{"id":"https://openalex.org/W2008432452","doi":"https://doi.org/10.4236/ijcm.2014.55031","title":"Clinical Spectrum of Infective Endocarditis in a Tertiary Care Centre in Western India: A Prospective Study","display_name":"Clinical Spectrum of Infective Endocarditis in a Tertiary Care Centre in Western India: A Prospective Study","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2008432452","doi":"https://doi.org/10.4236/ijcm.2014.55031","mag":"2008432452"},"language":"en","primary_location":{"id":"doi:10.4236/ijcm.2014.55031","doi":"https://doi.org/10.4236/ijcm.2014.55031","is_oa":true,"landing_page_url":"https://doi.org/10.4236/ijcm.2014.55031","pdf_url":"http://www.scirp.org/journal/PaperDownload.aspx?paperID=43772","source":{"id":"https://openalex.org/S4210220005","display_name":"International Journal of Clinical Medicine","issn_l":"2158-284X","issn":["2158-284X","2158-2882"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320480","host_organization_name":"Scientific Research Publishing","host_organization_lineage":["https://openalex.org/P4310320480"],"host_organization_lineage_names":["Scientific Research Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Clinical Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://www.scirp.org/journal/PaperDownload.aspx?paperID=43772","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052873478","display_name":"Sharad Jain","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Sharad R. Jain","raw_affiliation_strings":["Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre, Ahmedabad, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre, Ahmedabad, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053055884","display_name":"Jayesh Prajapati","orcid":"https://orcid.org/0000-0002-6387-6822","observed_orcids":["https://orcid.org/0000-0002-6387-6822","https://orcid.org/0009-0001-9875-821X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jayesh S. Prajapati","raw_affiliation_strings":["Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre, Ahmedabad, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre, Ahmedabad, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054320174","display_name":"Manjunath A. Phasalkar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Manjunath A. Phasalkar","raw_affiliation_strings":["Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre, Ahmedabad, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre, Ahmedabad, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111540741","display_name":"Bhavesh Roy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bhavesh H. Roy","raw_affiliation_strings":["Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre, Ahmedabad, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre, Ahmedabad, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088090327","display_name":"Ashwal A. Jayram","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ashwal A. Jayram","raw_affiliation_strings":["Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre, Ahmedabad, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre, Ahmedabad, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059110345","display_name":"Shaurinkumar R. Shah","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shaurinkumar R. Shah","raw_affiliation_strings":["Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre, Ahmedabad, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre, Ahmedabad, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066205665","display_name":"Tarandeep Singh","orcid":"https://orcid.org/0000-0003-2377-604X","observed_orcids":["https://orcid.org/0000-0003-2377-604X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tarandeep Singh","raw_affiliation_strings":["Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre, Ahmedabad, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre, Ahmedabad, India","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049535360","display_name":"Ashok S. Thakkar","orcid":"https://orcid.org/0000-0002-0051-4939","observed_orcids":["https://orcid.org/0000-0002-0051-4939"]},"institutions":[{"id":"https://openalex.org/I4210109275","display_name":"SMT (India)","ror":"https://ror.org/01vm4bk04","country_code":"IN","type":"company","lineage":["https://openalex.org/I4210109275"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ashok S. Thakkar","raw_affiliation_strings":["Department of Clinical Trials, Sahajanand Medical Tech. Pvt. Ltd., Surat, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Trials, Sahajanand Medical