{"id":"https://openalex.org/W2009011345","doi":"https://doi.org/10.1289/ehp.01109s4523","title":"Ambient particle inhalation and the cardiovascular system: potential mechanisms.","display_name":"Ambient particle inhalation and the cardiovascular system: potential mechanisms.","publication_year":2001,"publication_date":"2001-08-01","ids":{"openalex":"https://openalex.org/W2009011345","doi":"https://doi.org/10.1289/ehp.01109s4523","mag":"2009011345","pmid":"https://pubmed.ncbi.nlm.nih.gov/11544157","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1240575"},"language":"en","primary_location":{"id":"doi:10.1289/ehp.01109s4523","doi":"https://doi.org/10.1289/ehp.01109s4523","is_oa":true,"landing_page_url":"https://doi.org/10.1289/ehp.01109s4523","pdf_url":null,"source":{"id":"https://openalex.org/S10446503","display_name":"Environmental Health Perspectives","issn_l":"0091-6765","issn":["0091-6765","1552-9924"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319799","host_organization_name":"National Institute of Environmental Health Sciences","host_organization_lineage":["https://openalex.org/P4310319799","https://openalex.org/P4310316754"],"host_organization_lineage_names":["National Institute of Environmental Health Sciences","National Institutes of Health"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Health Perspectives","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1289/ehp.01109s4523","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034736085","display_name":"Ken Donaldson","orcid":"https://orcid.org/0000-0002-2093-1852","observed_orcids":["https://orcid.org/0000-0002-2093-1852"]},"institutions":[{"id":"https://openalex.org/I251738","display_name":"Edinburgh Napier University","ror":"https://ror.org/03zjvnn91","country_code":"GB","type":"education","lineage":["https://openalex.org/I251738"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"K Donaldson","raw_affiliation_strings":["Biomedicine Research Group, School of Life Sciences, Napier University, Edinburgh, Scotland. kdonaldson@napier.ac.uk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicine Research Group, School of Life Sciences, Napier University, Edinburgh, Scotland. kdonaldson@napier.ac.uk","institution_ids":["https://openalex.org/I251738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008390045","display_name":"Vicki Stone","orcid":"https://orcid.org/0000-0001-8346-7471","observed_orcids":["https://orcid.org/0000-0001-8346-7471"]},"institutions":[{"id":"https://openalex.org/I251738","display_name":"Edinburgh Napier University","ror":"https://ror.org/03zjvnn91","country_code":"GB","type":"education","lineage":["https://openalex.org/I251738"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"V Stone","raw_affiliation_strings":["Biomedicine Research Group, School of Life Sciences, Napier University, Edinburgh, Scotland. kdonaldson@napier.ac.uk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicine Research Group, School of Life Sciences, Napier University, Edinburgh, Scotland. kdonaldson@napier.ac.uk","institution_ids":["https://openalex.org/I251738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012983949","display_name":"Anthony Seaton","orcid":"https://orcid.org/0000-0002-8640-2523","observed_orcids":["https://orcid.org/0000-0002-8640-2523"]},"institutions":[{"id":"https://openalex.org/I251738","display_name":"Edinburgh Napier University","ror":"https://ror.org/03zjvnn91","country_code":"GB","type":"education","lineage":["https://openalex.org/I251738"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A Seaton","raw_affiliation_strings":["Biomedicine Research Group, School of Life Sciences, Napier University, Edinburgh, Scotland. kdonaldson@napier.ac.uk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicine Research Group, School of Life Sciences, Napier University, Edinburgh, Scotland. kdonaldson@napier.ac.uk","institution_ids":["https://openalex.org/I251738"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050425677","display_name":"William MacNee","orcid":"https://orcid.org/0000-0002-3692-1448","observed_orcids":["https://orcid.org/0000-0002-3692-1448"]},"institutions":[{"id":"https://openalex.org/I251738","display_name":"Edinburgh Napier University","ror":"https://ror.org/03zjvnn91","country_code":"GB","type":"education","lineage":["https://openalex.org/I251738"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"W