{"id":"https://openalex.org/W2010511211","doi":"https://doi.org/10.1177/1933719112440049","title":"Trichostatin A and Ascorbic Acid Assist in the Development of Porcine Handmade Cloned Embryos via Different Physiologic Pathways","display_name":"Trichostatin A and Ascorbic Acid Assist in the Development of Porcine Handmade Cloned Embryos via Different Physiologic Pathways","publication_year":2012,"publication_date":"2012-04-26","ids":{"openalex":"https://openalex.org/W2010511211","doi":"https://doi.org/10.1177/1933719112440049","mag":"2010511211","pmid":"https://pubmed.ncbi.nlm.nih.gov/22534331"},"language":"en","primary_location":{"id":"doi:10.1177/1933719112440049","doi":"https://doi.org/10.1177/1933719112440049","is_oa":false,"landing_page_url":"https://doi.org/10.1177/1933719112440049","pdf_url":null,"source":{"id":"https://openalex.org/S68157034","display_name":"Reproductive Sciences","issn_l":"1933-7191","issn":["1933-7191","1933-7205"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033820344","display_name":"Chawalit Siriboon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I162838928","display_name":"National Chung Hsing University","ror":"https://ror.org/05vn3ca78","country_code":"TW","type":"education","lineage":["https://openalex.org/I162838928"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Siriboon Chawalit","raw_affiliation_strings":["Department of Animal Science, National Chung Hsing University, Taichung, Taiwan, Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Science, National Chung Hsing University, Taichung, Taiwan, Republic of China","institution_ids":["https://openalex.org/I162838928"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101728826","display_name":"Ngoc Tan Nguyen","orcid":"https://orcid.org/0000-0001-9529-2787","observed_orcids":["https://orcid.org/0000-0001-9529-2787"]},"institutions":[{"id":"https://openalex.org/I162838928","display_name":"National Chung Hsing University","ror":"https://ror.org/05vn3ca78","country_code":"TW","type":"education","lineage":["https://openalex.org/I162838928"]},{"id":"https://openalex.org/I4405277143","display_name":"Vi\u1ec7n Khoa h\u1ecdc K\u1ef9 thu\u1eadt N\u00f4ng nghi\u1ec7p mi\u1ec1n Nam","ror":"https://ror.org/01m84k711","country_code":"VN","type":"facility","lineage":["https://openalex.org/I4405277143"]}],"countries":["TW","VN"],"is_corresponding":false,"raw_author_name":"Ngoc Tan Nguyen","raw_affiliation_strings":["Agricultural Biotechnology Center, Institute of Agriculture Sciences for Southern Vietnam, Ho Chi Minh City, Vietnam","Department of Animal Science, National Chung Hsing University, Taichung, Taiwan, Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agricultural Biotechnology Center, Institute of Agriculture Sciences for Southern Vietnam, Ho Chi Minh City, Vietnam","institution_ids":["https://openalex.org/I4405277143"]},{"raw_affiliation_string":"Department of Animal Science, National Chung Hsing University, Taichung, Taiwan, Republic of China","institution_ids":["https://openalex.org/I162838928"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008850614","display_name":"Jung\u2010Kai Tseng","orcid":"https://orcid.org/0000-0003-0006-0233","observed_orcids":["https://orcid.org/0000-0003-0006-0233"]},"institutions":[{"id":"https://openalex.org/I91279580","display_name":"Chung Shan Medical University","ror":"https://ror.org/059ryjv25","country_code":"TW","type":"education","lineage":["https://openalex.org/I91279580"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Jung-Kai Tseng","raw_affiliation_strings":["School of Optometry, Chung Shan Medical University, Taichung, Taiwan, Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Optometry, Chung Shan Medical University, Taichung, Taiwan, Republic of China","institution_ids":["https://openalex.org/I91279580"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110181577","display_name":"Neng\u2010Wen Lo","orcid":"https://orcid.org/0000-0003-0070-9362","observed_orcids":["https://orcid.org/0000-0003-0070-9362"]},"institutions":[{"id":"https://openalex.org/I169090423","display_name":"Tunghai University","ror":"https://ror.org/00zhvdn11","country_code":"TW","type":"education","lineage":["https://openalex.org/I169090423"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Neng-Wen Lo","raw_affiliation_strings":["Department of Animal Science and Biotechnology, Tunghai University, Taichung, Taiwan, Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Science and Biotechnology, Tunghai University, Taichung, Taiwan, Republic of China","institution_ids":["https://openalex.org/I169090423"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060837534","display_name":"Ching\u2010Fu