{"id":"https://openalex.org/W2010330435","doi":"https://doi.org/10.1007/s12010-014-1003-2","title":"Cloning and Expression Characteristics of the Notch-Associated Gene BmE(spl)m\u03b3 from Silkworm, Bombyx mori","display_name":"Cloning and Expression Characteristics of the Notch-Associated Gene BmE(spl)m\u03b3 from Silkworm, Bombyx mori","publication_year":2014,"publication_date":"2014-06-10","ids":{"openalex":"https://openalex.org/W2010330435","doi":"https://doi.org/10.1007/s12010-014-1003-2","mag":"2010330435","pmid":"https://pubmed.ncbi.nlm.nih.gov/24916802"},"language":"en","primary_location":{"id":"doi:10.1007/s12010-014-1003-2","doi":"https://doi.org/10.1007/s12010-014-1003-2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12010-014-1003-2","pdf_url":null,"source":{"id":"https://openalex.org/S153285774","display_name":"Applied Biochemistry and Biotechnology","issn_l":"0273-2289","issn":["0273-2289","1559-0291"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied Biochemistry and Biotechnology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100661315","display_name":"Min Liu","orcid":"https://orcid.org/0000-0001-7095-1344","observed_orcids":["https://orcid.org/0000-0001-7095-1344"]},"institutions":[{"id":"https://openalex.org/I1328775524","display_name":"Zhejiang Sci-Tech University","ror":"https://ror.org/03893we55","country_code":"CN","type":"education","lineage":["https://openalex.org/I1328775524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Liu","raw_affiliation_strings":["College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","institution_ids":["https://openalex.org/I1328775524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100658427","display_name":"Chan Wang","orcid":"https://orcid.org/0000-0001-6002-5304","observed_orcids":["https://orcid.org/0000-0001-6002-5304"]},"institutions":[{"id":"https://openalex.org/I1328775524","display_name":"Zhejiang Sci-Tech University","ror":"https://ror.org/03893we55","country_code":"CN","type":"education","lineage":["https://openalex.org/I1328775524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chan Wang","raw_affiliation_strings":["College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","Zhejiang Sci-tech University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","institution_ids":["https://openalex.org/I1328775524"]},{"raw_affiliation_string":"Zhejiang Sci-tech University","institution_ids":["https://openalex.org/I1328775524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072432177","display_name":"Dan Li","orcid":"https://orcid.org/0000-0001-8481-9598","observed_orcids":["https://orcid.org/0000-0001-8481-9598"]},"institutions":[{"id":"https://openalex.org/I1328775524","display_name":"Zhejiang Sci-Tech University","ror":"https://ror.org/03893we55","country_code":"CN","type":"education","lineage":["https://openalex.org/I1328775524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dan Li","raw_affiliation_strings":["College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","Zhejiang Sci-tech University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","institution_ids":["https://openalex.org/I1328775524"]},{"raw_affiliation_string":"Zhejiang Sci-tech University","institution_ids":["https://openalex.org/I1328775524"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yue Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151720","display_name":"ZheJiang Economic and Trade Polytechnic","ror":"https://ror.org/046fb4113","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210151720"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yue Liu","raw_affiliation_strings":["Zhejiang Economic and Trade Polytechnic, Hangzhou, 310018, China","Zhejiang Economic and Trade Polytechnic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zhejiang Economic and Trade Polytechnic, Hangzhou, 310018, China","institution_ids":["https://openalex.org/I4210151720"]},{"raw_affiliation_string":"Zhejiang Economic and Trade Polytechnic","institution_ids":["https://openalex.org/I4210151720"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050766425","display_name":"Qing Sheng","orcid":"https://orcid.org/0000-0002-5435-8177","observed_orcids":["https://orcid.org/0000-0002-5435-8177"]},"institutions":[{"id":"https://openalex.org/I1328775524","display_name":"Zhejiang Sci-Tech University","ror":"https://ror.org/03893we55","country_code":"CN","type":"education","lineage":["https://openalex.org/I1328775524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qing Sheng","raw_affiliation_strings":["College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","Zhejiang Sci-tech University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","institution_ids":["https://openalex.org/I1328775524"]},{"raw_affiliation_string":"Zhejiang Sci-tech University","institution_ids":["https://openalex.org/I1328775524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088299761","display_name":"Zhengbing Lv","orcid":"https://orcid.org/0000-0002-1972-336X","observed_orcids":["https://orcid.org/0000-0002-1972-336X"]},"institutions":[{"id":"https://openalex.org/I1328775524","display_name":"Zhejiang Sci-Tech University","ror":"https://ror.org/03893we55","country_code":"CN","type":"education","lineage":["https://openalex.org/I1328775524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhengbing Lv","raw_affiliation_strings":["College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","Zhejiang Sci-tech University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","institution_ids":["https://openalex.org/I1328775524"]},{"raw_affiliation_string":"Zhejiang