{"id":"https://openalex.org/W2010791052","doi":"https://doi.org/10.1182/blood-2003-09-3363","title":"Deletion of the alternatively spliced fibronectin EIIIA domain in mice reduces atherosclerosis","display_name":"Deletion of the alternatively spliced fibronectin EIIIA domain in mice reduces atherosclerosis","publication_year":2004,"publication_date":"2004-02-24","ids":{"openalex":"https://openalex.org/W2010791052","doi":"https://doi.org/10.1182/blood-2003-09-3363","mag":"2010791052","pmid":"https://pubmed.ncbi.nlm.nih.gov/14976060"},"language":"en","primary_location":{"id":"doi:10.1182/blood-2003-09-3363","doi":"https://doi.org/10.1182/blood-2003-09-3363","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood-2003-09-3363","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2010791052"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5105940661","display_name":"Michelle H. Tan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210156491","display_name":"VA Northern California Health Care System","ror":"https://ror.org/05ts0bd12","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210125474","https://openalex.org/I4210156491"]},{"id":"https://openalex.org/I4210157605","display_name":"Sacramento VA Medical Center","ror":"https://ror.org/04ztqy570","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210125474","https://openalex.org/I4210156491","https://openalex.org/I4210157605"]},{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]},{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michelle H. Tan","raw_affiliation_strings":["From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA; the Department of Pathology, Harvard Medical School, Boston, MA; the Department of Medicine, Veterans Administration (VA) Northern California Health Care System, Sacramento VA Medical Center, Mather, CA; and the Department of Internal Medicine, University of California School of Medicine, Davis","From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA","the Department of Internal Medicine, University of California School of Medicine, Davis","the Department of Pathology, Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA; the Department of Pathology, Harvard Medical School, Boston, MA; the Department of Medicine, Veterans Administration (VA) Northern California Health Care System, Sacramento VA Medical Center, Mather, CA; and the Department of Internal Medicine, University of California School of Medicine, Davis","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210156491","https://openalex.org/I4210157605","https://openalex.org/I4210160527","https://openalex.org/I84218800"]},{"raw_affiliation_string":"From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"the Department of Internal Medicine, University of California School of Medicine, Davis","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"the Department of Pathology, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048426664","display_name":"Zhengwu Sun","orcid":"https://orcid.org/0000-0002-4314-0447","observed_orcids":["https://orcid.org/0000-0002-4314-0447"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210156491","display_name":"VA Northern California Health Care System","ror":"https://ror.org/05ts0bd12","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210125474","https://openalex.org/I4210156491"]},{"id":"https://openalex.org/I4210157605","display_name":"Sacramento VA Medical Center","ror":"https://ror.org/04ztqy570","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210125474","https://openalex.org/I4210156491","https://openalex.org/I4210157605"]},{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]},{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhengwu Sun","raw_affiliation_strings":["From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA; the Department of Pathology, Harvard Medical School, Boston, MA; the Department of Medicine, Veterans Administration (VA) Northern California Health Care System, Sacramento VA Medical Center, Mather, CA; and the Department of Internal Medicine, University of California School of Medicine, Davis","From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA","the Department of Internal Medicine, University of California School of Medicine, Davis","the Department of Pathology, Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA; the Department of Pathology, Harvard Medical School, Boston, MA; the Department of Medicine, Veterans Administration (VA) Northern California Health Care System, Sacramento VA Medical Center, Mather, CA; and the Department of Internal Medicine, University of California School of Medicine, Davis","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210156491","https://openalex.org/I4210157605","https://openalex.org/I4210160527","https://openalex.org/I84218800"]},{"raw_affiliation_string":"From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"the Department of Internal Medicine, University of California School of Medicine, Davis","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"the Department of Pathology, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074868014","display_name":"Sarah L. Opitz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210156491","display_name":"VA Northern California Health Care System","ror":"https://ror.org/05ts0bd12","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210125474","https://openalex.org/I4210156491"]},{"id":"https://openalex.org/I4210157605","display_name":"Sacramento VA Medical Center","ror":"https://ror.org/04ztqy570","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210125474","https://openalex.org/I4210156491","https://openalex.org/I4210157605"]},{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]},{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah L. Opitz","raw_affiliation_strings":["From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA; the Department