Tu","orcid":"https://orcid.org/0000-0001-5142-7264","observed_orcids":["https://orcid.org/0000-0001-5142-7264"]},"institutions":[{"id":"https://openalex.org/I4210165564","display_name":"Animal Technology Institute Taiwan","ror":"https://ror.org/05v4bk714","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210165564"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Ching-Fu Tu","raw_affiliation_strings":["Animal Technology Institute Taiwan, Ding-Pu LII, Chunan, Miaoli, Taiwan, Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Animal Technology Institute Taiwan, Ding-Pu LII, Chunan, Miaoli, Taiwan, Republic of China","institution_ids":["https://openalex.org/I4210165564"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016050168","display_name":"Jyh-Cherng Ju","orcid":"https://orcid.org/0000-0003-3987-8200","observed_orcids":["https://orcid.org/0000-0003-3987-8200"]},"institutions":[{"id":"https://openalex.org/I162838928","display_name":"National Chung Hsing University","ror":"https://ror.org/05vn3ca78","country_code":"TW","type":"education","lineage":["https://openalex.org/I162838928"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Jyh-Cherng Ju","raw_affiliation_strings":["Agricultural Biotechnology Center, National Chung Hsing University, 250 Kuokuang Road, 402, Taichung, Taiwan, ROC","Department of Animal Science, National Chung Hsing University, Taichung, Taiwan, Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agricultural Biotechnology Center, National Chung Hsing University, 250 Kuokuang Road, 402, Taichung, Taiwan, ROC","institution_ids":["https://openalex.org/I162838928"]},{"raw_affiliation_string":"Department of Animal Science, National Chung Hsing University, Taichung, Taiwan, Republic of China","institution_ids":["https://openalex.org/I162838928"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5016050168"],"corresponding_institution_ids":["https://openalex.org/I162838928"],"apc_list":{"value":3090,"currency":"USD","value_usd":3090},"apc_paid":null,"fwci":0.8804,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.71658409,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"19","issue":"9","first_page":"976","last_page":"986"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12929","display_name":"Animal Genetics and Reproduction","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12929","display_name":"Animal Genetics and Reproduction","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.005799999926239252,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trichostatin-a","display_name":"trichostatin A","score":0.9789999723434448},{"id":"https://openalex.org/keywords/vitamin-c","display_name":"vitamin C","score":1.0},{"id":"https://openalex.org/keywords/porcine-embryos","display_name":"porcine embryos","score":0.8600000143051147},{"id":"https://openalex.org/keywords/somatic-cell-nuclear-transfer","display_name":"somatic cell nuclear transfer","score":0.7540000081062317},{"id":"https://openalex.org/keywords/histone-acetylation","display_name":"histone acetylation","score":0.8629999756813049},{"id":"https://openalex.org/keywords/blastocyst-development","display_name":"blastocyst development","score":0.8799999952316284},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.7070000171661377},{"id":"https://openalex.org/keywords/cellular-reprogramming","display_name":"cellular reprogramming","score":0.7260000109672546},{"id":"https://openalex.org/keywords/antioxidant-pathways","display_name":"antioxidant pathways","score":0.7070000171661377},{"id":"https://openalex.org/keywords/epigenetic-reprogramming","display_name":"epigenetic reprogramming","score":0.7300000190734863}],"concepts":[{"id":"https://openalex.org/C2778177303","wikidata":"https://www.wikidata.org/wiki/Q227717","display_name":"Blastocyst","level":4,"score":0.9270824193954468},{"id":"https://openalex.org/C2777865847","wikidata":"https://www.wikidata.org/wiki/Q425894","display_name":"Trichostatin A","level":5,"score":0.8921186327934265},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.7669574022293091},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.6554532051086426},{"id":"https://openalex.org/C2986274086","wikidata":"https://www.wikidata.org/wiki/Q199678","display_name":"Ascorbic acid","level":2,"score":0.6473178267478943},{"id":"https://openalex.org/C77255625","wikidata":"https://www.wikidata.org/wiki/Q402093","display_name":"Reprogramming","level":3,"score":0.5892734527587891},{"id":"https://openalex.org/C14814345","wikidata":"https://www.wikidata.org/wiki/Q589646","display_name":"Theriogenology","level":5,"score":0.503060519695282},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.48948729038238525},{"id":"https://openalex.org/C2776202225","wikidata":"https://www.wikidata.org/wiki/Q3569101","display_name":"Histone