{"id":"https://openalex.org/W2009669201","doi":"https://doi.org/10.3892/etm.2012.472","title":"Resveratrol analogue HS-1793 induces the modulation of tumor-derived T cells","display_name":"Resveratrol analogue HS-1793 induces the modulation of tumor-derived T cells","publication_year":2012,"publication_date":"2012-02-03","ids":{"openalex":"https://openalex.org/W2009669201","doi":"https://doi.org/10.3892/etm.2012.472","mag":"2009669201","pmid":"https://pubmed.ncbi.nlm.nih.gov/22969934","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3438654"},"language":"en","primary_location":{"id":"doi:10.3892/etm.2012.472","doi":"https://doi.org/10.3892/etm.2012.472","is_oa":true,"landing_page_url":"https://doi.org/10.3892/etm.2012.472","pdf_url":"http://www.spandidos-publications.com/10.3892/etm.2012.472/download","source":{"id":"https://openalex.org/S151424340","display_name":"Experimental and Therapeutic Medicine","issn_l":"1792-0981","issn":["1792-0981","1792-1015"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and Therapeutic Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://www.spandidos-publications.com/10.3892/etm.2012.472/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070485039","display_name":"Yoo Jin Choi","orcid":"https://orcid.org/0000-0002-1142-1842","observed_orcids":["https://orcid.org/0000-0002-1142-1842"]},"institutions":[{"id":"https://openalex.org/I4210148139","display_name":"Dongnam Institute of Radiological & Medical Sciences","ror":"https://ror.org/055fmxa32","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210148139"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"YOO JIN CHOI","raw_affiliation_strings":["Research Center, Dong Nam Institute of Radiological and Medical Sciences, Busan 619-953;","Research Center, Dong Nam Institute of Radiological and Medical Sciences, Busan 619-953, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center, Dong Nam Institute of Radiological and Medical Sciences, Busan 619-953;","institution_ids":["https://openalex.org/I4210148139"]},{"raw_affiliation_string":"Research Center, Dong Nam Institute of Radiological and Medical Sciences, Busan 619-953, Republic of Korea","institution_ids":["https://openalex.org/I4210148139"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015472757","display_name":"Kwangmo Yang","orcid":"https://orcid.org/0000-0002-7176-4935","observed_orcids":["https://orcid.org/0000-0002-7176-4935"]},"institutions":[{"id":"https://openalex.org/I4210148139","display_name":"Dongnam Institute of Radiological & Medical Sciences","ror":"https://ror.org/055fmxa32","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210148139"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"KWANG MO YANG","raw_affiliation_strings":["Research Center, Dong Nam Institute of Radiological and Medical Sciences, Busan 619-953, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center, Dong Nam Institute of Radiological and Medical Sciences, Busan 619-953, Republic of Korea","institution_ids":["https://openalex.org/I4210148139"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051656427","display_name":"Sung\u2010Dae Kim","orcid":"https://orcid.org/0000-0001-9891-8888","observed_orcids":["https://orcid.org/0000-0001-9891-8888"]},"institutions":[{"id":"https://openalex.org/I4210148139","display_name":"Dongnam Institute of Radiological & Medical Sciences","ror":"https://ror.org/055fmxa32","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210148139"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"SUNG DAE KIM","raw_affiliation_strings":["Research Center, Dong Nam Institute of Radiological and Medical Sciences, Busan 619-953, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center, Dong Nam Institute of Radiological and Medical Sciences, Busan 619-953, Republic of Korea","institution_ids":["https://openalex.org/I4210148139"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028974899","display_name":"Young Hyun Yoo","orcid":"https://orcid.org/0000-0002-6809-6737","observed_orcids":["https://orcid.org/0000-0002-6809-6737"]},"institutions":[{"id":"https://openalex.org/I51226738","display_name":"Dong-A University","ror":"https://ror.org/03qvtpc38","country_code":"KR","type":"education","lineage":["https://openalex.org/I51226738"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"YOUNG HYUN YOO","raw_affiliation_strings":["Department of Anatomy and Cell Biology, Dong-A University College of Medicine and Mitochondria Hub Regulation Center, Busan 602-714, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy and Cell Biology, Dong-A University College of Medicine and Mitochondria Hub Regulation Center, Busan 602-714, Republic of Korea","institution_ids":["https://openalex.org/I51226738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102810382","display_name":"Sang Wha Lee","orcid":"https://orcid.org/0000-0002-7451-9978","observed_orcids":["https://orcid.org/0000-0002-7451-9978"]},"institutions":[{"id":"https://openalex.org/I51226738","display_name":"Dong-A