MacNee","raw_affiliation_strings":["Biomedicine Research Group, School of Life Sciences, Napier University, Edinburgh, Scotland. kdonaldson@napier.ac.uk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicine Research Group, School of Life Sciences, Napier University, Edinburgh, Scotland. kdonaldson@napier.ac.uk","institution_ids":["https://openalex.org/I251738"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I251738"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":{"value":4500,"currency":"USD","value_usd":4500},"fwci":13.1489,"has_fulltext":true,"cited_by_count":649,"citation_normalized_percentile":{"value":0.99516441,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"109","issue":"suppl 4","first_page":"523","last_page":"527"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10190","display_name":"Air Quality and Health Impacts","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10190","display_name":"Air Quality and Health Impacts","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11002","display_name":"Indoor Air Quality and Microbial Exposure","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10075","display_name":"Atmospheric chemistry and aerosols","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1902","display_name":"Atmospheric Science"},"field":{"id":"https://openalex.org/fields/19","display_name":"Earth and Planetary Sciences"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ultrafine-particles","display_name":"ultrafine particles","score":0.9589999914169312},{"id":"https://openalex.org/keywords/particulate-matter","display_name":"particulate matter","score":0.8669999837875366},{"id":"https://openalex.org/keywords/air-pollution","display_name":"air pollution","score":0.824999988079071},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.9520000219345093},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.8069999814033508},{"id":"https://openalex.org/keywords/calcium-influx","display_name":"calcium influx","score":0.9850000143051147},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9980000257492065},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.734000027179718},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.8410000205039978},{"id":"https://openalex.org/keywords/acute-phase-response","display_name":"acute phase response","score":0.8849999904632568},{"id":"https://openalex.org/keywords/blood-viscosity","display_name":"blood viscosity","score":0.8289999961853027},{"id":"https://openalex.org/keywords/fibrinogen","display_name":"fibrinogen","score":0.8349999785423279},{"id":"https://openalex.org/keywords/heart-rate","display_name":"heart rate","score":0.7310000061988831},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.5210000276565552},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.6000000238418579}],"concepts":[{"id":"https://openalex.org/C150032891","wikidata":"https://www.wikidata.org/wiki/Q7880535","display_name":"Ultrafine particle","level":2,"score":0.7052363753318787},{"id":"https://openalex.org/C24245907","wikidata":"https://www.wikidata.org/wiki/Q498957","display_name":"Particulates","level":2,"score":0.6427656412124634},{"id":"https://openalex.org/C2779777708","wikidata":"https://www.wikidata.org/wiki/Q6033622","display_name":"Inhalation exposure","level":3,"score":0.628778338432312},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5905984044075012},{"id":"https://openalex.org/C559116025","wikidata":"https://www.wikidata.org/wiki/Q131123","display_name":"Air pollution","level":2,"score":0.5829415917396545},{"id":"https://openalex.org/C2776954882","wikidata":"https://www.wikidata.org/wiki/Q840343","display_name":"Inhalation","level":2,"score":0.4990577697753906},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4744126498699188},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.4684203863143921},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.4564535617828369},{"id":"https://openalex.org/C2779036427","wikidata":"https://www.wikidata.org/wiki/Q381899","display_name":"Fibrinogen","level":2,"score":0.4249122738838196},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.39832988381385803},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.38905951380729675},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3342491686344147},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3074183464050293},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2598661780357361},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18878650665283203},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.10832065343856812},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.1006399393081665},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000393","descriptor_name":"Air