{"id":"https://openalex.org/W2008285658","doi":"https://doi.org/10.1590/s0004-27302004000100016","title":"Disfun\u00e7\u00f5es m\u00ednimas da tir\u00f3ide: hipotiroidismo subcl\u00ednico e hipertiroidismo subcl\u00ednico","display_name":"Disfun\u00e7\u00f5es m\u00ednimas da tir\u00f3ide: hipotiroidismo subcl\u00ednico e hipertiroidismo subcl\u00ednico","publication_year":2004,"publication_date":"2004-02-01","ids":{"openalex":"https://openalex.org/W2008285658","doi":"https://doi.org/10.1590/s0004-27302004000100016","mag":"2008285658","pmid":"https://pubmed.ncbi.nlm.nih.gov/15611827"},"language":"pt","primary_location":{"id":"doi:10.1590/s0004-27302004000100016","doi":"https://doi.org/10.1590/s0004-27302004000100016","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s0004-27302004000100016","pdf_url":"https://www.scielo.br/j/abem/a/4vpxTNkxwcsT49XMfSqWtXm/?lang=pt&format=pdf","source":{"id":"https://openalex.org/S15262226","display_name":"Arquivos Brasileiros de Endocrinologia & Metabologia","issn_l":"0004-2730","issn":["0004-2730","1677-9487"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4310319680","host_organization_name":"Editora da Universidade de S\u00e3o Paulo","host_organization_lineage":["https://openalex.org/P4310319680"],"host_organization_lineage_names":["Editora da Universidade de S\u00e3o Paulo"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arquivos Brasileiros de Endocrinologia & Metabologia","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.scielo.br/j/abem/a/4vpxTNkxwcsT49XMfSqWtXm/?lang=pt&format=pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078271502","display_name":"Jo\u00e3o Hamilton Romaldini","orcid":"https://orcid.org/0000-0002-8369-0945","observed_orcids":["https://orcid.org/0000-0002-8369-0945"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jo\u00e3o Hamilton Romaldini","raw_affiliation_strings":["PUC; Escola Estadual de Medicina; IAMSPE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"PUC; Escola Estadual de Medicina; IAMSPE","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042776454","display_name":"Jos\u00e9 Augusto Sgarbi","orcid":"https://orcid.org/0000-0001-7187-984X","observed_orcids":["https://orcid.org/0000-0001-7187-984X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Augusto Sgarbi","raw_affiliation_strings":["PUC; Escola Estadual de Medicina; IAMSPE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"PUC; Escola Estadual de Medicina; IAMSPE","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103460934","display_name":"Chady S. Farah","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chady Satt Farah","raw_affiliation_strings":["PUC; Escola Estadual de Medicina; IAMSPE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"PUC; Escola Estadual de Medicina; IAMSPE","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2949,"has_fulltext":true,"cited_by_count":22,"citation_normalized_percentile":{"value":0.3054755,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"48","issue":"1","first_page":"147","last_page":"158"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11728","display_name":"Thyroid and Parathyroid Surgery","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/subclinical-hypothyroidism","display_name":"subclinical hypothyroidism","score":0.9990000128746033},{"id":"https://openalex.org/keywords/subclinical-hyperthyroidism","display_name":"subclinical hyperthyroidism","score":1.0},{"id":"https://openalex.org/keywords/thyroid-disease","display_name":"thyroid dysfunction","score":0.7860000133514404},{"id":"https://openalex.org/keywords/thyroid-stimulating-hormone","display_name":"thyroid-stimulating hormone","score":0.7080000042915344},{"id":"https://openalex.org/keywords/free-thyroxine","display_name":"free thyroxine","score":0.6809999942779541},{"id":"https://openalex.org/keywords/free-t3","display_name":"free T3","score":0.8859999775886536},{"id":"https://openalex.org/keywords/cholesterol","display_name":"cholesterol","score":0.42399999499320984},{"id":"https://openalex.org/keywords/ldl-c","display_name":"LDL-C","score":0.703000009059906},{"id":"https://openalex.org/keywords/levothyroxine","display_name":"levothyroxine","score":0.9380000233650208},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"atrial fibrillation","score":0.8790000081062317},{"id":"https://openalex.org/keywords/left-ventricular-mass","display_name":"left ventricular mass","score":0.8320000171661377},{"id":"https://openalex.org/keywords/bone-mineral-density","display_name":"bone mineral density","score":0.6579999923706055},{"id":"https://openalex.org/keywords/thyroid-autoantibodies","display_name":"thyroid autoantibodies","score":0.7599999904632568},{"id":"https://openalex.org/keywords/treatment-thresholds","display_name":"treatment