University","ror":"https://ror.org/03qvtpc38","country_code":"KR","type":"education","lineage":["https://openalex.org/I51226738"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"SANG WHA LEE","raw_affiliation_strings":["Department of Microbiology, Dong-A University College of Medicine and Mitochondria Hub Regulation Center, Busan 602-714, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Dong-A University College of Medicine and Mitochondria Hub Regulation Center, Busan 602-714, Republic of Korea","institution_ids":["https://openalex.org/I51226738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110797422","display_name":"Su Yeong Seo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51226738","display_name":"Dong-A University","ror":"https://ror.org/03qvtpc38","country_code":"KR","type":"education","lineage":["https://openalex.org/I51226738"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"SU YEONG SEO","raw_affiliation_strings":["Department of Microbiology, Dong-A University College of Medicine and Mitochondria Hub Regulation Center, Busan 602-714, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Dong-A University College of Medicine and Mitochondria Hub Regulation Center, Busan 602-714, Republic of Korea","institution_ids":["https://openalex.org/I51226738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010027820","display_name":"Hongsuk Suh","orcid":"https://orcid.org/0000-0001-9832-8378","observed_orcids":["https://orcid.org/0000-0001-9832-8378"]},"institutions":[{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"HONGSUK SUH","raw_affiliation_strings":["Department of Chemistry, and Chemistry Institute for Functional Materials, Pusan National University , Busan 609-735, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, and Chemistry Institute for Functional Materials, Pusan National University , Busan 609-735, Republic of Korea","institution_ids":["https://openalex.org/I4921948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112023805","display_name":"Sung Tae Yee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I199143407","display_name":"Sunchon National University","ror":"https://ror.org/043jqrs76","country_code":"KR","type":"education","lineage":["https://openalex.org/I199143407"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"SUNG TAE YEE","raw_affiliation_strings":["Department of Biology, Sunchon National University, Sunchon, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Sunchon National University, Sunchon, Republic of Korea","institution_ids":["https://openalex.org/I199143407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102880584","display_name":"Min Ho Jeong","orcid":"https://orcid.org/0000-0002-2424-6481","observed_orcids":["https://orcid.org/0000-0002-2424-6481"]},"institutions":[{"id":"https://openalex.org/I51226738","display_name":"Dong-A University","ror":"https://ror.org/03qvtpc38","country_code":"KR","type":"education","lineage":["https://openalex.org/I51226738"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"MIN HO JEONG","raw_affiliation_strings":["Department of Microbiology, Dong-A University College of Medicine and Mitochondria Hub Regulation Center, Busan 602-714, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Dong-A University College of Medicine and Mitochondria Hub Regulation Center, Busan 602-714, Republic of Korea","institution_ids":["https://openalex.org/I51226738"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072314355","display_name":"Wol Soon Jo","orcid":"https://orcid.org/0000-0003-2823-0994","observed_orcids":["https://orcid.org/0000-0003-2823-0994"]},"institutions":[{"id":"https://openalex.org/I4210148139","display_name":"Dongnam Institute of Radiological & Medical Sciences","ror":"https://ror.org/055fmxa32","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210148139"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"WOL SOON JO","raw_affiliation_strings":["Research Center, Dong Nam Institute of Radiological and Medical Sciences, Busan 619-953, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center, Dong Nam Institute of Radiological and Medical Sciences, Busan 619-953, Republic of Korea","institution_ids":["https://openalex.org/I4210148139"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.284,"has_fulltext":true,"cited_by_count":33,"citation_normalized_percentile":{"value":0.87326516,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"3","issue":"4","first_page":"592","last_page":"598"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11051","display_name":"Sirtuins and Resveratrol in Medicine","score":0.8809000253677368,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11051","display_name":"Sirtuins and Resveratrol in Medicine","score":0.8809000253677368,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.0575999990105629,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.0215000007301569,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/resveratrol-analogs","display_name":"resveratrol