{"id":"https://openalex.org/W2009351663","doi":"https://doi.org/10.1016/j.mrfmmm.2007.07.014","title":"Carbamazepine induces mitotic arrest in mammalian Vero cells","display_name":"Carbamazepine induces mitotic arrest in mammalian Vero cells","publication_year":2007,"publication_date":"2007-08-07","ids":{"openalex":"https://openalex.org/W2009351663","doi":"https://doi.org/10.1016/j.mrfmmm.2007.07.014","mag":"2009351663","pmid":"https://pubmed.ncbi.nlm.nih.gov/17875314"},"language":"en","primary_location":{"id":"doi:10.1016/j.mrfmmm.2007.07.014","doi":"https://doi.org/10.1016/j.mrfmmm.2007.07.014","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.mrfmmm.2007.07.014","pdf_url":null,"source":{"id":"https://openalex.org/S4394735698","display_name":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","issn_l":"0027-5107","issn":["0027-5107","1386-1964","1873-135X","1879-2871"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102945053","display_name":"Jos\u00e9 Manuel P\u00e9rez Mart\u00edn","orcid":"https://orcid.org/0000-0002-0658-9050","observed_orcids":["https://orcid.org/0000-0002-0658-9050"]},"institutions":[{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"J.M. P\u00e9rez Mart\u00edn","raw_affiliation_strings":["Departamento de Biolog\u00eda, Facultad de Ciencias, Universidad Aut\u00f3noma de Madrid, Cantoblanco, 28049, Madrid, Spain","Departamento de Biologi\u0301a, Facultad de Ciencias, Universidad Auto\u0301noma de Madrid, Cantoblanco, 28049 Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Biolog\u00eda, Facultad de Ciencias, Universidad Aut\u00f3noma de Madrid, Cantoblanco, 28049, Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]},{"raw_affiliation_string":"Departamento de Biologi\u0301a, Facultad de Ciencias, Universidad Auto\u0301noma de Madrid, Cantoblanco, 28049 Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082424667","display_name":"Paloma Fern\u00e1ndez Freire","orcid":"https://orcid.org/0000-0003-1357-8955","observed_orcids":["https://orcid.org/0000-0003-1357-8955"]},"institutions":[{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"P. Fern\u00e1ndez Freire","raw_affiliation_strings":["Departamento de Biolog\u00eda, Facultad de Ciencias, Universidad Aut\u00f3noma de Madrid, Cantoblanco, 28049 Madrid, Spain","Departamento de Biologi\u0301a, Facultad de Ciencias, Universidad Auto\u0301noma de Madrid, Cantoblanco, 28049 Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Biolog\u00eda, Facultad de Ciencias, Universidad Aut\u00f3noma de Madrid, Cantoblanco, 28049 Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]},{"raw_affiliation_string":"Departamento de Biologi\u0301a, Facultad de Ciencias, Universidad Auto\u0301noma de Madrid, Cantoblanco, 28049 Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008214087","display_name":"Ver\u00f3nica Labrador-Cantarero","orcid":"https://orcid.org/0000-0001-9907-4998","observed_orcids":["https://orcid.org/0000-0001-9907-4998"]},"institutions":[{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"V. Labrador","raw_affiliation_strings":["Departamento de Biolog\u00eda, Facultad de Ciencias, Universidad Aut\u00f3noma de Madrid, Cantoblanco, 28049 Madrid, Spain","Departamento de Biologi\u0301a, Facultad de Ciencias, Universidad Auto\u0301noma de Madrid, Cantoblanco, 28049 Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Biolog\u00eda, Facultad de Ciencias, Universidad Aut\u00f3noma de Madrid, Cantoblanco, 28049 Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]},{"raw_affiliation_string":"Departamento de Biologi\u0301a, Facultad de Ciencias, Universidad Auto\u0301noma de Madrid, Cantoblanco, 28049 Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111785184","display_name":"Maria Jos\u00e9 Hazen","orcid":"https://orcid.org/0000-0002-6729-5347","observed_orcids":["https://orcid.org/0000-0002-6729-5347"]},"institutions":[{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"M.J. Hazen","raw_affiliation_strings":["Departamento de Biolog\u00eda, Facultad de Ciencias, Universidad Aut\u00f3noma de Madrid, Cantoblanco, 28049 Madrid, Spain","Departamento de Biologi\u0301a, Facultad de Ciencias, Universidad Auto\u0301noma de Madrid, Cantoblanco, 28049 Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Biolog\u00eda, Facultad de Ciencias, Universidad Aut\u00f3noma de Madrid, Cantoblanco, 28049 Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]},{"raw_affiliation_string":"Departamento de Biologi\u0301a, Facultad de Ciencias, Universidad Auto\u0301noma de Madrid, Cantoblanco, 28049 Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111785184"],"corresponding_institution_ids":["https://openalex.org/I63634437"],"apc_list":{"value":3380,"currency":"USD","value_usd":3380},"apc_paid":null,"fwci":0.469,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.57003538,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"637","issue":"1-2","first_page":"124","last_page":"133"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carbamazepine","display_name":"carbamazepine","score":1.0},{"id":"https://openalex.org/keywords/mitotic-arrest","display_name":"mitotic arrest","score":0.984000027179718},{"id":"https://openalex.org/keywords/vero-cells","display_name":"Vero cells","score":0.7940000295639038},{"id":"https://openalex.org/keywords/antiproliferative-activity","display_name":"antiproliferative activity","score":0.7400000095367432},{"id":"https://openalex.org/keywords/monopolar-spindle","display_name":"monopolar spindle","score":0.8270000219345093},{"id":"https://openalex.org/keywords/centrosome-separation","display_name":"centrosome separation","score":0.9829999804496765},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.6759999990463257},{"id":"https://openalex.org/keywords/antiepileptic-drugs","display_name":"antiepileptic drugs","score":0.847000002861023},{"id":"https://openalex.org/keywords/cytostatic-effect","display_name":"cytostatic activity","score":0.8159999847412109},{"id":"https://openalex.org/keywords/drug-induced-cell-death","display_name":"drug-induced