{"id":"https://openalex.org/W2008807302","doi":"https://doi.org/10.1046/j.1525-1594.2003.07291.x","title":"Approach to Intradialytic Hypotension in Intensive Care Unit Patients with Acute Renal Failure","display_name":"Approach to Intradialytic Hypotension in Intensive Care Unit Patients with Acute Renal Failure","publication_year":2003,"publication_date":"2003-08-28","ids":{"openalex":"https://openalex.org/W2008807302","doi":"https://doi.org/10.1046/j.1525-1594.2003.07291.x","mag":"2008807302","pmid":"https://pubmed.ncbi.nlm.nih.gov/12940898"},"language":"en","primary_location":{"id":"doi:10.1046/j.1525-1594.2003.07291.x","doi":"https://doi.org/10.1046/j.1525-1594.2003.07291.x","is_oa":true,"landing_page_url":"https://doi.org/10.1046/j.1525-1594.2003.07291.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1046/j.1525-1594.2003.07291.x","source":{"id":"https://openalex.org/S40391745","display_name":"Artificial Organs","issn_l":"0160-564X","issn":["0160-564X","1525-1594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Artificial Organs","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1046/j.1525-1594.2003.07291.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087485954","display_name":"Mona D. Doshi","orcid":"https://orcid.org/0000-0003-2510-1951","observed_orcids":["https://orcid.org/0000-0003-2510-1951"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mona Doshi","raw_affiliation_strings":["Department of Medicine, University of Chicago, Chicago, IL, USA","\u2020Anesthesia and Critical Care Department and the Committee on Clinical Pharmacology, University of Chicago, Chicago, IL, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Chicago, Chicago, IL, USA","institution_ids":["https://openalex.org/I40347166"]},{"raw_affiliation_string":"\u2020Anesthesia and Critical Care Department and the Committee on Clinical Pharmacology, University of Chicago, Chicago, IL, U.S.A","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086691656","display_name":"Patrick T. Murray","orcid":"https://orcid.org/0000-0001-8516-1839","observed_orcids":["https://orcid.org/0000-0001-8516-1839"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Patrick T. Murray","raw_affiliation_strings":["*Department of Medicine, University of Chicago, Chicago, IL, U.S.A.; and \u2020Anesthesia and Critical Care Department and the Committee on Clinical Pharmacology, University of Chicago, Chicago, IL, U.S.A","*Department of Medicine, University of Chicago, Chicago, IL, U.S.A","\u2020Anesthesia and Critical Care Department and the Committee on Clinical Pharmacology, University of Chicago, Chicago, IL, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Department of Medicine, University of Chicago, Chicago, IL, U.S.A.; and \u2020Anesthesia and Critical Care Department and the Committee on Clinical Pharmacology, University of Chicago, Chicago, IL, U.S.A","institution_ids":["https://openalex.org/I40347166"]},{"raw_affiliation_string":"*Department of Medicine, University of Chicago, Chicago, IL, U.S.A","institution_ids":["https://openalex.org/I40347166"]},{"raw_affiliation_string":"\u2020Anesthesia and Critical Care Department and the Committee on Clinical Pharmacology, University of Chicago, Chicago, IL, U.S.A","institution_ids":["https://openalex.org/I40347166"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5086691656"],"corresponding_institution_ids":["https://openalex.org/I40347166"],"apc_list":{"value":3990,"currency":"USD","value_usd":3990},"apc_paid":null,"fwci":0.1162,"has_fulltext":true,"cited_by_count":42,"citation_normalized_percentile":{"value":0.1409396,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"27","issue":"9","first_page":"772","last_page":"780"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intradialytic-hypotension","display_name":"intradialytic hypotension","score":1.0},{"id":"https://openalex.org/keywords/acute-kidney-injury","display_name":"acute kidney injury","score":0.9810000061988831},{"id":"https://openalex.org/keywords/intensive-care-unit-patients","display_name":"intensive care unit patients","score":0.7699999809265137},{"id":"https://openalex.org/keywords/hemodialysis","display_name":"hemodialysis","score":0.7390000224113464},{"id":"https://openalex.org/keywords/renal-replacement-therapy","display_name":"renal