analogues","score":0.9789999723434448},{"id":"https://openalex.org/keywords/regulatory-t-cells","display_name":"regulatory T cells","score":0.9490000009536743},{"id":"https://openalex.org/keywords/foxp3","display_name":"Foxp3","score":0.9589999914169312},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.734000027179718},{"id":"https://openalex.org/keywords/tumor-immunosuppression","display_name":"tumor immunosuppression","score":0.8029999732971191},{"id":"https://openalex.org/keywords/antitumor-immunity","display_name":"antitumor immunity","score":0.8240000009536743},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":0.847000002861023},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.8119999766349792},{"id":"https://openalex.org/keywords/interleukin-2","display_name":"interleukin-2","score":0.7850000262260437},{"id":"https://openalex.org/keywords/il-4","display_name":"IL-4","score":0.9929999709129333},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.6610000133514404},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.7329999804496765},{"id":"https://openalex.org/keywords/adjuvant-therapy","display_name":"adjuvant therapy","score":0.546999990940094}],"concepts":[{"id":"https://openalex.org/C2779727006","wikidata":"https://www.wikidata.org/wiki/Q426188","display_name":"FOXP3","level":3,"score":0.7909568548202515},{"id":"https://openalex.org/C2776816829","wikidata":"https://www.wikidata.org/wiki/Q407329","display_name":"Resveratrol","level":2,"score":0.7044147253036499},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5963047742843628},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.5841479301452637},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5735638737678528},{"id":"https://openalex.org/C79484868","wikidata":"https://www.wikidata.org/wiki/Q5971673","display_name":"IL-2 receptor","level":4,"score":0.5688571929931641},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5292985439300537},{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.5268030166625977},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5143018960952759},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4739570617675781},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.47064536809921265},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.4277998208999634},{"id":"https://openalex.org/C2780674031","wikidata":"https://www.wikidata.org/wiki/Q2012719","display_name":"Cancer immunotherapy","level":4,"score":0.42178648710250854},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.2950093150138855},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2645915746688843},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3892/etm.2012.472","doi":"https://doi.org/10.3892/etm.2012.472","is_oa":true,"landing_page_url":"https://doi.org/10.3892/etm.2012.472","pdf_url":"http://www.spandidos-publications.com/10.3892/etm.2012.472/download","source":{"id":"https://openalex.org/S151424340","display_name":"Experimental and Therapeutic Medicine","issn_l":"1792-0981","issn":["1792-0981","1792-1015"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and Therapeutic Medicine","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2442386","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3438654","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:22969934","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22969934","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and therapeutic medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3438654","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3438654/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Exp Ther Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3892/etm.2012.472","doi":"https://doi.org/10.3892/etm.2012.472","is_oa":true,"landing_page_url":"https://doi.org/10.3892/etm.2012.472","pdf_url":"http://www.spandidos-publications.com/10.3892/etm.2012.472/download","source":{"id":"https://openalex.org/S151424340","display_name":"Experimental and Therapeutic Medicine","issn_l":"1792-0981","issn":["1792-0981","1792-1015"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and Therapeutic Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322349","display_name":"Ministry of Education, Science and Technology","ror":"https://ror.org/01p262204"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2009669201.pdf","grobid_xml":"https://content.openalex.org/works/W2009669201.