{"id":"https://openalex.org/W2009798018","doi":"https://doi.org/10.1089/met.2012.0045","title":"The Effect of Sleep Apnea and Insomnia on Blood Levels of Leptin, Insulin Resistance, IP-10, and Hydrogen Sulfide in Type 2 Diabetic Patients","display_name":"The Effect of Sleep Apnea and Insomnia on Blood Levels of Leptin, Insulin Resistance, IP-10, and Hydrogen Sulfide in Type 2 Diabetic Patients","publication_year":2012,"publication_date":"2012-06-29","ids":{"openalex":"https://openalex.org/W2009798018","doi":"https://doi.org/10.1089/met.2012.0045","mag":"2009798018","pmid":"https://pubmed.ncbi.nlm.nih.gov/22746298","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3503462"},"language":"en","primary_location":{"id":"doi:10.1089/met.2012.0045","doi":"https://doi.org/10.1089/met.2012.0045","is_oa":false,"landing_page_url":"https://doi.org/10.1089/met.2012.0045","pdf_url":null,"source":{"id":"https://openalex.org/S61453932","display_name":"Metabolic Syndrome and Related Disorders","issn_l":"1540-4196","issn":["1540-4196","1557-8518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolic Syndrome and Related Disorders","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3503462","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038808562","display_name":"Sushil Kumar Jain","orcid":"https://orcid.org/0000-0002-9574-0436","observed_orcids":["https://orcid.org/0000-0002-9574-0436","https://orcid.org/0009-0009-5772-5786"]},"institutions":[{"id":"https://openalex.org/I81020160","display_name":"Louisiana State University Health Sciences Center Shreveport","ror":"https://ror.org/03151rh82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I81020160"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sushil K. Jain","raw_affiliation_strings":["Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana","institution_ids":["https://openalex.org/I81020160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003609343","display_name":"Gunjan Kahlon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I81020160","display_name":"Louisiana State University Health Sciences Center Shreveport","ror":"https://ror.org/03151rh82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I81020160"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gunjan Kahlon","raw_affiliation_strings":["Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana","institution_ids":["https://openalex.org/I81020160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012005357","display_name":"Lester Morehead","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I81020160","display_name":"Louisiana State University Health Sciences Center Shreveport","ror":"https://ror.org/03151rh82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I81020160"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lester Morehead","raw_affiliation_strings":["Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana","institution_ids":["https://openalex.org/I81020160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085392481","display_name":"Benjamin J. Lieblong","orcid":"https://orcid.org/0000-0001-7225-7049","observed_orcids":["https://orcid.org/0000-0001-7225-7049"]},"institutions":[{"id":"https://openalex.org/I81020160","display_name":"Louisiana State University Health Sciences Center Shreveport","ror":"https://ror.org/03151rh82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I81020160"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin Lieblong","raw_affiliation_strings":["Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana","institution_ids":["https://openalex.org/I81020160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089362368","display_name":"Tommie Stapleton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I81020160","display_name":"Louisiana State University Health Sciences Center Shreveport","ror":"https://ror.org/03151rh82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I81020160"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tommie Stapleton","raw_affiliation_strings":["Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana","institution_ids":["https://openalex.org/I81020160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057676299","display_name":"Robert D. Hoeldtke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I81020160","display_name":"Louisiana State University Health Sciences Center Shreveport","ror":"https://ror.org/03151rh82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I81020160"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Hoeldtke","raw_affiliation_strings":["Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana","institution_ids":["https://openalex.org/I81020160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113634338","display_name":"Pat Farrington Bass","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I81020160","display_name":"Louisiana State University Health Sciences Center Shreveport","ror":"https://ror.org/03151rh82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I81020160"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pat Farrington Bass","raw_affiliation_strings":["Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana","institution_ids":["https://openalex.org/I81020160"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060230239","display_name":"Steven N. Levine","orcid":"https://orcid.org/0000-0002-6499-0491","observed_orcids":["https://orcid.org/0000-0002-6499-0491"]},"institutions":[{"id":"https://openalex.org/I81020160","display_name":"Louisiana