Pollutants","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000397","descriptor_name":"Air Pollution","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1289/ehp.01109s4523","doi":"https://doi.org/10.1289/ehp.01109s4523","is_oa":true,"landing_page_url":"https://doi.org/10.1289/ehp.01109s4523","pdf_url":null,"source":{"id":"https://openalex.org/S10446503","display_name":"Environmental Health Perspectives","issn_l":"0091-6765","issn":["0091-6765","1552-9924"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319799","host_organization_name":"National Institute of Environmental Health Sciences","host_organization_lineage":["https://openalex.org/P4310319799","https://openalex.org/P4310316754"],"host_organization_lineage_names":["National Institute of Environmental Health Sciences","National Institutes of Health"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Health Perspectives","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:216875","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1240575","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1240575","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1240575","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environ Health Perspect","raw_type":"Text"},{"id":"pmh:oai:pure.ed.ac.uk:openaire/256e921d-08ef-4502-875d-9a1cc63059fd","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1240575","pdf_url":null,"source":{"id":"https://openalex.org/S4306400321","display_name":"Edinburgh Research Explorer (University of Edinburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I98677209","host_organization_name":"University of Edinburgh","host_organization_lineage":["https://openalex.org/I98677209"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Donaldson, K, Stone, V, Seaton, A & Macnee, W 2001, 'Ambient particle inhalation and the cardiovascular system: potential mechanisms', Environmental Health Perspectives, vol. 109, no. Suppl 4, pp. 523-7. < http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240575/ >","raw_type":"info:eu-repo/semantics/article"},{"id":"pmid:11544157","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11544157","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental health perspectives","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1289/ehp.01109s4523","doi":"https://doi.org/10.1289/ehp.01109s4523","is_oa":true,"landing_page_url":"https://doi.org/10.1289/ehp.01109s4523","pdf_url":null,"source":{"id":"https://openalex.org/S10446503","display_name":"Environmental Health Perspectives","issn_l":"0091-6765","issn":["0091-6765","1552-9924"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319799","host_organization_name":"National Institute of Environmental Health Sciences","host_organization_lineage":["https://openalex.org/P4310319799","https://openalex.org/P4310316754"],"host_organization_lineage_names":["National Institute of Environmental Health Sciences","National Institutes of Health"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Health Perspectives","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320055","display_name":"British Lung Foundation","ror":"https://ror.org/05qnwyb92"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W1954124","https://openalex.org/W73499109","https://openalex.org/W236838239","https://openalex.org/W1480792445","https://openalex.org/W1552363142","https://openalex.org/W1650401181","https://openalex.org/W1678210387","https://openalex.org/W1970867120","https://openalex.org/W1975672902","https://openalex.org/W1990285596","https://openalex.org/W1991880580","https://openalex.org/W1994885237","https://openalex.org/W2002884360","https://openalex.org/W2005598261","https://openalex.org/W2011589019","https://openalex.org/W2018294565","https://openalex.org/W2024772477","https://openalex.org/W2026811587","https://openalex.org/W2027632610","https://openalex.org/W2029890768","https://openalex.org/W2035839412","https://openalex.org/W2040066643","https://openalex.org/W2056658522","https://openalex.org/W2068161960","https://openalex.org/W2069268909","https://openalex.org/W2076