{"id":"https://openalex.org/W2009005264","doi":"https://doi.org/10.1177/074873099129000669","title":"Seasonal Variation of Blood Cholesterol Levels: Study Methodology","display_name":"Seasonal Variation of Blood Cholesterol Levels: Study Methodology","publication_year":1999,"publication_date":"1999-08-01","ids":{"openalex":"https://openalex.org/W2009005264","doi":"https://doi.org/10.1177/074873099129000669","mag":"2009005264","pmid":"https://pubmed.ncbi.nlm.nih.gov/10447314"},"language":"en","primary_location":{"id":"doi:10.1177/074873099129000669","doi":"https://doi.org/10.1177/074873099129000669","is_oa":false,"landing_page_url":"https://doi.org/10.1177/074873099129000669","pdf_url":null,"source":{"id":"https://openalex.org/S192515372","display_name":"Journal of Biological Rhythms","issn_l":"0748-7304","issn":["0748-7304","1552-4531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Rhythms","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113618396","display_name":"Philip A. Merriam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Philip A. Merriam","raw_affiliation_strings":["Division of Preventive and Behavioral Medicine, University of Massachusetts Medical School, Department of Medicine, 55 Lake Avenue North, Worcester, MA 01655"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Preventive and Behavioral Medicine, University of Massachusetts Medical School, Department of Medicine, 55 Lake Avenue North, Worcester, MA 01655","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080466261","display_name":"Ira S. Ockene","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ira S. Ockene","raw_affiliation_strings":["Division of Cardiovascular Medicine, University of Massachusetts Medical School, Department of Medicine, 55 Lake Avenue North, Worcester, MA 01655"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Medicine, University of Massachusetts Medical School, Department of Medicine, 55 Lake Avenue North, Worcester, MA 01655","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038298202","display_name":"James R. H\u00e9bert","orcid":"https://orcid.org/0000-0002-0677-2672","observed_orcids":["https://orcid.org/0000-0002-0677-2672"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"James R. Hebert","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072977071","display_name":"Milagros C. Rosal","orcid":"https://orcid.org/0000-0001-8497-5558","observed_orcids":["https://orcid.org/0000-0001-8497-5558"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Milagros C. Rosal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5054480104","display_name":"Charles Edwards Matthews","orcid":"https://orcid.org/0000-0001-8037-3103","observed_orcids":["https://orcid.org/0000-0001-8037-3103"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles E. Matthews","raw_affiliation_strings":["Division of Preventive and Behavioral Medicine, University of Massachusetts Medical School, Department of Medicine, 55 Lake Avenue North, Worcester, MA 01655"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Preventive and Behavioral Medicine, University of Massachusetts Medical School, Department of Medicine, 55 Lake Avenue North, Worcester, MA 01655","institution_ids":["https://openalex.org/I166722992"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4400,"currency":"USD","value_usd":4400},"apc_paid":null,"fwci":1.6851,"has_fulltext":false,"cited_by_count":49,"citation_normalized_percentile":{"value":0.84548822,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"14","issue":"4","first_page":"330","last_page":"339"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.8281000256538391,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.8281000256538391,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.04390000179409981,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.024399999529123306,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/seasonal-variation","display_name":"seasonal variation","score":0.9789999723434448},{"id":"https://openalex.org/keywords/serum-cholesterol","display_name":"serum cholesterol","score":0.9900000095367432},{"id":"https://openalex.org/keywords/serum-lipids","display_name":"serum lipids","score":0.9819999933242798},{"id":"https://openalex.org/keywords/covariates","display_name":"covariates","score":0.7289999723434448},{"id":"https://openalex.org/keywords/general-population","display_name":"general population","score":0.6269999742507935}],"concepts":[{"id":"https://openalex.org/C125403950","wikidata":"https://www.wikidata.org/wiki/Q2111082","display_name":"Seasonality","level":2,"score":0.8520717620849609},{"id":"https://openalex.org/C2778334786","wikidata":"https://www.wikidata.org/wiki/Q1586270","display_name":"Variation (astronomy)","level":2,"score":0.711544394493103},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.453773558139801},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3952144384384155},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.36269646883010864},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.2703648805618286},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.11553841829299927},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C44870925","wikidata":"https://www.wikidata.org/wiki/Q37547","display_name":"Astrophysics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D002791","descriptor_name":"Cholesterol, Dietary","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005082","descriptor_name":"Physical