Tech. Pvt. Ltd., Surat, India","institution_ids":["https://openalex.org/I4210109275"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5052873478"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8825,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.76694915,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"05","issue":"05","first_page":"177","last_page":"187"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11551","display_name":"Infective Endocarditis Diagnosis and Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11551","display_name":"Infective Endocarditis Diagnosis and Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11153","display_name":"Streptococcal Infections and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/infective-endocarditis","display_name":"infective endocarditis","score":1.0},{"id":"https://openalex.org/keywords/microbiological-spectrum","display_name":"microbiological spectrum","score":0.8610000014305115},{"id":"https://openalex.org/keywords/rheumatic-heart-disease","display_name":"rheumatic heart disease","score":0.8659999966621399},{"id":"https://openalex.org/keywords/septic-shock","display_name":"septic shock","score":0.6940000057220459},{"id":"https://openalex.org/keywords/congestive-heart-failure","display_name":"congestive heart failure","score":0.9049999713897705},{"id":"https://openalex.org/keywords/neurological-complications","display_name":"neurological complications","score":0.7889999747276306},{"id":"https://openalex.org/keywords/kidney-failure","display_name":"renal failure","score":0.9829999804496765},{"id":"https://openalex.org/keywords/in-hospital-mortality","display_name":"in-hospital mortality","score":0.8460000157356262},{"id":"https://openalex.org/keywords/risk-factors-for-mortality","display_name":"mortality risk factors","score":0.8230000138282776},{"id":"https://openalex.org/keywords/cardiac-surgery","display_name":"cardiac surgery","score":0.7260000109672546},{"id":"https://openalex.org/keywords/echocardiographic-features","display_name":"echocardiographic features","score":0.7799999713897705},{"id":"https://openalex.org/keywords/blood-culture-positivity","display_name":"blood culture positivity","score":0.5080000162124634}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9299717545509338},{"id":"https://openalex.org/C2780176578","wikidata":"https://www.wikidata.org/wiki/Q2450598","display_name":"Infective endocarditis","level":2,"score":0.7400105595588684},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.7366811633110046},{"id":"https://openalex.org/C2777628635","wikidata":"https://www.wikidata.org/wiki/Q1765564","display_name":"Septic shock","level":3,"score":0.6926429867744446},{"id":"https://openalex.org/C2775872228","wikidata":"https://www.wikidata.org/wiki/Q82504","display_name":"Endocarditis","level":2,"score":0.5676332712173462},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.5563691854476929},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.5085533857345581},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5040284991264343},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.4398777484893799},{"id":"https://openalex.org/C2778621155","wikidata":"https://www.wikidata.org/wiki/Q576349","display_name":"Encephalopathy","level":2,"score":0.41252854466438293},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.37508684396743774},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3536503314971924},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3455736041069031},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.23662734031677246},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.4236/ijcm.2014.55031","doi":"https://doi.org/10.4236/ijcm.2014.55031","is_oa":true,"landing_page_url":"https://doi.org/10.4236/ijcm.2014.55031","pdf_url":"http://www.scirp.org/journal/PaperDownload.aspx?paperID=43772","source":{"id":"https://openalex.org/S4210220005","display_name":"International Journal of Clinical Medicine","issn_l":"2158-284X","issn":["2158-284X","2158-2882"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320480","host_organization_name":"Scientific Research Publishing","host_organization_lineage":["https://openalex.org/P4310320480"],"host_organization_lineage_names":["Scientific Research Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Clinical Medicine","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.4236/ijcm.2014.55031","doi":"https://doi.org/10.4236/ijcm.2014.55031","is_oa":true,"landing_page_url":"https://doi.org/10.4236/ijcm.2014.55031","pdf_url":"http://www.scirp.org/journal/PaperDownload.aspx?paperID=43772","source":{"id":"https://openalex.org/S4210220005","display_name":"International Journal of Clinical Medicine","issn_l":"2158-284X","issn":["2158-284X","2158-2882"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320480","host_organization_name":"Scientific Research Publishing","host_organization_lineage":["https://openalex.org/P4310320480"],"host_organization_lineage_names":["Scientific Research Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Clinical Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2008432452.pdf","grobid_xml":"https://content.openalex.org/works/W2008432452.