{"id":"https://openalex.org/W2010143070","doi":"https://doi.org/10.1016/j.ab.2005.05.010","title":"A surface modification strategy on silicon nitride for developing biosensors","display_name":"A surface modification strategy on silicon nitride for developing biosensors","publication_year":2005,"publication_date":"2005-06-10","ids":{"openalex":"https://openalex.org/W2010143070","doi":"https://doi.org/10.1016/j.ab.2005.05.010","mag":"2010143070","pmid":"https://pubmed.ncbi.nlm.nih.gov/15993368"},"language":"en","primary_location":{"id":"doi:10.1016/j.ab.2005.05.010","doi":"https://doi.org/10.1016/j.ab.2005.05.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ab.2005.05.010","pdf_url":null,"source":{"id":"https://openalex.org/S7858788","display_name":"Analytical Biochemistry","issn_l":"0003-2697","issn":["0003-2697","1096-0309"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014362134","display_name":"Jinpian Diao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jinpian Diao","raw_affiliation_strings":["School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009786847","display_name":"Dacheng Ren","orcid":"https://orcid.org/0000-0002-6517-906X","observed_orcids":["https://orcid.org/0000-0002-6517-906X"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dacheng Ren","raw_affiliation_strings":["School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075426222","display_name":"J. R. Engstrom","orcid":"https://orcid.org/0000-0001-8505-8188","observed_orcids":["https://orcid.org/0000-0001-8505-8188"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James R. Engstrom","raw_affiliation_strings":["School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060404458","display_name":"Kelvin H. Lee","orcid":"https://orcid.org/0000-0003-0908-2981","observed_orcids":["https://orcid.org/0000-0003-0908-2981"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kelvin H. Lee","raw_affiliation_strings":["School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA","institution_ids":["https://openalex.org/I205783295"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5060404458"],"corresponding_institution_ids":["https://openalex.org/I205783295"],"apc_list":{"value":3540,"currency":"USD","value_usd":3540},"apc_paid":null,"fwci":1.6313,"has_fulltext":false,"cited_by_count":89,"citation_normalized_percentile":{"value":0.81096176,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"343","issue":"2","first_page":"322","last_page":"328"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10859","display_name":"Polymer Surface Interaction Studies","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/silicon-nitride","display_name":"silicon nitride","score":0.8519999980926514},{"id":"https://openalex.org/keywords/surface-modification","display_name":"surface modification","score":0.9599999785423279},{"id":"https://openalex.org/keywords/biosensors","display_name":"biosensors","score":0.7590000033378601},{"id":"https://openalex.org/keywords/protein-immobilization","display_name":"protein immobilization","score":0.7310000061988831},{"id":"https://openalex.org/keywords/silanization","display_name":"silanization","score":0.6850000023841858},{"id":"https://openalex.org/keywords/3-aminopropyltriethoxysilane","display_name":"3-aminopropyltriethoxysilane","score":0.9620000123977661},{"id":"https://openalex.org/keywords/glutaraldehyde-activation","display_name":"glutaraldehyde activation","score":0.8740000128746033},{"id":"https://openalex.org/keywords/hydrofluoric-acid-surface-treatment","display_name":"hydrofluoric acid surface treatment","score":0.703000009059906},{"id":"https://openalex.org/keywords/chemiluminescence-immunoassay","display_name":"chemiluminescence immunoassay","score":0.8949999809265137},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.75},{"id":"https://openalex.org/keywords/pseudomonas-syringae-pv-tomato-dc3000","display_name":"Pseudomonas syringae pv. tomato DC3000","score":0.9409999847412109},{"id":"https://openalex.org/keywords/human-transferrin","display_name":"human transferrin","score":0.9129999876022339},{"id":"https://openalex.org/keywords/protein-microarrays","display_name":"protein microarrays","score":0.5619999766349792}],"concepts":[{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.746269941329956},{"id":"https://openalex.org/C115537861","wikidata":"https://www.wikidata.org/wiki/Q7645993","display_name":"Surface modification","level":2,"score":0.6195427775382996},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5832886695861816},{"id":"https://openalex.org/C2777431650","wikidata":"https://www.wikidata.org/wiki/Q413828","display_name":"Silicon nitride","level":3,"score":0.5448141694068909},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.43576857447624207},{"id":"https://openalex.org/C194760766","wikidata":"https://www.wikidata.org/wiki/Q410851","display_name":"Nitride","level":3,"score":0.4140038788318634},{"id":"https://openalex.org/C544956773","wikidata":"https://www.wikidata.org/wiki/Q670","display_name":"Silicon","level":2,"score":0.376554399728775},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3445425033569336},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.25279003381729126},{"id":"https://openalex.org/C2779227376","wikidata":"https://www.wikidata.org/wiki/Q6505497","display_name":"Layer (electronics)","level":2,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007118","descriptor_name":"Immunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008163","descriptor_name":"Luminescent Measurements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008280","descriptor_name":"Magnetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013499","descriptor_name":"Surface Properties","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014168","descriptor_name":"Transferrin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017136","descriptor_name":"Ion Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017655","descriptor_name":"Silicon Compounds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D018551","descriptor_name":"Solanum lycopersicum","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D018551","descriptor_name":"Solanum lycopersicum","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D044224","descriptor_name":"Pseudomonas syringae","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D044224","descriptor_name":"Pseudomonas syringae","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.ab.2005.05.010","doi":"https://doi.org/10.1016/j.ab.2005.05.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ab.2005.05.010","pdf_url":null,"source":{"id":"https://openalex.org/S7858788","display_name":"Analytical Biochemistry","issn_l":"0003-2697","issn":["0003-2697","1096-0309"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Biochemistry","raw_type":"journal-article"},{"id":"pmid:15993368","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15993368","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306315","display_name":"Camille and Henry Dreyfus Foundation","ror":"https://ror.org/019p8h045"},{"id":"https://openalex.org/F4320332605","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W48585894","https://openalex.org/W217696421","https://openalex.org/W644687904","https://openalex.org/W1763493835","https://openalex.org/W1976102851","https://openalex.org/W1977656533","https://openalex.org/W1980331301","https://openalex.org/W1981932807","https://openalex.org/W1992694670","https://openalex.org/W2003443692","https://openalex.org/W2012383776","https://openalex.org/W2013002293","https://openalex.org/W2024310259","https://openalex.org/W2028497254","https://openalex.org/W2029320367","https://openalex.org/W2030920997","https://openalex.org/W2034896200","https://openalex.org/W2040813210","https://openalex.org/W2041211295","https://openalex.org/W2047922146","https://openalex.org/W2065733362","https://openalex.org/W2066361920","https://openalex.org/W2067878709","https://openalex.org/W2078986864","https://openalex.org/W2119063553","https://openalex.org/W2134742968","https://openalex.org/W2144634347","https://openalex.org/W2170461759","https://openalex.org/W2314225431","https://openalex.org/W3023900604","https://openalex.org/W3084468041"],"related_works":["https://openalex.org/W2072421864","https://openalex.org/W2010195113","https://openalex.org/W1968994504","https://openalex.org/W2073853786","https://openalex.org/W2121554624","https://openalex.org/W1967253814","https://openalex.org/W4385304396","https://openalex.org/W3010973812","https://openalex.org/W121322259","https://openalex.org/W1972021345"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}