{"id":"https://openalex.org/W2010313871","doi":"https://doi.org/10.1038/mtna.2014.56","title":"Mcam Silencing With RNA Interference Using Magnetofection has Antitumor Effect in Murine Melanoma","display_name":"Mcam Silencing With RNA Interference Using Magnetofection has Antitumor Effect in Murine Melanoma","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2010313871","doi":"https://doi.org/10.1038/mtna.2014.56","mag":"2010313871","pmid":"https://pubmed.ncbi.nlm.nih.gov/25350580","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4217080"},"language":"en","primary_location":{"id":"doi:10.1038/mtna.2014.56","doi":"https://doi.org/10.1038/mtna.2014.56","is_oa":true,"landing_page_url":"https://doi.org/10.1038/mtna.2014.56","pdf_url":null,"source":{"id":"https://openalex.org/S2764969478","display_name":"Molecular Therapy \u2014 Nucleic Acids","issn_l":"2162-2531","issn":["2162-2531"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Therapy - Nucleic Acids","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1038/mtna.2014.56","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028438290","display_name":"Lara Prosen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210111266","display_name":"Kolektor (Slovenia)","ror":"https://ror.org/01tc1se08","country_code":"SI","type":"company","lineage":["https://openalex.org/I4210111266"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Lara Prosen","raw_affiliation_strings":["Kolektor Group, Nanotesla Institute Ljubljana, Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kolektor Group, Nanotesla Institute Ljubljana, Ljubljana, Slovenia","institution_ids":["https://openalex.org/I4210111266"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041997129","display_name":"Bo\u0161tjan Markelc","orcid":"https://orcid.org/0000-0002-8674-702X","observed_orcids":["https://orcid.org/0000-0002-8674-702X"]},"institutions":[{"id":"https://openalex.org/I3019592416","display_name":"Institute of Oncology Ljubljana","ror":"https://ror.org/00y5zsg21","country_code":"SI","type":"facility","lineage":["https://openalex.org/I3019592416"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Bostjan Markelc","raw_affiliation_strings":["Department of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia","institution_ids":["https://openalex.org/I3019592416"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010273003","display_name":"Tanja Dolin\u0161ek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3019592416","display_name":"Institute of Oncology Ljubljana","ror":"https://ror.org/00y5zsg21","country_code":"SI","type":"facility","lineage":["https://openalex.org/I3019592416"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Tanja Dolinsek","raw_affiliation_strings":["Department of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia","institution_ids":["https://openalex.org/I3019592416"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078631648","display_name":"Branka Mu\u0161i\u010d","orcid":"https://orcid.org/0000-0002-3538-9373","observed_orcids":["https://orcid.org/0000-0002-3538-9373"]},"institutions":[{"id":"https://openalex.org/I4210111266","display_name":"Kolektor (Slovenia)","ror":"https://ror.org/01tc1se08","country_code":"SI","type":"company","lineage":["https://openalex.org/I4210111266"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Branka Music","raw_affiliation_strings":["Kolektor Group, Nanotesla Institute Ljubljana, Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kolektor Group, Nanotesla Institute Ljubljana, Ljubljana, Slovenia","institution_ids":["https://openalex.org/I4210111266"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070257255","display_name":"Maja \u010cema\u017ear","orcid":"https://orcid.org/0000-0002-1418-1928","observed_orcids":["https://orcid.org/0000-0002-1418-1928","https://orcid.org/0009-0009-4633-4472"]},"institutions":[{"id":"https://openalex.org/I118905719","display_name":"University of Primorska","ror":"https://ror.org/05xefg082","country_code":"SI","type":"education","lineage":["https://openalex.org/I118905719"]},{"id":"https://openalex.org/I3019592416","display_name":"Institute of Oncology Ljubljana","ror":"https://ror.org/00y5zsg21","country_code":"SI","type":"facility","lineage":["https://openalex.org/I3019592416"]}],"countries":["SI"],"is_corresponding":true,"raw_author_name":"Maja