State University Health Sciences Center Shreveport","ror":"https://ror.org/03151rh82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I81020160"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven N. Levine","raw_affiliation_strings":["Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics and Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana","institution_ids":["https://openalex.org/I81020160"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I81020160"],"apc_list":null,"apc_paid":null,"fwci":2.0833,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.8541156,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"10","issue":"5","first_page":"331","last_page":"336"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.86080002784729,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.86080002784729,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.07490000128746033,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10316","display_name":"Sleep and related disorders","score":0.047600001096725464,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sleep-apnea","display_name":"sleep apnea","score":0.9909999966621399},{"id":"https://openalex.org/keywords/insomnia","display_name":"insomnia","score":1.0},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9309999942779541},{"id":"https://openalex.org/keywords/leptin","display_name":"leptin","score":0.996999979019165},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.996999979019165},{"id":"https://openalex.org/keywords/cxcl10","display_name":"CXCL10","score":0.9679999947547913},{"id":"https://openalex.org/keywords/hydrogen-sulfide","display_name":"hydrogen sulfide","score":0.8270000219345093},{"id":"https://openalex.org/keywords/vascular-inflammation","display_name":"vascular inflammation","score":0.8659999966621399},{"id":"https://openalex.org/keywords/sleep-disturbance","display_name":"sleep disorders","score":0.746999979019165},{"id":"https://openalex.org/keywords/body-weight","display_name":"body weight","score":0.6240000128746033}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9530162811279297},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.7884745597839355},{"id":"https://openalex.org/C2781210498","wikidata":"https://www.wikidata.org/wiki/Q1869874","display_name":"Insomnia","level":2,"score":0.6660251617431641},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5766632556915283},{"id":"https://openalex.org/C2777935920","wikidata":"https://www.wikidata.org/wiki/Q213600","display_name":"Sleep apnea","level":2,"score":0.5723019242286682},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.5473417043685913},{"id":"https://openalex.org/C2780613262","wikidata":"https://www.wikidata.org/wiki/Q223739","display_name":"Leptin","level":3,"score":0.5317541360855103},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.5259675979614258},{"id":"https://openalex.org/C2780564542","wikidata":"https://www.wikidata.org/wiki/Q170591","display_name":"Hydrogen sulfide","level":3,"score":0.5156965851783752},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.49252209067344666},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.44691476225852966},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.442410409450531},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.422426700592041},{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.41237300634384155},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.21396073698997498},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C518881349","wikidata":"https://www.wikidata.org/wiki/Q682","display_name":"Sulfur","level":2,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006862","descriptor_name":"Hydrogen Sulfide","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D007319","descriptor_name":"Sleep Initiation and Maintenance Disorders","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D007319","descriptor_name":"Sleep Initiation and Maintenance Disorders","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D007319","descriptor_name":"Sleep Initiation and Maintenance Disorders","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007319","descriptor_name":"Sleep Initiation and Maintenance Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D007333","descriptor_name":"Insulin Resistance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012891","descriptor_name":"Sleep Apnea Syndromes","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D012891","descriptor_name":"Sleep Apnea Syndromes","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D012891","descriptor_name":"Sleep Apnea Syndromes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012891","descriptor_name":"Sleep Apnea Syndromes","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020738","descriptor_name":"Leptin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D054357","descriptor_name":"Chemokine CXCL10","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1089/met.2012.0045","doi":"https://doi.org/10.1089/met.2012.0045","is_oa":false,"landing_page_url":"https://doi.org/10.1089/met.2012.0045","pdf_url":null,"source":{"id":"https://openalex.org/S61453932","display_name":"Metabolic Syndrome and Related Disorders","issn_l":"1540-4196","issn":["1540-4196","1557-8518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolic Syndrome and Related