{"id":"https://openalex.org/W2010823014","doi":"https://doi.org/10.3892/ol.2014.1918","title":"Inhibition of urokinase-type plasminogen activator expression by dihydroartemisinin in breast cancer cells","display_name":"Inhibition of urokinase-type plasminogen activator expression by dihydroartemisinin in breast cancer cells","publication_year":2014,"publication_date":"2014-02-27","ids":{"openalex":"https://openalex.org/W2010823014","doi":"https://doi.org/10.3892/ol.2014.1918","mag":"2010823014","pmid":"https://pubmed.ncbi.nlm.nih.gov/24765140","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3997666"},"language":"en","primary_location":{"id":"doi:10.3892/ol.2014.1918","doi":"https://doi.org/10.3892/ol.2014.1918","is_oa":true,"landing_page_url":"https://doi.org/10.3892/ol.2014.1918","pdf_url":"https://www.spandidos-publications.com/10.3892/ol.2014.1918/download","source":{"id":"https://openalex.org/S58832373","display_name":"Oncology Letters","issn_l":"1792-1074","issn":["1792-1074","1792-1082"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.spandidos-publications.com/10.3892/ol.2014.1918/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075116238","display_name":"Shuqun Zhang","orcid":"https://orcid.org/0000-0003-2959-6461","observed_orcids":["https://orcid.org/0000-0003-2959-6461","https://orcid.org/0000-0002-6998-7849"]},"institutions":[{"id":"https://openalex.org/I4210131893","display_name":"Second Affiliated Hospital of Xi'an Jiaotong University","ror":"https://ror.org/03aq7kf18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131893"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"SHUQUN ZHANG","raw_affiliation_strings":["Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China","institution_ids":["https://openalex.org/I4210131893"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087550082","display_name":"Yinan Ma","orcid":"https://orcid.org/0009-0002-2354-5591","observed_orcids":["https://orcid.org/0009-0002-2354-5591"]},"institutions":[{"id":"https://openalex.org/I4210131893","display_name":"Second Affiliated Hospital of Xi'an Jiaotong University","ror":"https://ror.org/03aq7kf18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131893"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"YINAN MA","raw_affiliation_strings":["Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China","institution_ids":["https://openalex.org/I4210131893"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113762919","display_name":"Jiantao Jiang","orcid":"https://orcid.org/0009-0004-4396-1749","observed_orcids":["https://orcid.org/0009-0004-4396-1749"]},"institutions":[{"id":"https://openalex.org/I4210131893","display_name":"Second Affiliated Hospital of Xi'an Jiaotong University","ror":"https://ror.org/03aq7kf18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131893"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"JIANTAO JIANG","raw_affiliation_strings":["Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China","institution_ids":["https://openalex.org/I4210131893"]}]},{"author_position":"middle","author":{"id":null,"display_name":"ZHIJUN DAI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210131893","display_name":"Second Affiliated Hospital of Xi'an Jiaotong University","ror":"https://ror.org/03aq7kf18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131893"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"ZHIJUN DAI","raw_affiliation_strings":["Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China","institution_ids":["https://openalex.org/I4210131893"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080683482","display_name":"Xiaoyan Gao","orcid":"https://orcid.org/0000-0002-1656-2740","observed_orcids":["https://orcid.org/0000-0002-1656-2740"]},"institutions":[{"id":"https://openalex.org/I4210131893","display_name":"Second Affiliated Hospital of Xi'an Jiaotong University","ror":"https://ror.org/03aq7kf18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131893"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"XIAOYAN GAO","raw_affiliation_strings":["Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China","institution_ids":["https://openalex.org/I4210131893"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102077295","display_name":"Xiaoran Yin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210131893","display_name":"Second Affiliated Hospital of Xi'an Jiaotong University","ror":"https://ror.org/03aq7kf18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131893"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"XIAORAN YIN","raw_affiliation_strings":["Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China","institution_ids":["https://openalex.org/I4210131893"]}]},{"author_position":"middle","author":{"id":null,"display_name":"WENTAO XI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210131893","display_name":"Second Affiliated Hospital of Xi'an Jiaotong