of Pathology, Harvard Medical School, Boston, MA; the Department of Medicine, Veterans Administration (VA) Northern California Health Care System, Sacramento VA Medical Center, Mather, CA; and the Department of Internal Medicine, University of California School of Medicine, Davis","From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA","the Department of Internal Medicine, University of California School of Medicine, Davis","the Department of Pathology, Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA; the Department of Pathology, Harvard Medical School, Boston, MA; the Department of Medicine, Veterans Administration (VA) Northern California Health Care System, Sacramento VA Medical Center, Mather, CA; and the Department of Internal Medicine, University of California School of Medicine, Davis","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210156491","https://openalex.org/I4210157605","https://openalex.org/I4210160527","https://openalex.org/I84218800"]},{"raw_affiliation_string":"From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"the Department of Internal Medicine, University of California School of Medicine, Davis","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"the Department of Pathology, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033147881","display_name":"Tracy E. Schmidt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210156491","display_name":"VA Northern California Health Care System","ror":"https://ror.org/05ts0bd12","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210125474","https://openalex.org/I4210156491"]},{"id":"https://openalex.org/I4210157605","display_name":"Sacramento VA Medical Center","ror":"https://ror.org/04ztqy570","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210125474","https://openalex.org/I4210156491","https://openalex.org/I4210157605"]},{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]},{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tracy E. Schmidt","raw_affiliation_strings":["From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA; the Department of Pathology, Harvard Medical School, Boston, MA; the Department of Medicine, Veterans Administration (VA) Northern California Health Care System, Sacramento VA Medical Center, Mather, CA; and the Department of Internal Medicine, University of California School of Medicine, Davis","From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA","the Department of Internal Medicine, University of California School of Medicine, Davis","the Department of Pathology, Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA; the Department of Pathology, Harvard Medical School, Boston, MA; the Department of Medicine, Veterans Administration (VA) Northern California Health Care System, Sacramento VA Medical Center, Mather, CA; and the Department of Internal Medicine, University of California School of Medicine, Davis","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210156491","https://openalex.org/I4210157605","https://openalex.org/I4210160527","https://openalex.org/I84218800"]},{"raw_affiliation_string":"From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"the Department of Internal Medicine, University of California School of Medicine, Davis","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"the Department of Pathology, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113568335","display_name":"John H. Peters","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210156491","display_name":"VA Northern California Health Care System","ror":"https://ror.org/05ts0bd12","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210125474","https://openalex.org/I4210156491"]},{"id":"https://openalex.org/I4210157605","display_name":"Sacramento VA Medical Center","ror":"https://ror.org/04ztqy570","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210125474","https://openalex.org/I4210156491","https://openalex.org/I4210157605"]},{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]},{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John H. Peters","raw_affiliation_strings":["From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA; the Department of Pathology, Harvard Medical School, Boston, MA; the Department of Medicine, Veterans Administration (VA) Northern California Health Care System, Sacramento VA Medical Center, Mather, CA; and the Department of Internal Medicine, University of California School of Medicine, Davis","From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA","the Department of Internal Medicine, University of California School of Medicine, Davis","the Department of Pathology, Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA; the Department of Pathology, Harvard Medical School, Boston, MA; the Department of Medicine, Veterans Administration (VA) Northern California Health Care System, Sacramento VA Medical Center, Mather, CA; and the Department of Internal Medicine, University of California School of Medicine, Davis","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210156491","https://openalex.org/I4210157605","https://openalex.org/I4210160527","https://openalex.org/I84218800"]},{"raw_affiliation_string":"From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"the Department of Internal Medicine, University of California School of Medicine, Davis","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"the Department of Pathology, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":null,"display_name":"Elizabeth L. George","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210156491","display_name":"VA Northern California Health Care System","ror":"https://ror.org/05ts0bd12","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210125474","https://openalex.org/I4210156491"]},{"id":"https://openalex.org/I4210157605","display_name":"Sacramento VA Medical