{"id":"https://openalex.org/W2010009699","doi":"https://doi.org/10.1159/000365296","title":"Characterization of the Arginolytic Microflora Provides Insights into pH Homeostasis in Human Oral Biofilms","display_name":"Characterization of the Arginolytic Microflora Provides Insights into pH Homeostasis in Human Oral Biofilms","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2010009699","doi":"https://doi.org/10.1159/000365296","mag":"2010009699","pmid":"https://pubmed.ncbi.nlm.nih.gov/25634570","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4313619"},"language":"en","primary_location":{"id":"doi:10.1159/000365296","doi":"https://doi.org/10.1159/000365296","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000365296","pdf_url":null,"source":{"id":"https://openalex.org/S23327923","display_name":"Caries Research","issn_l":"0008-6568","issn":["0008-6568","1421-976X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Caries Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4313619","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110520129","display_name":"Xuelian Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xuelian Huang","raw_affiliation_strings":["Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, Fla., USA","Department of Oral Biology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, Fla., USA","institution_ids":["https://openalex.org/I33213144"]},{"raw_affiliation_string":"Department of Oral Biology and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030695004","display_name":"R. Schulte","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Renee M. Schulte","raw_affiliation_strings":["College of Dentistry, University of Florida, Gainesville, FL, USA","College of Dentistry, University of Florida, Gainesville, Fla., USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Dentistry, University of Florida, Gainesville, FL, USA","institution_ids":["https://openalex.org/I33213144"]},{"raw_affiliation_string":"College of Dentistry, University of Florida, Gainesville, Fla., USA","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022248956","display_name":"Robert A. Burne","orcid":"https://orcid.org/0000-0002-4234-0316","observed_orcids":["https://orcid.org/0000-0002-4234-0316"]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert A. Burne","raw_affiliation_strings":["Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL, USA","Department of Oral Biology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL, USA","institution_ids":["https://openalex.org/I33213144"]},{"raw_affiliation_string":"Department of Oral Biology and","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089517528","display_name":"Marcelle Matos Nascimento","orcid":"https://orcid.org/0000-0002-9536-0038","observed_orcids":["https://orcid.org/0000-0002-9536-0038"]},"institutions":[{"id":"https://openalex.org/I2800717037","display_name":"University of Florida Health","ror":"https://ror.org/04tk2gy88","country_code":"US","type":"education","lineage":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Marcelle M. Nascimento","raw_affiliation_strings":["Department of Restorative Dental Science, Division of Operative Dentistry, College of Dentistry, University of Florida, Gainesville, FL, USA","Division of Operative Dentistry, Department of Restorative Dental Science, College of Dentistry, University of Florida, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Restorative Dental Science, Division of Operative Dentistry, College of Dentistry, University of Florida, Gainesville, FL, USA","institution_ids":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"raw_affiliation_string":"Division of Operative Dentistry, Department of Restorative Dental Science, College of Dentistry, University of Florida, and","institution_ids":["https://openalex.org/I33213144"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5089517528"],"corresponding_institution_ids":["https://openalex.org/I2800717037","https://openalex.org/I33213144"],"apc_list":null,"apc_paid":null,"fwci":12.15,"has_fulltext":false,"cited_by_count":75,"citation_normalized_percentile":{"value":0.99241861,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"49","issue":"2","first_page":"165","last_page":"176"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10368","display_name":"Dental Health and Care Utilization","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/arginine-deiminase-system","display_name":"arginine deiminase system","score":0.9869999885559082},{"id":"https://openalex.org/keywords/dental-plaque","display_name":"dental plaque","score":0.9660000205039978},{"id":"https://openalex.org/keywords/plaque-ph","display_name":"plaque pH","score":0.8370000123977661},{"id":"https://openalex.org/keywords/dental-caries","display_name":"dental caries","score":0.9430000185966492},{"id":"https://openalex.org/keywords/streptococcus-sanguinis","display_name":"Streptococcus sanguinis","score":0.9570000171661377},{"id":"https://openalex.org/keywords/arginine-metabolism","display_name":"arginine metabolism","score":0.8840000033378601},{"id":"https://openalex.org/keywords/inter-individual-variability","display_name":"interindividual variability","score":0.5590000152587891},{"id":"https://openalex.org/keywords/oral-microbiota","display_name":"oral