{"id":"https://openalex.org/W2010139788","doi":"https://doi.org/10.1016/0005-2760(81)90018-7","title":"Secretion of lipoproteins, apolipoprotein A-I and apolipoprotein E by isolated and perfused liver of rat with experimental nephrotic syndrome","display_name":"Secretion of lipoproteins, apolipoprotein A-I and apolipoprotein E by isolated and perfused liver of rat with experimental nephrotic syndrome","publication_year":1981,"publication_date":"1981-08-01","ids":{"openalex":"https://openalex.org/W2010139788","doi":"https://doi.org/10.1016/0005-2760(81)90018-7","mag":"2010139788","pmid":"https://pubmed.ncbi.nlm.nih.gov/6793079"},"language":"en","primary_location":{"id":"doi:10.1016/0005-2760(81)90018-7","doi":"https://doi.org/10.1016/0005-2760(81)90018-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0005-2760(81)90018-7","pdf_url":null,"source":{"id":"https://openalex.org/S4210194106","display_name":"Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism","issn_l":"0005-2760","issn":["0005-2760","1879-145X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/11380/742907","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009626049","display_name":"Sebastiano Calandra","orcid":"https://orcid.org/0000-0001-6386-9174","observed_orcids":["https://orcid.org/0000-0001-6386-9174"]},"institutions":[{"id":"https://openalex.org/I122346577","display_name":"University of Modena and Reggio Emilia","ror":"https://ror.org/02d4c4y02","country_code":"IT","type":"education","lineage":["https://openalex.org/I122346577"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S. Calandra","raw_affiliation_strings":["Istituto di Patologia Generale, Universit\u00e0 di Modena, Via Campi 287, 41100 ModemItaly"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto di Patologia Generale, Universit\u00e0 di Modena, Via Campi 287, 41100 ModemItaly","institution_ids":["https://openalex.org/I122346577"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009688263","display_name":"Ermanno Gherardi","orcid":"https://orcid.org/0000-0002-0016-2945","observed_orcids":["https://orcid.org/0000-0002-0016-2945"]},"institutions":[{"id":"https://openalex.org/I122346577","display_name":"University of Modena and Reggio Emilia","ror":"https://ror.org/02d4c4y02","country_code":"IT","type":"education","lineage":["https://openalex.org/I122346577"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"E. Gherardi","raw_affiliation_strings":["Istituto di Patologia Generale, Universit\u00e0 di Modena, Via Campi 287, 41100 ModemItaly"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto di Patologia Generale, Universit\u00e0 di Modena, Via Campi 287, 41100 ModemItaly","institution_ids":["https://openalex.org/I122346577"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029659125","display_name":"MENAHEM FAINARU","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799899409","display_name":"Hadassah Medical Center","ror":"https://ror.org/01cqmqj90","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799899409"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"M. Fainaru","raw_affiliation_strings":["Department of Medicine, Haddassah Medical School, JerusalemIsrael"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Haddassah Medical School, JerusalemIsrael","institution_ids":["https://openalex.org/I2799899409"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006376070","display_name":"AMALIA GUAITANI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19630809","display_name":"Mario Negri Institute for Pharmacological Research","ror":"https://ror.org/05aspc753","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I19630809","https://openalex.org/I4210110338","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Guaitani","raw_affiliation_strings":["Istituto di Ricerche Farmacologiche \u2018Mario Negri\u2019, MilanoItaly"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto di Ricerche Farmacologiche \u2018Mario Negri\u2019, MilanoItaly","institution_ids":["https://openalex.org/I19630809"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039273672","display_name":"I. Barto\u0161ek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19630809","display_name":"Mario Negri Institute for Pharmacological Research","ror":"https://ror.org/05aspc753","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I19630809","https://openalex.org/I4210110338","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"I. Bartosek","raw_affiliation_strings":["Istituto di Ricerche Farmacologiche \u2018Mario Negri\u2019, MilanoItaly"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto di Ricerche Farmacologiche \u2018Mario Negri\u2019, MilanoItaly","institution_ids":["https://openalex.org/I19630809"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.4875,"has_fulltext":false,"cited_by_count":54,"citation_normalized_percentile":{"value":0.79506066,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"665","issue":"2","first_page":"331","last_page":"338"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.9301999807357788,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.9301999807357788,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.04479999840259552,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.014000000432133675,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nephrotic-syndrome","display_name":"nephrotic syndrome","score":0.9980000257492065},{"id":"https://openalex.org/keywords/hepatic-lipoprotein-secretion","display_name":"hepatic lipoprotein secretion","score":0.8159999847412109},{"id":"https://openalex.org/keywords/apolipoprotein-a-i","display_name":"apolipoprotein A-I","score":0.9869999885559082},{"id":"https://openalex.org/keywords/apolipoprotein-e","display_name":"apolipoprotein