Sci-tech University","institution_ids":["https://openalex.org/I1328775524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069770938","display_name":"Wei Yu","orcid":"https://orcid.org/0000-0002-0105-4639","observed_orcids":["https://orcid.org/0000-0002-0105-4639","https://orcid.org/0009-0003-2730-8814"]},"institutions":[{"id":"https://openalex.org/I1328775524","display_name":"Zhejiang Sci-Tech University","ror":"https://ror.org/03893we55","country_code":"CN","type":"education","lineage":["https://openalex.org/I1328775524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Yu","raw_affiliation_strings":["College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","Zhejiang Sci-tech University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","institution_ids":["https://openalex.org/I1328775524"]},{"raw_affiliation_string":"Zhejiang Sci-tech University","institution_ids":["https://openalex.org/I1328775524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100709844","display_name":"Dan Wang","orcid":"https://orcid.org/0000-0001-9079-2360","observed_orcids":["https://orcid.org/0000-0001-9079-2360"]},"institutions":[{"id":"https://openalex.org/I1328775524","display_name":"Zhejiang Sci-Tech University","ror":"https://ror.org/03893we55","country_code":"CN","type":"education","lineage":["https://openalex.org/I1328775524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dan Wang","raw_affiliation_strings":["College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","Zhejiang Sci-tech University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","institution_ids":["https://openalex.org/I1328775524"]},{"raw_affiliation_string":"Zhejiang Sci-tech University","institution_ids":["https://openalex.org/I1328775524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036066093","display_name":"Yaozhou Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1328775524","display_name":"Zhejiang Sci-Tech University","ror":"https://ror.org/03893we55","country_code":"CN","type":"education","lineage":["https://openalex.org/I1328775524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yaozhou Zhang","raw_affiliation_strings":["College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","Zhejiang Sci-tech University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","institution_ids":["https://openalex.org/I1328775524"]},{"raw_affiliation_string":"Zhejiang Sci-tech University","institution_ids":["https://openalex.org/I1328775524"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103198420","display_name":"Zuoming Nie","orcid":"https://orcid.org/0000-0002-0464-2241","observed_orcids":["https://orcid.org/0000-0002-0464-2241"]},"institutions":[{"id":"https://openalex.org/I1328775524","display_name":"Zhejiang Sci-Tech University","ror":"https://ror.org/03893we55","country_code":"CN","type":"education","lineage":["https://openalex.org/I1328775524"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zuoming Nie","raw_affiliation_strings":["College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","Zhejiang Sci-tech University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Sciences, Zhejiang Sci-Tech University, Hanghzou, 310018, China","institution_ids":["https://openalex.org/I1328775524"]},{"raw_affiliation_string":"Zhejiang Sci-tech University","institution_ids":["https://openalex.org/I1328775524"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5103198420"],"corresponding_institution_ids":["https://openalex.org/I1328775524"],"apc_list":{"value":3890,"currency":"USD","value_usd":3890},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.10948592,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"173","issue":"8","first_page":"2065","last_page":"2075"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14048","display_name":"Silkworms and Sericulture Research","score":0.5127000212669373,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14048","display_name":"Silkworms and Sericulture Research","score":0.5127000212669373,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.4203999936580658,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.051100000739097595,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/notch-signaling","display_name":"Notch signaling","score":0.8790000081062317},{"id":"https://openalex.org/keywords/bombyx-mori","display_name":"Bombyx mori","score":0.9390000104904175},{"id":"https://openalex.org/keywords/gene-cloning","display_name":"gene cloning","score":0.5809999704360962},{"id":"https://openalex.org/keywords/recombinant-protein-expression","display_name":"recombinant protein expression","score":0.9020000100135803},{"id":"https://openalex.org/keywords/tissue-specific-expression","display_name":"tissue-specific gene expression","score":0.6729999780654907},{"id":"https://openalex.org/keywords/neurogenesis","display_name":"neurogenesis","score":0.7710000276565552},{"id":"https://openalex.org/keywords/dapt","display_name":"DAPT","score":0.8330000042915344},{"id":"https://openalex.org/keywords/gamma-secretase-inhibitors","display_name":"gamma-secretase inhibitors","score":0.8889999985694885},{"id":"https://openalex.org/keywords/drosophila-homolog","display_name":"Drosophila homolog","score":0.6579999923706055},{"id":"https://openalex.org/keywords/orthologs","display_name":"orthologs","score":0.45100000500679016}],"concepts":[{"id":"https://openalex.org/C2778487026","wikidata":"https://www.wikidata.org/wiki/Q134747","display_name":"Bombyx