{"id":"https://openalex.org/W2008707569","doi":"https://doi.org/10.1073/pnas.1009566107","title":"Most harmful algal bloom species are vitamin B 1 and B 12 auxotrophs","display_name":"Most harmful algal bloom species are vitamin B 1 and B 12 auxotrophs","publication_year":2010,"publication_date":"2010-11-10","ids":{"openalex":"https://openalex.org/W2008707569","doi":"https://doi.org/10.1073/pnas.1009566107","mag":"2008707569","pmid":"https://pubmed.ncbi.nlm.nih.gov/21068377","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2996436"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.1009566107","doi":"https://doi.org/10.1073/pnas.1009566107","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.1009566107","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2996436/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008429967","display_name":"Ying Zhong Tang","orcid":"https://orcid.org/0000-0003-0446-3128","observed_orcids":["https://orcid.org/0000-0003-0446-3128"]},"institutions":[{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ying Zhong Tang","raw_affiliation_strings":["School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY 11794-5000","School of Marine and Atmospheric Sciences; Stony Brook University; Stony Brook; NY; 11794-5000; USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY 11794-5000","institution_ids":["https://openalex.org/I59553526"]},{"raw_affiliation_string":"School of Marine and Atmospheric Sciences; Stony Brook University; Stony Brook; NY; 11794-5000; USA","institution_ids":["https://openalex.org/I59553526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051256932","display_name":"Florian Koch","orcid":"https://orcid.org/0000-0001-7107-4160","observed_orcids":["https://orcid.org/0000-0001-7107-4160"]},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]},{"id":"https://openalex.org/I1331384533","display_name":"University of Hawaii System","ror":"https://ror.org/03tzaeb71","country_code":"US","type":"education","lineage":["https://openalex.org/I1331384533"]},{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Florian Koch","raw_affiliation_strings":["School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY 11794-5000","University of Hawaii, Honolulu, HI,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY 11794-5000","institution_ids":["https://openalex.org/I59553526"]},{"raw_affiliation_string":"University of Hawaii, Honolulu, HI,","institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1331384533"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082611620","display_name":"Christopher J. Gobler","orcid":"https://orcid.org/0000-0002-7576-8079","observed_orcids":["https://orcid.org/0000-0002-7576-8079"]},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]},{"id":"https://openalex.org/I1331384533","display_name":"University of Hawaii System","ror":"https://ror.org/03tzaeb71","country_code":"US","type":"education","lineage":["https://openalex.org/I1331384533"]},{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Christopher J. Gobler","raw_affiliation_strings":["School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY 11794-5000","University of Hawaii, Honolulu, HI,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY 11794-5000","institution_ids":["https://openalex.org/I59553526"]},{"raw_affiliation_string":"University of Hawaii, Honolulu, HI,","institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1331384533"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5082611620"],"corresponding_institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1331384533","https://openalex.org/I59553526"],"apc_list":null,"apc_paid":null,"fwci":7.319,"has_fulltext":false,"cited_by_count":286,"citation_normalized_percentile":{"value":0.98347646,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"107","issue":"48","first_page":"20756","last_page":"20761"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10236","display_name":"Aquatic Ecosystems and Phytoplankton Dynamics","score":0.5083000063896179,"subfield":{"id":"https://openalex.org/subfields/2304","display_name":"Environmental Chemistry"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10236","display_name":"Aquatic Ecosystems and Phytoplankton Dynamics","score":0.5083000063896179,"subfield":{"id":"https://openalex.org/subfields/2304","display_name":"Environmental Chemistry"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10032","display_name":"Marine Plankton and Biogeochemistry","score":0.4733999967575073,"subfield":{"id":"https://openalex.org/subfields/1910","display_name":"Oceanography"},"field":{"id":"https://openalex.org/fields/19","display_name":"Earth and Planetary Sciences"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11985","display_name":"Marine Toxins and Detection Methods","score":0.012000000104308128,"subfield":{"id":"https://openalex.org/subfields/2304","display_name":"Environmental