deacetylase inhibitor","level":5,"score":0.4251784086227417},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4165509343147278},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3911910653114319},{"id":"https://openalex.org/C2779335785","wikidata":"https://www.wikidata.org/wiki/Q5370217","display_name":"Embryo culture","level":4,"score":0.3763844966888428},{"id":"https://openalex.org/C2778305200","wikidata":"https://www.wikidata.org/wiki/Q174378","display_name":"Histone deacetylase","level":4,"score":0.2647671401500702},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.20052725076675415},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18823754787445068},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14886975288391113},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.096793532371521},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.04760679602622986},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001205","descriptor_name":"Ascorbic Acid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006877","descriptor_name":"Hydroxamic Acids","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019976","descriptor_name":"Cloning, Organism","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D046149","descriptor_name":"Embryo Culture Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D047108","descriptor_name":"Embryonic Development","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D047108","descriptor_name":"Embryonic Development","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1177/1933719112440049","doi":"https://doi.org/10.1177/1933719112440049","is_oa":false,"landing_page_url":"https://doi.org/10.1177/1933719112440049","pdf_url":null,"source":{"id":"https://openalex.org/S68157034","display_name":"Reproductive Sciences","issn_l":"1933-7191","issn":["1933-7191","1933-7205"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive Sciences","raw_type":"journal-article"},{"id":"pmid:22534331","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22534331","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive sciences (Thousand Oaks, Calif.)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321040","display_name":"National Science Council","ror":"https://ror.org/02kv4zf79"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W1487014009","https://openalex.org/W1585827177","https://openalex.org/W1916885428","https://openalex.org/W1992525863","https://openalex.org/W1993205220","https://openalex.org/W2000625991","https://openalex.org/W2003366415","https://openalex.org/W2003701368","https://openalex.org/W2012206386","https://openalex.org/W2015554554","https://openalex.org/W2025239052","https://openalex.org/W2028320284","https://openalex.org/W2035529579","https://openalex.org/W2037292900","https://openalex.org/W2043585717","https://openalex.org/W2043952117","https://openalex.org/W2047220698","https://openalex.org/W2049329097","https://openalex.org/W2049431525","https://openalex.org/W2054314939","https://openalex.org/W2057430589","https://openalex.org/W2064890605","https://openalex.org/W2067789711","https://openalex.org/W2068022934","https://openalex.org/W2091236246","https://openalex.org/W2092629964","https://openalex.org/W2093155802","https://openalex.org/W2100016959","https://openalex.org/W2104106827","https://openalex.org/W2105718307","https://openalex.org/W2106844301","https://openalex.org/W2119781626","https://openalex.org/W2121871605","https://openalex.org/W2125726311","https://openalex.org/W2126657029","https://openalex.org/W2130603658","https://openalex.org/W2130631511","https://openalex.org/W2131278882","https://openalex.org/W2141856502","https://openalex.org/W2148125367","https://openalex.org/W2150696636","https://openalex.org/W2159547037","https://openalex.org/W2166649689","https://openalex.org/W2166874810","https://openalex.org/W2168825044","https://openalex.org/W2330843862"],"related_works":["https://openalex.org/W2129601188","https://openalex.org/W2159547037","https://openalex.org/W2312611421","https://openalex.org/W2130998515","https://openalex.org/W1938412091","https://openalex.org/W2002927505","https://openalex.org/W1993634243","https://openalex.org/W4408201703","https://openalex.org/W2405235593","https://openalex.org/W1970289162"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":5},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}