{"id":"https://openalex.org/W2010705282","doi":"https://doi.org/10.1159/000046092","title":"Vitamin D Receptor Gene Polymorphism Detected by Digestion with Apa I Influences the Parathyroid Response to Extracellular Calcium in Japanese Chronic Dialysis Patients","display_name":"Vitamin D Receptor Gene Polymorphism Detected by Digestion with Apa I Influences the Parathyroid Response to Extracellular Calcium in Japanese Chronic Dialysis Patients","publication_year":2001,"publication_date":"2001-01-01","ids":{"openalex":"https://openalex.org/W2010705282","doi":"https://doi.org/10.1159/000046092","mag":"2010705282","pmid":"https://pubmed.ncbi.nlm.nih.gov/11598396"},"language":"en","primary_location":{"id":"doi:10.1159/000046092","doi":"https://doi.org/10.1159/000046092","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000046092","pdf_url":null,"source":{"id":"https://openalex.org/S4393917655","display_name":"The Nephron journals/Nephron journals","issn_l":"1660-8151","issn":["1660-8151","2235-3186"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephron","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053498181","display_name":"Keitaro Yokoyama","orcid":"https://orcid.org/0000-0002-6122-592X","observed_orcids":["https://orcid.org/0000-0002-6122-592X"]},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Keitaro Yokoyama","raw_affiliation_strings":["Division of Nephrology and Hypertension, Jikei University School of Medicine, Tokyo, Japan. keitaro@mrj.biglobe.ne.jp","Division of Nephrology and Hypertension, Jikei University School of Medicine, Tokyo,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology and Hypertension, Jikei University School of Medicine, Tokyo, Japan. keitaro@mrj.biglobe.ne.jp","institution_ids":["https://openalex.org/I115498069"]},{"raw_affiliation_string":"Division of Nephrology and Hypertension, Jikei University School of Medicine, Tokyo,","institution_ids":["https://openalex.org/I115498069"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063644416","display_name":"Takashi Shigematsu","orcid":"https://orcid.org/0000-0002-6330-3784","observed_orcids":["https://orcid.org/0000-0002-6330-3784"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Takashi Shigematsu","raw_affiliation_strings":["Nephrology and Dialysis Unit, Department of Internal Medicine, Sakura National Hospital, Sakura, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nephrology and Dialysis Unit, Department of Internal Medicine, Sakura National Hospital, Sakura, and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110014599","display_name":"S Kagami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Sino Kagami","raw_affiliation_strings":["Division of Nephrology and Hypertension, Jikei University School of Medicine, Tokyo,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology and Hypertension, Jikei University School of Medicine, Tokyo,","institution_ids":["https://openalex.org/I115498069"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110641775","display_name":"Toshihiko Tsukada","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Toshihiko Tsukada","raw_affiliation_strings":["Department of Clinical Physiology, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Physiology, and","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Tomoko Arai","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tomoko Arai","raw_affiliation_strings":["Department of Clinical Physiology, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Physiology, and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109631719","display_name":"Sigeko Hara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166463","display_name":"Toranomon Hospital","ror":"https://ror.org/05rkz5e28","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210166463"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Sigeko Hara","raw_affiliation_strings":["Kidney Center, Toranomon Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kidney Center, Toranomon Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4210166463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088207236","display_name":"Akira Yamada","orcid":"https://orcid.org/0000-0002-4199-203X","observed_orcids":["https://orcid.org/0000-0002-4199-203X"]},"institutions":[{"id":"https://openalex.org/I4210166463","display_name":"Toranomon Hospital","ror":"https://ror.org/05rkz5e28","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210166463"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akira Yamada","raw_affiliation_strings":["Kidney Center, Toranomon Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kidney Center, Toranomon Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4210166463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113697045","display_name":"Yoshindo Kawaguchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshindo Kawaguchi","raw_affiliation_strings":["Division of Nephrology and Hypertension, Jikei University School of Medicine, Tokyo,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology and Hypertension, Jikei University School of Medicine, Tokyo,","institution_ids":["https://openalex.org/I115498069"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113586910","display_name":"Tatsuo Hosoya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tatsuo Hosoya","raw_affiliation_strings":["Division of Nephrology and Hypertension, Jikei University School of Medicine, Tokyo,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology and Hypertension, Jikei University School of Medicine, Tokyo,","institution_ids":["https://openalex.org/I115498069"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1996,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.80465116,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"89","issue":"3","first_page":"315","last_page":"320"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.014399999752640724,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12975","display_name":"Paraoxonase enzyme and polymorphisms","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vdr-polymorphisms","display_name":"VDR polymorphisms","score":0.9419999718666077},{"id":"https://openalex.org/keywords/parathyroid-hormone","display_name":"parathyroid hormone","score":0.8090000152587891},{"id":"https://openalex.org/keywords/extracellular-calcium","display_name":"extracellular calcium","score":0.7979999780654907},{"id":"https://openalex.org/keywords/dialysate-calcium-concentration","display_name":"dialysate calcium concentration","score":0.9179999828338623},{"id":"https://openalex.org/keywords/hemodialysis","display_name":"hemodialysis","score":0.8700000047683716},{"id":"https://openalex.org/keywords/end-stage-renal-disease","display_name":"end-stage renal disease","score":0.9810000061988831},{"id":"https://openalex.org/keywords/chronic-dialysis-patients","display_name":"chronic dialysis patients","score":0.7990000247955322},{"id":"https://openalex.org/keywords/1-25-dihydroxyvitamin-d3","display_name":"1,25-dihydroxyvitamin D3","score":0.8650000095367432},{"id":"https://openalex.org/keywords/serum-phosphorus","display_name":"serum phosphorus","score":0.7160000205039978},{"id":"https://openalex.org/keywords/genetic-polymorphism","display_name":"genetic polymorphism","score":0.5049999952316284},{"id":"https://openalex.org/keywords/japanese-patients","display_name":"Japanese patients","score":0.8109999895095825},{"id":"https://openalex.org/keywords/genotype-distribution","display_name":"genotype distribution","score":0.3440000116825104}],"concepts":[{"id":"https://openalex.org/C179639408","wikidata":"https://www.wikidata.org/wiki/Q417057","display_name":"Calcitriol receptor","level":3,"score":0.8831207752227783},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7561696171760559},{"id":"https://openalex.org/C2781208988","wikidata":"https://www.wikidata.org/wiki/Q202476","display_name":"Parathyroid hormone","level":3,"score":0.7116131782531738},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7069371938705444},{"id":"https://openalex.org/C124490489","wikidata":"https://www.wikidata.org/wiki/Q7936963","display_name":"Vitamin D and neurology","level":2,"score":0.5899055600166321},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5403326749801636},{"id":"https://openalex.org/C3019040382","wikidata":"https://www.wikidata.org/wiki/Q476921","display_name":"End stage renal disease","level":3,"score":0.5337072014808655},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.5009751319885254},{"id":"https://openalex.org/C76252995","wikidata":"https://www.wikidata.org/wiki/Q3395645","display_name":"Gene polymorphism","level":4,"score":0.470206081867218},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.4511019289493561},{"id":"https://openalex.org/C2778063415","wikidata":"https://www.wikidata.org/wiki/Q391744","display_name":"Hemodialysis","level":2,"score":0.4022497236728668},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.35538068413734436},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32529574632644653},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2040386199951172},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15306538343429565}],"mesh":[{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006435","descriptor_name":"Renal Dialysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006961","descriptor_name":"Hyperparathyroidism","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006961","descriptor_name":"Hyperparathyroidism","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":false},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010280","descriptor_name":"Parathyroid Glands","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D010280","descriptor_name":"Parathyroid Glands","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010281","descriptor_name":"Parathyroid Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010281","descriptor_name":"Parathyroid Hormone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010758","descriptor_name":"Phosphorus","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011110","descriptor_name":"Polymorphism, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012150","descriptor_name":"Polymorphism, Restriction Fragment Length","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015314","descriptor_name":"Dialysis Solutions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018167","descriptor_name":"Receptors, Calcitriol","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018167","descriptor_name":"Receptors, Calcitriol","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1159/000046092","doi":"https://doi.org/10.1159/000046092","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000046092","pdf_url":null,"source":{"id":"https://openalex.org/S4393917655","display_name":"The Nephron journals/Nephron