{"id":"https://openalex.org/W2010427955","doi":"https://doi.org/10.1007/s10096-004-1136-2","title":"In vitro activity of amphotericin B, fluconazole and voriconazole against 162 Cryptococcus neoformans isolates from Africa and Cambodia","display_name":"In vitro activity of amphotericin B, fluconazole and voriconazole against 162 Cryptococcus neoformans isolates from Africa and Cambodia","publication_year":2004,"publication_date":"2004-05-12","ids":{"openalex":"https://openalex.org/W2010427955","doi":"https://doi.org/10.1007/s10096-004-1136-2","mag":"2010427955","pmid":"https://pubmed.ncbi.nlm.nih.gov/15141336"},"language":"en","primary_location":{"id":"doi:10.1007/s10096-004-1136-2","doi":"https://doi.org/10.1007/s10096-004-1136-2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10096-004-1136-2","pdf_url":null,"source":{"id":"https://openalex.org/S130127385","display_name":"European Journal of Clinical Microbiology & Infectious Diseases","issn_l":"0934-9723","issn":["0934-9723","1435-4373"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical Microbiology & Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110027429","display_name":"J. Chandenier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210095477","display_name":"Centre Hospitalier Universitaire de Tours","ror":"https://ror.org/00jpq0w62","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210095477"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"J. Chandenier","raw_affiliation_strings":["Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, 37000 Tours, France. jac-bri.chandenier@wanadoo.fr","Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, Tours, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, 37000 Tours, France. jac-bri.chandenier@wanadoo.fr","institution_ids":["https://openalex.org/I4210095477"]},{"raw_affiliation_string":"Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, Tours, France","institution_ids":["https://openalex.org/I4210095477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010616137","display_name":"Koffi Daho Adoubryn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210095477","display_name":"Centre Hospitalier Universitaire de Tours","ror":"https://ror.org/00jpq0w62","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210095477"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"K. D. Adou-Bryn","raw_affiliation_strings":["Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, 37000, Tours, France","Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, Tours, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, 37000, Tours, France","institution_ids":["https://openalex.org/I4210095477"]},{"raw_affiliation_string":"Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, Tours, France","institution_ids":["https://openalex.org/I4210095477"]}]},{"author_position":"middle","author":{"id":null,"display_name":"C. Douchet","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210095477","display_name":"Centre Hospitalier Universitaire de Tours","ror":"https://ror.org/00jpq0w62","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210095477"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C. Douchet","raw_affiliation_strings":["Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, 37000, Tours, France","Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, Tours, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, 37000, Tours, France","institution_ids":["https://openalex.org/I4210095477"]},{"raw_affiliation_string":"Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, Tours, France","institution_ids":["https://openalex.org/I4210095477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113518581","display_name":"B. Sar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210135788","display_name":"Institut Pasteur du Cambodge","ror":"https://ror.org/03ht2dx40","country_code":"KH","type":"facility","lineage":["https://openalex.org/I4210135788"]}],"countries":["KH"],"is_corresponding":false,"raw_author_name":"B. Sar","raw_affiliation_strings":["Institut Pasteur du Cambodge, Phnom Penh, Cambodia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pasteur du Cambodge, Phnom Penh, Cambodia","institution_ids":["https://openalex.org/I4210135788"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110219574","display_name":"Maryvonne Kombila","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Kombila","raw_affiliation_strings":["D\u00e9partement de Parasitologie-Mycologie-M\u00e9decine Tropicale, FMSS, BP 4009, Libreville, Gabon","D\u00e9partement de Parasitologie-Mycologie-M\u00e9decine Tropicale, FMSS, Libreville, Gabon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"D\u00e9partement de Parasitologie-Mycologie-M\u00e9decine Tropicale, FMSS, BP 4009, Libreville, Gabon","institution_ids":[]},{"raw_affiliation_string":"D\u00e9partement de Parasitologie-Mycologie-M\u00e9decine Tropicale, FMSS, Libreville, Gabon","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068797645","display_name":"D. Swinne","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158280","display_name":"Institut Scientifique de Sant\u00e9 Publique","ror":"https://ror.org/04ws26165","country_code":"BE","type":"facility","lineage":["https://openalex.org/I4210158280"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"D. Swinne","raw_affiliation_strings":["Institut Scientifique de Sant\u00e9 Publique-Mycologie, Wytsman Street, 141050, Brussels, Belgium","Institut Scientifique de Sant\u00e9 Publique-Mycologie, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Scientifique de Sant\u00e9 Publique-Mycologie, Wytsman Street, 141050, Brussels, Belgium","institution_ids":["https://openalex.org/I4210158280"]},{"raw_affiliation_string":"Institut Scientifique de Sant\u00e9 Publique-Mycologie, Brussels, Belgium","institution_ids":["https://openalex.org/I4210158280"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055786550","display_name":"M. Th\u00e9rizol\u2010Ferly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210095477","display_name":"Centre Hospitalier Universitaire de Tours","ror":"https://ror.org/00jpq0w62","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210095477"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"M. Th\ufffdrizol-Ferly","raw_affiliation_strings":["Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, Tours, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, Tours, France","institution_ids":["https://openalex.org/I4210095477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028418709","display_name":"Yves Buisson","orcid":"https://orcid.org/0000-0003-0301-4611","observed_orcids":["https://orcid.org/0000-0003-0301-4611"]},"institutions":[{"id":"https://openalex.org/I4210135788","display_name":"Institut Pasteur du Cambodge","ror":"https://ror.org/03ht2dx40","country_code":"KH","type":"facility","lineage":["https://openalex.org/I4210135788"]}],"countries":["KH"],"is_corresponding":false,"raw_author_name":"Y. Buisson","raw_affiliation_strings":["Institut Pasteur du Cambodge, Phnom Penh, Cambodia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pasteur