964782","https://openalex.org/W2081893638","https://openalex.org/W2094513619","https://openalex.org/W2100068043","https://openalex.org/W2101306218","https://openalex.org/W2104485773","https://openalex.org/W2107080012","https://openalex.org/W2108071067","https://openalex.org/W2109111756","https://openalex.org/W2134894453","https://openalex.org/W2135297085","https://openalex.org/W2144679128","https://openalex.org/W2148562253","https://openalex.org/W2151087479","https://openalex.org/W2156895145","https://openalex.org/W2158000994","https://openalex.org/W2161528133","https://openalex.org/W2165298408","https://openalex.org/W2183115385","https://openalex.org/W2395147993","https://openalex.org/W2416022024","https://openalex.org/W2419364902","https://openalex.org/W3058700394","https://openalex.org/W4248285292"],"related_works":["https://openalex.org/W7100964270","https://openalex.org/W2035839412","https://openalex.org/W2228048694","https://openalex.org/W7100730179","https://openalex.org/W2105065756","https://openalex.org/W2023968391","https://openalex.org/W1578041684","https://openalex.org/W2977957754","https://openalex.org/W2354750581","https://openalex.org/W1799079720"],"abstract_inverted_index":{"Well-documented":[0],"air":[1,22,49,169,175,197],"pollution":[2,23,176,198],"episodes":[3],"throughout":[4],"recent":[5],"history":[6],"have":[7,107,115,199,209],"led":[8],"to":[9,96,119,131,174,195],"deaths":[10],"among":[11],"individuals":[12,32,207],"with":[13,66,125,167],"cardiovascular":[14,247],"and":[15,89,157,163,181,202,246],"respiratory":[16],"disease.":[17,248],"Although":[18],"the":[19,26,47,81,135,154,235,239,242],"components":[20],"of":[21,46,63,80,161,216,227],"that":[24],"cause":[25],"adverse":[27,82,108],"health":[28,83],"effects":[29,84,109],"in":[30,58,86,153,190,193,206,223],"these":[31,113],"are":[33,51,158,203],"unknown,":[34,111],"a":[35,41,67],"small":[36],"proportion":[37,43],"by":[38,44,103,143,146],"mass":[39,68],"but":[40,112],"large":[42],"number":[45],"ambient":[48],"particles":[50,106,114,241],"ultrafine,":[52],"i.e.,":[53],"less":[54,72],"than":[55,73],"100":[56],"nm":[57],"diameter.":[59],"This":[60],"ultrafine":[61,105,240],"component":[62],"particulate":[64,168],"matter":[65],"median":[69],"aerodynamic":[70],"diameter":[71],"10":[74],"microm":[75],"(PM(10)":[76],"may":[77],"mediate":[78],"some":[79],"reported":[85],"epidemiologic":[87],"studies":[88],"for":[90],"which":[91,104],"there":[92,219],"is":[93,110,129],"toxicologic":[94],"evidence":[95],"support":[97],"this":[98,139,230],"contention.":[99],"The":[100],"exact":[101],"mechanism":[102],"recently":[116],"been":[117,200],"shown":[118],"enhance":[120],"calcium":[121],"influx":[122],"on":[123],"contact":[124],"macrophages.":[126],"Oxidative":[127],"stress":[128],"also":[130],"be":[132,141],"anticipated":[133],"at":[134],"huge":[136],"particle":[137],"surface;":[138],"can":[140],"augmented":[142],"oxidants":[144],"generated":[145],"recruited":[147],"inflammatory":[148],"leukocytes.":[149],"Atheromatous":[150],"plaques":[151],"form":[152],"coronary":[155],"arteries":[156],"major":[159],"causes":[160],"morbidity":[162],"death":[164],"associated":[165],"epidemiologically":[166],"pollution.":[170],"In":[171,213,229],"populations":[172],"exposed":[173],"episodes,":[177],"blood":[178,211],"viscosity,":[179],"fibrinogen,":[180],"C-reactive":[182],"protein":[183],"(CRP)":[184],"were":[185,220],"higher.":[186],"More":[187],"recently,":[188],"increases":[189],"heart":[191],"rate":[192],"response":[194,245],"rising":[196],"described":[201],"most":[204],"marked":[205],"who":[208],"high":[210],"viscosity.":[212],"our":[214],"study":[215],"elderly":[217],"individuals,":[218],"significant":[221],"rises":[222],"CRP,":[224],"an":[225],"index":[226],"inflammation.":[228],"present":[231],"review,":[232],"we":[233],"consider":[234],"likely":[236],"interactions":[237],"between":[238],"acute":[243],"phase":[244]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":26},{"year":2022,"cited_by_count":24},{"year":2021,"cited_by_count":31},{"year":2020,"cited_by_count":26},{"year":2019,"cited_by_count":37},{"year":2018,"cited_by_count":22},{"year":2017,"cited_by_count":26},{"year":2016,"cited_by_count":27},{"year":2015,"cited_by_count":32},{"year":2014,"cited_by_count":29},{"year":2013,"cited_by_count":33},{"year":2012,"cited_by_count":33}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}