{"id":"https://openalex.org/W2008336607","doi":"https://doi.org/10.1002/j.1550-8528.1998.tb00347.x","title":"Serum Leptin Concentrations and Weight Gain in Postobese, Postmenopausal Women","display_name":"Serum Leptin Concentrations and Weight Gain in Postobese, Postmenopausal Women","publication_year":1998,"publication_date":"1998-07-01","ids":{"openalex":"https://openalex.org/W2008336607","doi":"https://doi.org/10.1002/j.1550-8528.1998.tb00347.x","mag":"2008336607","pmid":"https://pubmed.ncbi.nlm.nih.gov/9688101"},"language":"en","primary_location":{"id":"doi:10.1002/j.1550-8528.1998.tb00347.x","doi":"https://doi.org/10.1002/j.1550-8528.1998.tb00347.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.1550-8528.1998.tb00347.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1550-8528.1998.tb00347.x","source":{"id":"https://openalex.org/S68541908","display_name":"Obesity Research","issn_l":"1071-7323","issn":["1071-7323","1550-8528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obesity Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1550-8528.1998.tb00347.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063125618","display_name":"Tim R. Nagy","orcid":"https://orcid.org/0000-0002-2371-7114","observed_orcids":["https://orcid.org/0000-0002-2371-7114"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Tim R. Nagy","raw_affiliation_strings":["Department of Nutrition Sciences, School of Health Related Professions, University of Alabama at Birmingham, 35294-3360, USA","Department of Nutrition Sciences, School of Health Related Professions, University of Alabama at Birmingham, Birmingham, AL","Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition Sciences, School of Health Related Professions, University of Alabama at Birmingham, 35294-3360, USA","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"Department of Nutrition Sciences, School of Health Related Professions, University of Alabama at Birmingham, Birmingham, AL","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067864889","display_name":"Susan Lane Davies","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan L. Davies","raw_affiliation_strings":["Department of Nutrition Sciences, School of Health Related Professions, University of Alabama at Birmingham, Birmingham, AL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition Sciences, School of Health Related Professions, University of Alabama at Birmingham, Birmingham, AL","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110131906","display_name":"Gary R. Hunter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary R. Hunter","raw_affiliation_strings":["Department of Human Studies, School of Education, University of Alabama at Birmingham, Birmingham, AL","Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Studies, School of Education, University of Alabama at Birmingham, Birmingham, AL","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108452752","display_name":"Betty E. Darnell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Betty Darnell","raw_affiliation_strings":["General Clinical Research Center, University of Alabama at Birmingham, Birmingham, AL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"General Clinical Research Center, University of Alabama at Birmingham, Birmingham, AL","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109903848","display_name":"Roland L. Weinsier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roland L. Weinsier","raw_affiliation_strings":["Department of Nutrition Sciences, School of Health Related Professions, University of Alabama at Birmingham, Birmingham, AL","Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition Sciences, School of Health Related Professions, University of Alabama at Birmingham, Birmingham, AL","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL","institution_ids":["https://openalex.org/I32389192"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5063125618"],"corresponding_institution_ids":["https://openalex.org/I32389192"],"apc_list":null,"apc_paid":null,"fwci":1.3322,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.80569307,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"6","issue":"4","first_page":"257","last_page":"261"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10263","display_name":"Eating Disorders and