Chemistry"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/harmful-algal-blooms","display_name":"harmful algal blooms","score":1.0},{"id":"https://openalex.org/keywords/vitamin-b12","display_name":"vitamin B12","score":0.8029999732971191},{"id":"https://openalex.org/keywords/thiamine","display_name":"thiamine","score":0.9129999876022339},{"id":"https://openalex.org/keywords/biotin","display_name":"biotin","score":0.9710000157356262},{"id":"https://openalex.org/keywords/dinoflagellates","display_name":"dinoflagellates","score":0.9399999976158142},{"id":"https://openalex.org/keywords/micronutrient-requirements","display_name":"micronutrient requirements","score":0.7870000004768372},{"id":"https://openalex.org/keywords/eutrophication","display_name":"eutrophication","score":0.9070000052452087},{"id":"https://openalex.org/keywords/half-saturation-constant","display_name":"half-saturation constant","score":0.871999979019165}],"concepts":[{"id":"https://openalex.org/C20950039","wikidata":"https://www.wikidata.org/wiki/Q578111","display_name":"Auxotrophy","level":4,"score":0.7254676222801208},{"id":"https://openalex.org/C120305227","wikidata":"https://www.wikidata.org/wiki/Q326139","display_name":"Algal bloom","level":4,"score":0.6285597085952759},{"id":"https://openalex.org/C2992865179","wikidata":"https://www.wikidata.org/wiki/Q183206","display_name":"Vitamin b","level":3,"score":0.5194041728973389},{"id":"https://openalex.org/C155567681","wikidata":"https://www.wikidata.org/wiki/Q2987425","display_name":"Bloom","level":2,"score":0.5050702691078186},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.45273393392562866},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.36789634823799133},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.35242897272109985},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.33338773250579834},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.3112935423851013},{"id":"https://openalex.org/C142796444","wikidata":"https://www.wikidata.org/wiki/Q181394","display_name":"Nutrient","level":2,"score":0.1725858449935913},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16434597969055176},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15175828337669373},{"id":"https://openalex.org/C2780892065","wikidata":"https://www.wikidata.org/wiki/Q184755","display_name":"Phytoplankton","level":3,"score":0.12736603617668152},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11135628819465637},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013831","descriptor_name":"Thiamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014805","descriptor_name":"Vitamin B 12","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D057097","descriptor_name":"Harmful Algal Bloom","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D058086","descriptor_name":"Microalgae","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D058086","descriptor_name":"Microalgae","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D058086","descriptor_name":"Microalgae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1073/pnas.1009566107","doi":"https://doi.org/10.1073/pnas.1009566107","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.1009566107","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmid:21068377","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21068377","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2996436","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2996436/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2996436","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2996436/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G5199779353","display_name":"Regulation of Dinoflagellate Bloom Dynamics by Vitamins and Micronutrients","funder_award_id":"0623432","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320320698","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49"},{"id":"https://openalex.org/F4320322292","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62"},{"id":"https://openalex.org/F4320331904","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33"},{"id":"https://openalex.org/F4320334596","display_name":"Fisheries and Oceans