{"id":"https://openalex.org/W2009592543","doi":"https://doi.org/10.1016/j.niox.2014.11.001","title":"H2S-induced HCO3\u2212 secretion in the rat stomach \u2013 Involvement of nitric oxide, prostaglandins, and capsaicin-sensitive sensory neurons","display_name":"H2S-induced HCO3\u2212 secretion in the rat stomach \u2013 Involvement of nitric oxide, prostaglandins, and capsaicin-sensitive sensory neurons","publication_year":2014,"publication_date":"2014-11-07","ids":{"openalex":"https://openalex.org/W2009592543","doi":"https://doi.org/10.1016/j.niox.2014.11.001","mag":"2009592543","pmid":"https://pubmed.ncbi.nlm.nih.gov/25460323"},"language":"en","primary_location":{"id":"doi:10.1016/j.niox.2014.11.001","doi":"https://doi.org/10.1016/j.niox.2014.11.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.niox.2014.11.001","pdf_url":null,"source":{"id":"https://openalex.org/S152998702","display_name":"Nitric Oxide","issn_l":"1089-8603","issn":["1089-8603","1089-8611"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nitric Oxide","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090713682","display_name":"Koji Takeuchi","orcid":"https://orcid.org/0000-0002-9668-6021","observed_orcids":["https://orcid.org/0000-0002-9668-6021","https://orcid.org/0009-0008-3293-2730"]},"institutions":[{"id":"https://openalex.org/I25998863","display_name":"Kyoto Pharmaceutical University","ror":"https://ror.org/01ytgve10","country_code":"JP","type":"education","lineage":["https://openalex.org/I25998863"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Koji Takeuchi","raw_affiliation_strings":["Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto 607-8414, Japan; General Incorporated Association, Kyoto Research Center for Gastrointestinal Diseases, Karasuma-Oike, 671, Kyoto 604-8106, Japan. Electronic address: takeuchi@mb.kyoto-phu.ac.jp","Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto 607-8414, Japan","General Incorporated Association, Kyoto Research Center for Gastrointestinal Diseases, Karasuma-Oike, 671, Kyoto 604-8106, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto 607-8414, Japan; General Incorporated Association, Kyoto Research Center for Gastrointestinal Diseases, Karasuma-Oike, 671, Kyoto 604-8106, Japan. Electronic address: takeuchi@mb.kyoto-phu.ac.jp","institution_ids":["https://openalex.org/I25998863"]},{"raw_affiliation_string":"Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto 607-8414, Japan","institution_ids":["https://openalex.org/I25998863"]},{"raw_affiliation_string":"General Incorporated Association, Kyoto Research Center for Gastrointestinal Diseases, Karasuma-Oike, 671, Kyoto 604-8106, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026529624","display_name":"Fumitaka Ise","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25998863","display_name":"Kyoto Pharmaceutical University","ror":"https://ror.org/01ytgve10","country_code":"JP","type":"education","lineage":["https://openalex.org/I25998863"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Fumitaka Ise","raw_affiliation_strings":["Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto 607-8414, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto 607-8414, Japan","institution_ids":["https://openalex.org/I25998863"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109206625","display_name":"Kento Takahashi","orcid":"https://orcid.org/0009-0007-7447-7708","observed_orcids":["https://orcid.org/0009-0007-7447-7708"]},"institutions":[{"id":"https://openalex.org/I25998863","display_name":"Kyoto Pharmaceutical University","ror":"https://ror.org/01ytgve10","country_code":"JP","type":"education","lineage":["https://openalex.org/I25998863"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kento Takahashi","raw_affiliation_strings":["Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto 607-8414, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto 607-8414, Japan","institution_ids":["https://openalex.org/I25998863"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086552382","display_name":"Eitaro Aihara","orcid":"https://orcid.org/0000-0003-1160-4929","observed_orcids":["https://orcid.org/0000-0003-1160-4929"]},"institutions":[{"id":"https://openalex.org/I25998863","display_name":"Kyoto Pharmaceutical University","ror":"https://ror.org/01ytgve10","country_code":"JP","type":"education","lineage":["https://openalex.org/I25998863"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Eitaro Aihara","raw_affiliation_strings":["Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto 607-8414, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto 607-8414, Japan","institution_ids":["https://openalex.org/I25998863"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049280193","display_name":"Shusaku Hayashi","orcid":"https://orcid.org/0000-0002-8304-7255","observed_orcids":["https://orcid.org/0000-0002-8304-7255"]},"institutions":[{"id":"https://openalex.org/I25998863","display_name":"Kyoto Pharmaceutical University","ror":"https://ror.org/01ytgve10","country_code":"JP","type":"education","lineage":["https://openalex.org/I25998863"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shusaku Hayashi","raw_affiliation_strings":["Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto 607-8414, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto 607-8414, Japan","institution_ids":["https://openalex.org/I25998863"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5090713682"],"corresponding_institution_ids":["https://openalex.org/I25998863"],"apc_list":{"value":3400,"currency":"USD","value_usd":3400},"apc_paid":null,"fwci":1.6288,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.78974714,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"46","issue":null,"first_page":"157","last_page":"164"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11481","display_name":"Sulfur Compounds in Biology","score":0.8812999725341797,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11481","display_name":"Sulfur Compounds in Biology","score":0.8812999725341797,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.09030000120401382,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.006800000090152025,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hydrogen-sulfide","display_name":"hydrogen sulfide","score":1.0},{"id":"https://openalex.org/keywords/bicarbonate-secretion","display_name":"bicarbonate secretion","score":0.8289999961853027},{"id":"https://openalex.org/keywords/gastric-secretion","display_name":"gastric secretion","score":0.6759999990463257},{"id":"https://openalex.org/keywords/prostaglandins","display_name":"prostaglandins","score":0.875},{"id":"https://openalex.org/keywords/prostaglandin-e2","display_name":"prostaglandin