{"id":"https://openalex.org/W2008564265","doi":"https://doi.org/10.1016/s1357-2725(99)00070-9","title":"The transferrin receptor: role in health and disease","display_name":"The transferrin receptor: role in health and disease","publication_year":1999,"publication_date":"1999-10-01","ids":{"openalex":"https://openalex.org/W2008564265","doi":"https://doi.org/10.1016/s1357-2725(99)00070-9","mag":"2008564265","pmid":"https://pubmed.ncbi.nlm.nih.gov/10582342"},"language":"en","primary_location":{"id":"doi:10.1016/s1357-2725(99)00070-9","doi":"https://doi.org/10.1016/s1357-2725(99)00070-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1357-2725(99)00070-9","pdf_url":null,"source":{"id":"https://openalex.org/S183320690","display_name":"The International Journal of Biochemistry & Cell Biology","issn_l":"1357-2725","issn":["1357-2725","1878-5875"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The International Journal of Biochemistry &amp; Cell Biology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2008564265"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056211046","display_name":"Prem Ponka","orcid":"https://orcid.org/0000-0001-5835-1477","observed_orcids":["https://orcid.org/0000-0001-5835-1477"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Prem Ponka","raw_affiliation_strings":["Lady Davis Institute for Medical Research of the Sir Mortimer B. Davis Jewish General Hospital, Montreal, QC, Canada. mdpp@musica.mcgill.ca","Departments of Physiology and Medicine, McGill University, Montreal, Canada","Lady Davis Institute for Medical Research of the Sir Mortimer B. Davis Jewish General Hospital, 3755 Cote Ste-Catherine Road, Montreal, QC H3T 1E2, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lady Davis Institute for Medical Research of the Sir Mortimer B. Davis Jewish General Hospital, Montreal, QC, Canada. mdpp@musica.mcgill.ca","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356"]},{"raw_affiliation_string":"Departments of Physiology and Medicine, McGill University, Montreal, Canada","institution_ids":["https://openalex.org/I5023651"]},{"raw_affiliation_string":"Lady Davis Institute for Medical Research of the Sir Mortimer B. Davis Jewish General Hospital, 3755 Cote Ste-Catherine Road, Montreal, QC H3T 1E2, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112486642","display_name":"Chun\u2010Nam Lok","orcid":"https://orcid.org/0000-0001-9473-968X","observed_orcids":["https://orcid.org/0000-0001-9473-968X"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Chun Nam Lok","raw_affiliation_strings":["Departments of Physiology and Medicine, McGill University, Montreal, Canada","Lady Davis Institute for Medical Research of the Sir Mortimer B. Davis Jewish General Hospital, 3755 Cote Ste-Catherine Road, Montreal, QC H3T 1E2, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Physiology and Medicine, McGill University, Montreal, Canada","institution_ids":["https://openalex.org/I5023651"]},{"raw_affiliation_string":"Lady Davis Institute for Medical Research of the Sir Mortimer B. Davis Jewish General Hospital, 3755 Cote Ste-Catherine Road, Montreal, QC H3T 1E2, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5056211046"],"corresponding_institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"],"apc_list":{"value":3840,"currency":"USD","value_usd":3840},"apc_paid":null,"fwci":2.4645,"has_fulltext":false,"cited_by_count":610,"citation_normalized_percentile":{"value":0.91810345,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"31","issue":"10","first_page":"1111","last_page":"1137"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11418","display_name":"Plant Micronutrient Interactions and Effects","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11837","display_name":"Iron and Steelmaking Processes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2506","display_name":"Metals and Alloys"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transferrin-receptor","display_name":"transferrin receptor","score":1.0},{"id":"https://openalex.org/keywords/iron-absorption","display_name":"iron absorption","score":0.7979999780654907},{"id":"https://openalex.org/keywords/transferrin","display_name":"transferrin","score":0.9459999799728394},{"id":"https://openalex.org/keywords/receptor-mediated-endocytosis","display_name":"receptor-mediated endocytosis","score":0.9789999723434448},{"id":"https://openalex.org/keywords/iron-responsive-element","display_name":"iron-responsive element","score":0.8610000014305115},{"id":"https://openalex.org/keywords/iron-regulatory-proteins","display_name":"iron regulatory proteins","score":0.9959999918937683},{"id":"https://openalex.org/keywords/post-transcriptional-regulation","display_name":"post-transcriptional regulation","score":0.8169999718666077},{"id":"https://openalex.org/keywords/erythroid-cells","display_name":"erythroid cells","score":0.9359999895095825},{"id":"https://openalex.org/keywords/reticulocytes","display_name":"reticulocytes","score":0.7239999771118164},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.7120000123977661},{"id":"https://openalex.org/keywords/lymphocyte-activation","display_name":"lymphocyte activation","score":0.9150000214576721},{"id":"https://openalex.org/keywords/serum-transferrin-receptor","display_name":"serum transferrin receptor","score":0.7250000238418579},{"id":"https://openalex.org/keywords/iron-deficiency","display_name":"iron