{"id":"https://openalex.org/W2010313577","doi":"https://doi.org/10.1016/j.juro.2013.05.061","title":"Hypospadias and Genes Related to Genital Tubercle and Early Urethral Development","display_name":"Hypospadias and Genes Related to Genital Tubercle and Early Urethral Development","publication_year":2013,"publication_date":"2013-05-30","ids":{"openalex":"https://openalex.org/W2010313577","doi":"https://doi.org/10.1016/j.juro.2013.05.061","mag":"2010313577","pmid":"https://pubmed.ncbi.nlm.nih.gov/23727413","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4103581"},"language":"en","primary_location":{"id":"doi:10.1016/j.juro.2013.05.061","doi":"https://doi.org/10.1016/j.juro.2013.05.061","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.juro.2013.05.061","pdf_url":null,"source":{"id":"https://openalex.org/S30525748","display_name":"The Journal of Urology","issn_l":"0022-5347","issn":["0022-5347","1527-3792"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Urology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4103581","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002873786","display_name":"Suzan L. Carmichael","orcid":"https://orcid.org/0000-0001-6310-5924","observed_orcids":["https://orcid.org/0000-0001-6310-5924"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suzan L. Carmichael","raw_affiliation_strings":["Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, Stanford, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, Stanford, California","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101866773","display_name":"Chen Ma","orcid":"https://orcid.org/0000-0003-1484-9948","observed_orcids":["https://orcid.org/0000-0003-1484-9948"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chen Ma","raw_affiliation_strings":["Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, Stanford, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, Stanford, California","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112229794","display_name":"Shweta Choudhry","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shweta Choudhry","raw_affiliation_strings":["Department of Urology, University of California, San Francisco, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, University of California, San Francisco, California","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109872516","display_name":"Edward J. Lammer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Edward J. Lammer","raw_affiliation_strings":["Children's Hospital Oakland Research Institute, Oakland, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Hospital Oakland Research Institute, Oakland, California","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035070420","display_name":"John S. Witte","orcid":"https://orcid.org/0000-0003-0146-1434","observed_orcids":["https://orcid.org/0000-0003-0146-1434"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John S. Witte","raw_affiliation_strings":["Department of Urology, University of California, San Francisco, California","Departments of Epidemiology and Biostatistics, and Institute for Human Genetics, University of California, San Francisco, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, University of California, San Francisco, California","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Departments of Epidemiology and Biostatistics, and Institute for Human Genetics, University of California, San Francisco, California","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033044395","display_name":"Gary M. Shaw","orcid":"https://orcid.org/0000-0001-7438-4914","observed_orcids":["https://orcid.org/0000-0001-7438-4914"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary M. Shaw","raw_affiliation_strings":["Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, Stanford, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, Stanford, California","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":5.2007,"has_fulltext":false,"cited_by_count":65,"citation_normalized_percentile":{"value":0.95759476,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"190","issue":"5","first_page":"1884","last_page":"1892"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11815","display_name":"Urological Disorders and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11815","display_name":"Urological Disorders and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13107","display_name":"Congenital limb and hand anomalies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1309","display_name":"Developmental Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11956","display_name":"Sexual Differentiation and Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypospadias","display_name":"hypospadias","score":1.0},{"id":"https://openalex.org/keywords/urethral-development","display_name":"urethral development","score":0.9869999885559082},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.7149999737739563},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9700000286102295},{"id":"https://openalex.org/keywords/bmp-7","display_name":"BMP-7","score":0.9399999976158142},{"id":"https://openalex.org/keywords/fgf10","display_name":"FGF10","score":0.9380000233650208},{"id":"https://openalex.org/keywords/sonic-hedgehog","display_name":"Sonic hedgehog","score":0.7070000171661377},{"id":"https://openalex.org/keywords/wt1","display_name":"WT1","score":0.9860000014305115},{"id":"https://openalex.org/keywords/hoxa13","display_name":"HOXA13","score":0.6970000267028809},{"id":"https://openalex.org/keywords/hoxd13","display_name":"HOXD13","score":0.8270000219345093},{"id":"https://openalex.org/keywords/sry","display_name":"SRY","score":0.7009999752044678},{"id":"https://openalex.org/keywords/congenital-penile-malformation","display_name":"congenital penile malformation","score":0.5509999990463257},{"id":"https://openalex.org/keywords/disease-severity","display_name":"disease severity","score":0.4449999928474426}],"concepts":[{"id":"https://openalex.org/C2777990738","wikidata":"https://www.wikidata.org/wiki/Q1132108","display_name":"Hypospadias","level":2,"score":0.9510341286659241},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8787696361541748},{"id":"https://openalex.org/C183021626","wikidata":"https://www.wikidata.org/wiki/Q4620674","display_name":"Sex