mori","level":3,"score":0.8368669748306274},{"id":"https://openalex.org/C100068826","wikidata":"https://www.wikidata.org/wiki/Q485675","display_name":"Hemolymph","level":2,"score":0.7766176462173462},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7603546380996704},{"id":"https://openalex.org/C2778332815","wikidata":"https://www.wikidata.org/wiki/Q1314183","display_name":"Bombyx","level":4,"score":0.6778987646102905},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.6752105951309204},{"id":"https://openalex.org/C22145727","wikidata":"https://www.wikidata.org/wiki/Q725889","display_name":"Malpighian tubule system","level":4,"score":0.6450775265693665},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.5339053869247437},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5338082909584045},{"id":"https://openalex.org/C161879069","wikidata":"https://www.wikidata.org/wiki/Q904082","display_name":"Notch signaling pathway","level":3,"score":0.5242559909820557},{"id":"https://openalex.org/C173396325","wikidata":"https://www.wikidata.org/wiki/Q1501275","display_name":"Gene knockdown","level":3,"score":0.466081827878952},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4012278914451599},{"id":"https://openalex.org/C173758957","wikidata":"https://www.wikidata.org/wiki/Q129270","display_name":"Larva","level":2,"score":0.17170622944831848},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16106197237968445},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.11449670791625977},{"id":"https://openalex.org/C150149183","wikidata":"https://www.wikidata.org/wiki/Q1940081","display_name":"Midgut","level":3,"score":0.09679821133613586}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007814","descriptor_name":"Larva","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007814","descriptor_name":"Larva","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D007814","descriptor_name":"Larva","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007814","descriptor_name":"Larva","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011679","descriptor_name":"Pupa","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011679","descriptor_name":"Pupa","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D011679","descriptor_name":"Pupa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012831","descriptor_name":"Bombyx","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012831","descriptor_name":"Bombyx","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D012831","descriptor_name":"Bombyx","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012831","descriptor_name":"Bombyx","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019476","descriptor_name":"Insect Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019476","descriptor_name":"Insect Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019476","descriptor_name":"Insect Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051880","descriptor_name":"Receptors, Notch","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051880","descriptor_name":"Receptors, Notch","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s12010-014-1003-2","doi":"https://doi.org/10.1007/s12010-014-1003-2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12010-014-1003-2","pdf_url":null,"source":{"id":"https://openalex.org/S153285774","display_name":"Applied Biochemistry and Biotechnology","issn_l":"0273-2289","issn":["0273-2289","1559-0291"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied Biochemistry and Biotechnology","raw_type":"journal-article"},{"id":"pmid:24916802","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24916802","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied biochemistry and biotechnology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1675105744","https://openalex.org/W1840848923","https://openalex.org/W1897385899","https://openalex.org/W1942428616","https://openalex.org/W1966828612","https://openalex.org/W1967585941","https://openalex.org/W1974908487","https://openalex.org/W1981754545","https://openalex.org/W1990510025","https://openalex.org/W1994964287","https://openalex.org/W2001404678","https://openalex.org/W2004916479","https://openalex.org/W2014490965","https://openalex.org/W2027971163","https://openalex.org/W2030252491","https://openalex.org/W2051493532","https://openalex.org/W2067219166","https://openalex.org/W2083280774","https://openalex.org/W2085948054","https://openalex.org/W2095479321","https://openalex.org/W2098503611","https://openalex.org/W2120986065","https://openalex.org/W2125548273","https://openalex.org/W2127868723","https://openalex.org/W2130411917","https://openalex.org/W2138301962","https://openalex.org/W2140962377","https://openalex.org/W2147855254","https://openalex.org/W2152046097","https://openalex.org/W2152405557","https://openalex.org/W2153591334","https://openalex.org/W2154861644","https://openalex.org/W2155186791","https://openalex.org/W2156675999","https://openalex.org/W2164325262","https://openalex.org/W2166438767","https://openalex.org/W2184274480","https://openalex.org/W2184956494","https://openalex.org/W2188357884","https://openalex.org/W2227154041","https://openalex.org/W2411587592","https://openalex.org/W4242901535"],"related_works":["https://openalex.org/W2020546135","https://openalex.org/W1573042134","https://openalex.org/W2781549530","https://openalex.org/W2406174348","https://openalex.org/W1968244822","https://openalex.org/W4395954460","https://openalex.org/W2337965154","https://openalex.org/W1970681196","https://openalex.org/W2034121682","https://openalex.org/W3171660224"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}