Center","ror":"https://ror.org/04ztqy570","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210125474","https://openalex.org/I4210156491","https://openalex.org/I4210157605"]},{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]},{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth L. George","raw_affiliation_strings":["From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA; the Department of Pathology, Harvard Medical School, Boston, MA; the Department of Medicine, Veterans Administration (VA) Northern California Health Care System, Sacramento VA Medical Center, Mather, CA; and the Department of Internal Medicine, University of California School of Medicine, Davis","From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA","the Department of Internal Medicine, University of California School of Medicine, Davis","the Department of Pathology, Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA; the Department of Pathology, Harvard Medical School, Boston, MA; the Department of Medicine, Veterans Administration (VA) Northern California Health Care System, Sacramento VA Medical Center, Mather, CA; and the Department of Internal Medicine, University of California School of Medicine, Davis","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210156491","https://openalex.org/I4210157605","https://openalex.org/I4210160527","https://openalex.org/I84218800"]},{"raw_affiliation_string":"From the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"the Department of Internal Medicine, University of California School of Medicine, Davis","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"the Department of Pathology, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5500,"currency":"USD","value_usd":5500},"apc_paid":null,"fwci":5.8665,"has_fulltext":false,"cited_by_count":181,"citation_normalized_percentile":{"value":0.9700881,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"104","issue":"1","first_page":"11","last_page":"18"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.04520000144839287,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fibronectin","display_name":"fibronectin","score":0.8679999709129333},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"alternative splicing","score":0.9419999718666077},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.9929999709129333},{"id":"https://openalex.org/keywords/apoe-null-mice","display_name":"ApoE-null mice","score":0.7390000224113464},{"id":"https://openalex.org/keywords/foam-cells","display_name":"foam cells","score":0.6600000262260437},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.9340000152587891},{"id":"https://openalex.org/keywords/serum-cholesterol","display_name":"serum cholesterol","score":0.6710000038146973},{"id":"https://openalex.org/keywords/lipoprotein-metabolism","display_name":"lipoprotein metabolism","score":0.9010000228881836},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.7910000085830688},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.7870000004768372}],"concepts":[{"id":"https://openalex.org/C57089818","wikidata":"https://www.wikidata.org/wiki/Q424728","display_name":"Apolipoprotein E","level":3,"score":0.767602801322937},{"id":"https://openalex.org/C86492073","wikidata":"https://www.wikidata.org/wiki/Q413766","display_name":"Fibronectin","level":3,"score":0.6666741967201233},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.5292063355445862},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49102115631103516},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.411739706993103},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.31773632764816284},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2711699306964874},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.26157933473587036},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.19298231601715088},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16587767004966736},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D001057","descriptor_name":"Apolipoproteins E","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D001057","descriptor_name":"Apolipoproteins E","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001161","descriptor_name":"Arteriosclerosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001161","descriptor_name":"Arteriosclerosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001161","descriptor_name":"Arteriosclerosis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D004041","descriptor_name":"Dietary Fats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005353","descriptor_name":"Fibronectins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005353","descriptor_name":"Fibronectins","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D005353","descriptor_name":"Fibronectins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005353","descriptor_name":"Fibronectins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005487","descriptor_name":"Foam Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005487","descriptor_name":"Foam Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005487","descriptor_name":"Foam Cells","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008079","descriptor_name":"Lipoproteins, VLDL","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017353","descriptor_name":"Gene Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1182/blood-2003-09-3363","doi":"https://doi.org/10.1182/blood-2003-09-3363","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood-2003-09-3363","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},{"id":"pmid:14976060","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14976060","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"Comparative Study"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.328.7311","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.328.7311","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://bloodjournal.hematologylibrary.org/content/early/2004/02/19/blood-2003-09-3363.full.