deficiency","score":0.5090000033378601},{"id":"https://openalex.org/keywords/iron-overload","display_name":"iron overload","score":0.5400000214576721}],"concepts":[{"id":"https://openalex.org/C32264632","wikidata":"https://www.wikidata.org/wiki/Q1134983","display_name":"Transferrin receptor","level":3,"score":0.9487498998641968},{"id":"https://openalex.org/C22814914","wikidata":"https://www.wikidata.org/wiki/Q410473","display_name":"Transferrin","level":2,"score":0.9189198017120361},{"id":"https://openalex.org/C102747710","wikidata":"https://www.wikidata.org/wiki/Q824237","display_name":"Endosome","level":3,"score":0.7379965782165527},{"id":"https://openalex.org/C28005876","wikidata":"https://www.wikidata.org/wiki/Q189814","display_name":"Endocytosis","level":3,"score":0.6734878420829773},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.6263496279716492},{"id":"https://openalex.org/C79747257","wikidata":"https://www.wikidata.org/wiki/Q189814","display_name":"Endocytic cycle","level":4,"score":0.60129314661026},{"id":"https://openalex.org/C139770010","wikidata":"https://www.wikidata.org/wiki/Q1339807","display_name":"Internalization","level":3,"score":0.5986735820770264},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5932086706161499},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5405811667442322},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.34901881217956543},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.30495619773864746}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000860","descriptor_name":"Hypoxia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006304","descriptor_name":"Health Status","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011990","descriptor_name":"Receptors, Transferrin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011990","descriptor_name":"Receptors, Transferrin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011990","descriptor_name":"Receptors, Transferrin","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/s1357-2725(99)00070-9","doi":"https://doi.org/10.1016/s1357-2725(99)00070-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1357-2725(99)00070-9","pdf_url":null,"source":{"id":"https://openalex.org/S183320690","display_name":"The International Journal of Biochemistry & Cell Biology","issn_l":"1357-2725","issn":["1357-2725","1878-5875"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The International Journal of Biochemistry &amp; Cell Biology","raw_type":"journal-article"},{"id":"pmid:10582342","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10582342","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The international journal of biochemistry & cell biology","raw_type":"Journal Article"},{"id":"pmh:oai:hub.hku.hk:10722/167611","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10722/167611","pdf_url":null,"source":{"id":"https://openalex.org/S4377196271","display_name":"The HKU Scholars Hub (University of Hong Kong)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I889458895","host_organization_name":"University of Hong Kong","host_organization_lineage":["https://openalex.org/I889458895"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":188,"referenced_works":["https://openalex.org/W6167358","https://openalex.org/W48239749","https://openalex.org/W55541686","https://openalex.org/W77625167","https://openalex.org/W88281208","https://openalex.org/W120993529","https://openalex.org/W138004826","https://openalex.org/W142784863","https://openalex.org/W148540643","https://openalex.org/W153121858","https://openalex.org/W153290133","https://openalex.org/W203194561","https://openalex.org/W206000071","https://openalex.org/W218318767","https://openalex.org/W220755702","https://openalex.org/W326103902","https://openalex.org/W338735814","https://openalex.org/W365679841","https://openalex.org/W647314868","https://openalex.org/W1245023662","https://openalex.org/W1481094350","https://openalex.org/W1488598317","https://openalex.org/W1490857433","https://openalex.org/W1493731365","https://openalex.org/W1495043122","https://openalex.org/W1500868688","https://openalex.org/W1504143645","https://openalex.org/W1510811131","https://openalex.org/W1513400082","https://openalex.org/W1520282358","https://openalex.org/W1522274444","https://openalex.org/W1523766194","https://openalex.org/W1526693931","https://openalex.org/W1530216928","https://openalex.org/W1536491178","https://openalex.org/W1538728268","https://openalex.org/W1542009026","https://openalex.org/W1542515219","https://openalex.org/W1543085308","https://openalex.org/W1543358558","https://openalex.org/W1558534964","https://openalex.org/W1568628619","https://openalex.org/W1569423741","https://openalex.org/W1570290272","https://openalex.org/W1583557581","https://openalex.org/W1595375154","https://openalex.org/W1605406862","https://openalex.org/W1606434495","https://openalex.org/W1607361832","https://openalex.org/W1658272758","https://openalex.org/W1664079436","https://openalex.org/W1671669579","https://openalex.org/W1778881698","https://openalex.org/W1820485696","https://openalex.org/W1872922503","https://openalex.org/W1888177932","https://openalex.org/W1962690668","https://openalex.org/W1962723822","https://openalex.org/W1963505541","https://openalex.org/W1964439650","https://openalex.org/W1965864854","https