{"id":"https://openalex.org/W2008586010","doi":"https://doi.org/10.1016/j.jns.2005.03.004","title":"Steroid hormones in multiple sclerosis","display_name":"Steroid hormones in multiple sclerosis","publication_year":2005,"publication_date":"2005-05-06","ids":{"openalex":"https://openalex.org/W2008586010","doi":"https://doi.org/10.1016/j.jns.2005.03.004","mag":"2008586010","pmid":"https://pubmed.ncbi.nlm.nih.gov/15878598"},"language":"en","primary_location":{"id":"doi:10.1016/j.jns.2005.03.004","doi":"https://doi.org/10.1016/j.jns.2005.03.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jns.2005.03.004","pdf_url":null,"source":{"id":"https://openalex.org/S169054600","display_name":"Journal of the Neurological Sciences","issn_l":"0022-510X","issn":["0022-510X","1878-5883"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Neurological Sciences","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103541336","display_name":"Martine El\u2010Etr","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Martine El-Etr","raw_affiliation_strings":["INSERM, U\u2010488, Le Kremlin, Bic\u00eatre, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM, U\u2010488, Le Kremlin, Bic\u00eatre, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025662371","display_name":"Sandra Vukusic","orcid":"https://orcid.org/0000-0001-7337-7122","observed_orcids":["https://orcid.org/0000-0001-7337-7122"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210105768","display_name":"H\u00f4pital Pierre Wertheimer","ror":"https://ror.org/01q046q46","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210100596","https://openalex.org/I4210105768"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sandra Vukusic","raw_affiliation_strings":["Service de Neurologie A, INSERM U 433, and EDMUS Coordinating Centre, H\u00f4pital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 LYON-Bron Cedex 03, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Neurologie A, INSERM U 433, and EDMUS Coordinating Centre, H\u00f4pital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 LYON-Bron Cedex 03, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210105768"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036619456","display_name":"Laurence Gignoux","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210105768","display_name":"H\u00f4pital Pierre Wertheimer","ror":"https://ror.org/01q046q46","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210100596","https://openalex.org/I4210105768"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Laurence Gignoux","raw_affiliation_strings":["Service de Neurologie A, INSERM U 433, and EDMUS Coordinating Centre, H\u00f4pital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 LYON-Bron Cedex 03, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Neurologie A, INSERM U 433, and EDMUS Coordinating Centre, H\u00f4pital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 LYON-Bron Cedex 03, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210105768"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101518202","display_name":"Fran\u00e7oise Durand\u2010Dubief","orcid":"https://orcid.org/0000-0002-2860-1700","observed_orcids":["https://orcid.org/0000-0002-2860-1700"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210105768","display_name":"H\u00f4pital Pierre Wertheimer","ror":"https://ror.org/01q046q46","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210100596","https://openalex.org/I4210105768"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fran\u00e7oise Durand-Dubief","raw_affiliation_strings":["Service de Neurologie A, INSERM U 433, and EDMUS Coordinating Centre, H\u00f4pital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 LYON-Bron Cedex 03, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Neurologie A, INSERM U 433, and EDMUS Coordinating Centre, H\u00f4pital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 LYON-Bron Cedex 03, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210105768"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030284253","display_name":"Iuliana Achiti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210105768","display_name":"H\u00f4pital Pierre Wertheimer","ror":"https://ror.org/01q046q46","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210100596","https://openalex.org/I4210105768"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Iuliana Achiti","raw_affiliation_strings":["Service de Neurologie A, INSERM U 433, and EDMUS Coordinating Centre, H\u00f4pital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 LYON-Bron Cedex 03, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Neurologie A, INSERM U 433, and EDMUS Coordinating Centre, H\u00f4pital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 LYON-Bron Cedex 03, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210105768"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053560361","display_name":"E.E. Baulieu","orcid":"https://orcid.org/0000-0002-2532-5085","observed_orcids":["https://orcid.org/0000-0002-2532-5085"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Etienne Emile Baulieu","raw_affiliation_strings":["INSERM, U\u2010488, Le Kremlin, Bic\u00eatre, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM, U\u2010488, Le Kremlin, Bic\u00eatre, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108444138","display_name":"Christian Confavreux","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210105768","display_name":"H\u00f4pital Pierre Wertheimer","ror":"https://ror.org/01q046q46","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210100596","https://openalex.org/I4210105768"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Christian Confavreux","raw_affiliation_strings":["Service de Neurologie A, INSERM U 433, and EDMUS Coordinating Centre, H\u00f4pital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 LYON-Bron Cedex 03, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Neurologie A, INSERM U 433, and EDMUS Coordinating Centre, H\u00f4pital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 LYON-Bron Cedex 03, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210105768"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3640,"currency":"USD","value_usd":3640},"apc_paid":null,"fwci":1.201,"has_fulltext":false,"cited_by_count":80,"citation_normalized_percentile":{"value":0.7306425,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"233","issue":"1-2","first_page":"49","last_page":"54"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-sclerosis","display_name":"multiple sclerosis","score":0.9649999737739563},{"id":"https://openalex.org/keywords/sex-steroids","display_name":"sex steroids","score":0.7400000095367432},{"id":"https://openalex.org/keywords/steroid-hormones","display_name":"steroid hormones","score":0.871999979019165},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.8190000057220459},{"id":"https://openalex.org/keywords/menstrual-cycle","display_name":"menstrual cycle","score":0.9670000076293945},{"id":"https://openalex.org/keywords/relapse-rate","display_name":"relapse rate","score":0.7960000038146973},{"id":"https://openalex.org/keywords/postpartum-relapse","display_name":"postpartum relapse","score":0.7900000214576721},{"id":"https://openalex.org/keywords/sex-differences-in-disease-susceptibility","display_name":"sex differences in disease susceptibility","score":0.6990000009536743},{"id":"https://openalex.org/keywords/experimental-autoimmune-encephalomyelitis","display_name":"experimental autoimmune encephalomyelitis","score":0.9380000233650208},{"id":"https://openalex.org/keywords/remyelination","display_name":"remyelination","score":0.9490000009536743},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.7919999957084656}],"concepts":[{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.8830878138542175},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.7569625377655029},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.6591924428939819},{"id":"https://openalex.org/C2777899865","wikidata":"https://www.wikidata.org/wiki/Q1634879","display_name":"Encephalomyelitis","level":3,"score":0.6198216676712036},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5857624411582947},{"id":"https://openalex.org/C2779058012","wikidata":"https://www.wikidata.org/wiki/Q83864","display_name":"Menstrual cycle","level":3,"score":0.5353788137435913},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.47822970151901245},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.4728562831878662},{"id":"https://openalex.org/C2779938979","wikidata":"https://www.wikidata.org/wiki/Q422812","display_name":"Sex steroid","level":4,"score":0.42878013849258423},{"id":"https://openalex.org/C2908716204","wikidata":"https://www.wikidata.org/wiki/Q422812","display_name":"Gonadal Steroid Hormones","level":4,"score":0.428047776222229},{"id":"https://openalex.org/C2780902042","wikidata":"https://www.wikidata.org/wiki/Q177911","display_name":"Steroid","level":3,"score":0.3610146641731262},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.30953019857406616},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.23150256276130676},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18101200461387634},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012739","descriptor_name":"Gonadal Steroid Hormones","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012739","descriptor_name":"Gonadal Steroid Hormones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012739","descriptor_name":"Gonadal Steroid Hormones","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jns.2005.03.004","doi":"https://doi.org/10.1016/j.jns.2005.03.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jns.2005.03.004","pdf_url":null,"source":{"id":"https://openalex.org/S169054600","display_name":"Journal of the Neurological Sciences","issn_l":"0022-510X","issn":["0022-510X","1878-5883"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Neurological Sciences","raw_type":"journal-article"},{"id":"pmid:15878598","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15878598","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the neurological sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W127050055","https://openalex.org/W997644502","https://openalex.org/W1519441922","https://openalex.org/W1588928891","https://openalex.org/W1605865008","https://openalex.org/W1609782222","https://openalex.org/W1922888525","https://openalex.org/W1931048663","https://openalex.org/W1964814333","https://openalex.org/W1980962276","https://openalex.org/W1986313484","https://openalex.org/W1994953189","https://openalex.org/W1997883187","https://openalex.org/W2004958516","https://openalex.org/W2013082085","https://openalex.org/W2028458221","https://openalex.org/W2028934778","https://openalex.org/W2036618516","https://openalex.org/W2038205842","https://openalex.org/W2041938672","https://openalex.org/W2043729729","https://openalex.org/W2047066797","https://openalex.org/W2055910116","https://openalex.org/W2059714334","https://openalex.org/W2066462752","https://openalex.org/W2071768705","https://openalex.org/W2074788705","https://openalex.org/W2075092294","https://openalex.org/W2087022458","https://openalex.org/W2098691027","https://openalex.org/W2106274323","https://openalex.org/W2107672547","https://openalex.org/W2107815958","https://openalex.org/W2124963445","https://openalex.org/W2128514970","https://openalex.org/W2130675480","https://openalex.org/W2135551891","https://openalex.org/W2146853951","https://openalex.org/W2148186809","https://openalex.org/W2157275878","https://openalex.org/W2167042421","https://openalex.org/W2209782291","https://openalex.org/W2319459971","https://openalex.org/W2410120814","https://openalex.org/W4236672129","https://openalex.org/W6657830749","https://openalex.org/W6684500490"],"related_works":["https://openalex.org/W2074791447","https://openalex.org/W2211297114","https://openalex.org/W2513003736","https://openalex.org/W1532897909","https://openalex.org/W2007583136","https://openalex.org/W2169936175","https://openalex.org/W2015915974","https://openalex.org/W2019129843","https://openalex.org/W4311105739","https://openalex.org/W2025460629"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}