{"id":"https://openalex.org/W2010202695","doi":"https://doi.org/10.1016/j.ydbio.2008.05.032","title":"The engineering of developmental regulation","display_name":"The engineering of developmental regulation","publication_year":2008,"publication_date":"2008-07-01","ids":{"openalex":"https://openalex.org/W2010202695","doi":"https://doi.org/10.1016/j.ydbio.2008.05.032","mag":"2010202695"},"language":"en","primary_location":{"id":"doi:10.1016/j.ydbio.2008.05.032","doi":"https://doi.org/10.1016/j.ydbio.2008.05.032","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ydbio.2008.05.032","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0012160608003631/pdf","source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.sciencedirect.com/science/article/pii/S0012160608003631/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030125759","display_name":"Arthur D. Lander","orcid":"https://orcid.org/0000-0002-4380-5525","observed_orcids":["https://orcid.org/0000-0002-4380-5525"]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Arthur D. Lander","raw_affiliation_strings":["Center for Complex Biological Systems, University of California, Irvine, USA","Department of Developmental and Cell Biology, University of California, Irvine, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Complex Biological Systems, University of California, Irvine, USA","institution_ids":["https://openalex.org/I204250578"]},{"raw_affiliation_string":"Department of Developmental and Cell Biology, University of California, Irvine, USA","institution_ids":["https://openalex.org/I204250578"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5030125759"],"corresponding_institution_ids":["https://openalex.org/I204250578"],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10431628,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"319","issue":"2","first_page":"473","last_page":"473"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nodal-signaling","display_name":"Nodal signaling","score":0.8519999980926514},{"id":"https://openalex.org/keywords/lefty","display_name":"Lefty","score":0.9399999976158142},{"id":"https://openalex.org/keywords/transforming-growth-factor-beta","display_name":"TGF-beta","score":0.8659999966621399},{"id":"https://openalex.org/keywords/mesoderm-formation","display_name":"mesoderm formation","score":0.7400000095367432},{"id":"https://openalex.org/keywords/endoderm-formation","display_name":"endoderm formation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/embryonic-stem-cells","display_name":"embryonic stem cells","score":0.9269999861717224},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.8889999985694885},{"id":"https://openalex.org/keywords/protein-diffusion","display_name":"protein diffusion","score":0.9900000095367432},{"id":"https://openalex.org/keywords/long-distance-signaling","display_name":"long-distance signaling","score":0.6639999747276306},{"id":"https://openalex.org/keywords/developmental-regulation","display_name":"developmental regulation","score":0.5910000205039978}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9403233528137207},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.41495281457901},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.3962620794773102},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.35627520084381104}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1016/j.ydbio.2008.05.032","doi":"https://doi.org/10.1016/j.ydbio.2008.05.032","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ydbio.2008.05.032","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0012160608003631/pdf","source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},{"id":"pmh:qt3b57z5hr","doi":null,"is_oa":true,"landing_page_url":"http://www.escholarship.org/uc/item/3b57z5hr","pdf_url":"https://escholarship.org/content/qt3b57z5hr/qt3b57z5hr.pdf","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Lander, AD. (2008). The engineering of developmental regulation. DEVELOPMENTAL BIOLOGY, 319(2), 473 - 473. doi: 10.1016/j.ydbio.2008.05.032. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/3b57z5hr","raw_type":"article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt3b57z5hr","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/3b57z5hr","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"DEVELOPMENTAL BIOLOGY, vol 319, iss 2","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.ydbio.2008.05.032","doi":"https://doi.org/10.1016/j.ydbio.2008.05.032","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ydbio.2008.05.032","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0012160608003631/pdf","source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2010202695.pdf","grobid_xml":"https://content.openalex.org/works/W2010202695.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2773878580","https://openalex.org/W1513929030","https://openalex.org/W4211028684","https://openalex.org/W1989874642","https://openalex.org/W2095762981","https://openalex.org/W2134290089","https://openalex.org/W4413055748","https://openalex.org/W4253690236","https://openalex.org/W2042384080","https://openalex.org/W2008743321"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-04T10:56:28.161419","created_date":"2016-06-24T00:00:00"}