{"id":"https://openalex.org/W2010620848","doi":"https://doi.org/10.1016/j.ejmech.2010.09.050","title":"Synthesis, antitrichinnellosis and antiprotozoal activity of some novel thieno[2,3-d]pyrimidin-4(3H)-ones containing benzimidazole ring","display_name":"Synthesis, antitrichinnellosis and antiprotozoal activity of some novel thieno[2,3-d]pyrimidin-4(3H)-ones containing benzimidazole ring","publication_year":2010,"publication_date":"2010-09-28","ids":{"openalex":"https://openalex.org/W2010620848","doi":"https://doi.org/10.1016/j.ejmech.2010.09.050","mag":"2010620848","pmid":"https://pubmed.ncbi.nlm.nih.gov/20950896"},"language":"en","primary_location":{"id":"doi:10.1016/j.ejmech.2010.09.050","doi":"https://doi.org/10.1016/j.ejmech.2010.09.050","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ejmech.2010.09.050","pdf_url":null,"source":{"id":"https://openalex.org/S4210169613","display_name":"European Journal of Medicinal Chemistry","issn_l":"0223-5234","issn":["0223-5234","1768-3254"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Medicinal Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067737927","display_name":"Anelia Ts. Mavrova","orcid":"https://orcid.org/0000-0002-0455-4321","observed_orcids":["https://orcid.org/0000-0002-0455-4321"]},"institutions":[{"id":"https://openalex.org/I4210148616","display_name":"University of Chemical Technology and Metallurgy","ror":"https://ror.org/0402pty94","country_code":"BG","type":"education","lineage":["https://openalex.org/I4210148616"]}],"countries":["BG"],"is_corresponding":true,"raw_author_name":"Anelia Ts. Mavrova","raw_affiliation_strings":["Department of Organic Synthesis, University of Chemical Technology and Metallurgy, 8Kliment Ohridski Blvd., 1756 Sofia, Bulgaria. anmav@abv.bg","Department of Organic Synthesis, University of Chemical Technology and Metallurgy, 8Kliment Ohridski Blvd., 1756 Sofia, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Organic Synthesis, University of Chemical Technology and Metallurgy, 8Kliment Ohridski Blvd., 1756 Sofia, Bulgaria. anmav@abv.bg","institution_ids":["https://openalex.org/I4210148616"]},{"raw_affiliation_string":"Department of Organic Synthesis, University of Chemical Technology and Metallurgy, 8Kliment Ohridski Blvd., 1756 Sofia, Bulgaria","institution_ids":["https://openalex.org/I4210148616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041931992","display_name":"Dimitar Vuchev","orcid":"https://orcid.org/0000-0002-4315-6203","observed_orcids":["https://orcid.org/0000-0002-4315-6203"]},"institutions":[{"id":"https://openalex.org/I2801117330","display_name":"Medical University Plovdiv","ror":"https://ror.org/02kzxd152","country_code":"BG","type":"education","lineage":["https://openalex.org/I2801117330"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Dimitar Vuchev","raw_affiliation_strings":["Medicinal University, Section of Parasitology and Tropical deseases, Plovdiv, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal University, Section of Parasitology and Tropical deseases, Plovdiv, Bulgaria","institution_ids":["https://openalex.org/I2801117330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079765482","display_name":"Kameliya Anichina","orcid":"https://orcid.org/0000-0001-5236-0567","observed_orcids":["https://orcid.org/0000-0001-5236-0567"]},"institutions":[{"id":"https://openalex.org/I4210148616","display_name":"University of Chemical Technology and Metallurgy","ror":"https://ror.org/0402pty94","country_code":"BG","type":"education","lineage":["https://openalex.org/I4210148616"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Kameliya Anichina","raw_affiliation_strings":["Department of Organic Synthesis, University of Chemical Technology and Metallurgy, 8Kliment Ohridski Blvd., 1756 Sofia, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Organic Synthesis, University of Chemical Technology and Metallurgy, 8Kliment Ohridski Blvd., 1756 Sofia, Bulgaria","institution_ids":["https://openalex.org/I4210148616"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032725056","display_name":"Nikolay Georgiev Vassilev","orcid":"https://orcid.org/0000-0002-8781-2866","observed_orcids":["https://orcid.org/0000-0002-8781-2866"]},"institutions":[{"id":"https://openalex.org/I24768866","display_name":"Bulgarian Academy of Sciences","ror":"https://ror.org/01x8hew03","country_code":"BG","type":"government","lineage":["https://openalex.org/I24768866"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Nikolay Vassilev","raw_affiliation_strings":["Institute of Organic Chemistry, Bulgarian Academy of Science, 1113 Sofia, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Organic Chemistry, Bulgarian Academy of Science, 1113 Sofia, Bulgaria","institution_ids":["https://openalex.org/I24768866"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5067737927"],"corresponding_institution_ids":["https://openalex.org/I4210148616"],"apc_list":{"value":4650,"currency":"USD","value_usd":4650},"apc_paid":null,"fwci":2.6617,"has_fulltext":false,"cited_by_count":82,"citation_normalized_percentile":{"value":0.89243256,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"45","issue":"12","first_page":"5856","last_page":"5861"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.5156000256538391,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.5156000256538391,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14099","display_name":"Synthesis