{"id":"https://openalex.org/W2010417028","doi":"https://doi.org/10.1097/00005373-197802000-00007","title":"Plasma Lipids, Coagulation Factors, and Fibrin Formation after Severe Multiple Trauma, and in Adult Respiratory Distress Syndrome","display_name":"Plasma Lipids, Coagulation Factors, and Fibrin Formation after Severe Multiple Trauma, and in Adult Respiratory Distress Syndrome","publication_year":1978,"publication_date":"1978-02-01","ids":{"openalex":"https://openalex.org/W2010417028","doi":"https://doi.org/10.1097/00005373-197802000-00007","mag":"2010417028","pmid":"https://pubmed.ncbi.nlm.nih.gov/633418"},"language":"en","primary_location":{"id":"doi:10.1097/00005373-197802000-00007","doi":"https://doi.org/10.1097/00005373-197802000-00007","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00005373-197802000-00007","pdf_url":null,"source":{"id":"https://openalex.org/S2312674","display_name":"The Journal of Trauma: Injury, Infection, and Critical Care","issn_l":"0022-5282","issn":["0022-5282","1529-8809"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Trauma: Injury, Infection, and Critical Care","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108503481","display_name":"F. Kunz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"F KUNZ","raw_affiliation_strings":["the Departments of Internal Medicine, Anaesthesiology, and Neurology of the University of Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Departments of Internal Medicine, Anaesthesiology, and Neurology of the University of Innsbruck, Austria","institution_ids":["https://openalex.org/I190249584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110330890","display_name":"Heide H\ufffdrtnagl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"H H??RTNAGL","raw_affiliation_strings":["the Departments of Internal Medicine, Anaesthesiology, and Neurology of the University of Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Departments of Internal Medicine, Anaesthesiology, and Neurology of the University of Innsbruck, Austria","institution_ids":["https://openalex.org/I190249584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051774132","display_name":"G. Kroesen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"G KROESEN","raw_affiliation_strings":["the Departments of Internal Medicine, Anaesthesiology, and Neurology of the University of Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Departments of Internal Medicine, Anaesthesiology, and Neurology of the University of Innsbruck, Austria","institution_ids":["https://openalex.org/I190249584"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048406014","display_name":"Erik Rumpl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"E RUMPL","raw_affiliation_strings":["the Departments of Internal Medicine, Anaesthesiology, and Neurology of the University of Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Departments of Internal Medicine, Anaesthesiology, and Neurology of the University of Innsbruck, Austria","institution_ids":["https://openalex.org/I190249584"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I190249584"],"apc_list":null,"apc_paid":null,"fwci":0.7983,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.68325792,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"18","issue":"2","first_page":"115","last_page":"120"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11116","display_name":"Trauma, Hemostasis, Coagulopathy, Resuscitation","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11116","display_name":"Trauma, Hemostasis, Coagulopathy, Resuscitation","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.01730000041425228,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plasma-lipids","display_name":"plasma lipids","score":0.8389999866485596},{"id":"https://openalex.org/keywords/coagulation-factors","display_name":"coagulation factors","score":0.8349999785423279},{"id":"https://openalex.org/keywords/fibrin-formation","display_name":"fibrin formation","score":0.9890000224113464},{"id":"https://openalex.org/keywords/polytrauma","display_name":"polytrauma","score":0.8059999942779541},{"id":"https://openalex.org/keywords/acute-respiratory-distress-syndrome","display_name":"acute respiratory distress syndrome","score":0.9860000014305115},{"id":"https://openalex.org/keywords/fat-embolism-syndrome","display_name":"fat embolism syndrome","score":0.9769999980926514},{"id":"https://openalex.org/keywords/fibrinolysis-inhibition","display_name":"fibrinolysis inhibition","score":0.8059999942779541},{"id":"https://openalex.org/keywords/free-cholesterol","display_name":"free cholesterol","score":0.6819999814033508},{"id":"https://openalex.org/keywords/cholesteryl-esters","display_name":"cholesterol esters","score":0.9679999947547913},{"id":"https://openalex.org/keywords/phospholipids","display_name":"phospholipids","score":0.8870000243186951},{"id":"https://openalex.org/keywords/lysophosphatidylcholine","display_name":"lysophosphatidylcholine","score":0.9589999914169312},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.5619999766349792}],"concepts":[{"id":"https://openalex.org/C141983124","wikidata":"https://www.wikidata.org/wiki/Q188008","display_name":"Respiratory