Behaviors","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leptin","display_name":"leptin","score":0.9729999899864197},{"id":"https://openalex.org/keywords/weight-regain","display_name":"weight regain","score":0.828000009059906},{"id":"https://openalex.org/keywords/weight-loss","display_name":"weight loss","score":0.8220000267028809},{"id":"https://openalex.org/keywords/postmenopausal-women","display_name":"postmenopausal women","score":0.8790000081062317},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.8479999899864197},{"id":"https://openalex.org/keywords/body-fat","display_name":"fat mass","score":0.7580000162124634},{"id":"https://openalex.org/keywords/body-composition","display_name":"body composition","score":0.8320000171661377},{"id":"https://openalex.org/keywords/low-calorie-diet","display_name":"hypocaloric diet","score":0.8479999899864197},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.5640000104904175},{"id":"https://openalex.org/keywords/body-fat-percentage","display_name":"body fat percentage","score":0.722000002861023},{"id":"https://openalex.org/keywords/metabolic-ward","display_name":"metabolic ward","score":0.4020000100135803}],"concepts":[{"id":"https://openalex.org/C2780613262","wikidata":"https://www.wikidata.org/wiki/Q223739","display_name":"Leptin","level":3,"score":0.8943483829498291},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7325326204299927},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7277149558067322},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.7058656215667725},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.682635486125946},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6758255958557129},{"id":"https://openalex.org/C544821477","wikidata":"https://www.wikidata.org/wiki/Q718113","display_name":"Weight loss","level":3,"score":0.6053240895271301},{"id":"https://openalex.org/C2993503589","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Fat mass","level":3,"score":0.4986572265625},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.4679262638092041},{"id":"https://openalex.org/C2780320433","wikidata":"https://www.wikidata.org/wiki/Q3403879","display_name":"Weight gain","level":3,"score":0.44567206501960754},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.42090386152267456},{"id":"https://openalex.org/C111214947","wikidata":"https://www.wikidata.org/wiki/Q22907290","display_name":"Classification of obesity","level":4,"score":0.4184817671775818}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001823","descriptor_name":"Body Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015430","descriptor_name":"Weight Gain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017698","descriptor_name":"Postmenopause","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D020738","descriptor_name":"Leptin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/j.1550-8528.1998.tb00347.x","doi":"https://doi.org/10.1002/j.1550-8528.1998.tb00347.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.1550-8528.1998.tb00347.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1550-8528.1998.tb00347.x","source":{"id":"https://openalex.org/S68541908","display_name":"Obesity Research","issn_l":"1071-7323","issn":["1071-7323","1550-8528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obesity Research","raw_type":"journal-article"},{"id":"pmid:9688101","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9688101","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obesity research","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/j.1550-8528.1998.tb00347.x","doi":"https://doi.org/10.1002/j.1550-8528.1998.tb00347.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.1550-8528.1998.tb00347.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1550-8528.1998.tb00347.x","source":{"id":"https://openalex.org/S68541908","display_name":"Obesity Research","issn_l":"1071-7323","issn":["1071-7323","1550-8528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obesity Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.7200000286102295,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2117367422","display_name":null,"funder_award_id":"R01 DK-38491","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G2753962916","display_name":"POSTPRANDIAL THERMOGENESIS &OBESITY: CAUSE OR EFFECT","funder_award_id":"1r01dk038491-01a1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4839546434","display_name":"Exercise Intensity, Metabolic Rate & Insulin Sensitivity","funder_award_id":"R01DK049779","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G5249202955","display_name":null,"funder_award_id":"RR 32","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2008336607.pdf","grobid_xml":"https://content.openalex.org/works/W2008336607.