{"id":"https://openalex.org/W2008928656","doi":"https://doi.org/10.1155/2014/859817","title":"Hematopoietic and Mesenchymal Stem Cells for the Treatment of Chronic Respiratory Diseases: Role of Plasticity and Heterogeneity","display_name":"Hematopoietic and Mesenchymal Stem Cells for the Treatment of Chronic Respiratory Diseases: Role of Plasticity and Heterogeneity","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2008928656","doi":"https://doi.org/10.1155/2014/859817","mag":"2008928656","pmid":"https://pubmed.ncbi.nlm.nih.gov/24563632","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3916026"},"language":"en","primary_location":{"id":"doi:10.1155/2014/859817","doi":"https://doi.org/10.1155/2014/859817","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2014/859817","pdf_url":"https://downloads.hindawi.com/journals/tswj/2014/859817.pdf","source":{"id":"https://openalex.org/S29243050","display_name":"The Scientific World JOURNAL","issn_l":"1537-744X","issn":["1537-744X","2356-6140"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Scientific World Journal","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://downloads.hindawi.com/journals/tswj/2014/859817.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019256300","display_name":"Massimo Conese","orcid":"https://orcid.org/0000-0003-3465-6641","observed_orcids":["https://orcid.org/0000-0003-3465-6641"]},"institutions":[{"id":"https://openalex.org/I106296451","display_name":"University of Foggia","ror":"https://ror.org/01xtv3204","country_code":"IT","type":"education","lineage":["https://openalex.org/I106296451"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Massimo Conese","raw_affiliation_strings":["Department of Medical and Surgical Sciences, University of Foggia, Viale L. Pinto 1, 71122 Foggia, Italy"],"raw_orcid":"https://orcid.org/0000-0003-3465-6641","affiliations":[{"raw_affiliation_string":"Department of Medical and Surgical Sciences, University of Foggia, Viale L. Pinto 1, 71122 Foggia, Italy","institution_ids":["https://openalex.org/I106296451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039768616","display_name":"Donatella Piro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I106296451","display_name":"University of Foggia","ror":"https://ror.org/01xtv3204","country_code":"IT","type":"education","lineage":["https://openalex.org/I106296451"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Donatella Piro","raw_affiliation_strings":["Department of Medical and Surgical Sciences, University of Foggia, Viale L. Pinto 1, 71122 Foggia, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical and Surgical Sciences, University of Foggia, Viale L. Pinto 1, 71122 Foggia, Italy","institution_ids":["https://openalex.org/I106296451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013039943","display_name":"Annalucia Carbone","orcid":"https://orcid.org/0000-0002-8402-3298","observed_orcids":["https://orcid.org/0000-0002-8402-3298"]},"institutions":[{"id":"https://openalex.org/I106296451","display_name":"University of Foggia","ror":"https://ror.org/01xtv3204","country_code":"IT","type":"education","lineage":["https://openalex.org/I106296451"]},{"id":"https://openalex.org/I2803066834","display_name":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico","ror":"https://ror.org/016zn0y21","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I189158943","https://openalex.org/I2803066834","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Annalucia Carbone","raw_affiliation_strings":["Department of Medical and Surgical Sciences, University of Foggia, Viale L. Pinto 1, 71122 Foggia, Italy","Medical Genetics Laboratory, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Commenda 12, 20122 Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical and Surgical Sciences, University of Foggia, Viale L. Pinto 1, 71122 Foggia, Italy","institution_ids":["https://openalex.org/I106296451"]},{"raw_affiliation_string":"Medical Genetics Laboratory, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Commenda 12, 20122 Milan, Italy","institution_ids":["https://openalex.org/I2803066834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024430695","display_name":"Stefano Castellani","orcid":"https://orcid.org/0000-0003-0201-7298","observed_orcids":["https://orcid.org/0000-0003-0201-7298"]},"institutions":[{"id":"https://openalex.org/I106296451","display_name":"University of Foggia","ror":"https://ror.org/01xtv3204","country_code":"IT","type":"education","lineage":["https://openalex.org/I106296451"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Stefano Castellani","raw_affiliation_strings":["Department of Medical and Surgical Sciences, University of Foggia, Viale L. Pinto 1, 71122 Foggia, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical and Surgical Sciences, University of Foggia, Viale L. Pinto 1, 71122 Foggia, Italy","institution_ids":["https://openalex.org/I106296451"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002655593","display_name":"Sante Di Gioia","orcid":"https://orcid.org/0000-0001-7246-5622","observed_orcids":["https://orcid.org/0000-0001-7246-5622"]},"institutions":[{"id":"https://openalex.org/I106296451","display_name":"University of