{"id":"https://openalex.org/W2010528890","doi":"https://doi.org/10.1016/j.amjcard.2006.12.056","title":"Comparison of Outcomes and Usefulness of Carvedilol Across a Spectrum of Left Ventricular Ejection Fractions in Patients With Heart Failure in Clinical Practice","display_name":"Comparison of Outcomes and Usefulness of Carvedilol Across a Spectrum of Left Ventricular Ejection Fractions in Patients With Heart Failure in Clinical Practice","publication_year":2007,"publication_date":"2007-03-14","ids":{"openalex":"https://openalex.org/W2010528890","doi":"https://doi.org/10.1016/j.amjcard.2006.12.056","mag":"2010528890","pmid":"https://pubmed.ncbi.nlm.nih.gov/17478155"},"language":"en","primary_location":{"id":"doi:10.1016/j.amjcard.2006.12.056","doi":"https://doi.org/10.1016/j.amjcard.2006.12.056","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.amjcard.2006.12.056","pdf_url":null,"source":{"id":"https://openalex.org/S185186944","display_name":"The American Journal of Cardiology","issn_l":"0002-9149","issn":["0002-9149","1879-1913"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110081944","display_name":"Barry M. Massie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1315708478","display_name":"San Francisco VA Medical Center","ror":"https://ror.org/049peqw80","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1315708478","https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210125474","https://openalex.org/I4210143381"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Barry M. Massie","raw_affiliation_strings":["Veterans Affairs Medical Center and University of California San Francisco, San Francisco, CA, USA","Veterans Affairs Medical Center and University of California San Francisco, San Francisco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterans Affairs Medical Center and University of California San Francisco, San Francisco, CA, USA","institution_ids":["https://openalex.org/I1315708478","https://openalex.org/I180670191"]},{"raw_affiliation_string":"Veterans Affairs Medical Center and University of California San Francisco, San Francisco","institution_ids":["https://openalex.org/I1315708478","https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110431986","display_name":"Jeanenne Joy Nelson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114143","display_name":"GlaxoSmithKline (United States)","ror":"https://ror.org/025vn3989","country_code":"US","type":"company","lineage":["https://openalex.org/I188950975","https://openalex.org/I4210114143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeanenne J. Nelson","raw_affiliation_strings":["GlaxoSmithKline Pharmaceuticals, Philadelphia, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GlaxoSmithKline Pharmaceuticals, Philadelphia, Pennsylvania","institution_ids":["https://openalex.org/I4210114143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034761484","display_name":"Mary Ann Lukas","orcid":"https://orcid.org/0000-0003-0791-5580","observed_orcids":["https://orcid.org/0000-0003-0791-5580"]},"institutions":[{"id":"https://openalex.org/I4210114143","display_name":"GlaxoSmithKline (United States)","ror":"https://ror.org/025vn3989","country_code":"US","type":"company","lineage":["https://openalex.org/I188950975","https://openalex.org/I4210114143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary Ann Lukas","raw_affiliation_strings":["GlaxoSmithKline Pharmaceuticals, Philadelphia, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GlaxoSmithKline Pharmaceuticals, Philadelphia, Pennsylvania","institution_ids":["https://openalex.org/I4210114143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064906147","display_name":"Barry Greenberg","orcid":"https://orcid.org/0000-0002-6605-9385","observed_orcids":["https://orcid.org/0000-0002-6605-9385"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Barry Greenberg","raw_affiliation_strings":["University of California San Diego, San Diego"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California San Diego, San Diego","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108723471","display_name":"Michael B. Fowler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael B. Fowler","raw_affiliation_strings":["Stanford University Medical Center, Palo Alto, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford University Medical Center, Palo Alto, California","institution_ids":["https://openalex.org/I4210137306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037039739","display_name":"Edward Michael Gilbert","orcid":"https://orcid.org/0000-0002-4298-3645","observed_orcids":["https://orcid.org/0000-0002-4298-3645"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edward M. Gilbert","raw_affiliation_strings":["University of Utah Medical Center, Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Utah Medical Center, Salt Lake City, Utah","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066384461","display_name":"William T. Abraham","orcid":"https://orcid.org/0000-0003-4805-1037","observed_orcids":["https://orcid.org/0000-0003-4805-1037"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William T. Abraham","raw_affiliation_strings":["Ohio State University, School of Medicine, Columbus, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ohio State University, School of Medicine, Columbus, Ohio","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043801735","display_name":"Sandra R. Lottes","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sandra R. Lottes","raw_affiliation_strings":["GlaxoSmithKline Pharmaceuticals, Research Triangle