University","ror":"https://ror.org/03aq7kf18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131893"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"WENTAO XI","raw_affiliation_strings":["Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China","institution_ids":["https://openalex.org/I4210131893"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109136734","display_name":"Weili Min","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210131893","display_name":"Second Affiliated Hospital of Xi'an Jiaotong University","ror":"https://ror.org/03aq7kf18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131893"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"WEILI MIN","raw_affiliation_strings":["Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China","institution_ids":["https://openalex.org/I4210131893"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5075116238"],"corresponding_institution_ids":["https://openalex.org/I4210131893"],"apc_list":null,"apc_paid":null,"fwci":0.5106,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.60996116,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"7","issue":"5","first_page":"1375","last_page":"1380"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.6840999722480774,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.6840999722480774,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11547","display_name":"Sesquiterpenes and Asteraceae Studies","score":0.14810000360012054,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12685","display_name":"Phytochemical compounds biological activities","score":0.026100000366568565,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dihydroartemisinin","display_name":"dihydroartemisinin","score":1.0},{"id":"https://openalex.org/keywords/urokinase-type-plasminogen-activator","display_name":"urokinase","score":0.9980000257492065},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9810000061988831},{"id":"https://openalex.org/keywords/mda-mb-231-cells","display_name":"MDA-MB-231 cells","score":0.9430000185966492},{"id":"https://openalex.org/keywords/mcf-7-cells","display_name":"MCF-7 cells","score":0.8339999914169312},{"id":"https://openalex.org/keywords/tumor-cell-proliferation","display_name":"tumor cell proliferation","score":0.5400000214576721},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.9729999899864197},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.7760000228881836},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.925000011920929},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.5910000205039978}],"concepts":[{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.6456620693206787},{"id":"https://openalex.org/C2779679481","wikidata":"https://www.wikidata.org/wiki/Q13581432","display_name":"Plasminogen activator","level":2,"score":0.6067560315132141},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5779176354408264},{"id":"https://openalex.org/C137738243","wikidata":"https://www.wikidata.org/wiki/Q189092","display_name":"Cell migration","level":3,"score":0.5578166246414185},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.5302695035934448},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.5205160975456238},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.500211238861084},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4856937825679779},{"id":"https://openalex.org/C2781018059","wikidata":"https://www.wikidata.org/wiki/Q207609","display_name":"Oncogene","level":4,"score":0.4679006338119507},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4617960453033447},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.4561970829963684},{"id":"https://openalex.org/C56219504","wikidata":"https://www.wikidata.org/wiki/Q7900869","display_name":"Urokinase receptor","level":3,"score":0.456043541431427},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.4478144645690918},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.4413466155529022},{"id":"https://openalex.org/C2780783641","wikidata":"https://www.wikidata.org/wiki/Q738686","display_name":"MTT assay","level":3,"score":0.42395055294036865},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.42303991317749023},{"id":"https://openalex.org/C2779707156","wikidata":"https://www.wikidata.org/wiki/Q5611758","display_name":"Growth inhibition","level":3,"score":0.4145333468914032},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.38623905181884766},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3688804805278778},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.23607277870178223},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09407338500022888},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3892/ol.2014.1918","doi":"https://doi.org/10.3892/ol.2014.1918","is_oa":true,"landing_page_url":"https://doi.org/10.3892/ol.2014.1918","pdf_url":"https://www.spandidos-publications.com/10.3892/ol.2014.1918/download","source":{"id":"https://openalex.org/S58832373","display_name":"Oncology