Foggia","ror":"https://ror.org/01xtv3204","country_code":"IT","type":"education","lineage":["https://openalex.org/I106296451"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Sante Di Gioia","raw_affiliation_strings":["Department of Medical and Surgical Sciences, University of Foggia, Viale L. Pinto 1, 71122 Foggia, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical and Surgical Sciences, University of Foggia, Viale L. Pinto 1, 71122 Foggia, Italy","institution_ids":["https://openalex.org/I106296451"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5019256300"],"corresponding_institution_ids":["https://openalex.org/I106296451"],"apc_list":{"value":860,"currency":"USD","value_usd":860},"apc_paid":{"value":860,"currency":"USD","value_usd":860},"fwci":0.4724,"has_fulltext":true,"cited_by_count":27,"citation_normalized_percentile":{"value":0.39798658,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"2014","issue":null,"first_page":"1","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.007000000216066837,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hematopoietic-stem-and-progenitor-cells","display_name":"hematopoietic stem and progenitor cells","score":0.9419999718666077},{"id":"https://openalex.org/keywords/mesenchymal-stem-cells","display_name":"mesenchymal stem cells","score":0.9649999737739563},{"id":"https://openalex.org/keywords/stem-cell-plasticity","display_name":"stem cell plasticity","score":0.8339999914169312},{"id":"https://openalex.org/keywords/chronic-lung-disease","display_name":"chronic lung disease","score":0.8050000071525574},{"id":"https://openalex.org/keywords/cystic-fibrosis","display_name":"cystic fibrosis","score":0.9789999723434448},{"id":"https://openalex.org/keywords/asthma","display_name":"asthma","score":0.9959999918937683},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bone-marrow-derived-stem-cells","display_name":"bone marrow-derived stem cells","score":0.8140000104904175},{"id":"https://openalex.org/keywords/engraftment","display_name":"engraftment","score":0.7599999904632568},{"id":"https://openalex.org/keywords/lung-regeneration","display_name":"lung regeneration","score":0.703000009059906},{"id":"https://openalex.org/keywords/stem-cell-heterogeneity","display_name":"stem cell heterogeneity","score":0.8090000152587891},{"id":"https://openalex.org/keywords/regenerative-medicine","display_name":"regenerative medicine","score":0.6480000019073486},{"id":"https://openalex.org/keywords/cell-therapy","display_name":"cell therapy","score":0.3700000047683716}],"concepts":[{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.7637326717376709},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.718346118927002},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.6204186081886292},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.5804774761199951},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.568600594997406},{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.4907287359237671},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.49019676446914673},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.48091456294059753},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4776531457901001},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4587538242340088},{"id":"https://openalex.org/C2779389132","wikidata":"https://www.wikidata.org/wiki/Q1533033","display_name":"Stem-cell therapy","level":3,"score":0.4560418725013733},{"id":"https://openalex.org/C143441281","wikidata":"https://www.wikidata.org/wiki/Q5133858","display_name":"Clinical uses of mesenchymal stem cells","level":5,"score":0.44616997241973877},{"id":"https://openalex.org/C2777408962","wikidata":"https://www.wikidata.org/wiki/Q1128050","display_name":"Hematopoietic stem cell transplantation","level":3,"score":0.422094464302063},{"id":"https://openalex.org/C20875687","wikidata":"https://www.wikidata.org/wiki/Q2642600","display_name":"Adult stem cell","level":4,"score":0.4099193513393402},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3086986541748047},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.27268698811531067},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.23988190293312073},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.12920266389846802},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08171415328979492},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002908","descriptor_name":"Chronic Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008171","descriptor_name":"Lung Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008171","descriptor_name":"Lung Diseases","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D012120","descriptor_name":"Respiration Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012120","descriptor_name":"Respiration Disorders","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D018380","descriptor_name":"Hematopoietic Stem Cell Transplantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D044968","descriptor_name":"Regenerative Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D044968","descriptor_name":"Regenerative Medicine","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":false},{"descriptor_ui":"D045164","descriptor_name":"Mesenchymal Stem Cell Transplantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.1155/2014/859817","doi":"https://doi.org/10.1155/2014/859817","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2014/859817","pdf_url":"https://downloads.hindawi.com/journals/tswj/2014/859817.pdf","source":{"id":"https://openalex.org/S29243050","display_name":"The Scientific World JOURNAL","issn_l":"1537-744X","issn":["1537-744X","2356-6140"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Scientific World Journal","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2913254","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3916026","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:24563632","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24563632","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"TheScientificWorldJournal","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3916026","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3916026/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ScientificWorldJournal","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.870.8473","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.870.8473","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://europepmc.org/backend/ptpmcrender.fcgi?accid%3DPMC3916026%26blobtype%3Dpdf","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:f53f38919a7142fc8f34ba3c5dd34005","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/f53f38919a7142fc8f34ba3c5dd34005","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Scientific World Journal, Vol 2014 (2014)","raw_type":"article"},{"id":"pmh:oai:iris.unica.it:11584/98276","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11584/98276","pdf_url":null,"source":{"id":"https://openalex.org/S4377196293","display_name":"UNICA IRIS Institutional Research Information System (University of Cagliari)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I172446870","host_organization_name":"University of Cagliari","host_organization_lineage":["https://openalex.org/I172446870"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1155/2014/859817","doi":"https://doi.org/10.1155/2014/859817","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2014/859817","pdf_url":"https://downloads.hindawi.com/journals/tswj/2014/859817.pdf","source":{"id":"https://openalex.org/S29243050","display_name":"The Scientific World JOURNAL","issn_l":"1537-744X","issn":["1537-744X","2356-6140"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Scientific World Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306168","display_name":"Cystic Fibrosis Foundation","ror":"https://ror.org/00ax59295"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2008928656.pdf","grobid_xml":"https://content.openalex.org/works/W2008928656.grobid-xml"},"referenced_works_count":145,"referenced_works":["https://openalex.org/W135317861","https://openalex.org/W1482672078","https://openalex.org/W1485469081","https://openalex.org/W1533266221","https://openalex.org/W1535560730","https://openalex.org/W1570160369","https://openalex.org/W1582606058","https://openalex.org/W1925664769","https://openalex.org/W1963729602","https://openalex.org/W1965425745","https://openalex.org/W1967524272","https://openalex.org/W1971329978","https://openalex.org/W1975477723","https://openalex.org/W1976895035","https://openalex.org/W1978370369","https://openalex.org/W1978957262","https://openalex.org/W1979155684","https://openalex.org/W1979844007","https://openalex.org/W1980105210","https://openalex.org/W1980419256","https://openalex.org/W1981302659","https://openalex.org/W1981654793","https://openalex.org/W1981681632","https://openalex.org/W1983545746","https://openalex.org/W1984804160","https://openalex.org/W1984850507","https://openalex.org/W1989543257","https://openalex.org/W1991279353","https://openalex.org/W1996763820","https://openalex.org/W1997675408","https://openalex.org/W2000584719","https://openalex.org/W2001675896","https://openalex.org/W2002248781","https://openalex.org/W2002386116","https://openalex.org/W2003502792","https://openalex.org/W2003976042","https://openalex.org/W2006088733","https://openalex.org/W2007502830","https://openalex.org/W2010324163","https://openalex.org/W2011712807","https://openalex.org/W2012323396","https://openalex.org/W2015130081","https://openalex.org/W2016073678","https://openalex.org/W2016363536","https://openalex.org/W2016823790","https://openalex.org/W2017418598","https://openalex.org/W2017530043","https://openalex.org/W2020460921","https://openalex.org/W2021183752","https://openalex.org/W2023339317","https://openalex.org/W2024562705","https://openalex.org/W2027703497","https://openalex.org/W2030198326","https://openalex.org/W2032847865","https://openalex.org/W2037298492","https://openalex.org/W2039813966","https://openalex.org/W2040612034","https://openalex.org/W2040788701","https://openalex.org/W2040959498","https://openalex.org/W2041136998","https://openalex.org/W2042583859","https://openalex.org/W2043865547","https://openalex.org/W2044782007","https://openalex.org/W2047003893","https://openalex.org/W2048258494","https://openalex.org/W2048514182","https://openalex.org/W2050649841","https://openalex.org/W2050774740","https://openalex.org/W2050788263","https://openalex.org/W2055289656","https://openalex.org/W2056258485","https://openalex.org/W2056598800","https://openalex.org/W2056920235","https://openalex.org/W2059972556","https://openalex.org/W2062037030","https://openalex.org/W2062644789","https://openalex.org/W2064412759","https://openalex.org/W2065473309","https://openalex.org/W2068043688","https://openalex.org/W2068527759","https://openalex.org/W2069580663","https://openalex.org/W2073018806","https://openalex.org/W2075801822","https://openalex.org/W2078749608","https://openalex.org/W2083653153","https://openalex.org/W2083916238","https://openalex.org/W2085620217","https://openalex.org/W2085756645","https://openalex.org/W2085868655","https://openalex.org/W2087804062","https://openalex.org/W2090786449","https://openalex.org/W2093870649","https://openalex.org/W2094992482","https://openalex.org/W2095966606","https://openalex.org/W2101116554","https://openalex.org/W2104198623","https://openalex.org/W2104629765","https://openalex.org/W2105734762","https://openalex.org/W2108626209","https://openalex.org/W2110629521","https://openalex.org/W2110918038","https://openalex.org/W2111759041","https://openalex.org/W2111797194","https://openalex.org/W2112041130","https://openalex.org/W2112334970","https://openalex.org/W2116352515","https://openalex.org/W2123920825","https://openalex.org/W2124515706","https://openalex.org/W2125556872","https://openalex.org/W2126763289","https://openalex.org/W2130402304","https://openalex.org/W2132484800","https://openalex.org/W2133375451","https://openalex.org/W2138946470","https://openalex.org/W2140429451","https://openalex.org/W2141041714","https://openalex.org/W2146906484","https://openalex.org/W2146963217","https://openalex.org/W2147156629","https://openalex.org/W2148186686","https://openalex.org/W2150103989","https://openalex.org/W2151937777","https://openalex.org/W2152414109","https://openalex.org/W2154733572","https://openalex.org/W2155697275","https://openalex.org/W2155842880","https://openalex.org/W2158048826","https://openalex.org/W2164730783","https://openalex.org/W2166019746","https://openalex.org/W2168221215","https://openalex.org/W2168757635","https://openalex.org/W2170749916","https://openalex.org/W2171324765","https://openalex.org/W2226125966","https://openalex.org/W2273971600","https://openalex.org/W2323917163","https://openalex.org/W2328808046","https://openalex.org/W2371711026","https://openalex.org/W2397917243","https://openalex.org/W2415536039","https://openalex.org/W2579635034","https://openalex.org/W3106798016","https://openalex.org/W4232062747","https://openalex.org/W4241884576","https://openalex.org/W4292166591"],"related_works":["https://openalex.org/W7098305305","https://openalex.org/W2010239373","https://openalex.org/W3172779388","https://openalex.org/W2002386116","https://openalex.org/W2119849749","https://openalex.org/W2144099229","https://openalex.org/W1991884870","https://openalex.org/W2528396128","https://openalex.org/W2116743066","https://openalex.org/W2065891017"],"abstract_inverted_index":{"Chronic":[0],"lung":[1,64,70,73,188],"diseases,":[2],"such":[3],"as":[4,58,60],"cystic":[5],"fibrosis":[6],"(CF),":[7],"asthma,":[8],"and":[9,17,48,66,77,88,104,122,135],"chronic":[10,69],"obstructive":[11],"pulmonary":[12],"disease":[13],"(COPD)":[14],"are":[15],"incurable":[16],"represent":[18,28],"a":[19,29,111,156,173],"very":[20],"high":[21],"social":[22],"burden.":[23],"Stem":[24],"cell-based":[25],"treatment":[26],"may":[27,133],"hope":[30],"for":[31,187],"the":[32,42,46,56,78,93,146,160,165,168,178],"cure":[33],"of":[34,50,68,80,92,114,120,148,162,167,180],"these":[35,81],"diseases.":[36,71,189],"In":[37],"this":[38,149],"paper,":[39],"we":[40],"revise":[41],"overall":[43],"knowledge":[44],"about":[45],"plasticity":[47,163],"engraftment":[49,121],"exogenous":[51],"marrow-derived":[52,96],"stem":[53,97,169],"cells":[54,102,108,130,141],"into":[55],"lung,":[57],"well":[59],"their":[61],"usefulness":[62],"in":[63,184],"repair":[65],"therapy":[67],"The":[72],"is":[74,83,151],"easily":[75],"accessible":[76],"pathophysiology":[79],"diseases":[82],"characterized":[84],"by":[85,90],"injury,":[86],"inflammation,":[87],"eventually":[89],"remodeling":[91],"airways.":[94],"Bone":[95],"cells,":[98],"including":[99],"hematopoietic":[100],"stem/progenitor":[101],"(HSPCs)":[103],"mesenchymal":[105],"stromal":[106],"(stem)":[107],"(MSCs),":[109],"encompass":[110],"wide":[112],"array":[113],"cell":[115,170],"subsets":[116],"with":[117],"different":[118],"capacities":[119],"injured":[123],"tissue":[124],"regenerating":[125],"potential.":[126],"Proof-of-principle":[127],"that":[128],"marrow":[129],"administered":[131],"locally":[132],"engraft":[134],"give":[136,155],"rise":[137],"to":[138,154,176],"specialized":[139],"epithelial":[140],"has":[142],"been":[143],"given,":[144],"but":[145],"efficiency":[147],"conversion":[150],"too":[152],"limited":[153],"therapeutic":[157],"effect.":[158],"Besides":[159],"identification":[161],"mechanisms,":[164],"characterization/isolation":[166],"subpopulations":[171],"represents":[172],"major":[174],"challenge":[175],"improving":[177],"efficacy":[179],"transplantation":[181],"protocols":[182],"used":[183],"regenerative":[185],"medicine":[186]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}