replacement therapy","score":0.8650000095367432},{"id":"https://openalex.org/keywords/fluid-removal","display_name":"fluid removal","score":0.7160000205039978},{"id":"https://openalex.org/keywords/cardiac-dysfunction","display_name":"cardiac dysfunction","score":0.6890000104904175},{"id":"https://openalex.org/keywords/hypovolemia","display_name":"hypovolemia","score":0.7680000066757202},{"id":"https://openalex.org/keywords/vasodilation","display_name":"vasodilation","score":0.8420000076293945},{"id":"https://openalex.org/keywords/vascular-contractility","display_name":"vascular contractility","score":0.8399999737739563},{"id":"https://openalex.org/keywords/critically-ill-patients","display_name":"critically ill patients","score":0.6740000247955322}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8592249155044556},{"id":"https://openalex.org/C2778063415","wikidata":"https://www.wikidata.org/wiki/Q391744","display_name":"Hemodialysis","level":2,"score":0.733062744140625},{"id":"https://openalex.org/C2779978075","wikidata":"https://www.wikidata.org/wiki/Q202301","display_name":"Dialysis","level":2,"score":0.7239828705787659},{"id":"https://openalex.org/C2779541074","wikidata":"https://www.wikidata.org/wiki/Q185643","display_name":"Renal replacement therapy","level":2,"score":0.6091440916061401},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.5207735896110535},{"id":"https://openalex.org/C2776376669","wikidata":"https://www.wikidata.org/wiki/Q5094647","display_name":"Intensive care unit","level":2,"score":0.5141072869300842},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4711873531341553},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4510200023651123},{"id":"https://openalex.org/C139940330","wikidata":"https://www.wikidata.org/wiki/Q596579","display_name":"Cardiac output","level":3,"score":0.4300300180912018},{"id":"https://openalex.org/C2780472472","wikidata":"https://www.wikidata.org/wiki/Q424337","display_name":"Acute kidney injury","level":2,"score":0.42946815490722656},{"id":"https://openalex.org/C2776850375","wikidata":"https://www.wikidata.org/wiki/Q2477062","display_name":"Cardiogenic shock","level":3,"score":0.4184392988681793},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.41107994318008423},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4071105718612671},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.07205009460449219}],"mesh":[{"descriptor_ui":"D003422","descriptor_name":"Critical Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006435","descriptor_name":"Renal Dialysis","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007022","descriptor_name":"Hypotension","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D007022","descriptor_name":"Hypotension","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1046/j.1525-1594.2003.07291.x","doi":"https://doi.org/10.1046/j.1525-1594.2003.07291.x","is_oa":true,"landing_page_url":"https://doi.org/10.1046/j.1525-1594.2003.07291.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1046/j.1525-1594.2003.07291.x","source":{"id":"https://openalex.org/S40391745","display_name":"Artificial Organs","issn_l":"0160-564X","issn":["0160-564X","1525-1594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Artificial Organs","raw_type":"journal-article"},{"id":"pmid:12940898","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12940898","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Artificial organs","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1046/j.1525-1594.2003.07291.x","doi":"https://doi.org/10.1046/j.1525-1594.2003.07291.x","is_oa":true,"landing_page_url":"https://doi.org/10.1046/j.1525-1594.2003.07291.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1046/j.1525-1594.2003.07291.x","source":{"id":"https://openalex.org/S40391745","display_name":"Artificial Organs","issn_l":"0160-564X","issn":["0160-564X","1525-1594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Artificial Organs","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8399999737739563}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4472523856","display_name":"Effects of Vasoactive Drugs on Perfusion in Septic Shock","funder_award_id":"K23GM000713","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G6169209999","display_name":null,"funder_award_id":"1K23GM00713-01A1","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2008807302.pdf","grobid_xml":"https://content.openalex.org/works/W2008807302.