{"id":"https://openalex.org/W2010741345","doi":"https://doi.org/10.1213/01.ane.0000180992.76743.c9","title":"Does Neostigmine Administration Produce a Clinically Important Increase in Postoperative Nausea and Vomiting?","display_name":"Does Neostigmine Administration Produce a Clinically Important Increase in Postoperative Nausea and Vomiting?","publication_year":2005,"publication_date":"2005-10-11","ids":{"openalex":"https://openalex.org/W2010741345","doi":"https://doi.org/10.1213/01.ane.0000180992.76743.c9","mag":"2010741345","pmid":"https://pubmed.ncbi.nlm.nih.gov/16243993","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1458621"},"language":"en","primary_location":{"id":"doi:10.1213/01.ane.0000180992.76743.c9","doi":"https://doi.org/10.1213/01.ane.0000180992.76743.c9","is_oa":false,"landing_page_url":"https://doi.org/10.1213/01.ane.0000180992.76743.c9","pdf_url":null,"source":{"id":"https://openalex.org/S104698359","display_name":"Anesthesia & Analgesia","issn_l":"0003-2999","issn":["0003-2999","1526-7598"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anesthesia &amp; Analgesia","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1458621/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5105366617","display_name":"Ching-Rong Cheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]},{"id":"https://openalex.org/I4210108246","display_name":"Joseph Drown Foundation","ror":"https://ror.org/01pe6xq34","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210108246"]},{"id":"https://openalex.org/I4210145156","display_name":"Gheens Foundation","ror":"https://ror.org/048h18548","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210145156"]},{"id":"https://openalex.org/I4405271661","display_name":"Commonwealth of Kentucky","ror":"https://ror.org/02t4yge16","country_code":"US","type":"government","lineage":["https://openalex.org/I4405271661"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ching-Rong Cheng","raw_affiliation_strings":["Outcomes Research Institute and Department of Anesthesiology and Perioperative Medicine, University of Louisville, Louisville, Kentucky","Accepted for publication May 12, 2005","Supported, in part, by National Institutes of Health Grant GM 061655 (Bethesda, MD), the Gheens Foundation (Louisville, KY), the Joseph Drown Foundation (Los Angeles, CA), and the Commonwealth of Kentucky Research Challenge Trust Fund (Louisville, KY)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Outcomes Research Institute and Department of Anesthesiology and Perioperative Medicine, University of Louisville, Louisville, Kentucky","institution_ids":["https://openalex.org/I142740786"]},{"raw_affiliation_string":"Accepted for publication May 12, 2005","institution_ids":[]},{"raw_affiliation_string":"Supported, in part, by National Institutes of Health Grant GM 061655 (Bethesda, MD), the Gheens Foundation (Louisville, KY), the Joseph Drown Foundation (Los Angeles, CA), and the Commonwealth of Kentucky Research Challenge Trust Fund (Louisville, KY)","institution_ids":["https://openalex.org/I4210108246","https://openalex.org/I4210145156","https://openalex.org/I4405271661"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042996287","display_name":"Daniel I. Sessler","orcid":"https://orcid.org/0000-0001-9932-3077","observed_orcids":["https://orcid.org/0000-0001-9932-3077"]},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]},{"id":"https://openalex.org/I4210108246","display_name":"Joseph Drown Foundation","ror":"https://ror.org/01pe6xq34","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210108246"]},{"id":"https://openalex.org/I4210145156","display_name":"Gheens Foundation","ror":"https://ror.org/048h18548","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210145156"]},{"id":"https://openalex.org/I4405271661","display_name":"Commonwealth of Kentucky","ror":"https://ror.org/02t4yge16","country_code":"US","type":"government","lineage":["https://openalex.org/I4405271661"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel I. Sessler","raw_affiliation_strings":["Outcomes Research Institute and Department of Anesthesiology and Perioperative Medicine, University of