microbiota","score":0.4519999921321869}],"concepts":[{"id":"https://openalex.org/C58123911","wikidata":"https://www.wikidata.org/wiki/Q467410","display_name":"Biofilm","level":3,"score":0.9071582555770874},{"id":"https://openalex.org/C2778430296","wikidata":"https://www.wikidata.org/wiki/Q131452","display_name":"Streptococcus mutans","level":3,"score":0.765392541885376},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.6950126886367798},{"id":"https://openalex.org/C2779914569","wikidata":"https://www.wikidata.org/wiki/Q143504","display_name":"Dental plaque","level":2,"score":0.6793245673179626},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6375679969787598},{"id":"https://openalex.org/C2777186326","wikidata":"https://www.wikidata.org/wiki/Q24722788","display_name":"Arginine deiminase","level":4,"score":0.5356431007385254},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49409011006355286},{"id":"https://openalex.org/C2910160754","wikidata":"https://www.wikidata.org/wiki/Q1500347","display_name":"Oral Microbiome","level":3,"score":0.4707042872905731},{"id":"https://openalex.org/C2778276568","wikidata":"https://www.wikidata.org/wiki/Q190161","display_name":"Streptococcus","level":3,"score":0.459576815366745},{"id":"https://openalex.org/C2777867728","wikidata":"https://www.wikidata.org/wiki/Q2033849","display_name":"Streptococcus sanguinis","level":4,"score":0.418316513299942},{"id":"https://openalex.org/C2777468819","wikidata":"https://www.wikidata.org/wiki/Q173670","display_name":"Arginine","level":3,"score":0.406911700963974},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3356814980506897},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18506664037704468},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.09029603004455566},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001120","descriptor_name":"Arginine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001431","descriptor_name":"Bacteriological Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003731","descriptor_name":"Dental Caries","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D003773","descriptor_name":"Dental Plaque","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D004245","descriptor_name":"DMF Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006867","descriptor_name":"Hydrolases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006867","descriptor_name":"Hydrolases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012336","descriptor_name":"RNA, Ribosomal, 16S","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013291","descriptor_name":"Streptococcus","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D013291","descriptor_name":"Streptococcus","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D013291","descriptor_name":"Streptococcus","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D013298","descriptor_name":"Streptococcus sanguis","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D013298","descriptor_name":"Streptococcus sanguis","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D015971","descriptor_name":"Gene Expression Regulation, Enzymologic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D034367","descriptor_name":"Streptococcus intermedius","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D034367","descriptor_name":"Streptococcus intermedius","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D050260","descriptor_name":"Carbohydrate Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054773","descriptor_name":"Streptococcus gordonii","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D054773","descriptor_name":"Streptococcus gordonii","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1159/000365296","doi":"https://doi.org/10.1159/000365296","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000365296","pdf_url":null,"source":{"id":"https://openalex.org/S23327923","display_name":"Caries Research","issn_l":"0008-6568","issn":["0008-6568","1421-976X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Caries Research","raw_type":"journal-article"},{"id":"pmid:25634570","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25634570","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Caries research","raw_type":"Comparative Study"},{"id":"pmh:oai:pubmedcentral.nih.gov:4313619","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4313619","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Caries Res","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4313619","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4313619","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Caries Res","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4590600412","display_name":"Role of the Spx Regulator in Streptococcus mutans","funder_award_id":"R01DE019783","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G7660686165","display_name":"Oral alkali production and caries prevention in children","funder_award_id":"K23DE023579","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G8296435977","display_name":"Molecular Biology of Oral Alkali Production","funder_award_id":"R01DE010362","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G9000858532","display_name":"Comprehensive