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W5924046","https://openalex.org/W113716995","https://openalex.org/W1480438878","https://openalex.org/W1969876191","https://openalex.org/W1977955576","https://openalex.org/W1983918344","https://openalex.org/W1984484036","https://openalex.org/W1991008196","https://openalex.org/W1994190235","https://openalex.org/W1995914986","https://openalex.org/W2001809800","https://openalex.org/W2037299986","https://openalex.org/W2045893773","https://openalex.org/W2057219696","https://openalex.org/W2061590134","https://openalex.org/W2073310925","https://openalex.org/W2073672027","https://openalex.org/W2092187231","https://openalex.org/W2097074641","https://openalex.org/W2098983864","https://openalex.org/W2114185671","https://openalex.org/W2118278569","https://openalex.org/W2123841470","https://openalex.org/W2142729262","https://openalex.org/W2149864243","https://openalex.org/W2151089147","https://openalex.org/W2151246207","https://openalex.org/W2157633667","https://openalex.org/W2159987448","https://openalex.org/W2160117150","https://openalex.org/W2167877348","https://openalex.org/W2169233545","https://openalex.org/W2171467827","https://openalex.org/W2243112011","https://openalex.org/W2560367415","https://openalex.org/W2784110492","https://openalex.org/W6600223256"],"related_works":["https://openalex.org/W2086312320","https://openalex.org/W3011135594","https://openalex.org/W1995914986","https://openalex.org/W3093598627","https://openalex.org/W2480497491","https://openalex.org/W3168510432","https://openalex.org/W2019342358","https://openalex.org/W2118730537","https://openalex.org/W3134290095","https://openalex.org/W1520458145"],"abstract_inverted_index":{"Recent":[0],"advances":[1],"in":[2,54,81,95,108,162,167,202,220,321],"the":[3,6,13,45,55,59,67,82,99,132,135,163,203,225,235,244,252,279,291],"understanding":[4],"of":[5,41,44,70,85,101,134,142,188,205,262,281],"mechanisms":[7],"responsible":[8],"for":[9,79,91],"tumor":[10,36,56],"progression":[11],"suggest":[12,196,275],"possibility":[14],"to":[15,110,122,297],"control":[16],"cancer":[17,23,323],"growth,":[18],"not":[19],"only":[20],"through":[21],"chemotherapy-induced":[22],"cell":[24,165,211,228,247,257,293],"destruction,":[25],"but":[26],"also":[27],"by":[28,151,159,270],"stimulating":[29],"anticancer":[30],"immunity.":[31,310],"However,":[32],"immune":[33,149],"tolerance":[34],"against":[35],"antigens":[37],"disturbs":[38],"diverse":[39],"forms":[40],"immunotherapy.":[42,324],"One":[43],"most":[46],"potent":[47],"and":[48,76,138,184,259,304],"well-studied":[49],"tumor-induced":[50],"immunosuppressive":[51],"phenotypes":[52],"found":[53],"microenvironment":[57],"is":[58,88],"regulatory":[60],"subpopulation":[61],"cells":[62,233,307],"(CD4(+)CD25(+)FoxP3(+)":[63],"Treg":[64,115,164,292],"cells).":[65],"Among":[66],"great":[68],"number":[69],"natural":[71],"agents":[72],"derived":[73],"from":[74,131,192,213,264],"plants":[75],"potentially":[77],"useful":[78],"application":[80],"complementary":[83],"therapy":[84],"cancer,":[86,97],"resveratrol":[87,128],"gaining":[89],"attention":[90],"its":[92],"immunomodulating":[93],"properties":[94],"breast":[96,169,322],"since":[98],"ineffectiveness":[100],"numerous":[102],"immunotherapy":[103],"strategies":[104],"may":[105,199,313],"be":[106],"related,":[107],"part,":[109],"their":[111],"negative":[112],"effects":[113],"on":[114,148,290],"cells.":[116],"The":[117,209],"present":[118],"study":[119],"was":[120],"undertaken":[121],"examine":[123],"whether":[124],"HS-1793,":[125],"a":[126,145,221,239,287,316],"synthetic":[127],"analogue":[129],"free":[130],"restriction":[133],"metabolic":[136],"instability":[137],"high":[139],"dose":[140],"requirement":[141],"resveratrol,":[143],"shows":[144],"direct":[146,176],"effect":[147,158,289],"responses":[150,303],"enhancing":[152],"lymphocyte":[153,302],"proliferation":[154],"or":[155],"an":[156],"immunomodulatory":[157],"inducing":[160],"changes":[161,201],"population":[166,212,229,237,248,258],"FM3A":[168],"tumor-bearing":[170,193,214,265],"mice.":[171],"Although":[172],"HS-1793":[173,198,218,271,277,312],"had":[174],"no":[175],"immunostimulatory":[177],"effect,":[178],"it":[179],"dose-dependently":[180],"decreased":[181,216],"IL-2":[182],"secretion":[183,187,261],"increased":[185],"IL-4":[186],"concanavalin":[189],"A-stimulated":[190],"lymphocytes":[191],"mice,":[194],"which":[195],"that":[197,276],"induce":[200],"subpopulations":[204],"tumor-derived":[206,282],"T":[207,227,246,256,283,301,306],"lymphocytes.":[208],"CD4(+)CD25(+)":[210,236],"mice":[215,266],"after":[217],"treatment":[219],"dose-dependent":[222],"manner,":[223],"while":[224],"CD4(+)":[226,305],"remained":[230],"unchanged.":[231],"FoxP3(+)-expressing":[232],"among":[234],"showed":[238],"similar":[240],"pattern.":[241],"In":[242],"contrast,":[243],"CD8(+)":[245,255],"as":[249,251,315],"well":[250],"interferon":[253],"(IFN)-\u03b3-expressing":[254],"IFN-\u03b3":[260],"splenocytes":[263],"were":[267],"significantly":[268],"upregulated":[269],"treatment.":[272],"These":[273],"results":[274],"induces":[278],"modulation":[280],"lymphocytes,":[284],"particulary":[285],"having":[286],"suppressive":[288],"population,":[294],"likely":[295],"contributing":[296],"enhanced":[298],"tumor-specific":[299],"cytotoxic":[300],"involving":[308],"antitumor":[309],"Therefore,":[311],"serve":[314],"promising":[317],"adjuvant":[318],"therapeutic":[319],"reagent":[320]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}