Louisville, Louisville, Kentucky","Accepted for publication May 12, 2005","Supported, in part, by National Institutes of Health Grant GM 061655 (Bethesda, MD), the Gheens Foundation (Louisville, KY), the Joseph Drown Foundation (Los Angeles, CA), and the Commonwealth of Kentucky Research Challenge Trust Fund (Louisville, KY)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Outcomes Research Institute and Department of Anesthesiology and Perioperative Medicine, University of Louisville, Louisville, Kentucky","institution_ids":["https://openalex.org/I142740786"]},{"raw_affiliation_string":"Accepted for publication May 12, 2005","institution_ids":[]},{"raw_affiliation_string":"Supported, in part, by National Institutes of Health Grant GM 061655 (Bethesda, MD), the Gheens Foundation (Louisville, KY), the Joseph Drown Foundation (Los Angeles, CA), and the Commonwealth of Kentucky Research Challenge Trust Fund (Louisville, KY)","institution_ids":["https://openalex.org/I4210108246","https://openalex.org/I4210145156","https://openalex.org/I4405271661"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015537537","display_name":"Christian C. Apfel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]},{"id":"https://openalex.org/I4210108246","display_name":"Joseph Drown Foundation","ror":"https://ror.org/01pe6xq34","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210108246"]},{"id":"https://openalex.org/I4210145156","display_name":"Gheens Foundation","ror":"https://ror.org/048h18548","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210145156"]},{"id":"https://openalex.org/I4405271661","display_name":"Commonwealth of Kentucky","ror":"https://ror.org/02t4yge16","country_code":"US","type":"government","lineage":["https://openalex.org/I4405271661"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Christian C. Apfel","raw_affiliation_strings":["Outcomes Research Institute and Department of Anesthesiology and Perioperative Medicine, University of Louisville, Louisville, Kentucky","and reprint requests to Christian Apfel, MD, 501 E. Broadway, Suite 210, Louisville, KY, 40202. Address electronic mail to [email\u00a0protected]","Accepted for publication May 12, 2005","Supported, in part, by National Institutes of Health Grant GM 061655 (Bethesda, MD), the Gheens Foundation (Louisville, KY), the Joseph Drown Foundation (Los Angeles, CA), and the Commonwealth of Kentucky Research Challenge Trust Fund (Louisville, KY)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Outcomes Research Institute and Department of Anesthesiology and Perioperative Medicine, University of Louisville, Louisville, Kentucky","institution_ids":["https://openalex.org/I142740786"]},{"raw_affiliation_string":"and reprint requests to Christian Apfel, MD, 501 E. Broadway, Suite 210, Louisville, KY, 40202. Address electronic mail to [email\u00a0protected]","institution_ids":[]},{"raw_affiliation_string":"Accepted for publication May 12, 2005","institution_ids":[]},{"raw_affiliation_string":"Supported, in part, by National Institutes of Health Grant GM 061655 (Bethesda, MD), the Gheens Foundation (Louisville, KY), the Joseph Drown Foundation (Los Angeles, CA), and the Commonwealth of Kentucky Research Challenge Trust Fund (Louisville, KY)","institution_ids":["https://openalex.org/I4210108246","https://openalex.org/I4210145156","https://openalex.org/I4405271661"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5015537537"],"corresponding_institution_ids":["https://openalex.org/I142740786","https://openalex.org/I4210108246","https://openalex.org/I4210145156","https://openalex.org/I4405271661"],"apc_list":null,"apc_paid":null,"fwci":1.044,"has_fulltext":false,"cited_by_count":104,"citation_normalized_percentile":{"value":0.7,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"101","issue":"5","first_page":"1349","last_page":"1355"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11785","display_name":"Nausea and vomiting management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11785","display_name":"Nausea and vomiting management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10189","display_name":"Anesthesia and Pain