Training Program in Oral Biology","funder_award_id":"T90DE021990","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G9000875881","display_name":"Comprehensive Training Program in Oral Biology","funder_award_id":"R90DE022530","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"}],"funders":[{"id":"https://openalex.org/F4320308380","display_name":"Yale University","ror":"https://ror.org/03v76x132"},{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W2689643","https://openalex.org/W23707136","https://openalex.org/W168411484","https://openalex.org/W1641045756","https://openalex.org/W1820310789","https://openalex.org/W1898958950","https://openalex.org/W1967039103","https://openalex.org/W1968572313","https://openalex.org/W1968699842","https://openalex.org/W1968834111","https://openalex.org/W1981766973","https://openalex.org/W1989573570","https://openalex.org/W1989917024","https://openalex.org/W1995425214","https://openalex.org/W2009274118","https://openalex.org/W2011776506","https://openalex.org/W2019094601","https://openalex.org/W2020419333","https://openalex.org/W2023938327","https://openalex.org/W2056771157","https://openalex.org/W2061704109","https://openalex.org/W2074347992","https://openalex.org/W2074724241","https://openalex.org/W2082163780","https://openalex.org/W2083467196","https://openalex.org/W2087127317","https://openalex.org/W2095434472","https://openalex.org/W2095566926","https://openalex.org/W2104771379","https://openalex.org/W2108721940","https://openalex.org/W2121748291","https://openalex.org/W2123053539","https://openalex.org/W2133653160","https://openalex.org/W2139465744","https://openalex.org/W2139962100","https://openalex.org/W2141169896","https://openalex.org/W2141254741","https://openalex.org/W2146681091","https://openalex.org/W2150840120","https://openalex.org/W2156053584","https://openalex.org/W2157105947","https://openalex.org/W2158135731","https://openalex.org/W2168614234","https://openalex.org/W2196768981","https://openalex.org/W2296788837","https://openalex.org/W2523457784","https://openalex.org/W2916841405"],"related_works":["https://openalex.org/W2157145420","https://openalex.org/W2123053539","https://openalex.org/W2943632483","https://openalex.org/W3115506841","https://openalex.org/W2639866400","https://openalex.org/W1997058277","https://openalex.org/W2613655746","https://openalex.org/W2793586044","https://openalex.org/W2777482520","https://openalex.org/W1641045756"],"abstract_inverted_index":{"A":[0],"selected":[1],"group":[2],"of":[3,13,30,47,60,105,163,177,195,223],"oral":[4,32,51,217],"bacteria":[5,49],"commonly":[6],"associated":[7,42],"with":[8,43],"dental":[9,38,57,224,240],"health":[10],"is":[11],"capable":[12],"producing":[14],"alkali":[15],"via":[16],"the":[17,28,48,71,121,161,171,174,193,196,207],"arginine":[18,233],"deiminase":[19],"system":[20],"(ADS),":[21],"which":[22,232],"has":[23,40],"a":[24],"profound":[25],"impact":[26],"on":[27],"pH":[29,237],"human":[31],"biofilms.":[33,52],"An":[34],"increased":[35],"risk":[36],"for":[37,73,173,210],"caries":[39,225],"been":[41],"reduced":[44],"ADS":[45,77,94,107,146,197,214],"activity":[46,78,95,108,154,215],"in":[50,75,152,155,187,192,213,216,231],"Arginolytic":[53],"bacterial":[54,83,106],"strains":[55,84,138,183],"from":[56,110],"plaque":[58,76,236],"samples":[59],"caries-free":[61],"and":[62,67,92,160,199,219,238],"caries-active":[63],"adults":[64],"were":[65,85,97,128],"isolated":[66],"characterized":[68],"to":[69,112,142,157,190],"investigate":[70],"basis":[72,172,209],"differences":[74,191,212],"between":[79,200],"individuals.":[80],"Fifty-six":[81],"ADS-positive":[82,137],"identified":[86],"by":[87],"16S":[88],"rRNA":[89],"gene":[90,147],"sequencing,":[91],"their":[93],"levels":[96],"compared":[98],"under":[99,139],"standard":[100],"growth":[101],"conditions.":[102],"The":[103,202],"spectrum":[104,176],"ranged":[109],"45.2":[111],"688.0":[113],"units":[114],"(mg":[115],"protein)(-1).":[116],"Although":[117],"Streptococcus":[118,126],"sanguinis":[119],"was":[120],"most":[122],"prevalent":[123],"species,":[124],"other":[125],"sp.":[127],"also":[129],"represented.":[130],"Biochemical":[131],"assays":[132],"carried":[133],"out":[134],"using":[135],"27":[136],"conditions":[140],"known":[141],"induce":[143],"or":[144,165],"repress":[145],"expression":[148,179],"showed":[149],"substantial":[150],"variation":[151],"arginolytic":[153,178],"response":[156],"pH,":[158],"oxygen":[159],"availability":[162],"carbohydrate":[164],"arginine.":[166],"This":[167],"study":[168],"reveals":[169],"that":[170],"wide":[175],"observed":[180],"among":[181],"clinical":[182],"is,":[184],"at":[185],"least":[186],"part,":[188],"attributable":[189],"regulation":[194],"within":[198],"species.":[201],"results":[203],"provide":[204],"insights":[205],"into":[206],"microbiological":[208],"intersubject":[211],"biofilms":[218],"enhance":[220],"our":[221],"understanding":[222],"as":[226],"an":[227],"ecologically":[228],"driven":[229],"disease":[230],"metabolism":[234],"moderates":[235],"promotes":[239],"health.":[241]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":12},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":4},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}