distress","level":2,"score":0.8145840167999268},{"id":"https://openalex.org/C54173615","wikidata":"https://www.wikidata.org/wiki/Q27205","display_name":"Fibrin","level":2,"score":0.7871571779251099},{"id":"https://openalex.org/C2776825266","wikidata":"https://www.wikidata.org/wiki/Q1410794","display_name":"Fibrinolysis","level":2,"score":0.7719783186912537},{"id":"https://openalex.org/C2778382381","wikidata":"https://www.wikidata.org/wiki/Q179217","display_name":"Coagulation","level":2,"score":0.6988224387168884},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5066743493080139},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.4853011965751648},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.48372963070869446},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.4672197103500366},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.44159165024757385},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.436576783657074},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.29355934262275696},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.23348969221115112}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001779","descriptor_name":"Blood Coagulation Factors","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002788","descriptor_name":"Cholesterol Esters","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005337","descriptor_name":"Fibrin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008074","descriptor_name":"Lipoproteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008244","descriptor_name":"Lysophosphatidylcholines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010743","descriptor_name":"Phospholipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012128","descriptor_name":"Respiratory Distress Syndrome","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D012128","descriptor_name":"Respiratory Distress Syndrome","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D014947","descriptor_name":"Wounds and Injuries","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/00005373-197802000-00007","doi":"https://doi.org/10.1097/00005373-197802000-00007","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00005373-197802000-00007","pdf_url":null,"source":{"id":"https://openalex.org/S2312674","display_name":"The Journal of Trauma: Injury, Infection, and Critical Care","issn_l":"0022-5282","issn":["0022-5282","1529-8809"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Trauma: Injury, Infection, and Critical Care","raw_type":"journal-article"},{"id":"pmid:633418","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/633418","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of trauma","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1987694459","https://openalex.org/W2159495470","https://openalex.org/W1993018542","https://openalex.org/W2063420010","https://openalex.org/W3113519831","https://openalex.org/W2044650474","https://openalex.org/W2414271850","https://openalex.org/W2029224740","https://openalex.org/W2418155331","https://openalex.org/W3120018770"],"abstract_inverted_index":{"Following":[0],"severe":[1,113],"multiple":[2,73],"trauma,":[3],"decreases":[4],"were":[5,57,92],"observed":[6],"in":[7,23,60,95,100,107,137],"a)":[8,49],"Free":[9],"cholesterol,":[10],"b)":[11,86],"Cholesteryl":[12],"esters,":[13],"c)":[14],"Total":[15],"phospholipids,":[16],"and":[17,66],"d)":[18],"Lysolecithin.":[19],"Comparatively":[20],"slight":[21],"changes":[22,106],"coagulation":[24],"parameters":[25],"did":[26],"not":[27],"differ":[28],"regardless":[29],"of":[30,82,118,140],"whether":[31],"pulmonary":[32,77],"complications":[33],"developed.":[34],"In":[35],"contrast,":[36],"increased":[37,123],"fibrin":[38],"lipid":[39,84,110],"complexing":[40],"was":[41,80],"more":[42],"closely":[43],"correlated":[44],"with":[45,55,62,72,90,122],"clinical":[46],"data,":[47],"because:":[48],"Plasmatic":[50,87],"lipids,":[51],"particularly":[52],"triglycerides":[53,88],"complexed":[54,89],"fibrins,":[56],"elevated":[58],"severalfold":[59],"patients":[61,75,96],"adult":[63],"respiratory":[64,142],"distress":[65,143],"fat":[67],"embolism":[68],"syndromes":[69],"when":[70],"compared":[71],"trauma":[74,114],"without":[76],"complications.":[78],"This":[79,130],"independent":[81],"plasma":[83,109],"levels.":[85],"fibrins":[91],"significantly":[93],"higher":[94],"who":[97,102],"died":[98],"than":[99],"those":[101],"survived.":[103],"The":[104],"considerable":[105],"the":[108,116,138],"pattern":[111],"following":[112],"suggest":[115],"presence":[117],"an":[119],"abnormal":[120],"lipoprotein":[121],"affinity":[124],"to":[125],"fibrin,":[126],"thereby":[127],"inhibiting":[128],"fibrinolysis.":[129],"might":[131],"well":[132],"be":[133],"one":[134],"pathogenic":[135],"mechanism":[136],"development":[139],"post-traumatic":[141],"syndrome.":[144]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}