E2","score":0.8939999938011169},{"id":"https://openalex.org/keywords/capsaicin-sensitive-sensory-neurons","display_name":"capsaicin-sensitive sensory neurons","score":0.9449999928474426},{"id":"https://openalex.org/keywords/cystathionine-gamma-lyase","display_name":"cystathionine gamma-lyase","score":0.925000011920929},{"id":"https://openalex.org/keywords/atp-sensitive-potassium-channels","display_name":"ATP-sensitive potassium channels","score":0.8220000267028809},{"id":"https://openalex.org/keywords/sensory-deafferentation","display_name":"sensory deafferentation","score":0.8790000081062317},{"id":"https://openalex.org/keywords/indomethacin","display_name":"indomethacin","score":0.7310000061988831},{"id":"https://openalex.org/keywords/l-name","display_name":"L-NAME","score":0.9110000133514404},{"id":"https://openalex.org/keywords/glibenclamide","display_name":"glibenclamide","score":0.7900000214576721},{"id":"https://openalex.org/keywords/propargylglycine","display_name":"propargylglycine","score":0.890999972820282},{"id":"https://openalex.org/keywords/sodium-hydrosulfide","display_name":"sodium hydrosulfide","score":0.5979999899864197}],"concepts":[{"id":"https://openalex.org/C2779768347","wikidata":"https://www.wikidata.org/wiki/Q420626","display_name":"Glibenclamide","level":3,"score":0.7966128587722778},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.7806822061538696},{"id":"https://openalex.org/C2780051329","wikidata":"https://www.wikidata.org/wiki/Q273169","display_name":"Capsaicin","level":3,"score":0.7137802839279175},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7047218680381775},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.5394275188446045},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5096266269683838},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.47511276602745056},{"id":"https://openalex.org/C2780664492","wikidata":"https://www.wikidata.org/wiki/Q209717","display_name":"Prostaglandin","level":2,"score":0.443494975566864},{"id":"https://openalex.org/C2777622882","wikidata":"https://www.wikidata.org/wiki/Q417619","display_name":"Nitric oxide synthase","level":3,"score":0.4216364622116089},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3466249108314514},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21002912521362305},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18594935536384583},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.15121117234230042},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001639","descriptor_name":"Bicarbonates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002211","descriptor_name":"Capsaicin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D005753","descriptor_name":"Gastric Mucosa","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005753","descriptor_name":"Gastric Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006862","descriptor_name":"Hydrogen Sulfide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007213","descriptor_name":"Indomethacin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011453","descriptor_name":"Prostaglandins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011984","descriptor_name":"Sensory Receptor Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011984","descriptor_name":"Sensory Receptor Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013270","descriptor_name":"Stomach","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013270","descriptor_name":"Stomach","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D013270","descriptor_name":"Stomach","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013440","descriptor_name":"Sulfides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019331","descriptor_name":"NG-Nitroarginine Methyl Ester","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.niox.2014.11.001","doi":"https://doi.org/10.1016/j.niox.2014.11.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.niox.2014.11.001","pdf_url":null,"source":{"id":"https://openalex.org/S152998702","display_name":"Nitric Oxide","issn_l":"1089-8603","issn":["1089-8603","1089-8611"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nitric Oxide","raw_type":"journal-article"},{"id":"pmid:25460323","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25460323","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nitric oxide : biology and chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.428600013256073}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5366388715","display_name":"Role of CD206 Positive Macrophages in the Intestinal Homeostasis and Inflammatory Bowel Disease","funder_award_id":"15K18873","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W106800896","https://openalex.org/W333477813","https://openalex.org/W1174652935","https://openalex.org/W1607540395","https://openalex.org/W1628129021","https://openalex.org/W1652980032","https://openalex.org/W1714723617","https://openalex.org/W1913770988","https://openalex.org/W1942962978","https://openalex.org/W1975072795","https://openalex.org/W1976599798","https://openalex.org/W1984355177","https://openalex.org/W1985344167","https://openalex.org/W1990802251","https://openalex.org/W1991824136","https://openalex.org/W1992190262","https://openalex.org/W1995340021","https://openalex.org/W1995636631","https://openalex.org/W2000707489","https://openalex.org/W2002371664","https://openalex.org/W2011350442","https://openalex.org/W2011773715","https://openalex.org/W2015407072","https://openalex.org/W2032861502","https://openalex.org/W2034679499","https://openalex.org/W2039787701","https://openalex.org/W2048036642","https://openalex.org/W2049844609","https://openalex.org/W2054510030","https://openalex.org/W2056635601","https://openalex.org/W2081477898","https://openalex.org/W2085339787","https://openalex.org/W2089598730","https://openalex.org/W2090064508","https://openalex.org/W2098595683","https://openalex.org/W2119363396","https://openalex.org/W2141610173","https://openalex.org/W2143099904","https://openalex.org/W2168990431","https://openalex.org/W2292069179","https://openalex.org/W2301592343","https://openalex.org/W2419023971","https://openalex.org/W6627902188","https://openalex.org/W6646298640","https://openalex.org/W6717128991"],"related_works":["https://openalex.org/W1942962978","https://openalex.org/W2027377685","https://openalex.org/W1722258113","https://openalex.org/W1970945123","https://openalex.org/W1974516371","https://openalex.org/W2064334281","https://openalex.org/W2143099904","https://openalex.org/W2271171384","https://openalex.org/W2310287454","https://openalex.org/W2068671535"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}