thresholds","score":0.546999990940094},{"id":"https://openalex.org/keywords/elderly-patients","display_name":"elderly patients","score":0.4300000071525574}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5666514039039612},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3578214645385742}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006980","descriptor_name":"Hyperthyroidism","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D006980","descriptor_name":"Hyperthyroidism","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D006980","descriptor_name":"Hyperthyroidism","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D007037","descriptor_name":"Hypothyroidism","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D007037","descriptor_name":"Hypothyroidism","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D007037","descriptor_name":"Hypothyroidism","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1590/s0004-27302004000100016","doi":"https://doi.org/10.1590/s0004-27302004000100016","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s0004-27302004000100016","pdf_url":"https://www.scielo.br/j/abem/a/4vpxTNkxwcsT49XMfSqWtXm/?lang=pt&format=pdf","source":{"id":"https://openalex.org/S15262226","display_name":"Arquivos Brasileiros de Endocrinologia & Metabologia","issn_l":"0004-2730","issn":["0004-2730","1677-9487"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4310319680","host_organization_name":"Editora da Universidade de S\u00e3o Paulo","host_organization_lineage":["https://openalex.org/P4310319680"],"host_organization_lineage_names":["Editora da Universidade de S\u00e3o Paulo"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arquivos Brasileiros de Endocrinologia & Metabologia","raw_type":"journal-article"},{"id":"pmid:15611827","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15611827","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arquivos brasileiros de endocrinologia e metabologia","raw_type":"English Abstract"},{"id":"pmh:oai:scielo:S0004-27302004000100016","doi":null,"is_oa":true,"landing_page_url":"http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302004000100016","pdf_url":null,"source":{"id":"https://openalex.org/S4306402308","display_name":"The Scientific Electronic Library Online (Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210116822","host_organization_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","host_organization_lineage":["https://openalex.org/I4210116822"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Arquivos Brasileiros de Endocrinologia & Metabologia v.48 n.1 2004","raw_type":"info:eu-repo/semantics/other"},{"id":"mag:2513438873","doi":null,"is_oa":false,"landing_page_url":"https://www.scielo.br/pdf/abem/v48n1/19528.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1590/s0004-27302004000100016","doi":"https://doi.org/10.1590/s0004-27302004000100016","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s0004-27302004000100016","pdf_url":"https://www.scielo.br/j/abem/a/4vpxTNkxwcsT49XMfSqWtXm/?lang=pt&format=pdf","source":{"id":"https://openalex.org/S15262226","display_name":"Arquivos Brasileiros de Endocrinologia & Metabologia","issn_l":"0004-2730","issn":["0004-2730","1677-9487"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4310319680","host_organization_name":"Editora da Universidade de S\u00e3o Paulo","host_organization_lineage":["https://openalex.org/P4310319680"],"host_organization_lineage_names":["Editora da Universidade de S\u00e3o Paulo"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arquivos Brasileiros de Endocrinologia & Metabologia","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2008285658.pdf","grobid_xml":"https://content.openalex.org/works/W2008285658.grobid-xml"},"referenced_works_count":107,"referenced_works":["https://openalex.org/W39789357","https://openalex.org/W1545572940","https://openalex.org/W1597094273","https://openalex.org/W1635818019","https://openalex.org/W1963633722","https://openalex.org/W1968007805","https://openalex.org/W1970709107","https://openalex.org/W1971576580","https://openalex.org/W1976274614","https://openalex.org/W1978559629","https://openalex.org/W1981012541","https://openalex.org/W1982304029","https://openalex.org/W1986798550","https://openalex.org/W1992692011","https://openalex.org/W1993358990","https://openalex.org/W1995620508","https://openalex.org/W2001684491","https://openalex.org/W2004525296","https://openalex.org/W2006323076","https://openalex.org/W2007901261","https://openalex.org/W2008199023","https://openalex.org/W2008325595","https://openalex.org/W2014395731","https://openalex.org/W2014820821","https://openalex.org/W2016050393","https://openalex.org/W2026809390","https://openalex.org/W2027736044","https://openalex.org/W2029463060","https://openalex.org/W2030961764","https://openalex.org/W2037436624","https