cell death","score":0.49799999594688416}],"concepts":[{"id":"https://openalex.org/C93304396","wikidata":"https://www.wikidata.org/wiki/Q14763008","display_name":"Mitosis","level":2,"score":0.7979485988616943},{"id":"https://openalex.org/C70278784","wikidata":"https://www.wikidata.org/wiki/Q574427","display_name":"Metaphase","level":4,"score":0.7518090009689331},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6719149351119995},{"id":"https://openalex.org/C66640590","wikidata":"https://www.wikidata.org/wiki/Q4296711","display_name":"Mitotic index","level":3,"score":0.530888020992279},{"id":"https://openalex.org/C47432576","wikidata":"https://www.wikidata.org/wiki/Q918594","display_name":"Spindle apparatus","level":4,"score":0.5070929527282715},{"id":"https://openalex.org/C2779253243","wikidata":"https://www.wikidata.org/wiki/Q410412","display_name":"Carbamazepine","level":3,"score":0.46074190735816956},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.4594804048538208},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.43524619936943054},{"id":"https://openalex.org/C89138240","wikidata":"https://www.wikidata.org/wiki/Q3066564","display_name":"Vero cell","level":3,"score":0.4306986629962921},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4073946475982666},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.33944153785705566},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3217458724975586},{"id":"https://openalex.org/C85813293","wikidata":"https://www.wikidata.org/wiki/Q188909","display_name":"Cell division","level":3,"score":0.25096064805984497},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.24418765306472778},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15527614951133728},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.14556065201759338},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12320894002914429},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002220","descriptor_name":"Carbamazepine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002453","descriptor_name":"Cell Cycle","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002522","descriptor_name":"Chlorocebus aethiops","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008938","descriptor_name":"Mitosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008941","descriptor_name":"Spindle Apparatus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.mrfmmm.2007.07.014","doi":"https://doi.org/10.1016/j.mrfmmm.2007.07.014","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.mrfmmm.2007.07.014","pdf_url":null,"source":{"id":"https://openalex.org/S4394735698","display_name":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","issn_l":"0027-5107","issn":["0027-5107","1386-1964","1873-135X","1879-2871"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis","raw_type":"journal-article"},{"id":"pmid:17875314","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17875314","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321764","display_name":"Ministerio de Educaci\u00f3n, Cultura y Deporte","ror":"https://ror.org/03nc27g21"},{"id":"https://openalex.org/F4320322755","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":68,"referenced_works":["https://openalex.org/W44206081","https://openalex.org/W197578431","https://openalex.org/W225482321","https://openalex.org/W1507388704","https://openalex.org/W1517263647","https://openalex.org/W1557552045","https://openalex.org/W1568060924","https://openalex.org/W1591187753","https://openalex.org/W1595209923","https://openalex.org/W1616592835","https://openalex.org/W1964238319","https://openalex.org/W1971579914","https://openalex.org/W1972161591","https://openalex.org/W1975452052","https://openalex.org/W1976107593","https://openalex.org/W1976603655","https://openalex.org/W1977096973","https://openalex.org/W1977119553","https://openalex.org/W1977666960","https://openalex.org/W1987485489","https://openalex.org/W1988678729","https://openalex.org/W1990839929","https://openalex.org/W1996314390","https://openalex.org/W1999142756","https://openalex.org/W2006811655","https://openalex.org/W2018449570","https://openalex.org/W2020454906","https://openalex.org/W2021471471","https://openalex.org/W2025177979","https://openalex.org/W2025409136","https://openalex.org/W2025540821","https://openalex.org/W2026958285","https://openalex.org/W2029178312","https://openalex.org/W2030092320","https://openalex.org/W2037624113","https://openalex.org/W2040472652","https://openalex.org/W2055992184","https://openalex.org/W2063522960","https://openalex.org/W2069262711","https://openalex.org/W2070889911","https://openalex.org/W2071221524","https://openalex.org/W2072364504","https://openalex.org/W2075277027","https://openalex.org/W2076732675","https://openalex.org/W2084783422","https://openalex.org/W2086331234","https://openalex.org/W2087138692","https://openalex.org/W2091566818","https://openalex.org/W2092750956","https://openalex.org/W2101176165","https://openalex.org/W2108489838","https://openalex.org/W2113457752","https://openalex.org/W2120863112","https://openalex.org/W2128635872","https://openalex.org/W2133492742","https://openalex.org/W2135598278","https://openalex.org/W2139086387","https://openalex.org/W2151438850","https://openalex.org/W2160059044","https://openalex.org/W2161959257","https://openalex.org/W2163506845","https://openalex.org/W2166754951","https://openalex.org/W2314655097","https://openalex.org/W2321040723","https://openalex.org/W2409181930","https://openalex.org/W2486139341","https://openalex.org/W2791114118","https://openalex.org/W6647226646"],"related_works":["https://openalex.org/W2026958285","https://openalex.org/W1975777592","https://openalex.org/W2410265806","https://openalex.org/W3188140296","https://openalex.org/W2022682037","https://openalex.org/W2075007409","https://openalex.org/W1976603655","https://openalex.org/W2001274141","https://openalex.org/W2043139859","https://openalex.org/W2100411666"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}