{"id":"https://openalex.org/W2010444010","doi":"https://doi.org/10.1038/nrc755","title":"Emerging molecular markers of cancer","display_name":"Emerging molecular markers of cancer","publication_year":2002,"publication_date":"2002-03-01","ids":{"openalex":"https://openalex.org/W2010444010","doi":"https://doi.org/10.1038/nrc755","mag":"2010444010","pmid":"https://pubmed.ncbi.nlm.nih.gov/11990857"},"language":"en","primary_location":{"id":"doi:10.1038/nrc755","doi":"https://doi.org/10.1038/nrc755","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nrc755","pdf_url":null,"source":{"id":"https://openalex.org/S160464432","display_name":"Nature reviews. Cancer","issn_l":"1474-175X","issn":["1474-175X","1474-1768"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Reviews Cancer","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109152183","display_name":"David Sidransky","orcid":"https://orcid.org/0000-0003-4178-2072","observed_orcids":["https://orcid.org/0000-0003-4178-2072"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David Sidransky","raw_affiliation_strings":["The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. dsidrans@jhmi.edu","[The Johns Hopkins University School of Medicine, Baltimore, USA]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. dsidrans@jhmi.edu","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]},{"raw_affiliation_string":"[The Johns Hopkins University School of Medicine, Baltimore, USA]","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5109152183"],"corresponding_institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"],"apc_list":null,"apc_paid":null,"fwci":3.7311,"has_fulltext":false,"cited_by_count":660,"citation_normalized_percentile":{"value":0.95095949,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"2","issue":"3","first_page":"210","last_page":"219"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/molecular-markers","display_name":"molecular markers","score":0.8169999718666077},{"id":"https://openalex.org/keywords/tumor-markers","display_name":"tumor markers","score":0.9079999923706055},{"id":"https://openalex.org/keywords/cancer-detection","display_name":"cancer detection","score":0.7680000066757202},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.8209999799728394},{"id":"https://openalex.org/keywords/disease-progression-monitoring","display_name":"disease progression monitoring","score":0.9240000247955322},{"id":"https://openalex.org/keywords/treatment-response-monitoring","display_name":"treatment response monitoring","score":0.8980000019073486},{"id":"https://openalex.org/keywords/gene-expression-changes","display_name":"gene expression changes","score":0.7319999933242798},{"id":"https://openalex.org/keywords/protein-structure-function-relationship","display_name":"protein structure-function relationship","score":0.6230000257492065},{"id":"https://openalex.org/keywords/clinical-implementation","display_name":"clinical implementation","score":0.5699999928474426}],"concepts":[{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6044538617134094},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46060094237327576},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4498981535434723},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4237155616283417},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.42295265197753906},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.41787800192832947},{"id":"https://openalex.org/C2777160741","wikidata":"https://www.wikidata.org/wiki/Q2311855","display_name":"Molecular marker","level":3,"score":0.41225630044937134},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3558778762817383},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2633371949195862},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25603100657463074}],"mesh":[{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005819","descriptor_name":"Genetic Markers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/nrc755","doi":"https://doi.org/10.1038/nrc755","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nrc755","pdf_url":null,"source":{"id":"https://openalex.org/S160464432","display_name":"Nature reviews. Cancer","issn_l":"1474-175X","issn":["1474-175X","1474-1768"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Reviews Cancer","raw_type":"journal-article"},{"id":"pmid:11990857","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11990857","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature reviews. Cancer","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":98,"referenced_works":["https://openalex.org/W161377529","https://openalex.org/W161630099","https://openalex.org/W254716823","https://openalex.org/W1500427884","https://openalex.org/W1573764197","https://openalex.org/W1583721197","https://openalex.org/W1592187645","https://openalex.org/W1596363943","https://openalex.org/W1602204638","https://openalex.org/W1618318544","https://openalex.org/W1626428648","https://openalex.org/W1633962291","https://openalex.org/W1639620410","https://openalex.org/W1658127082","https://openalex.org/W1748734394","https://openalex.org/W1755134370","https://openalex.org/W1782090758","https://openalex.org/W1798089528","https://openalex.org/W1802480460","https://openalex.org/W1834558432","https://openalex.org/W1849446486","https://openalex.org/W1852564520","https://openalex.org/W1864823043","https://openalex.org/W1924090634","https://openalex.org/W1929295557","https://openalex.org/W1939667038","https://openalex.org/W1968331471","https://openalex.org/W1968904767","https://openalex.org/W1977706798","https://openalex.org/W1978711255","https://openalex.org/W1979610420","https://openalex.org/W1988145726","https://openalex.org/W1990423774","https://openalex.org/W1990720034","https://openalex.org/W1994465394","https://openalex.org/W1995134833","https://openalex.org/W1998175281","https://openalex.org/W2001258296","https://openalex.org/W2004891705","https://openalex.org/W2004933942","https://openalex.org/W2010888033","https://openalex.org/W2011820948","https://openalex.org/W2015213611","https://openalex.org/W2021930193","https://openalex.org/W2022346160","https://openalex.org/W2027913086","https://openalex.org/W2030307914","https://openalex.org/W2030958510","https://openalex.org/W2032799811","https://openalex.org/W2036946548","https://openalex.org/W2043201861","https://openalex.org/W2049486026","https://openalex.org/W2054823635","https://openalex.org/W2058499147","https://openalex.org/W2058658262","https://openalex.org/W2061805562","https://openalex.org/W2068380327","https://openalex.org/W2068746221","https://openalex.org/W2069786312","https://openalex.org/W2071034864","https://openalex.org/W2073378332","https://openalex.org/W2075865556","https://openalex.org/W2076791242","https://openalex.org/W2079378073","https://openalex.org/W2082539367","https://openalex.org/W2083741208","https://openalex.org/W2090290582","https://openalex.org/W2095356554","https://openalex.org/W2097335559","https://openalex.org/W2098178758","https://openalex.org/W2110511887","https://openalex.org/W2112028665","https://openalex.org/W2116846790","https://openalex.org/W2120396343","https://openalex.org/W2123244768","https://openalex.org/W2124133870","https://openalex.org/W2130171168","https://openalex.org/W2133973332","https://openalex.org/W2134389439","https://openalex.org/W2136826185","https://openalex.org/W2142191611","https://openalex.org/W2148805136","https://openalex.org/W2149767124","https://openalex.org/W2156643308","https://openalex.org/W2160658234","https://openalex.org/W2161252269","https://openalex.org/W2166075028","https://openalex.org/W2169453618","https://openalex.org/W2169991116","https://openalex.org/W2172175430","https://openalex.org/W2336058699","https://openalex.org/W2339671919","https://openalex.org/W2407770428","https://openalex.org/W2415523424","https://openalex.org/W2418089386","https://openalex.org/W2419822127","https://openalex.org/W2444206556","https://openalex.org/W4213387068"],"related_works":["https://openalex.org/W2791607800","https://openalex.org/W4411294077","https://openalex.org/W3138341000","https://openalex.org/W2138591706","https://openalex.org/W153306220","https://openalex.org/W2083559664","https://openalex.org/W2181674734","https://openalex.org/W2118898390","https://openalex.org/W7100492944","https://openalex.org/W2401704515"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":14},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":18},{"year":2020,"cited_by_count":19},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":16},{"year":2017,"cited_by_count":18},{"year":2016,"cited_by_count":31},{"year":2015,"cited_by_count":33},{"year":2014,"cited_by_count":33},{"year":2013,"cited_by_count":34},{"year":2012,"cited_by_count":36}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}