E","score":1.0},{"id":"https://openalex.org/keywords/hdl2-cholesterol","display_name":"HDL2","score":0.8489999771118164},{"id":"https://openalex.org/keywords/hdl3","display_name":"HDL3","score":0.7710000276565552},{"id":"https://openalex.org/keywords/very-low-density-lipoprotein","display_name":"VLDL","score":0.8289999961853027},{"id":"https://openalex.org/keywords/low-density-lipoprotein","display_name":"low-density lipoprotein","score":0.6830000281333923},{"id":"https://openalex.org/keywords/hyperlipoproteinemia","display_name":"hyperlipoproteinemia","score":0.9350000023841858},{"id":"https://openalex.org/keywords/puromycin-aminonucleoside","display_name":"puromycin aminonucleoside","score":0.9259999990463257},{"id":"https://openalex.org/keywords/isolated-perfused-liver","display_name":"isolated perfused liver","score":0.8180000185966492},{"id":"https://openalex.org/keywords/rat-model","display_name":"rat model","score":0.5379999876022339}],"concepts":[{"id":"https://openalex.org/C62746215","wikidata":"https://www.wikidata.org/wiki/Q14890615","display_name":"Apolipoprotein B","level":3,"score":0.8925057053565979},{"id":"https://openalex.org/C8243546","wikidata":"https://www.wikidata.org/wiki/Q419074","display_name":"Very low-density lipoprotein","level":4,"score":0.8308312296867371},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7911241054534912},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7609397768974304},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.7325102090835571},{"id":"https://openalex.org/C2778930706","wikidata":"https://www.wikidata.org/wiki/Q504790","display_name":"Nephrotic syndrome","level":2,"score":0.5889348387718201},{"id":"https://openalex.org/C56623246","wikidata":"https://www.wikidata.org/wiki/Q14916272","display_name":"Apolipoprotein C2","level":5,"score":0.5555346012115479},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5271329879760742},{"id":"https://openalex.org/C57089818","wikidata":"https://www.wikidata.org/wiki/Q424728","display_name":"Apolipoprotein E","level":3,"score":0.4727899730205536},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.4450906813144684},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.28876417875289917},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.19513115286827087},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001053","descriptor_name":"Apolipoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001057","descriptor_name":"Apolipoproteins E","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008074","descriptor_name":"Lipoproteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008074","descriptor_name":"Lipoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009404","descriptor_name":"Nephrotic Syndrome","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D009404","descriptor_name":"Nephrotic Syndrome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010477","descriptor_name":"Perfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011692","descriptor_name":"Puromycin Aminonucleoside","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016632","descriptor_name":"Apolipoprotein A-I","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/0005-2760(81)90018-7","doi":"https://doi.org/10.1016/0005-2760(81)90018-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0005-2760(81)90018-7","pdf_url":null,"source":{"id":"https://openalex.org/S4210194106","display_name":"Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism","issn_l":"0005-2760","issn":["0005-2760","1879-145X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism","raw_type":"journal-article"},{"id":"pmid:6793079","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6793079","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unimore.it:11380/742907","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11380/742907","pdf_url":null,"source":{"id":"https://openalex.org/S4306400718","display_name":"IRIS UNIMORE (University of Modena and Reggio Emilia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I122346577","host_organization_name":"University of Modena and Reggio Emilia","host_organization_lineage":["https://openalex.org/I122346577"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:iris.unimore.it:11380/742907","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11380/742907","pdf_url":null,"source":{"id":"https://openalex.org/S4306400718","display_name":"IRIS UNIMORE (University of Modena and Reggio Emilia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I122346577","host_organization_name":"University of Modena and Reggio Emilia","host_organization_lineage":["https://openalex.org/I122346577"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W112017919","https://openalex.org/W599788443","https://openalex.org/W626244189","https://openalex.org/W1625660792","https://openalex.org/W1775749144","https://openalex.org/W1980684135","https://openalex.org/W1989151855","https://openalex.org/W1990204145","https://openalex.org/W2035035438","https://openalex.org/W2049029276","https://openalex.org/W2060303624","https://openalex.org/W2079917977","https://openalex.org/W2088290361","https://openalex.org/W2093860111","https://openalex.org/W2100292365","https://openalex.org/W2157621493","https://openalex.org/W2161803016","https://openalex.org/W2168526937","https://openalex.org/W2170521033","https://openalex.org/W2343588855","https://openalex.org/W2344758783","https://openalex.org/W2398870494","https://openalex.org/W2921053158"],"related_works":["https://openalex.org/W2035035438","https://openalex.org/W1990204145","https://openalex.org/W2185452045","https://openalex.org/W2088290361","https://openalex.org/W1980197566","https://openalex.org/W1985324882","https://openalex.org/W2156247303","https://openalex.org/W1980684135","https://openalex.org/W2605506633","https://openalex.org/W1977914419"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}