Canada","ror":"https://ror.org/02qa1x782"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":61,"referenced_works":["https://openalex.org/W170475839","https://openalex.org/W235027445","https://openalex.org/W1480513510","https://openalex.org/W1963605857","https://openalex.org/W1965399445","https://openalex.org/W1968539356","https://openalex.org/W1969311963","https://openalex.org/W1973438833","https://openalex.org/W1980733427","https://openalex.org/W1981787480","https://openalex.org/W1997748251","https://openalex.org/W2000706057","https://openalex.org/W2003486798","https://openalex.org/W2012414518","https://openalex.org/W2012612785","https://openalex.org/W2018805081","https://openalex.org/W2020349936","https://openalex.org/W2021238147","https://openalex.org/W2027355960","https://openalex.org/W2034509806","https://openalex.org/W2037363735","https://openalex.org/W2046693257","https://openalex.org/W2047180495","https://openalex.org/W2050386030","https://openalex.org/W2052415792","https://openalex.org/W2052501806","https://openalex.org/W2067863532","https://openalex.org/W2068170620","https://openalex.org/W2070842858","https://openalex.org/W2071442724","https://openalex.org/W2080996038","https://openalex.org/W2088759037","https://openalex.org/W2089891379","https://openalex.org/W2094961712","https://openalex.org/W2095489410","https://openalex.org/W2096593525","https://openalex.org/W2104297980","https://openalex.org/W2110533085","https://openalex.org/W2115809742","https://openalex.org/W2119846653","https://openalex.org/W2125951559","https://openalex.org/W2138188700","https://openalex.org/W2140586706","https://openalex.org/W2145112903","https://openalex.org/W2146165981","https://openalex.org/W2159766367","https://openalex.org/W2160201546","https://openalex.org/W2160226562","https://openalex.org/W2166873045","https://openalex.org/W2167598246","https://openalex.org/W2318698633","https://openalex.org/W2796323961","https://openalex.org/W2899862539","https://openalex.org/W2912130211","https://openalex.org/W3133519372","https://openalex.org/W3157908117","https://openalex.org/W4246891081","https://openalex.org/W4252745119","https://openalex.org/W4255391112","https://openalex.org/W6704283484","https://openalex.org/W6816581236"],"related_works":["https://openalex.org/W7221499968","https://openalex.org/W2076860188","https://openalex.org/W7116836207","https://openalex.org/W2094961712","https://openalex.org/W6977126527","https://openalex.org/W2169184226","https://openalex.org/W2329123592","https://openalex.org/W2090157291","https://openalex.org/W2110040124","https://openalex.org/W2734166345"],"abstract_inverted_index":{"Eutrophication":[0],"can":[1],"play":[2],"a":[3,27,69,79],"central":[4],"role":[5,206],"in":[6,54,171,179,192,209],"promoting":[7],"harmful":[8,116],"algal":[9,30],"blooms":[10],"(HABs),":[11],"and":[12,65,78,95,128,154,165],"therefore":[13],"many":[14],"HAB":[15,82,103,150,182],"studies":[16],"to":[17,167,194],"date":[18],"have":[19,67],"focused":[20],"on":[21],"macronutrients":[22],"(N,":[23],"P,":[24],"Si).":[25],"Although":[26],"majority":[28],"of":[29,44,63,73,81,98,101,115,123,130,148,190,198,207,213],"species":[31,83,104,112,125,132,151],"require":[32],"exogenous":[33],"B":[34,39,49],"vitamins":[35,50,64,176,185,191],"(i.e.,":[36],"auxotrophic":[37],"for":[38,142,152,162,175,184],"vitamins),":[40],"the":[41,88,91,139,202,211],"possible":[42],"importance":[43],"organic":[45],"micronutrients":[46],"such":[47],"as":[48],"(B(1),":[51],"B(7),":[52,94,134],"B(12))":[53],"regulating":[55,210],"HABs":[56],"has":[57],"rarely":[58],"been":[59],"considered.":[60],"Prior":[61],"investigations":[62],"algae":[66,117],"examined":[68],"relatively":[70],"small":[71],"number":[72],"dinoflagellates":[74],"(n":[75,84],"=":[76,85],"26)":[77],"paucity":[80],"4).":[86],"In":[87],"present":[89],"study,":[90],"vitamin":[92,120,168],"B(1),":[93,127],"B(12)":[96,155],"requirements":[97],"41":[99],"strains":[100],"27":[102,124,131],"(19":[105],"dinoflagellates)":[106],"were":[107,156],"investigated.":[108],"All":[109],"but":[110],"one":[111],"(two":[113],"strains)":[114],"surveyed":[118],"required":[119,126,133],"B(12),":[121],"20":[122],"10":[129],"all":[135],"proportions":[136],"higher":[137,157],"than":[138,158],"previously":[140,160],"reported":[141,161,170],"non-HAB":[143],"species.":[144],"Half-saturation":[145],"(K(s))":[146],"constants":[147],"several":[149],"B(1)":[153],"those":[159],"other":[163],"phytoplankton":[164],"similar":[166],"concentrations":[169],"estuaries.":[172],"Cellular":[173],"quotas":[174],"suggest":[177],"that,":[178],"some":[180],"cases,":[181],"demands":[183],"may":[186],"exhaust":[187],"standing":[188],"stocks":[189],"hours":[193],"days.":[195],"The":[196],"sum":[197],"these":[199],"findings":[200],"demonstrates":[201],"potentially":[203],"significant":[204],"ecological":[205],"B-vitamins":[208],"dynamics":[212],"HABs.":[214]},"counts_by_year":[{"year":2026,"cited_by_count":22},{"year":2025,"cited_by_count":21},{"year":2024,"cited_by_count":25},{"year":2023,"cited_by_count":26},{"year":2022,"cited_by_count":27},{"year":2021,"cited_by_count":17},{"year":2020,"cited_by_count":25},{"year":2019,"cited_by_count":23},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":18},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":14},{"year":2014,"cited_by_count":14},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":14}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}