{"id":"https://openalex.org/W2008770488","doi":"https://doi.org/10.1006/dbio.2002.0869","title":"Runnin' with the Dvl: Proteins That Associate with Dsh/Dvl and Their Significance to Wnt Signal Transduction","display_name":"Runnin' with the Dvl: Proteins That Associate with Dsh/Dvl and Their Significance to Wnt Signal Transduction","publication_year":2003,"publication_date":"2003-01-01","ids":{"openalex":"https://openalex.org/W2008770488","doi":"https://doi.org/10.1006/dbio.2002.0869","mag":"2008770488","pmid":"https://pubmed.ncbi.nlm.nih.gov/12490194"},"language":"en","primary_location":{"id":"doi:10.1006/dbio.2002.0869","doi":"https://doi.org/10.1006/dbio.2002.0869","is_oa":true,"landing_page_url":"https://doi.org/10.1006/dbio.2002.0869","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0012160602908699/pdf","source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.sciencedirect.com/science/article/pii/S0012160602908699/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027262882","display_name":"Keith A. Wharton","orcid":"https://orcid.org/0000-0003-0374-1114","observed_orcids":["https://orcid.org/0000-0003-0374-1114"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Keith A Wharton","raw_affiliation_strings":["Department of Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas, 75390-9072, USA. Keith.Wharton@UTSouthwestern.edu","Department of Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas, 75390-9072, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas, 75390-9072, USA. Keith.Wharton@UTSouthwestern.edu","institution_ids":["https://openalex.org/I867280407"]},{"raw_affiliation_string":"Department of Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas, 75390-9072, USA","institution_ids":["https://openalex.org/I867280407"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5027262882"],"corresponding_institution_ids":["https://openalex.org/I867280407"],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":2.8072,"has_fulltext":true,"cited_by_count":313,"citation_normalized_percentile":{"value":0.93681015,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"253","issue":"1","first_page":"1","last_page":"17"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12009","display_name":"Hedgehog Signaling Pathway Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wnt-signaling","display_name":"Wnt signaling","score":0.828000009059906},{"id":"https://openalex.org/keywords/dishevelled","display_name":"Dishevelled","score":0.8809999823570251},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"signal transduction","score":0.7360000014305115},{"id":"https://openalex.org/keywords/signaling-complexes","display_name":"signaling complexes","score":0.6579999923706055},{"id":"https://openalex.org/keywords/feedback-regulation","display_name":"feedback regulation","score":0.746999979019165},{"id":"https://openalex.org/keywords/signal-amplification","display_name":"signal amplification","score":0.7089999914169312},{"id":"https://openalex.org/keywords/cell-fate-determination","display_name":"cell fate determination","score":0.7229999899864197},{"id":"https://openalex.org/keywords/stem-cell-maintenance","display_name":"stem cell maintenance","score":0.7770000100135803},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.5590000152587891},{"id":"https://openalex.org/keywords/osteoporosis","display_name":"osteoporosis","score":0.843999981880188},{"id":"https://openalex.org/keywords/calcium-signaling","display_name":"calcium signaling","score":0.5740000009536743}],"concepts":[{"id":"https://openalex.org/C137620995","wikidata":"https://www.wikidata.org/wiki/Q155769","display_name":"Wnt signaling pathway","level":3,"score":0.9292601943016052},{"id":"https://openalex.org/C2775928862","wikidata":"https://www.wikidata.org/wiki/Q5282208","display_name":"Dishevelled","level":5,"score":0.8314628005027771},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8009718656539917},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6236011981964111},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.5838209986686707},{"id":"https://openalex.org/C163952510","wikidata":"https://www.wikidata.org/wiki/Q5058196","display_name":"Cell fate determination","level":4,"score":0.5788552761077881},{"id":"https://openalex.org/C51785407","wikidata":"https://www.wikidata.org/wiki/Q2627568","display_name":"Effector","level":2,"score":0.5023448467254639},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.4282681941986084},{"id":"https://openalex.org/C49353375","wikidata":"https://www.wikidata.org/wiki/Q189100","display_name":"Cell