Cemazar","raw_affiliation_strings":["1] Department of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia [2] Department of Natural and Medical Subjects, University of Primorska, Faculty of Health Sciences, Izola, Slovenia","Department of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia","Department of Natural and Medical Subjects, University of Primorska, Faculty of Health Sciences, Izola, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1] Department of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia [2] Department of Natural and Medical Subjects, University of Primorska, Faculty of Health Sciences, Izola, Slovenia","institution_ids":["https://openalex.org/I118905719","https://openalex.org/I3019592416"]},{"raw_affiliation_string":"Department of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia","institution_ids":["https://openalex.org/I3019592416"]},{"raw_affiliation_string":"Department of Natural and Medical Subjects, University of Primorska, Faculty of Health Sciences, Izola, Slovenia","institution_ids":["https://openalex.org/I118905719"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082272086","display_name":"Gregor Ser\u0161a","orcid":"https://orcid.org/0000-0002-7641-5670","observed_orcids":["https://orcid.org/0000-0002-7641-5670"]},"institutions":[{"id":"https://openalex.org/I3019592416","display_name":"Institute of Oncology Ljubljana","ror":"https://ror.org/00y5zsg21","country_code":"SI","type":"facility","lineage":["https://openalex.org/I3019592416"]}],"countries":["SI"],"is_corresponding":true,"raw_author_name":"Gregor Sersa","raw_affiliation_strings":["Department of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia","institution_ids":["https://openalex.org/I3019592416"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5070257255","https://openalex.org/A5082272086"],"corresponding_institution_ids":["https://openalex.org/I118905719","https://openalex.org/I3019592416"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":{"value":3900,"currency":"USD","value_usd":3900},"fwci":1.1454,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.74718863,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"3","issue":null,"first_page":"e205","last_page":"e205"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11455","display_name":"Microbial Inactivation Methods","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cd146","display_name":"CD146","score":0.7860000133514404},{"id":"https://openalex.org/keywords/melanoma","display_name":"melanoma","score":0.8259999752044678},{"id":"https://openalex.org/keywords/rna-interference","display_name":"RNA interference","score":0.8650000095367432},{"id":"https://openalex.org/keywords/magnetofection","display_name":"magnetofection","score":0.8190000057220459},{"id":"https://openalex.org/keywords/gene-electrotransfer","display_name":"gene electrotransfer","score":0.6869999766349792},{"id":"https://openalex.org/keywords/shrna","display_name":"shRNA","score":0.8410000205039978},{"id":"https://openalex.org/keywords/gene-therapy","display_name":"gene therapy","score":0.6299999952316284},{"id":"https://openalex.org/keywords/antiangiogenic-activity","display_name":"antiangiogenic activity","score":0.8009999990463257},{"id":"https://openalex.org/keywords/tumor-cell-migration","display_name":"tumor cell migration","score":0.7440000176429749},{"id":"https://openalex.org/keywords/tumor-cell-proliferation","display_name":"tumor cell proliferation","score":0.8429999947547913},{"id":"https://openalex.org/keywords/nonviral-gene-delivery","display_name":"non-viral gene delivery","score":0.8560000061988831},{"id":"https://openalex.org/keywords/murine-melanoma","display_name":"murine melanoma","score":0.7649999856948853}],"concepts":[{"id":"https://openalex.org/C119056186","wikidata":"https://www.wikidata.org/wiki/Q1431332","display_name":"Gene silencing","level":3,"score":0.8229882717132568},{"id":"https://openalex.org/C2777658100","wikidata":"https://www.wikidata.org/wiki/Q180614","display_name":"Melanoma","level":2,"score":0.782687783241272},{"id":"https://openalex.org/C166703698","wikidata":"https://www.wikidata.org/wiki/Q201993","display_name":"RNA interference","level":4,"score":0.6793559193611145},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6701724529266357},{"id":"https://openalex.org/C190232843","wikidata":"https://www.wikidata.org/wiki/Q1950808","display_name":"Small