Letters","issn_l":"1792-1074","issn":["1792-1074","1792-1082"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology Letters","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2975573","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3997666","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:24765140","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24765140","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology letters","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3997666","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3997666/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncol Lett","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3892/ol.2014.1918","doi":"https://doi.org/10.3892/ol.2014.1918","is_oa":true,"landing_page_url":"https://doi.org/10.3892/ol.2014.1918","pdf_url":"https://www.spandidos-publications.com/10.3892/ol.2014.1918/download","source":{"id":"https://openalex.org/S58832373","display_name":"Oncology Letters","issn_l":"1792-1074","issn":["1792-1074","1792-1082"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology Letters","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3259245770","display_name":null,"funder_award_id":"81274136","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320334924","display_name":"Program for New Century Excellent Talents in University","ror":"https://ror.org/01mv9t934"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2010823014.pdf","grobid_xml":"https://content.openalex.org/works/W2010823014.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W1964033920","https://openalex.org/W1969335566","https://openalex.org/W2008290036","https://openalex.org/W2034518537","https://openalex.org/W2044811771","https://openalex.org/W2058105058","https://openalex.org/W2067555721","https://openalex.org/W2080047273","https://openalex.org/W2080537375","https://openalex.org/W2085430724","https://openalex.org/W2096092730","https://openalex.org/W2096787650","https://openalex.org/W2101558299","https://openalex.org/W2131661896","https://openalex.org/W2133082107","https://openalex.org/W2145077705","https://openalex.org/W2152868824","https://openalex.org/W2155498341","https://openalex.org/W2165260026","https://openalex.org/W2416415752"],"related_works":["https://openalex.org/W2379148858","https://openalex.org/W3008752656","https://openalex.org/W2374370638","https://openalex.org/W2373379458","https://openalex.org/W2289188063","https://openalex.org/W2264597796","https://openalex.org/W3134300095","https://openalex.org/W2063013649","https://openalex.org/W3198789649","https://openalex.org/W2047044229"],"abstract_inverted_index":{"The":[0,32,51,63,122,163,189],"aim":[1],"of":[2,12,22,35,61,112,137,156,176,191,205],"the":[3,9,16,23,76,96,110,142,151,157,206],"present":[4,207],"study":[5,208],"was":[6,55,89,106,147,193],"to":[7,94,108,149,195,220],"investigate":[8],"inhibitory":[10,64],"effects":[11],"dihydroartemisinin":[13],"(DHA)":[14],"on":[15,114],"primary":[17],"tumor":[18],"growth":[19,67,164,200],"and":[20,49,69,83,99,133,153,170,179,185,201],"metastasis":[21],"human":[24,123],"breast":[25,119,124,197,221],"cancer":[26,120,125,198,222],"cell":[27,46,53,66,97,126,144,158,199],"line,":[28,127,159],"MDA\u2011MB\u2011231,":[29,128,160],"in":[30,44,118,161,167],"vitro.":[31,162],"expression":[33,117,136],"levels":[34],"urokinase\u2011type":[36],"plasminogen":[37],"activator":[38],"(uPA)":[39],"were":[40,73],"detected":[41],"by":[42,57],"immunocytochemistry":[43],"two":[45],"lines":[47],"(MCF\u20117":[48],"MDA\u2011MB\u2011231).":[50],"MDA\u2011MB\u2011231":[52],"activity":[54],"inhibited":[56],"various":[58,92],"concentration":[59],"gradients":[60],"DHA.":[62],"rate,":[65],"curve":[68],"apoptotic":[70],"morphological":[71],"observations":[72],"obtained":[74],"using":[75],"MTT":[77],"assay":[78],"at":[79,91],"0,":[80],"24,":[81,183],"48":[82,184],"72":[84,186],"h.":[85],"Cell":[86],"scratch":[87],"migration":[88,100,154],"performed":[90],"time\u2011points":[93],"test":[95],"proliferation":[98,152],"capacity.":[101],"Reverse":[102],"transcription\u2011polymerase":[103],"chain":[104],"reaction":[105],"used":[107,214],"analyze":[109],"effect":[111],"DHA":[113,146,211],"uPA":[115,138,192],"mRNA":[116],"cells.":[121],"possesses":[129],"higher":[130,135],"metastatic":[131],"potential":[132],"relatively":[134],"when":[139],"compared":[140],"with":[141,173,218],"MCF-7":[143],"line.":[145],"found":[148],"inhibit":[150],"capacity":[155],"inhibition":[165,190],"occurred":[166],"a":[168],"time\u2011":[169],"dose\u2011dependent":[171],"manner,":[172],"IC50":[174],"values":[175],"117.76\u00b10.04,":[177],"60.26\u00b10.12":[178],"52.96\u00b10.07":[180],"\u00b5mol/l":[181],"following":[182],"h,":[187],"respectively.":[188],"observed":[194],"decrease":[196],"migration.":[202],"Thus,":[203],"results":[204],"indicate":[209],"that":[210],"may":[212],"be":[213],"for":[215],"further":[216],"studies":[217],"regard":[219],"therapy.":[223]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}