://openalex.org/W1967855521","https://openalex.org/W1967941369","https://openalex.org/W1971636557","https://openalex.org/W1977655089","https://openalex.org/W1977867185","https://openalex.org/W1983308717","https://openalex.org/W1983797954","https://openalex.org/W1985461163","https://openalex.org/W1985841747","https://openalex.org/W1986513860","https://openalex.org/W1987287339","https://openalex.org/W1987489188","https://openalex.org/W1989115860","https://openalex.org/W1991967206","https://openalex.org/W1995039589","https://openalex.org/W1996562131","https://openalex.org/W1997394534","https://openalex.org/W2000988580","https://openalex.org/W2001466383","https://openalex.org/W2002605005","https://openalex.org/W2002796914","https://openalex.org/W2003548861","https://openalex.org/W2005091504","https://openalex.org/W2005467920","https://openalex.org/W2006358233","https://openalex.org/W2006506054","https://openalex.org/W2008089774","https://openalex.org/W2012605997","https://openalex.org/W2013000450","https://openalex.org/W2014756213","https://openalex.org/W2015793968","https://openalex.org/W2017107298","https://openalex.org/W2017810128","https://openalex.org/W2019757220","https://openalex.org/W2019814232","https://openalex.org/W2020806606","https://openalex.org/W2022699060","https://openalex.org/W2026285718","https://openalex.org/W2028472887","https://openalex.org/W2029701188","https://openalex.org/W2029991413","https://openalex.org/W2032088197","https://openalex.org/W2033760796","https://openalex.org/W2034667862","https://openalex.org/W2035152288","https://openalex.org/W2037485480","https://openalex.org/W2038300452","https://openalex.org/W2039350093","https://openalex.org/W2041718235","https://openalex.org/W2043533644","https://openalex.org/W2043639947","https://openalex.org/W2043701906","https://openalex.org/W2044803565","https://openalex.org/W2046566079","https://openalex.org/W2047199243","https://openalex.org/W2047621818","https://openalex.org/W2049299765","https://openalex.org/W2049645388","https://openalex.org/W2053995668","https://openalex.org/W2056116065","https://openalex.org/W2056173274","https://openalex.org/W2061088489","https://openalex.org/W2062984171","https://openalex.org/W2065324736","https://openalex.org/W2065999538","https://openalex.org/W2066033513","https://openalex.org/W2066432115","https://openalex.org/W2066497688","https://openalex.org/W2066743380","https://openalex.org/W2067691363","https://openalex.org/W2070236309","https://openalex.org/W2070498825","https://openalex.org/W2071065354","https://openalex.org/W2071219983","https://openalex.org/W2072246224","https://openalex.org/W2074832277","https://openalex.org/W2076545723","https://openalex.org/W2081271027","https://openalex.org/W2082806735","https://openalex.org/W2086035511","https://openalex.org/W2088629685","https://openalex.org/W2089150910","https://openalex.org/W2089201245","https://openalex.org/W2091028002","https://openalex.org/W2093593540","https://openalex.org/W2093996542","https://openalex.org/W2095238965","https://openalex.org/W2098058233","https://openalex.org/W2099224788","https://openalex.org/W2099819774","https://openalex.org/W2107993264","https://openalex.org/W2108302526","https://openalex.org/W2114055862","https://openalex.org/W2116347119","https://openalex.org/W2117348012","https://openalex.org/W2119381807","https://openalex.org/W2131310817","https://openalex.org/W2133870156","https://openalex.org/W2134100982","https://openalex.org/W2141937988","https://openalex.org/W2147402578","https://openalex.org/W2147487590","https://openalex.org/W2148231718","https://openalex.org/W2148460806","https://openalex.org/W2149200346","https://openalex.org/W2150567434","https://openalex.org/W2152058159","https://openalex.org/W2152183134","https://openalex.org/W2158898858","https://openalex.org/W2160054778","https://openalex.org/W2160225986","https://openalex.org/W2161847384","https://openalex.org/W2164683251","https://openalex.org/W2176933263","https://openalex.org/W2330899270","https://openalex.org/W2407050949","https://openalex.org/W2409052516","https://openalex.org/W2414618189","https://openalex.org/W2419285129","https://openalex.org/W2441844068","https://openalex.org/W2467158718","https://openalex.org/W2548361757","https://openalex.org/W3148204004","https://openalex.org/W4248412843","https://openalex.org/W4285719527","https://openalex.org/W6680151015","https://openalex.org/W6874355654"],"related_works":["https://openalex.org/W4249401145","https://openalex.org/W2056075569","https://openalex.org/W203194561","https://openalex.org/W2626930474","https://openalex.org/W2566622139","https://openalex.org/W1538728268","https://openalex.org/W2056803937","https://openalex.org/W1589215686","https://openalex.org/W2065999538","https://openalex.org/W165773298"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":19},{"year":2025,"cited_by_count":29},{"year":2024,"cited_by_count":23},{"year":2023,"cited_by_count":28},{"year":2022,"cited_by_count":25},{"year":2021,"cited_by_count":34},{"year":2020,"cited_by_count":26},{"year":2019,"cited_by_count":32},{"year":2018,"cited_by_count":31},{"year":2017,"cited_by_count":27},{"year":2016,"cited_by_count":29},{"year":2015,"cited_by_count":23},{"year":2014,"cited_by_count":17},{"year":2013,"cited_by_count":20},{"year":2012,"cited_by_count":15}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}