and Characterization of Heterocyclic Compounds","score":0.20730000734329224,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11702","display_name":"Parasitic Diseases Research and Treatment","score":0.18870000541210175,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/benzimidazole-derivatives","display_name":"benzimidazole derivatives","score":0.9810000061988831},{"id":"https://openalex.org/keywords/antiprotozoal-activity","display_name":"antiprotozoal activity","score":0.9559999704360962},{"id":"https://openalex.org/keywords/trichinella-spiralis","display_name":"Trichinella spiralis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/albendazole","display_name":"albendazole","score":0.703000009059906},{"id":"https://openalex.org/keywords/nitrobenzimidazoles","display_name":"nitrobenzimidazoles","score":0.7979999780654907},{"id":"https://openalex.org/keywords/antiparasitic-drugs","display_name":"antiparasitic drugs","score":0.7680000066757202},{"id":"https://openalex.org/keywords/heterocycle-synthesis","display_name":"heterocyclic synthesis","score":0.6499999761581421}],"concepts":[{"id":"https://openalex.org/C2776635100","wikidata":"https://www.wikidata.org/wiki/Q582559","display_name":"Antiprotozoal","level":3,"score":0.9682126045227051},{"id":"https://openalex.org/C2778484023","wikidata":"https://www.wikidata.org/wiki/Q415190","display_name":"Benzimidazole","level":2,"score":0.9402655363082886},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9302414059638977},{"id":"https://openalex.org/C2780378348","wikidata":"https://www.wikidata.org/wiki/Q25351438","display_name":"Ring (chemistry)","level":2,"score":0.6867821216583252},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.6720683574676514},{"id":"https://openalex.org/C24961977","wikidata":"https://www.wikidata.org/wiki/Q225972","display_name":"Bicyclic molecule","level":2,"score":0.4851563572883606},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.39758068323135376},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2144717276096344},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.18598029017448425},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16919288039207458}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000981","descriptor_name":"Antiprotozoal Agents","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D000981","descriptor_name":"Antiprotozoal Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000981","descriptor_name":"Antiprotozoal Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001562","descriptor_name":"Benzimidazoles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011743","descriptor_name":"Pyrimidines","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D011743","descriptor_name":"Pyrimidines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011743","descriptor_name":"Pyrimidines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013237","descriptor_name":"Stereoisomerism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014234","descriptor_name":"Trichinella","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D014235","descriptor_name":"Trichinellosis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016829","descriptor_name":"Giardia lamblia","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.ejmech.2010.09.050","doi":"https://doi.org/10.1016/j.ejmech.2010.09.050","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ejmech.2010.09.050","pdf_url":null,"source":{"id":"https://openalex.org/S4210169613","display_name":"European Journal of Medicinal Chemistry","issn_l":"0223-5234","issn":["0223-5234","1768-3254"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Medicinal Chemistry","raw_type":"journal-article"},{"id":"pmid:20950896","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20950896","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of medicinal chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1969782028","https://openalex.org/W1977134412","https://openalex.org/W1990577135","https://openalex.org/W1992122072","https://openalex.org/W2001919903","https://openalex.org/W2027874140","https://openalex.org/W2036130444","https://openalex.org/W2049655823","https://openalex.org/W2049934743","https://openalex.org/W2063372916","https://openalex.org/W2071063630","https://openalex.org/W2072605023","https://openalex.org/W2089593770","https://openalex.org/W2091370224","https://openalex.org/W2098358868","https://openalex.org/W2108924862","https://openalex.org/W2115544494","https://openalex.org/W2123749893","https://openalex.org/W2137383619","https://openalex.org/W2171192035","https://openalex.org/W2176255757","https://openalex.org/W2314413939","https://openalex.org/W2952396026","https://openalex.org/W4211118011"],"related_works":["https://openalex.org/W2131835191","https://openalex.org/W2089593770","https://openalex.org/W4411338405","https://openalex.org/W2766492676","https://openalex.org/W2099515703","https://openalex.org/W7024908732","https://openalex.org/W2044609406","https://openalex.org/W2599441305","https://openalex.org/W2036130444","https://openalex.org/W2366894456"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}