Exertion","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006854","descriptor_name":"Hydrocortisone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008027","descriptor_name":"Light","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008685","descriptor_name":"Meteorological Concepts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012621","descriptor_name":"Seasons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1177/074873099129000669","doi":"https://doi.org/10.1177/074873099129000669","is_oa":false,"landing_page_url":"https://doi.org/10.1177/074873099129000669","pdf_url":null,"source":{"id":"https://openalex.org/S192515372","display_name":"Journal of Biological Rhythms","issn_l":"0748-7304","issn":["0748-7304","1552-4531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Rhythms","raw_type":"journal-article"},{"id":"pmid:10447314","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10447314","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biological rhythms","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.865.194","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.865.194","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jbr.sagepub.com/content/14/4/330.full.pdf","raw_type":"text"},{"id":"pmh:oai:escholarship.umassmed.edu:cardio_pp-1088","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.umassmed.edu/cardio_pp/72","pdf_url":null,"source":{"id":"https://openalex.org/S4306400883","display_name":"The Journal of the American Medical Association (JAMA) Network (American Medical Association)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I173654999","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/I173654999"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cardiovascular Medicine Publications","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3416511668","display_name":"SEASONAL VARIATION OF BLOOD CHOLESTEROL LEVELS","funder_award_id":"R01HL052745","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W152438652","https://openalex.org/W159496879","https://openalex.org/W1970147997","https://openalex.org/W1971306695","https://openalex.org/W1983266070","https://openalex.org/W1985085932","https://openalex.org/W1995645776","https://openalex.org/W1996291797","https://openalex.org/W1996299251","https://openalex.org/W2019937941","https://openalex.org/W2021804141","https://openalex.org/W2026858292","https://openalex.org/W2029415788","https://openalex.org/W2031134017","https://openalex.org/W2040532571","https://openalex.org/W2045065444","https://openalex.org/W2056139633","https://openalex.org/W2056814312","https://openalex.org/W2058042304","https://openalex.org/W2059305764","https://openalex.org/W2067495470","https://openalex.org/W2067684886","https://openalex.org/W2073973921","https://openalex.org/W2074079685","https://openalex.org/W2075110081","https://openalex.org/W2086195034","https://openalex.org/W2086543045","https://openalex.org/W2091887806","https://openalex.org/W2092179956","https://openalex.org/W2097146819","https://openalex.org/W2097184022","https://openalex.org/W2097222394","https://openalex.org/W2105472095","https://openalex.org/W2106558822","https://openalex.org/W2110356839","https://openalex.org/W2112888162","https://openalex.org/W2120996730","https://openalex.org/W2135433798","https://openalex.org/W2184589130","https://openalex.org/W2273376892","https://openalex.org/W2327530675","https://openalex.org/W2408019215","https://openalex.org/W2418383315","https://openalex.org/W2788450175","https://openalex.org/W2799732451","https://openalex.org/W4238079920","https://openalex.org/W4249825849"],"related_works":["https://openalex.org/W7095971651","https://openalex.org/W6939866788","https://openalex.org/W2396785184","https://openalex.org/W6939841870","https://openalex.org/W1978853058","https://openalex.org/W1971306695","https://openalex.org/W2414114219","https://openalex.org/W3025830122","https://openalex.org/W2084156681","https://openalex.org/W1996291797"],"abstract_inverted_index":{"This":[0,67],"manuscript":[1],"provides":[2],"a":[3,35,78],"description":[4],"of":[5,13,22,27,45,56,59,80,88],"the":[6,10,20,24,28,46,54,64,86],"methodology":[7],"used":[8],"in":[9,39,63,90],"Seasonal":[11],"Variation":[12],"Blood":[14],"Cholesterol":[15],"Levels":[16],"(SEASON)":[17],"study,":[18],"with":[19,37],"intent":[21],"informing":[23],"scientific":[25],"community":[26],"available":[29],"data":[30],"sets":[31],"and":[32,52,76,93],"to":[33,50,73,84],"invite":[34],"dialogue":[36],"scientists":[38],"complementary":[40],"fields.":[41],"The":[42],"primary":[43],"aim":[44],"SEASON":[47],"study":[48,85],"is":[49,70],"describe":[51],"delineate":[53],"causes":[55],"seasonal":[57],"variation":[58],"blood":[60,91],"lipid":[61],"levels":[62],"general":[65],"population.":[66],"research":[68],"project":[69],"designed":[71],"specifically":[72],"systematically":[74],"collect":[75],"analyze":[77],"number":[79],"important":[81],"variables":[82],"necessary":[83],"role":[87],"seasonality":[89],"lipids":[92],"relevant":[94],"covariates.":[95]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}