du Cambodge, Phnom Penh, Cambodia","institution_ids":["https://openalex.org/I4210135788"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062353866","display_name":"D Richard-Lenoble","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210095477","display_name":"Centre Hospitalier Universitaire de Tours","ror":"https://ror.org/00jpq0w62","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210095477"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"D. Richard-Lenoble","raw_affiliation_strings":["Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, 37000, Tours, France","Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, Tours, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, 37000, Tours, France","institution_ids":["https://openalex.org/I4210095477"]},{"raw_affiliation_string":"Service de Parasitologie-Mycologie-M\u00e9decine Tropicale, Centre Hospitalier et Universitaire, Tours, France","institution_ids":["https://openalex.org/I4210095477"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5110027429"],"corresponding_institution_ids":["https://openalex.org/I4210095477"],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":null,"fwci":2.5288,"has_fulltext":false,"cited_by_count":46,"citation_normalized_percentile":{"value":0.88447852,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"23","issue":"6","first_page":"506","last_page":"508"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11037","display_name":"Fungal Infections and Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11037","display_name":"Fungal Infections and Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cryptococcus-neoformans","display_name":"Cryptococcus neoformans","score":1.0},{"id":"https://openalex.org/keywords/cryptococcosis","display_name":"cryptococcosis","score":0.9810000061988831},{"id":"https://openalex.org/keywords/amphotericin-b","display_name":"amphotericin B","score":0.8949999809265137},{"id":"https://openalex.org/keywords/fluconazole","display_name":"fluconazole","score":1.0},{"id":"https://openalex.org/keywords/voriconazole","display_name":"voriconazole","score":1.0},{"id":"https://openalex.org/keywords/antifungal-susceptibility","display_name":"antifungal susceptibility","score":0.9539999961853027},{"id":"https://openalex.org/keywords/in-vitro-susceptibility-testing","display_name":"in vitro susceptibility testing","score":0.718999981880188},{"id":"https://openalex.org/keywords/e-test","display_name":"E-test","score":0.9660000205039978},{"id":"https://openalex.org/keywords/tropical-fungal-infections","display_name":"tropical fungal infections","score":0.5870000123977661},{"id":"https://openalex.org/keywords/african-isolates","display_name":"African isolates","score":0.7699999809265137}],"concepts":[{"id":"https://openalex.org/C2780690907","wikidata":"https://www.wikidata.org/wiki/Q412236","display_name":"Voriconazole","level":3,"score":0.9651405811309814},{"id":"https://openalex.org/C2777893358","wikidata":"https://www.wikidata.org/wiki/Q131924","display_name":"Cryptococcus neoformans","level":2,"score":0.9112122058868408},{"id":"https://openalex.org/C2779629538","wikidata":"https://www.wikidata.org/wiki/Q412223","display_name":"Amphotericin B","level":3,"score":0.8651749491691589},{"id":"https://openalex.org/C2780651595","wikidata":"https://www.wikidata.org/wiki/Q411478","display_name":"Fluconazole","level":3,"score":0.8186076879501343},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6865516901016235},{"id":"https://openalex.org/C2779413141","wikidata":"https://www.wikidata.org/wiki/Q1470140","display_name":"Cryptococcosis","level":2,"score":0.5853791832923889},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49630671739578247},{"id":"https://openalex.org/C190139176","wikidata":"https://www.wikidata.org/wiki/Q598976","display_name":"Medical microbiology","level":2,"score":0.4562867283821106},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.412134051322937},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.3797783851623535},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000349","descriptor_name":"Africa","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D000666","descriptor_name":"Amphotericin B","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002160","descriptor_name":"Cambodia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D003453","descriptor_name":"Cryptococcosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D003453","descriptor_name":"Cryptococcosis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D003455","descriptor_name":"Cryptococcus neoformans","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D003455","descriptor_name":"Cryptococcus neoformans","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D003906","descriptor_name":"Developing Countries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011743","descriptor_name":"Pyrimidines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D012494","descriptor_name":"Sampling Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014230","descriptor_name":"Triazoles","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015725","descriptor_name":"Fluconazole","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025141","descriptor_name":"Drug Resistance, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065819","descriptor_name":"Voriconazole","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s10096-004-1136-2","doi":"https://doi.org/10.1007/s10096-004-1136-2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10096-004-1136-2","pdf_url":null,"source":{"id":"https://openalex.org/S130127385","display_name":"European Journal of Clinical Microbiology & Infectious Diseases","issn_l":"0934-9723","issn":["0934-9723","1435-4373"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical Microbiology & Infectious Diseases","raw_type":"journal-article"},{"id":"pmid:15141336","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15141336","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307765","display_name":"Pfizer","ror":"https://ror.org/01xdqrp08"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W2837670","https://openalex.org/W253179561","https://openalex.org/W1565636659","https://openalex.org/W1987013433","https://openalex.org/W2032556038","https://openalex.org/W2073079266","https://openalex.org/W2110229748","https://openalex.org/W2110613363","https://openalex.org/W2118836068","https://openalex.org/W2121535664","https://openalex.org/W2121959809","https://openalex.org/W2125933984","https://openalex.org/W2147038307","https://openalex.org/W2159305177","https://openalex.org/W2162874187"],"related_works":["https://openalex.org/W2121535664","https://openalex.org/W2909356057","https://openalex.org/W2140520257","https://openalex.org/W7099513669","https://openalex.org/W2122020478","https://openalex.org/W2128866567","https://openalex.org/W4408494595","https://openalex.org/W2005422198","https://openalex.org/W2155163553","https://openalex.org/W2079330813"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":5},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}