Park, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GlaxoSmithKline Pharmaceuticals, Research Triangle Park, North Carolina","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007220033","display_name":"Joseph A. Franciosa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joseph A. Franciosa","raw_affiliation_strings":["Mt. Sinai School of Medicine and Weill Medical College, Cornell University, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mt. Sinai School of Medicine and Weill Medical College, Cornell University, New York, New York","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I98704320"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5007220033"],"corresponding_institution_ids":["https://openalex.org/I205783295","https://openalex.org/I98704320"],"apc_list":{"value":3380,"currency":"USD","value_usd":3380},"apc_paid":null,"fwci":2.1065,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.87774159,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"99","issue":"9","first_page":"1263","last_page":"1268"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13381","display_name":"Heart rate and cardiovascular health","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carvedilol","display_name":"carvedilol","score":0.9909999966621399},{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.9660000205039978},{"id":"https://openalex.org/keywords/left-ventricular-ejection-fraction","display_name":"left ventricular ejection fraction","score":0.9390000104904175},{"id":"https://openalex.org/keywords/preserved-ejection-fraction","display_name":"preserved ejection fraction","score":0.9139999747276306},{"id":"https://openalex.org/keywords/beta-blocker-therapy","display_name":"beta-blocker therapy","score":0.8569999933242798},{"id":"https://openalex.org/keywords/heart-failure-hospitalization","display_name":"heart failure hospitalization","score":0.972000002861023},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.8330000042915344},{"id":"https://openalex.org/keywords/functional-class","display_name":"functional class","score":0.796999990940094},{"id":"https://openalex.org/keywords/community-based-registry","display_name":"community-based registry","score":0.6570000052452087},{"id":"https://openalex.org/keywords/generalizability-of-trial-results","display_name":"generalizability of trial results","score":0.6470000147819519}],"concepts":[{"id":"https://openalex.org/C2780591200","wikidata":"https://www.wikidata.org/wiki/Q412534","display_name":"Carvedilol","level":3,"score":0.9843741655349731},{"id":"https://openalex.org/C78085059","wikidata":"https://www.wikidata.org/wiki/Q641303","display_name":"Ejection fraction","level":3,"score":0.9369932413101196},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8006457090377808},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.7973006367683411},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7078520059585571},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6959211826324463},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.5338531732559204},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4851139783859253},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.06183239817619324}],"mesh":[{"descriptor_ui":"D000077261","descriptor_name":"Carvedilol","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000319","descriptor_name":"Adrenergic beta-Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002227","descriptor_name":"Carbazoles","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011412","descriptor_name":"Propanolamines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013318","descriptor_name":"Stroke Volume","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.amjcard.2006.12.056","doi":"https://doi.org/10.1016/j.amjcard.2006.12.056","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.amjcard.2006.12.056","pdf_url":null,"source":{"id":"https://openalex.org/S185186944","display_name":"The American Journal of Cardiology","issn_l":"0002-9149","issn":["0002-9149","1879-1913"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Cardiology","raw_type":"journal-article"},{"id":"pmid:17478155","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17478155","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of cardiology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.8899999856948853,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W86665295","https://openalex.org/W1578335350","https://openalex.org/W1993348013","https://openalex.org/W2004733118","https://openalex.org/W2023688706","https://openalex.org/W2025966759","https://openalex.org/W2028617698","https://openalex.org/W2034352665","https://openalex.org/W2046482527","https://openalex.org/W2081017230","https://openalex.org/W2109281287","https://openalex.org/W2119061468","https://openalex.org/W2127254785","https://openalex.org/W2139705590","https://openalex.org/W2155559652","https://openalex.org/W2165842183","https://openalex.org/W2167760816","https://openalex.org/W2168870305","https://openalex.org/W2284554048","https://openalex.org/W2326508838","https://openalex.org/W2498474976"],"related_works":["https://openalex.org/W2135777440","https://openalex.org/W1631417504","https://openalex.org/W2094828316","https://openalex.org/W2068499072","https://openalex.org/W2034352665","https://openalex.org/W2332301557","https://openalex.org/W1990780376","https://openalex.org/W4229915100","https://openalex.org/W1975251531","https://openalex.org/W4242179326"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":6}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}