Management","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neostigmine","display_name":"neostigmine","score":1.0},{"id":"https://openalex.org/keywords/postoperative-nausea-and-vomiting","display_name":"postoperative nausea and vomiting","score":0.996999979019165},{"id":"https://openalex.org/keywords/anticholinergic-drugs","display_name":"anticholinergic agents","score":0.7260000109672546},{"id":"https://openalex.org/keywords/atropine","display_name":"atropine","score":0.9879999756813049},{"id":"https://openalex.org/keywords/glycopyrrolate","display_name":"glycopyrrolate","score":0.9990000128746033},{"id":"https://openalex.org/keywords/neuromuscular-blockade-reversal","display_name":"neuromuscular blockade reversal","score":0.8009999990463257},{"id":"https://openalex.org/keywords/residual-neuromuscular-block","display_name":"residual neuromuscular blockade","score":0.9169999957084656},{"id":"https://openalex.org/keywords/dose-response-relationship","display_name":"dose-response relationship","score":0.4699999988079071},{"id":"https://openalex.org/keywords/confounding-factors","display_name":"confounding factors","score":0.6779999732971191}],"concepts":[{"id":"https://openalex.org/C2777411258","wikidata":"https://www.wikidata.org/wiki/Q410546","display_name":"Neostigmine","level":2,"score":0.9412360191345215},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8582361936569214},{"id":"https://openalex.org/C2780580376","wikidata":"https://www.wikidata.org/wiki/Q186889","display_name":"Nausea","level":2,"score":0.8490495681762695},{"id":"https://openalex.org/C2780852908","wikidata":"https://www.wikidata.org/wiki/Q127076","display_name":"Vomiting","level":2,"score":0.8315892219543457},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.6929979920387268},{"id":"https://openalex.org/C2777297131","wikidata":"https://www.wikidata.org/wiki/Q1658731","display_name":"Postoperative nausea and vomiting","level":3,"score":0.6433060765266418},{"id":"https://openalex.org/C2776478404","wikidata":"https://www.wikidata.org/wiki/Q1105187","display_name":"Cochrane Library","level":3,"score":0.5960820913314819},{"id":"https://openalex.org/C82789193","wikidata":"https://www.wikidata.org/wiki/Q2142611","display_name":"Relative risk","level":3,"score":0.45055580139160156},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.428104043006897},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21071842312812805}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009388","descriptor_name":"Neostigmine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D009466","descriptor_name":"Neuromuscular Blocking Agents","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020250","descriptor_name":"Postoperative Nausea and Vomiting","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1213/01.ane.0000180992.76743.c9","doi":"https://doi.org/10.1213/01.ane.0000180992.76743.c9","is_oa":false,"landing_page_url":"https://doi.org/10.1213/01.ane.0000180992.76743.c9","pdf_url":null,"source":{"id":"https://openalex.org/S104698359","display_name":"Anesthesia & Analgesia","issn_l":"0003-2999","issn":["0003-2999","1526-7598"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anesthesia &amp; Analgesia","raw_type":"journal-article"},{"id":"pmid:16243993","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16243993","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anesthesia and analgesia","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1458621","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1458621/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Anesth Analg","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1458621","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1458621/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Anesth Analg","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9922999739646912,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[{"id":"https://openalex.org/G3106184739","display_name":"Nitrous Oxide and Wound Infections","funder_award_id":"R01GM061655","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G4523917896","display_name":null,"funder_award_id":"GM 