journals","issn_l":"1660-8151","issn":["1660-8151","2235-3186"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephron","raw_type":"journal-article"},{"id":"pmid:11598396","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11598396","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephron","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1965551846","https://openalex.org/W1985061152","https://openalex.org/W1995225079","https://openalex.org/W1995761871","https://openalex.org/W2004389367","https://openalex.org/W2009180025","https://openalex.org/W2013679580","https://openalex.org/W2018381121","https://openalex.org/W2020042050","https://openalex.org/W2023897144","https://openalex.org/W2055754838","https://openalex.org/W2059011317","https://openalex.org/W2069881608","https://openalex.org/W2070504970","https://openalex.org/W2071004197","https://openalex.org/W2078612158","https://openalex.org/W2081074472","https://openalex.org/W2082708611","https://openalex.org/W2082740217","https://openalex.org/W2083168164","https://openalex.org/W2122847718","https://openalex.org/W2128254668","https://openalex.org/W2142384973","https://openalex.org/W2143878967","https://openalex.org/W2155778995","https://openalex.org/W2288159275","https://openalex.org/W2337884406","https://openalex.org/W2402300034"],"related_works":["https://openalex.org/W1995761871","https://openalex.org/W7144740625","https://openalex.org/W6988801953","https://openalex.org/W2122847718","https://openalex.org/W2071004197","https://openalex.org/W1873898390","https://openalex.org/W1978585142","https://openalex.org/W2079771803","https://openalex.org/W1965025909","https://openalex.org/W2471731109"],"abstract_inverted_index":{"BACKGROUND:":[0],"To":[1],"play":[2],"its":[3],"physiological":[4],"role,":[5],"1,25(OH)2D3":[6],"must":[7],"bind":[8],"to":[9,337,358],"a":[10,123,240],"specific":[11],"vitamin":[12],"D":[13],"receptor":[14],"(VDR)":[15],"in":[16,31,69,81,161,180,222,226,265,272,287,290,312,331,339,343,360,363,372],"the":[17,28,39,45,48,58,65,70,96,105,198,213,216,232,247,255,284,329,350],"nucleus.":[18],"We":[19],"have":[20,43],"previously":[21],"reported":[22],"that":[23,328,349],"VDR":[24,52,106,351],"gene":[25,53,107,352],"polymorphism":[26,353],"influences":[27],"parathyroid":[29,49,134,356],"function":[30],"patients":[32,76,182,185,189,330],"with":[33,146,197,231,254,298],"end-stage":[34],"renal":[35,78],"disease":[36],"(ESRD).":[37],"In":[38],"present":[40],"study,":[41],"we":[42],"investigated":[44],"relationship":[46],"between":[47,98,206,283],"responsiveness":[50,357],"and":[51,93,101,121,132,140,175,187,209,295,303,368],"polymorphism,":[54],"as":[55],"detected":[56],"by":[57,63],"Apa":[59,109],"I":[60,110],"restriction":[61],"enzyme,":[62],"changing":[64],"concentration":[66],"of":[67,104,151,159,169,250,317,370],"Ca2+":[68,152],"dialysate.":[71,300],"METHODS:":[72],"58":[73],"Japanese":[74],"ESRD":[75,373],"undergoing":[77],"replacement":[79],"therapy":[80],"our":[82],"institution":[83],"were":[84,114,137,178,279,334],"evaluated.":[85],"Genomic":[86],"DNA":[87],"was":[88,164,219,259],"extracted":[89],"from":[90],"peripheral":[91],"leukocytes":[92],"digested":[94],"at":[95],"intron":[97],"exon":[99,102],"8":[100],"9":[103],"using":[108],"enzyme.":[111],"Then":[112],"alleles":[113],"classified":[115],"into":[116],"genotype":[117,122],"A":[118],"(undigested":[119],"allele)":[120],"(digested":[124],"allele).":[125],"Extracellular":[126],"ionized":[127],"calcium":[128],"([Ca2+]e),":[129],"serum":[130,291],"phosphate,":[131],"intact":[133],"hormone":[135],"(PTH)":[136],"measured":[138],"before":[139,244,294],"after":[141,195,229,252,296],"each":[142],"hemodialysis":[143],"(HD)":[144],"session":[145],"dialysates":[147],"having":[148],"different":[149],"concentrations":[150],"(1.5":[153],"or":[154,320],"1.25":[155],"mmol/l).":[156],"The":[157,172,192,324],"significance":[158],"differences":[160,282,311],"statistical":[162],"analyses":[163],"defined":[165],"within":[166],"confidence":[167],"limits":[168],"5.0%.":[170],"RESULTS:":[171],"AA,":[173],"Aa,":[174],"aa":[176,224,267,305,333],"genotypes":[177],"observed":[179],"7/58":[181],"(12.1%),":[183],"23/58":[184],"(39.6%),":[186],"28/58":[188],"(48.3%),":[190],"respectively.":[191],"PTH":[193,217,242,251],"reduction":[194],"HD":[196,230,253,297],"1.5-mmol/l":[199],"Ca":[200,234,257],"dialysate":[201,235,258],"did":[202,306],"not":[203,307],"differ":[204],"significantly":[205,220,260],"group":[207,210,223,227,266,273,304,332,344],"AA+Aa":[208,228,274,302],"aa.":[211],"On":[212],"other":[214],"hand,":[215],"increase":[218,249],"higher":[221,261],"than":[225,271,341],"1.25-mmol/l":[233,256],"(p":[236,262],"=":[237,263],"0.0107),":[238],"despite":[239],"similar":[241],"level":[243],"HD.":[245],"Similarly,":[246],"percent":[248],"0.0112)":[264],"(50.2":[268],"+/-":[269,276],"9.4%)":[270],"(19.7":[275],"7.2%).":[277],"There":[278],"no":[280],"significant":[281,310],"two":[285],"groups":[286],"[Ca2+]e":[288,340],"nor":[289],"phosphorus":[292],"(Pi)":[293],"either":[299],"Group":[301],"show":[308],"statistically":[309],"age,":[313],"female/male":[314],"ratio,":[315],"ratio":[316],"diabetic":[318],"nephropathy,":[319],"dialysis":[321],"period.":[322],"CONCLUSIONS:":[323],"study":[325],"results":[326],"showed":[327],"more":[335],"sensitive":[336],"changes":[338,359],"those":[342],"AA+Aa.":[345],"Moreover,":[346],"they":[347],"suggested":[348],"may":[354,365],"affect":[355],"[Ca2+]e,":[361],"which":[362],"turn":[364],"influence":[366],"onset":[367],"progression":[369],"hyperparathyroidism":[371],"patients.":[374]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}