hairpin RNA","level":4,"score":0.6498505473136902},{"id":"https://openalex.org/C111599444","wikidata":"https://www.wikidata.org/wiki/Q213901","display_name":"Genetic enhancement","level":3,"score":0.6370440125465393},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.6032616496086121},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.5267017483711243},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.456511527299881},{"id":"https://openalex.org/C135983454","wikidata":"https://www.wikidata.org/wiki/Q2790163","display_name":"Gene delivery","level":4,"score":0.43102818727493286},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40406692028045654},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.34820520877838135},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3469385504722595},{"id":"https://openalex.org/C173396325","wikidata":"https://www.wikidata.org/wiki/Q1501275","display_name":"Gene knockdown","level":3,"score":0.28916582465171814},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.28485509753227234},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06231188774108887}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1038/mtna.2014.56","doi":"https://doi.org/10.1038/mtna.2014.56","is_oa":true,"landing_page_url":"https://doi.org/10.1038/mtna.2014.56","pdf_url":null,"source":{"id":"https://openalex.org/S2764969478","display_name":"Molecular Therapy \u2014 Nucleic Acids","issn_l":"2162-2531","issn":["2162-2531"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Therapy - Nucleic Acids","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4217080","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4217080/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4217080/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Ther Nucleic Acids","raw_type":"Text"},{"id":"pmh:oai:europepmc.org:3193826","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4217080","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:25350580","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25350580","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular therapy. Nucleic acids","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:34319bcd341546e2938745cd477b2e2a","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/34319bcd341546e2938745cd477b2e2a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecular Therapy: Nucleic Acids, Vol 3, Iss C (2014)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/mtna.2014.56","doi":"https://doi.org/10.1038/mtna.2014.56","is_oa":true,"landing_page_url":"https://doi.org/10.1038/mtna.2014.56","pdf_url":null,"source":{"id":"https://openalex.org/S2764969478","display_name":"Molecular Therapy \u2014 Nucleic Acids","issn_l":"2162-2531","issn":["2162-2531"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Therapy - Nucleic Acids","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4124655028","display_name":"Antiangiogena genska terapija raka: tar\u010dno zdravljenje z uporabo elektroporacije in magnetnih nanodelcev kot dostavnih sistemov (Slovene)","funder_award_id":"J3-4211","funder_id":"https://openalex.org/F4320322554","funder_display_name":"Javna Agencija za Raziskovalno Dejavnost RS"},{"id":"https://openalex.org/G7551571093","display_name":"Priprava in validacija terapevtskih plazmidov brez selekcijskega gena za antibioti\u010dno rezistenco za gensko terapijo raka z inducibilnimi in tkivno specifi\u010dnimi promotorji (Slovene)","funder_award_id":"J3-4259","funder_id":"https://openalex.org/F4320322554","funder_display_name":"Javna Agencija za Raziskovalno Dejavnost RS"},{"id":"https://openalex.org/G8841238962","display_name":"Development and evaluation of new approaches to cancer treatment","funder_award_id":"P3-0003","funder_id":"https://openalex.org/F4320322554","funder_display_name":"Javna Agencija za Raziskovalno Dejavnost RS"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320322554","display_name":"Javna Agencija za Raziskovalno Dejavnost RS","ror":"https://ror.org/059bp8k51"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2010313871.pdf","grobid_xml":"https://content.openalex.org/works/W2010313871.