polarity","level":3,"score":0.4255502223968506},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.38459745049476624},{"id":"https://openalex.org/C107300179","wikidata":"https://www.wikidata.org/wiki/Q41797887","display_name":"Frizzled","level":4,"score":0.3087519407272339},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2814069390296936},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13974541425704956},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.13785776495933533},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000072261","descriptor_name":"Dishevelled Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010750","descriptor_name":"Phosphoproteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010750","descriptor_name":"Phosphoproteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D029961","descriptor_name":"Zebrafish Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D048868","descriptor_name":"Adaptor Proteins, Signal Transducing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051153","descriptor_name":"Wnt Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1006/dbio.2002.0869","doi":"https://doi.org/10.1006/dbio.2002.0869","is_oa":true,"landing_page_url":"https://doi.org/10.1006/dbio.2002.0869","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0012160602908699/pdf","source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},{"id":"pmid:12490194","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12490194","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental biology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1006/dbio.2002.0869","doi":"https://doi.org/10.1006/dbio.2002.0869","is_oa":true,"landing_page_url":"https://doi.org/10.1006/dbio.2002.0869","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0012160602908699/pdf","source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2008770488.pdf","grobid_xml":"https://content.openalex.org/works/W2008770488.grobid-xml"},"referenced_works_count":189,"referenced_works":["https://openalex.org/W86737493","https://openalex.org/W124539320","https://openalex.org/W1485377536","https://openalex.org/W1487123743","https://openalex.org/W1494249446","https://openalex.org/W1504655784","https://openalex.org/W1512355975","https://openalex.org/W1533171633","https://openalex.org/W1535438232","https://openalex.org/W1544046482","https://openalex.org/W1545602072","https://openalex.org/W1552824037","https://openalex.org/W1557541313","https://openalex.org/W1573866353","https://openalex.org/W1598713761","https://openalex.org/W1611720630","https://openalex.org/W1635607892","https://openalex.org/W1664587663","https://openalex.org/W1867818836","https://openalex.org/W1901013657","https://openalex.org/W1911201077","https://openalex.org/W1953109900","https://openalex.org/W1964391716","https://openalex.org/W1964739066","https://openalex.org/W1965927965","https://openalex.org/W1966619635","https://openalex.org/W1967137553","https://openalex.org/W1968137237","https://openalex.org/W1968717680","https://openalex.org/W1972352539","https://openalex.org/W1973466091","https://openalex.org/W1973844181","https://openalex.org/W1974313494","https://openalex.org/W1974712344","https://openalex.org/W1975516052","https://openalex.org/W1978047924","https://openalex.org/W1979825058","https://openalex.org/W1980719358","https://openalex.org/W1986368793","https://openalex.org/W1987704449","https://openalex.org/W1988658871","https://openalex.org/W1988846042","https://openalex.org/W1991461487","https://openalex.org/W1991756459","https://openalex.org/W1996301541","https://openalex.org/W1996788021","https://openalex.org/W2000352591","https://openalex.org/W2001054344","https://openalex.org/W2001355136","https://openalex.org/W2001856716","https://openalex.org/W2003286575","https://openalex.org/W2005865365","https://openalex.org/W2006671195","https://openalex.org/W2008169769","https://openalex.org/W2010892881","https://openalex.org/W2012031348","https://openalex.org/W2013251746","https://openalex.org/W2013460988","https://openalex.org/W2013541197","https://openalex.org/W2014460650","https://openalex.org/W2016488651","https://openalex.org/W2017668082","https://openalex.org/W2018130911","https://openalex.org/W2021934355","https://openalex.org/W2022798578","https://openalex.org/W2023273217","https://openalex.org/W2024451865","https://openalex.org/W2026112588","https://openalex.org/W2027286743","https://openalex.org/W2027356109","https://openalex.org/W2030491643","https://openalex.org/W2035140381","https://openalex.org/W2036864