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W194145145","https://openalex.org/W1891666168","https://openalex.org/W1977617928","https://openalex.org/W1992077067","https://openalex.org/W1999338955","https://openalex.org/W2011956103","https://openalex.org/W2015479739","https://openalex.org/W2016675613","https://openalex.org/W2020063446","https://openalex.org/W2032758921","https://openalex.org/W2047985768","https://openalex.org/W2060682066","https://openalex.org/W2091087465","https://openalex.org/W2114675403","https://openalex.org/W2117995721","https://openalex.org/W2118579666","https://openalex.org/W2139719812","https://openalex.org/W2149678818","https://openalex.org/W2152857988","https://openalex.org/W2160064508","https://openalex.org/W2237359533","https://openalex.org/W2321598419","https://openalex.org/W2341183108","https://openalex.org/W2785259924","https://openalex.org/W4231025713","https://openalex.org/W4254537967"],"related_works":["https://openalex.org/W2004154305","https://openalex.org/W2126326574","https://openalex.org/W1981858263","https://openalex.org/W7034143964","https://openalex.org/W2001102352","https://openalex.org/W2026903331","https://openalex.org/W2186639700","https://openalex.org/W2085760420","https://openalex.org/W2003594113","https://openalex.org/W1987037979"],"abstract_inverted_index":{"OBJECTIVE:":[0],"This":[1],"study":[2,251],"was":[3,252],"designed":[4],"to":[5,49,79,187],"determine":[6],"if":[7],"serum":[8,33,137,171],"leptin":[9,34,138,149,172,236],"concentrations":[10,35,139,150,173,234],"(adjusted":[11,174],"for":[12,175],"fat":[13,105,128,156,176,197,215],"mass)":[14,177],"after":[15,71,240],"weight":[16,24,64,74,82,91,191,238,241],"loss":[17,75,99],"on":[18,38],"a":[19,46,72],"low-calorie":[20],"diet":[21],"predict":[22,237],"subsequent":[23],"gain.":[25],"RESEARCH":[26],"METHODS":[27],"AND":[28],"PROCEDURES:":[29],"Body":[30],"composition":[31,94],"and":[32,63,70,92,136,162,166,181,195,202,210,217],"were":[36,52,95,151,184],"determined":[37],"14":[39],"moderately":[40],"obese,":[41],"postmenopausal,":[42],"nondiabetic":[43],"women":[44],"with":[45,155],"familial":[47],"predisposition":[48],"obesity.":[50],"Assessments":[51],"obtained":[53],"under":[54],"tightly":[55],"controlled":[56],"metabolic":[57],"ward":[58],"conditions":[59],"of":[60,76,235,247],"macronutrient":[61],"intake":[62],"maintenance":[65],"both":[66,159],"before":[67],"(obese":[68],"state)":[69],"mean":[73],"12.0":[77],"kg":[78],"normal":[80],"body":[81,90,93,115,127,190,204,214],"(postobese":[83],"state).":[84],"Four":[85],"years":[86],"later,":[87],"without":[88],"intervention,":[89],"reassessed.":[96],"RESULTS:":[97],"Weight":[98],"resulted":[100],"in":[101,104,158,178,189,249],"significant":[102],"decreases":[103],"mass":[106,116,157,198,205],"(29.7":[107],"+/-":[108,112,123,130,134,141,145],"5.4":[109],"vs.":[110,121,132,143],"20.3":[111],"4.7;":[113],"kg),":[114],"index":[117,206],"(27.7":[118],"+/":[119],"1.6":[120],"23.0":[122],"1.5;":[124],"kg/m2),":[125],"percent":[126,213],"(40.7":[129],"4.3":[131],"33.1":[133],"5.0),":[135],"(31.8":[140],"16.0":[142],"11.5":[144],"5.4;":[146],"ng/mL).":[147],"Serum":[148],"positively":[152],"correlated":[153],"(p<0.05)":[154],"the":[160,179,220,229,245],"obese":[161,180],"postobese":[163,182],"states":[164,183],"(r=0.67":[165],"r=0.56,":[167],"respectively).":[168],"However,":[169,243],"residual":[170],"not":[185,227],"related":[186],"changes":[188],"(p":[192,199,207],"=":[193,200,208],"0.61":[194],"0.52),":[196],"0.72":[201],"0.42),":[203],"0.59":[209],"0.33),":[211],"or":[212],"(p=0.84":[216],"0.46)":[218],"over":[219],"follow-up":[221],"period.":[222],"DISCUSSION:":[223],"These":[224],"finding":[225],"do":[226],"support":[228],"hypothesis":[230],"that":[231],"relatively":[232],"low":[233],"regain":[239],"loss.":[242],"because":[244],"number":[246],"subjects":[248],"this":[250],"limited,":[253],"further":[254],"studies":[255],"are":[256],"warranted.":[257]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}