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W94505130","https://openalex.org/W958172145","https://openalex.org/W1605974471","https://openalex.org/W1967517433","https://openalex.org/W1967661753","https://openalex.org/W1969120034","https://openalex.org/W1970841610","https://openalex.org/W1971169657","https://openalex.org/W1972913617","https://openalex.org/W1977284436","https://openalex.org/W1983587932","https://openalex.org/W1990952171","https://openalex.org/W1996211231","https://openalex.org/W1998434729","https://openalex.org/W2003936360","https://openalex.org/W2016886514","https://openalex.org/W2019011229","https://openalex.org/W2019080218","https://openalex.org/W2023367330","https://openalex.org/W2028137199","https://openalex.org/W2033743897","https://openalex.org/W2039107161","https://openalex.org/W2041130952","https://openalex.org/W2041233469","https://openalex.org/W2042298446","https://openalex.org/W2043267711","https://openalex.org/W2045978018","https://openalex.org/W2051958360","https://openalex.org/W2052726090","https://openalex.org/W2054889473","https://openalex.org/W2057999099","https://openalex.org/W2060595910","https://openalex.org/W2071369426","https://openalex.org/W2079786558","https://openalex.org/W2091925112","https://openalex.org/W2100617578","https://openalex.org/W2101322033","https://openalex.org/W2105275447","https://openalex.org/W2114080448","https://openalex.org/W2115592921","https://openalex.org/W2120413582","https://openalex.org/W2127111932","https://openalex.org/W2127498080","https://openalex.org/W2130727294","https://openalex.org/W2138045682","https://openalex.org/W2146182949","https://openalex.org/W2153244294","https://openalex.org/W2158077331","https://openalex.org/W2158680377","https://openalex.org/W2159851602","https://openalex.org/W2162147695","https://openalex.org/W2167279371","https://openalex.org/W2329591400","https://openalex.org/W6677031486","https://openalex.org/W6677971923"],"related_works":["https://openalex.org/W1975986367","https://openalex.org/W1982126310","https://openalex.org/W2294447681","https://openalex.org/W3193700816","https://openalex.org/W1986622865","https://openalex.org/W2400249100","https://openalex.org/W2082094135","https://openalex.org/W2541294336","https://openalex.org/W2197454186","https://openalex.org/W1998434729"],"abstract_inverted_index":{"The":[0,67,89],"melanoma":[1,9,75,85,134,149,165],"cell":[2],"adhesion":[3],"molecule":[4],"(MCAM)":[5],"is":[6],"involved":[7],"in":[8,71,82,87,127,142,161,177,178],"development":[10],"and":[11,18,64,76,93,109,131,145,167],"its":[12,110],"progression,":[13],"including":[14],"invasiveness,":[15],"metastatic":[16],"potential":[17,24],"angiogenesis.":[19],"Therefore,":[20],"MCAM":[21,58],"represents":[22],"a":[23,50,153],"target":[25],"for":[26],"gene":[27,39,99,114,156,175,181],"therapy":[28,100,117,182],"of":[29,133,164,187],"melanoma,":[30],"whose":[31],"expression":[32],"could":[33],"be":[34,123],"hindered":[35],"with":[36,41,101,118,169],"posttranscriptional":[37],"specific":[38],"silencing":[40,191],"RNA":[42,56],"interference":[43],"technology.":[44],"In":[45],"this":[46],"study,":[47],"we":[48],"constructed":[49],"plasmid":[51],"DNA":[52],"encoding":[53],"short":[54],"hairpin":[55],"against":[57],"(pMCAM)":[59],"to":[60,113,122,184],"explore":[61],"the":[62,129,162,185],"antitumor":[63,94,146],"antiangiogenic":[65,92,140,188],"effects.":[66],"experiments":[68],"were":[69,96],"performed":[70,106],"vitro":[72],"on":[73,84,148],"murine":[74],"endothelial":[77,143],"cells,":[78,135],"as":[79,81,136,138,152],"well":[80,137],"vivo":[83,179],"tumors":[86,168],"mice.":[88],"antiproliferative,":[90],"antimigratory,":[91],"effects":[95],"examined":[97],"after":[98,190],"pMCAM.":[102],"Gene":[103,116],"delivery":[104,157],"was":[105,159],"by":[107,193],"magnetofection,":[108],"efficacy":[111],"compared":[112],"electrotransfer.":[115],"pMCAM":[119],"has":[120],"proved":[121],"an":[124],"effective":[125,160],"approach":[126],"reducing":[128],"proliferation":[130],"migration":[132],"having":[139],"effect":[141,147,189],"cells":[144,166],"tumors.":[150],"Magnetofection":[151],"developing":[154],"nonviral":[155],"system":[158],"transfection":[163],"pMCAM,":[170],"but":[171],"less":[172],"efficient":[173],"than":[174],"electrotransfer":[176],"tumor":[180],"due":[183],"lack":[186],"Mcam":[192],"magnetofection.":[194]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":5}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}