0616555","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W204046373","https://openalex.org/W297661399","https://openalex.org/W1480729244","https://openalex.org/W1603360277","https://openalex.org/W1964502233","https://openalex.org/W1969144595","https://openalex.org/W1973094814","https://openalex.org/W1974310361","https://openalex.org/W1974975370","https://openalex.org/W1974988711","https://openalex.org/W1975220183","https://openalex.org/W1979408319","https://openalex.org/W1980344021","https://openalex.org/W1980533538","https://openalex.org/W1986215651","https://openalex.org/W2015583732","https://openalex.org/W2019322190","https://openalex.org/W2038693293","https://openalex.org/W2048346332","https://openalex.org/W2059048202","https://openalex.org/W2071076560","https://openalex.org/W2076585267","https://openalex.org/W2084422072","https://openalex.org/W2084511020","https://openalex.org/W2091570756","https://openalex.org/W2094360741","https://openalex.org/W2098200269","https://openalex.org/W2115798964","https://openalex.org/W2117875510","https://openalex.org/W2127807801","https://openalex.org/W2127992301","https://openalex.org/W2128488589","https://openalex.org/W2141656439","https://openalex.org/W2146001292","https://openalex.org/W2154735290","https://openalex.org/W2164261563","https://openalex.org/W2165137445","https://openalex.org/W2409433523","https://openalex.org/W2413843002"],"related_works":["https://openalex.org/W7096355078","https://openalex.org/W1975220183","https://openalex.org/W2071076560","https://openalex.org/W2128488589","https://openalex.org/W2084511020","https://openalex.org/W2409433523","https://openalex.org/W7095460616","https://openalex.org/W2141656439","https://openalex.org/W1980344021","https://openalex.org/W1993098934"],"abstract_inverted_index":{"Neostigmine":[0],"is":[1,199],"used":[2],"to":[3,202],"antagonize":[4],"neuromuscular":[5,8],"blocker-induced":[6],"residual":[7],"paralysis.":[9],"Despite":[10],"the":[11,17,30,41,97,137,179,207],"findings":[12],"of":[13,19,32,126,139,181,189,209],"a":[14,50,175,192],"previous":[15,193],"meta-analysis,":[16],"effect":[18,31,80],"neostigmine":[20,33,127,205],"on":[21,34,81,87],"postoperative":[22,35,82,108,210],"nausea":[23,36,83,88,155,211],"and":[24,37,61,71,84,104,110,119,212],"vomiting":[25,38,90,143,182],"remains":[26],"unresolved.":[27],"We":[28,48],"reevaluated":[29],"while":[39],"considering":[40],"different":[42],"anticholinergics":[43],"as":[44],"potentially":[45],"confounding":[46],"factors.":[47],"performed":[49],"systematic":[51],"literature":[52],"search":[53],"using":[54],"MEDLINE,":[55],"Embase,":[56],"Cochrane":[57],"library,":[58],"reference":[59],"listings,":[60],"hand":[62],"searching":[63],"with":[64,112,128,183,186],"no":[65],"language":[66],"restriction":[67],"through":[68],"December":[69],"2004":[70],"identified":[72],"10":[73],"clinical,":[74],"randomized,":[75],"controlled":[76],"trials":[77],"evaluating":[78],"neostigmine's":[79],"vomiting.":[85,213],"Data":[86],"or":[89,131,154],"from":[91],"933":[92],"patients":[93],"were":[94],"extracted":[95],"for":[96],"early":[98],"(0-6":[99],"h),":[100,103],"delayed":[101],"(6-24":[102],"overall":[105,140],"(0-24":[106,141],"h)":[107,142],"periods":[109],"analyzed":[111],"RevMan":[113],"4.2":[114],"(Cochrane":[115],"Collaboration,":[116],"Oxford,":[117],"UK)":[118],"multiple":[120],"logistic":[121,167],"regression":[122,168],"analysis.":[123],"The":[124],"combination":[125],"either":[129],"atropine":[130],"glycopyrrolate":[132],"did":[133],"not":[134,174],"significantly":[135],"increase":[136,177],"incidence":[138],"(relative":[144,156],"risk,":[145,157],"0.91;":[146],"95%":[147,159],"confidence":[148,160],"interval,":[149,161],"0.70-1.18;":[150],"P":[151,163],"=":[152,164],"0.48)":[153],"1.24;":[158],"0.98-1.59;":[162],"0.08).":[165],"Multiple":[166],"analysis":[169],"indicated":[170],"that":[171,197,204],"there":[172,198],"was":[173],"significant":[176],"in":[178],"risk":[180,208],"large":[184],"compared":[185],"small":[187],"doses":[188],"neostigmine.":[190],"Contrasting":[191],"analysis,":[194],"we":[195],"conclude":[196,203],"insufficient":[200],"evidence":[201],"increases":[206]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