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1983865571","display_name":"IN VIVO ROLES OF FIBRONECTIN","funder_award_id":"R01GM057719","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2278195778","display_name":null,"funder_award_id":"GM-18241","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G3752930926","display_name":null,"funder_award_id":"GM-57719","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G6409472421","display_name":"IN VIVO ROLES OF FIBRONECTINS IN MICE","funder_award_id":"1f32gm018241-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6772425780","display_name":"UCLA OLDER AMERICANS INDEPENDENCE CENTER","funder_award_id":"P60AG010415","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320309369","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44"},{"id":"https://openalex.org/F4320330645","display_name":"General Administration of Customs","ror":"https://ror.org/00s255r43"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":60,"referenced_works":["https://openalex.org/W132035373","https://openalex.org/W1484163259","https://openalex.org/W1508199610","https://openalex.org/W1531761590","https://openalex.org/W1537033121","https://openalex.org/W1576773659","https://openalex.org/W1589876235","https://openalex.org/W1597673292","https://openalex.org/W1679707032","https://openalex.org/W1743894323","https://openalex.org/W1835542206","https://openalex.org/W1905978178","https://openalex.org/W1939326986","https://openalex.org/W1965576964","https://openalex.org/W1965772617","https://openalex.org/W1991341426","https://openalex.org/W1991731944","https://openalex.org/W1993834457","https://openalex.org/W1994273046","https://openalex.org/W1996736315","https://openalex.org/W1998777645","https://openalex.org/W2000698961","https://openalex.org/W2003291578","https://openalex.org/W2008907994","https://openalex.org/W2010005650","https://openalex.org/W2011405026","https://openalex.org/W2018128871","https://openalex.org/W2029998262","https://openalex.org/W2032961490","https://openalex.org/W2036908471","https://openalex.org/W2038413195","https://openalex.org/W2044008951","https://openalex.org/W2046241907","https://openalex.org/W2046499889","https://openalex.org/W2047617771","https://openalex.org/W2048139403","https://openalex.org/W2048890665","https://openalex.org/W2051093466","https://openalex.org/W2053984681","https://openalex.org/W2055560656","https://openalex.org/W2058823301","https://openalex.org/W2062582674","https://openalex.org/W2066188919","https://openalex.org/W2074660013","https://openalex.org/W2094007386","https://openalex.org/W2098691880","https://openalex.org/W2102915331","https://openalex.org/W2112541119","https://openalex.org/W2121811672","https://openalex.org/W2123055975","https://openalex.org/W2133449490","https://openalex.org/W2137723881","https://openalex.org/W2145532583","https://openalex.org/W2147368533","https://openalex.org/W2147506515","https://openalex.org/W2153245546","https://openalex.org/W2188422153","https://openalex.org/W2324841714","https://openalex.org/W2440922993","https://openalex.org/W4240593622"],"related_works":["https://openalex.org/W7095521569","https://openalex.org/W2042274320","https://openalex.org/W2170186706","https://openalex.org/W2564226897","https://openalex.org/W2099014765","https://openalex.org/W2082798406","https://openalex.org/W2586672249","https://openalex.org/W2253953959","https://openalex.org/W2804264715"],"abstract_inverted_index":{"The":[0],"alternatively":[1],"spliced":[2],"and":[3,27,73,94,128,192],"highly":[4],"conserved":[5],"EIIIA":[6,38,52,92],"domain":[7,53],"of":[8,16,82],"fibronectin":[9],"(FN)":[10],"is":[11,39,55,68],"included":[12,41],"in":[13,20,59,125,134,138,156,162,188,193],"most":[14],"FN":[15,29,58],"the":[17,51,60,80,91,119,157],"extracellular":[18,25],"matrix":[19,26],"embryos.":[21],"In":[22,33,46],"adults,":[23],"both":[24],"plasma":[28,130,147,189],"essentially":[30],"lack":[31,90],"EIIIA.":[32,65],"diverse":[34],"inflammatory":[35],"situations":[36],"however,":[37],"specifically":[40,137],"by":[42],"regulated":[43],"RNA":[44],"splicing.":[45],"atherosclerotic":[47],"lesions,":[48],"FN,":[49],"including":[50],"(EIIIA-FN),":[54],"abundant,":[56],"whereas":[57],"flanking":[61],"vessel":[62,158],"wall":[63,106],"lacks":[64],"Lesional":[66],"EIIIA-FN":[67,122,155,187],"localized":[69],"with":[70,97,109],"endothelial":[71],"cells":[72],"macrophage":[74,154],"foam":[75,164,194],"cells.":[76,177],"To":[77,149],"directly":[78],"test":[79],"function":[81],"EIIIA-FN,":[83],"we":[84,160],"generated":[85],"EIIIA-null":[86],"(EIIIA(-/-))":[87],"mice":[88,102,113],"that":[89,103,183],"exon":[93],"crossed":[95],"them":[96],"apolipoprotein":[98],"E":[99],"(ApoE)-null":[100],"(ApoE(-/-))":[101],"develop":[104],"arterial":[105],"lesions.":[107],"Compared":[108],"ApoE(-/-)":[110,126,176],"controls,":[111],"EIIIA(-/-)ApoE(-/-)":[112,135,167],"had":[114],"significantly":[115,170],"smaller":[116],"lesions":[117],"throughout":[118],"aortic":[120],"tree.":[121],"was":[123,132],"increased":[124],"plasma,":[127],"total":[129],"cholesterol":[131],"reduced":[133],"mice,":[136],"large":[139],"lipoprotein":[140,190],"particles,":[141],"suggesting":[142],"a":[143,151],"functional":[144],"role":[145,152],"for":[146,153,186],"EIIIA-FN.":[148],"assess":[150],"wall,":[159],"conducted":[161],"vitro":[163],"cell":[165,195],"assays.":[166],"macrophages":[168],"accumulated":[169],"less":[171],"intracellular":[172],"lipid":[173],"than":[174],"control":[175],"These":[178],"results":[179],"provide":[180],"genetic":[181],"evidence":[182],"suggests":[184],"roles":[185],"metabolism":[191],"formation.":[196]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":12},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":9}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}