Disorders","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2775961","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3503462","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3503462","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3503462","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metab Syndr Relat Disord","raw_type":"Text"},{"id":"pmid:22746298","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22746298","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolic syndrome and related disorders","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2775961","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3503462","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1897137625","display_name":"Ketosis, Vascular Inflammation and Its Therapy in Type 1 Diabetic Patients","funder_award_id":"R01DK072433","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G2809741337","display_name":null,"funder_award_id":"RO1 DK072433","funder_id":"https://openalex.org/F4320306096","funder_display_name":"Office of Dietary Supplements"}],"funders":[{"id":"https://openalex.org/F4320306096","display_name":"Office of Dietary Supplements","ror":"https://ror.org/01wtjyf13"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W1585980331","https://openalex.org/W1965318110","https://openalex.org/W1972016174","https://openalex.org/W1991490009","https://openalex.org/W1991550867","https://openalex.org/W1994853655","https://openalex.org/W1996044268","https://openalex.org/W2002360764","https://openalex.org/W2003721829","https://openalex.org/W2004712996","https://openalex.org/W2010072332","https://openalex.org/W2028120895","https://openalex.org/W2037342207","https://openalex.org/W2038716568","https://openalex.org/W2041736106","https://openalex.org/W2041904172","https://openalex.org/W2045223197","https://openalex.org/W2054064167","https://openalex.org/W2059122010","https://openalex.org/W2061933065","https://openalex.org/W2063207603","https://openalex.org/W2085439266","https://openalex.org/W2097671736","https://openalex.org/W2098180007","https://openalex.org/W2099380716","https://openalex.org/W2100716242","https://openalex.org/W2108838790","https://openalex.org/W2110403934","https://openalex.org/W2110776535","https://openalex.org/W2124334610","https://openalex.org/W2133667581","https://openalex.org/W2137698647","https://openalex.org/W2140372161","https://openalex.org/W2143000515","https://openalex.org/W2147804877","https://openalex.org/W2154502881","https://openalex.org/W2159558963","https://openalex.org/W2164663685","https://openalex.org/W2171783475","https://openalex.org/W2172161196"],"related_works":["https://openalex.org/W2083465083","https://openalex.org/W2015208148","https://openalex.org/W2110290885","https://openalex.org/W2319888784","https://openalex.org/W2358349489","https://openalex.org/W2043886631","https://openalex.org/W2975823580","https://openalex.org/W2084292135","https://openalex.org/W1997188928","https://openalex.org/W3011393259"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Sleep":[1,156],"deficits":[2,35,125,148,157],"associated":[3,227],"with":[4,37,95,123,127,129,146,150,152,173,179,182,193,195,201,216,228,257],"sleep":[5,34,44,56,124,131,147,154,183,197,217,224,235],"apnea":[6,184,225],"and":[7,15,55,86,88,101,115,164,234,242],"insomnia":[8],"increase":[9,158,237],"the":[10,21,70,238,249],"risk":[11,239,251],"of":[12,42,69,112,161,205,240,252],"vascular":[13,212,253],"inflammation":[14,24,213,241],"insulin":[16,102,116,165,243],"resistance.":[17],"This":[18],"study":[19],"examined":[20],"hypothesis":[22],"that":[23,223],"markers":[25],"are":[26],"higher":[27,211],"in":[28,90,104,121,137,144,171,214,231,255],"those":[29,38,151],"diabetic":[30,64,107],"patients":[31,65,122,145,172,194,200,215],"who":[32,175],"experience":[33],"compared":[36,126,149,167,192],"without":[39],"any":[40],"history":[41],"a":[43,80,229],"disorder.":[45],"METHODS:":[46],"Fasting":[47,109],"blood":[48,110],"was":[49,79,92],"obtained":[50,60],"after":[51],"written":[52],"informed":[53],"consent,":[54],"disorder":[57],"histories":[58],"were":[59,118,134],"from":[61],"type":[62,105,258],"2":[63,106,259],"(n=81)":[66],"attending":[67],"clinics":[68],"Louisiana":[71],"State":[72],"University":[73],"Health":[74],"Sciences":[75],"Center.":[76],"RESULTS:":[77],"There":[78,133],"significant":[81],"correlation":[82],"between":[83],"body":[84],"weight":[85],"leptin,":[87,113,162],"leptin":[89],"turn":[91],"significantly":[93,119,186],"correlated":[94],"10-kDa":[96],"interferon-\u03b3-induced":[97],"protein":[98],"(IP-10)":[99],"levels":[100,111,160,169,191,204],"resistance":[103,117,166],"patients.":[108],"IP-10,":[114,163],"elevated":[120],"diabetics":[128],"normal":[130,153,196],"patterns.":[132,155],"no":[135,177],"differences":[136],"glycosylated":[138],"hemoglobin":[139],"(HbA1c)":[140],"or":[141,199],"fasting":[142],"glucose":[143],"circulating":[159,206,232],"to":[168,210,248],"seen":[170],"diabetes":[174],"reported":[176],"difficulty":[178],"sleep.":[180],"Patients":[181],"had":[185],"lower":[187],"hydrogen":[188],"sulfide":[189],"(H(2)S)":[190],"patterns":[198],"insomnia.":[202],"Low":[203],"H(2)S":[207,233],"could":[208],"contribute":[209,247],"apnea.":[218],"CONCLUSIONS:":[219],"These":[220],"results":[221],"suggest":[222],"is":[226],"decrease":[230],"disorders":[236],"resistance,":[244],"which":[245],"can":[246],"increased":[250],"disease":[254],"subjects":[256],"diabetes.":[260]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}