://openalex.org/W2039812408","https://openalex.org/W2040416944","https://openalex.org/W2042626693","https://openalex.org/W2043001655","https://openalex.org/W2044357536","https://openalex.org/W2048221575","https://openalex.org/W2048304052","https://openalex.org/W2048654799","https://openalex.org/W2049139474","https://openalex.org/W2053935196","https://openalex.org/W2053970647","https://openalex.org/W2056666045","https://openalex.org/W2056889736","https://openalex.org/W2058853709","https://openalex.org/W2066467884","https://openalex.org/W2069934475","https://openalex.org/W2073919574","https://openalex.org/W2074183551","https://openalex.org/W2077688299","https://openalex.org/W2078996989","https://openalex.org/W2083172499","https://openalex.org/W2085556990","https://openalex.org/W2087975771","https://openalex.org/W2088199680","https://openalex.org/W2089290117","https://openalex.org/W2089937750","https://openalex.org/W2090982939","https://openalex.org/W2093333241","https://openalex.org/W2094912659","https://openalex.org/W2096560123","https://openalex.org/W2097165278","https://openalex.org/W2099677070","https://openalex.org/W2099864259","https://openalex.org/W2100106207","https://openalex.org/W2113836384","https://openalex.org/W2114216607","https://openalex.org/W2116450237","https://openalex.org/W2119115130","https://openalex.org/W2119950851","https://openalex.org/W2120126551","https://openalex.org/W2122733513","https://openalex.org/W2133547068","https://openalex.org/W2137462208","https://openalex.org/W2140936682","https://openalex.org/W2142296338","https://openalex.org/W2144427679","https://openalex.org/W2147334676","https://openalex.org/W2148113299","https://openalex.org/W2151074096","https://openalex.org/W2152497658","https://openalex.org/W2157668237","https://openalex.org/W2159860352","https://openalex.org/W2162952990","https://openalex.org/W2163598942","https://openalex.org/W2164783415","https://openalex.org/W2170140773","https://openalex.org/W2238551435","https://openalex.org/W2273068525","https://openalex.org/W2282060572","https://openalex.org/W2285909100","https://openalex.org/W2324924602","https://openalex.org/W2325705904","https://openalex.org/W2334419274","https://openalex.org/W2335515807","https://openalex.org/W2336978010","https://openalex.org/W2408843773","https://openalex.org/W4231768906","https://openalex.org/W4234045237","https://openalex.org/W4236934658","https://openalex.org/W4241404748","https://openalex.org/W4243364521","https://openalex.org/W4243976325","https://openalex.org/W4248085597","https://openalex.org/W4249320909","https://openalex.org/W4250164051","https://openalex.org/W4285719527","https://openalex.org/W6682425701"],"related_works":["https://openalex.org/W2513438873","https://openalex.org/W2185310253","https://openalex.org/W2924438217","https://openalex.org/W6944012187","https://openalex.org/W2795430732","https://openalex.org/W4283366314","https://openalex.org/W7160865616","https://openalex.org/W2594066124","https://openalex.org/W115816897","https://openalex.org/W4251814473"],"abstract_inverted_index":{"Subclinical":[0],"hypothyroidism":[1],"(SHT)":[2,20],"and":[3,14,29,44,49,61,79,84,103,125,148],"subclinical":[4],"hyperthyroidism":[5],"(SCH)":[6,23],"are":[7,34,46,108],"defined":[8],"as":[9],"normal":[10],"serum":[11,24,118,136],"free":[12],"T4":[13],"T3":[15],"levels":[16,120,138],"associated":[17,72],"with":[18,68,73,91],"elevated":[19,48],"or":[21],"subnormal":[22],"TSH":[25,119,137],"levels,":[26],"respectively.":[27],"Symptoms":[28],"signs":[30],"of":[31,113,127,146],"thyroid":[32,128],"dysfunction":[33,86],"scarce.":[35],"The":[36],"prevalence":[37],"is":[38,57,71,96,115],"low.":[39],"In":[40],"SHT,":[41],"total":[42],"cholesterol":[43],"LDL-C":[45],"modestly":[47],"levothyroxine":[50],"may":[51],"influence":[52],"the":[53,144],"lipids":[54],"levels.":[55],"There":[56],"decreased":[58],"cardiac":[59,77],"contractility":[60,78],"increased":[62,76],"peripheral":[63],"vascular":[64],"resistance":[65],"that":[66,87],"improve":[67],"treatment.":[69],"SCH":[70,131],"atrial":[74],"fibrillation,":[75],"left":[80],"ventricular":[81],"mass,":[82],"diastolic":[83],"systolic":[85],"can":[88],"be":[89,133],"reversed":[90],"beta-adrenergic":[92],"antagonists.":[93],"Bone":[94],"density":[95],"reduced":[97],"in":[98,105,110,143,149],"SCH.":[99],"Depression,":[100],"panic":[101],"disorders":[102],"alterations":[104],"cognitive":[106],"testing":[107],"frequent":[109],"SHT.":[111],"Treatment":[112],"SHT":[114],"recommended":[116],"for":[117,135],"greater":[121],"than":[122,140],"8":[123],"mU/L":[124],"presence":[126,145],"antibodies.":[129],"Endogenous":[130],"should":[132],"treated":[134],"less":[139],"0.1":[141],"mU/L,":[142],"symptoms":[147],"elderly":[150],"patents.":[151]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}