436","https://openalex.org/W2038119196","https://openalex.org/W2039248606","https://openalex.org/W2039661491","https://openalex.org/W2040942754","https://openalex.org/W2042541560","https://openalex.org/W2044764655","https://openalex.org/W2046770463","https://openalex.org/W2046952556","https://openalex.org/W2048451929","https://openalex.org/W2051032088","https://openalex.org/W2055557491","https://openalex.org/W2055654424","https://openalex.org/W2057208748","https://openalex.org/W2059908281","https://openalex.org/W2059954649","https://openalex.org/W2061170173","https://openalex.org/W2061600278","https://openalex.org/W2065989745","https://openalex.org/W2067271873","https://openalex.org/W2069088674","https://openalex.org/W2070548790","https://openalex.org/W2071915231","https://openalex.org/W2072392892","https://openalex.org/W2075319861","https://openalex.org/W2075460910","https://openalex.org/W2075983586","https://openalex.org/W2079140208","https://openalex.org/W2080661409","https://openalex.org/W2081985759","https://openalex.org/W2082120029","https://openalex.org/W2082387343","https://openalex.org/W2082978552","https://openalex.org/W2084060837","https://openalex.org/W2087993696","https://openalex.org/W2088365719","https://openalex.org/W2088429363","https://openalex.org/W2088942336","https://openalex.org/W2090977067","https://openalex.org/W2091154399","https://openalex.org/W2091605975","https://openalex.org/W2092117239","https://openalex.org/W2092282322","https://openalex.org/W2092977027","https://openalex.org/W2097098623","https://openalex.org/W2098024635","https://openalex.org/W2098357545","https://openalex.org/W2098802640","https://openalex.org/W2102512027","https://openalex.org/W2103110972","https://openalex.org/W2105277147","https://openalex.org/W2105571987","https://openalex.org/W2106682677","https://openalex.org/W2110932416","https://openalex.org/W2112178369","https://openalex.org/W2114511731","https://openalex.org/W2114978834","https://openalex.org/W2116011728","https://openalex.org/W2117330555","https://openalex.org/W2118344768","https://openalex.org/W2118729125","https://openalex.org/W2120657906","https://openalex.org/W2120983879","https://openalex.org/W2121685290","https://openalex.org/W2123269248","https://openalex.org/W2124008135","https://openalex.org/W2124772662","https://openalex.org/W2125499046","https://openalex.org/W2125545718","https://openalex.org/W2127251425","https://openalex.org/W2129096696","https://openalex.org/W2130617167","https://openalex.org/W2132475598","https://openalex.org/W2133172561","https://openalex.org/W2133578310","https://openalex.org/W2133769699","https://openalex.org/W2134485689","https://openalex.org/W2135955567","https://openalex.org/W2139392120","https://openalex.org/W2139936955","https://openalex.org/W2146877009","https://openalex.org/W2146916662","https://openalex.org/W2148074532","https://openalex.org/W2148450224","https://openalex.org/W2148893919","https://openalex.org/W2149429346","https://openalex.org/W2149871164","https://openalex.org/W2150589615","https://openalex.org/W2151558240","https://openalex.org/W2151582261","https://openalex.org/W2152769008","https://openalex.org/W2153182714","https://openalex.org/W2153447703","https://openalex.org/W2157452165","https://openalex.org/W2158910153","https://openalex.org/W2159655851","https://openalex.org/W2164418509","https://openalex.org/W2164692746","https://openalex.org/W2168820955","https://openalex.org/W2169478707","https://openalex.org/W2170899721","https://openalex.org/W2181885838","https://openalex.org/W2183101660","https://openalex.org/W2185643875","https://openalex.org/W2344098985","https://openalex.org/W2412108038","https://openalex.org/W2472955934","https://openalex.org/W4250170407","https://openalex.org/W4299144360","https://openalex.org/W4321429223","https://openalex.org/W4365787717","https://openalex.org/W6650744442","https://openalex.org/W6678299533","https://openalex.org/W6704684186","https://openalex.org/W7075576566","https://openalex.org/W7095415099","https://openalex.org/W7097257549"],"related_works":["https://openalex.org/W2229568458","https://openalex.org/W2005440429","https://openalex.org/W2035154210","https://openalex.org/W1523822300","https://openalex.org/W2791332544","https://openalex.org/W4404244746","https://openalex.org/W2092977027","https://openalex.org/W1982278818","https://openalex.org/W2084060837","https://openalex.org/W2100721730"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":13},{"year":2012,"cited_by_count":19}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}