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W1977144861","https://openalex.org/W1994713282","https://openalex.org/W2013603251","https://openalex.org/W2016967585","https://openalex.org/W2023876883","https://openalex.org/W2027712206","https://openalex.org/W2031498115","https://openalex.org/W2038194995","https://openalex.org/W2063724714","https://openalex.org/W2065483586","https://openalex.org/W2090824616","https://openalex.org/W2096617024","https://openalex.org/W2118546214","https://openalex.org/W2125779252","https://openalex.org/W2134509750","https://openalex.org/W2135173846","https://openalex.org/W2137434220","https://openalex.org/W2152744485","https://openalex.org/W2153989479","https://openalex.org/W2154906707","https://openalex.org/W2287060682","https://openalex.org/W2414101801","https://openalex.org/W3032238784","https://openalex.org/W4211013927"],"related_works":["https://openalex.org/W1977144861","https://openalex.org/W4389029484","https://openalex.org/W2750257215","https://openalex.org/W303513492","https://openalex.org/W4387277773","https://openalex.org/W2746535481","https://openalex.org/W2027712206","https://openalex.org/W1739458707","https://openalex.org/W4401477455","https://openalex.org/W2019445255"],"abstract_inverted_index":{"OBJECTIVES:":[0],"We":[1,86],"examined":[2],"the":[3,40,49,70,74,84,97,119,245,260,287],"microbiological":[4],"spectrum,":[5],"clinical":[6],"profile,":[7],"echocardiographic":[8],"features":[9,91],"and":[10,34,63,92,144,185,224,247,252,272],"in-hospital":[11],"outcomes":[12,93,288],"of":[13,21,25,53,61,136,191,230,235,289],"patients":[14,71,89,197],"with":[15,108,138],"definitive":[16,26,51,77],"IE.":[17,201],"METHODS:":[18],"A":[19],"total":[20,203],"75":[22],"consecutive":[23,50],"cases":[24,52,153,192],"infective":[27,236,275],"endocarditis":[28,237,276],"(IE),":[29],"admitted":[30,55],"between":[31],"January":[32,35],"2011":[33],"2013,":[36],"were":[37,81,148,227],"included":[38,82],"in":[39,83,96,134,150,157,161,165,169,174,180,183,188,204,240,265],"study.":[41,85],"This":[42],"was":[43,103,118,132,208],"a":[44,109,249],"prospective":[45],"study":[46],"enrolling":[47],"all":[48],"IE":[54,80],"at":[56],"U.":[57],"N.":[58],"Mehta":[59],"Institute":[60],"Cardiology":[62],"Research":[64],"Centre":[65],"(UNMICRC),":[66],"Ahmedabad,":[67],"India.":[68],"Only":[69,194],"who":[72],"met":[73],"modified":[75],"Duke\u2019s":[76],"criteria":[78],"for":[79,200,274],"compared":[87,243],"enrolled":[88],"clinicoepidemiologic":[90],"to":[94,244,285],"subjects":[95],"west.":[98],"RESULTS:":[99],"The":[100,113,129,202,233,254,268],"mean":[101],"age":[102,221],"27.46":[104],"\u00b1":[105],"17.11":[106],"years":[107,223],"male":[110],"preponderance":[111],"(2.26:1).":[112],"rheumatic":[114,255],"heart":[115,126,155,215,256,263],"disease":[116,122,127,257,264],"(41.3%)":[117],"commonest":[120,139,261],"underlying":[121,262],"followed":[123],"by":[124],"coronary":[125],"(34.7%).":[128],"blood":[130],"culture":[131,269],"positive":[133],"40%":[135],"episodes":[137],"organisms":[140],"being":[141],"staphylococci":[142],"(16%)":[143,196],"streptococci":[145],"(12%).":[146],"Complications":[147],"cardiovascular":[149],"40":[151],"(53.3%)":[152],"(congestive":[154],"failure":[156,187],"42.7%,":[158],"atrioventricular":[159],"block":[160],"6.7%),":[162],"septic":[163,225],"shock":[164,226],"20":[166,189,222],"(26.7%),":[167],"neurological":[168,219],"23":[170],"(30.7%)":[171],"(cerebrovascular":[172],"stroke":[173],"20%,":[175],"central":[176],"nervous":[177],"system":[178],"hemorrhage":[179],"5.3%,":[181],"encephalopathy":[182],"5.3%)":[184],"renal":[186,217],"(26.7%)":[190],"respectively.":[193],"12":[195],"underwent":[198],"surgery":[199,273,282],"hospital":[205],"mortality":[206],"rate":[207],"22":[209],"(29.3%).":[210],"On":[211],"multivariate":[212],"analysis,":[213],"congestive":[214],"failure,":[216,218],"abnormalities,":[220],"independent":[228],"predictors":[229],"mortality.":[231,253],"CONCLUSIONS:":[232],"spectrum":[234],"is":[238,258],"different":[239],"Indian":[241],"population":[242],"west":[246],"carries":[248],"substantial":[250],"morbidity":[251],"still":[259],"our":[266],"population.":[267],"positivity":[270],"rates":[271],"are":[277],"unacceptably":[278],"low.":[279],"Early":[280],"cardiac":[281],"may":[283],"help":[284],"improve":[286],"these":[290],"patients.":[291]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}