://openalex.org/C22885893","wikidata":"https://www.wikidata.org/wiki/Q4862743","display_name":"Cholinergic","level":2,"score":0.49505987763404846},{"id":"https://openalex.org/C2778709874","wikidata":"https://www.wikidata.org/wiki/Q190875","display_name":"Hydrocortisone","level":2,"score":0.48821523785591125},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.482778936624527},{"id":"https://openalex.org/C2776176026","wikidata":"https://www.wikidata.org/wiki/Q169960","display_name":"Oxytocin","level":2,"score":0.45056337118148804},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.41125404834747314},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.13655942678451538},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000324","descriptor_name":"Adrenocorticotropic Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001127","descriptor_name":"Arginine Vasopressin","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D001127","descriptor_name":"Arginine Vasopressin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D003346","descriptor_name":"Corticotropin-Releasing Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006854","descriptor_name":"Hydrocortisone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010277","descriptor_name":"Parasympathomimetics","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D010277","descriptor_name":"Parasympathomimetics","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010830","descriptor_name":"Physostigmine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D010830","descriptor_name":"Physostigmine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010913","descriptor_name":"Pituitary-Adrenal System","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D011569","descriptor_name":"Psychiatric Status Rating Scales","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019540","descriptor_name":"Area Under Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0893-133x(98)00077-3","doi":"https://doi.org/10.1016/s0893-133x(98)00077-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0893-133x(98)00077-3","pdf_url":null,"source":{"id":"https://openalex.org/S175030738","display_name":"Neuropsychopharmacology","issn_l":"0893-133X","issn":["0893-133X","1740-634X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuropsychopharmacology","raw_type":"journal-article"},{"id":"pmid:10192824","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10192824","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1127768959","display_name":"Hormone Rhythms: Metabolic Significance in Depression","funder_award_id":"R01MH028380","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G1483128446","display_name":"HORMONE RHYTHMS: METABOLIC SIGNIFICANCE IN PSYCHIATRY","funder_award_id":"5k05mh047363-14","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G410706555","display_name":null,"funder_award_id":"MH28380","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G521520193","display_name":null,"funder_award_id":"MH 47363","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":63,"referenced_works":["https://openalex.org/W45982646","https://openalex.org/W174214648","https://openalex.org/W342927051","https://openalex.org/W1002564877","https://openalex.org/W1554082852","https://openalex.org/W1780720469","https://openalex.org/W1963971520","https://openalex.org/W1972356004","https://openalex.org/W1980243809","https://openalex.org/W1983234665","https://openalex.org/W1985944381","https://openalex.org/W1992463008","https://openalex.org/W1995226963","https://openalex.org/W1996832515","https://openalex.org/W1996925165","https://openalex.org/W2002778337","https://openalex.org/W2004214768","https://openalex.org/W2005257361","https://openalex.org/W2006770638","https://openalex.org/W2010185930","https://openalex.org/W2014619876","https://openalex.org/W2018104754","https://openalex.org/W2027002868","https://openalex.org/W2027680233","https://openalex.org/W2031839815","https://openalex.org/W2034712034","https://openalex.org/W2047373651","https://openalex.org/W2051312687","https://openalex.org/W2052866961","https://openalex.org/W2053252692","https://openalex.org/W2055510865","https://openalex.org/W2056270105","https://openalex.org/W2058509253","https://openalex.org/W2061378977","https://openalex.org/W2065053827","https://openalex.org/W2066859150","https://openalex.org/W2069134310","https://openalex.org/W2071698030","https://openalex.org/W2072650176","https://openalex.org/W2073652139","https://openalex.org/W2082279174","https://openalex.org/W2089154287","https://openalex.org/W2095491277","https://openalex.org/W2095831393","https://openalex.org/W2101036608","https://openalex.org/W2103417035","https://openalex.org/W2104111400","https://openalex.org/W2104308931","https://openalex.org/W2105453573","https://openalex.org/W2105951111","https://openalex.org/W2108131643","https://openalex.org/W2135907210","https://openalex.org/W2141707341","https://openalex.org/W2147303576","https://openalex.org/W2155322333","https://openalex.org/W2159011576","https://openalex.org/W2159078759","https://openalex.org/W2403665100","https://openalex.org/W2467119292","https://openalex.org/W2606490559","https://openalex.org/W2981480949","https://openalex.org/W4236143111","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2080602283","https://openalex.org/W2084590270","https://openalex.org/W2118563763","https://openalex.org/W2093524099","https://openalex.org/W1983234665","https://openalex.org/W1963971520","https://openalex.org/W2052866961","https://openalex.org/W1985944381","https://openalex.org/W2003961298","https://openalex.org/W2051074265"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