organ","level":2,"score":0.5634542107582092},{"id":"https://openalex.org/C2777085111","wikidata":"https://www.wikidata.org/wiki/Q9386","display_name":"Urethra","level":2,"score":0.41868042945861816},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3124330937862396},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.30650031566619873},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07961317896842957},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06778031587600708}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007021","descriptor_name":"Hypospadias","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010413","descriptor_name":"Penis","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014521","descriptor_name":"Urethra","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.juro.2013.05.061","doi":"https://doi.org/10.1016/j.juro.2013.05.061","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.juro.2013.05.061","pdf_url":null,"source":{"id":"https://openalex.org/S30525748","display_name":"The Journal of Urology","issn_l":"0022-5347","issn":["0022-5347","1527-3792"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Urology","raw_type":"journal-article"},{"id":"pmid:23727413","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23727413","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of urology","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:3072521","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4103581","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4103581","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4103581","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Urol","raw_type":"Text"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt8q87w81c","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/8q87w81c","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Urology, vol 190, iss 5","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:3072521","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4103581","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1369071085","display_name":"Genes, environmental exposures, and hypospadias","funder_award_id":"R01ES017060","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"},{"id":"https://openalex.org/G2632263588","display_name":null,"funder_award_id":"6U01-DD-000489","funder_id":"https://openalex.org/F4320332162","funder_display_name":"Centers for Disease Control and Prevention"},{"id":"https://openalex.org/G443683969","display_name":"CALIFORNIA CENTER OF THE NBDPS - FINDING CAUSES AND PREVENTIVES OF BIRTH DEFECTS","funder_award_id":"U01DD000489","funder_id":"https://openalex.org/F4320332162","funder_display_name":"Centers for Disease Control and Prevention"}],"funders":[{"id":"https://openalex.org/F4320308203","display_name":"California Department of Public Health","ror":"https://ror.org/011cc8156"},{"id":"https://openalex.org/F4320332162","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12"},{"id":"https://openalex.org/F4320337361","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W83779009","https://openalex.org/W132919119","https://openalex.org/W639084255","https://openalex.org/W1966466376","https://openalex.org/W1993194063","https://openalex.org/W2004525595","https://openalex.org/W2012396459","https://openalex.org/W2017484652","https://openalex.org/W2021126443","https://openalex.org/W2022223287","https://openalex.org/W2033124248","https://openalex.org/W2036105953","https://openalex.org/W2047385223","https://openalex.org/W2050509563","https://openalex.org/W2060535511","https://openalex.org/W2071893445","https://openalex.org/W2089648887","https://openalex.org/W2098126593","https://openalex.org/W2104399433","https://openalex.org/W2139954661","https://openalex.org/W2143397763","https://openalex.org/W2143595402","https://openalex.org/W2144899898","https://openalex.org/W2152197184","https://openalex.org/W2157205259","https://openalex.org/W2157461735","https://openalex.org/W2158489424","https://openalex.org/W2159969199","https://openalex.org/W2162530578","https://openalex.org/W2166278496","https://openalex.org/W2167708871","https://openalex.org/W6603321940"],"related_works":["https://openalex.org/W2033124248","https://openalex.org/W7047679786","https://openalex.org/W1967752727","https://openalex.org/W2150299415","https://openalex.org/W2921571188","https://openalex.org/W3032618316","https://openalex.org/W2068561627","https://openalex.org/W2949544185","https://openalex.org/W2012396459","https://openalex.org/W1879607952"],"abstract_inverted_index":{"PURPOSE:":[0],"We":[1,29],"determined":[2],"whether":[3],"variants":[4],"in":[5,24,38,78,121,227],"genes":[6,229],"associated":[7,21,124,144,172,191,207,240],"with":[8,22,125,145,192,208,241],"genital":[9,233],"tubercle":[10,234],"(the":[11],"anlage":[12],"for":[13,91,100,116,141,215],"the":[14,95,158],"penis)":[15],"and":[16,54,70,167,182,235],"early":[17,236],"urethral":[18,237],"development":[19,238],"were":[20,86,123,143,160,170,178,206],"hypospadias":[23,133,242],"humans.":[25],"MATERIALS":[26],"AND":[27],"METHODS:":[28],"examined":[30],"293":[31],"relatively":[32],"common":[33],"tag":[34],"single":[35,88,118,138,173,187,203,224],"nucleotide":[36,89,119,139,174,188,204,225],"polymorphisms":[37,90,120,140,175,205,226],"BMP4,":[39],"BMP7,":[40],"FGF8,":[41],"FGF10,":[42],"FGFR2,":[43],"HOXA13,":[44],"HOXD13,":[45],"HOXA4,":[46],"HOXB6,":[47],"SRY,":[48],"WT1,":[49],"WTAP,":[50],"SHH,":[51],"GLI1,":[52,165],"GLI2":[53,166],"GLI3.":[55],"The":[56,112],"analysis":[57],"included":[58],"624":[59],"cases":[60],"(81":[61],"mild,":[62],"319":[63],"moderate,":[64],"209":[65],"severe,":[66],"15":[67],"undetermined":[68],"severity)":[69,103],"844":[71],"population":[72],"based":[73],"nonmalformed":[74],"male":[75],"controls":[76],"born":[77],"California":[79],"from":[80],"1990":[81],"to":[82,147,162,232],"2003.":[83],"RESULTS:":[84],"There":[85],"28":[87],"which":[92],"any":[93],"of":[94,108,132,135,152,156,197],"comparisons":[96],"(ie":[97],"overall":[98],"or":[99],"a":[101,105,128,193,210],"specific":[102],"had":[104],"p":[106],"value":[107],"less":[109],"than":[110],"0.01.":[111],"homozygous":[113],"variant":[114],"genotypes":[115],"4":[117,155],"BMP7":[122],"at":[126],"least":[127],"twofold":[129,211],"increased":[130,149,195,212],"risk":[131,196],"regardless":[134,151],"severity.":[136,153],"Five":[137],"FGF10":[142],"threefold":[146],"fourfold":[148],"risks,":[150],"For":[154,164,184,200],"them":[157],"results":[159,177],"restricted":[161],"whites.":[163],"GLI3":[168],"there":[169],"12":[171],"but":[176],"inconsistent":[179],"by":[180],"severity":[181],"race/ethnicity.":[183],"SHH":[185],"1":[186],"polymorphism":[189],"was":[190],"2.4-fold":[194],"moderate":[198],"hypospadias.":[199,217],"WT1":[201],"6":[202],"approximately":[209],"risk,":[213],"primarily":[214],"severe":[216],"CONCLUSIONS:":[218],"This":[219],"study":[220],"provides":[221],"evidence":[222],"that":[223,230],"several":[228],"contribute":[231],"are":[239],"risk.":[243]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}