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W1825602445","https://openalex.org/W1965637914","https://openalex.org/W1966608261","https://openalex.org/W1971226409","https://openalex.org/W1981533678","https://openalex.org/W1985896094","https://openalex.org/W1986347387","https://openalex.org/W1992311120","https://openalex.org/W1994413539","https://openalex.org/W1994868010","https://openalex.org/W1997278766","https://openalex.org/W1997981274","https://openalex.org/W2003865960","https://openalex.org/W2004095374","https://openalex.org/W2006075878","https://openalex.org/W2008501189","https://openalex.org/W2012978651","https://openalex.org/W2022608799","https://openalex.org/W2024074892","https://openalex.org/W2025570414","https://openalex.org/W2028429844","https://openalex.org/W2039354600","https://openalex.org/W2042268246","https://openalex.org/W2043937291","https://openalex.org/W2045886286","https://openalex.org/W2049693846","https://openalex.org/W2051200254","https://openalex.org/W2053297027","https://openalex.org/W2060357576","https://openalex.org/W2062054105","https://openalex.org/W2065589098","https://openalex.org/W2067176790","https://openalex.org/W2079526141","https://openalex.org/W2082552047","https://openalex.org/W2092576934","https://openalex.org/W2095536287","https://openalex.org/W2096295887","https://openalex.org/W2107668335","https://openalex.org/W2144408525","https://openalex.org/W2148973700","https://openalex.org/W2156856199","https://openalex.org/W2158830464","https://openalex.org/W2160691650","https://openalex.org/W2171076611","https://openalex.org/W2291970350","https://openalex.org/W2310851671","https://openalex.org/W2443188319","https://openalex.org/W2550507245","https://openalex.org/W3026502384"],"related_works":["https://openalex.org/W2384161729","https://openalex.org/W4242736398","https://openalex.org/W3040806809","https://openalex.org/W2031447323","https://openalex.org/W2727347476","https://openalex.org/W2142856016","https://openalex.org/W3193736576","https://openalex.org/W4403834344","https://openalex.org/W6986875365","https://openalex.org/W1998806990"],"abstract_inverted_index":{"The":[0],"increasing":[1],"prevalence":[2],"of":[3,12,18,30,37,53,99],"acute":[4],"renal":[5,38],"failure":[6],"(ARF)":[7],"patients":[8],"with":[9],"hemodynamic":[10,80],"intolerance":[11],"intermittent":[13],"hemodialysis":[14],"(HD),":[15],"generally":[16],"because":[17],"septic":[19],"vasoparesis":[20],"or":[21],"severe":[22],"cardiac":[23,117],"dysfunction,":[24],"has":[25],"led":[26],"to":[27,33,94],"the":[28,35,51,61,95],"development":[29],"several":[31],"strategies":[32],"improve":[34],"delivery":[36],"replacement":[39],"therapy":[40],"(RRT)":[41],"in":[42,101],"ARF":[43,104],"patients.":[44],"Intradialytic":[45],"hypotension":[46],"(IDH)":[47],"is":[48],"caused":[49,82],"by":[50,83,113],"interaction":[52],"dialysis-dependent":[54],"and":[55,68,75,87,97,110,119],"dialysis-independent":[56],"factors.":[57],"Dialysis-dependent":[58],"factors":[59,78],"include":[60,79],"prescriptions":[62],"for":[63],"fluid":[64,115],"removal,":[65,67,116],"solute":[66],"dialysate":[69],"components":[70],"such":[71],"as":[72],"sodium,":[73],"buffer,":[74],"calcium.":[76],"Dialysis-independent":[77],"compromise":[81],"hypovolemic,":[84,108],"cardiogenic,":[85,109],"vasodilatory,":[86],"mixed":[88],"mechanisms.":[89],"We":[90],"propose":[91],"an":[92],"approach":[93],"prevention":[96],"management":[98],"IDH":[100],"critically":[102],"ill":[103],"patients,":[105],"which":[106],"minimizes":[107],"vasodilatory":[111],"insults":[112],"optimizing":[114],"function,":[118],"vascular":[120],"contractility.":[121]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":5},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":7}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}