{"id":"https://openalex.org/W2008253137","doi":"https://doi.org/10.1016/j.brainres.2009.09.107","title":"Magnolol and honokiol prevent learning and memory impairment and cholinergic deficit in SAMP8 mice","display_name":"Magnolol and honokiol prevent learning and memory impairment and cholinergic deficit in SAMP8 mice","publication_year":2009,"publication_date":"2009-10-07","ids":{"openalex":"https://openalex.org/W2008253137","doi":"https://doi.org/10.1016/j.brainres.2009.09.107","mag":"2008253137","pmid":"https://pubmed.ncbi.nlm.nih.gov/19815000"},"language":"en","primary_location":{"id":"doi:10.1016/j.brainres.2009.09.107","doi":"https://doi.org/10.1016/j.brainres.2009.09.107","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.brainres.2009.09.107","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037951576","display_name":"Nobuaki Matsui","orcid":"https://orcid.org/0000-0002-4252-2072","observed_orcids":["https://orcid.org/0000-0002-4252-2072"]},"institutions":[{"id":"https://openalex.org/I89098413","display_name":"Tokushima Bunri University","ror":"https://ror.org/00smwky98","country_code":"JP","type":"education","lineage":["https://openalex.org/I89098413"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobuaki Matsui","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan. matsui@ph.bunri-u.ac.jp","Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan. matsui@ph.bunri-u.ac.jp","institution_ids":["https://openalex.org/I89098413"]},{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan","institution_ids":["https://openalex.org/I89098413"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kazuki Takahashi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89098413","display_name":"Tokushima Bunri University","ror":"https://ror.org/00smwky98","country_code":"JP","type":"education","lineage":["https://openalex.org/I89098413"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuki Takahashi","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan","institution_ids":["https://openalex.org/I89098413"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073207827","display_name":"Miho Takeichi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89098413","display_name":"Tokushima Bunri University","ror":"https://ror.org/00smwky98","country_code":"JP","type":"education","lineage":["https://openalex.org/I89098413"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Miho Takeichi","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan","institution_ids":["https://openalex.org/I89098413"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013865410","display_name":"Touma Kuroshita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89098413","display_name":"Tokushima Bunri University","ror":"https://ror.org/00smwky98","country_code":"JP","type":"education","lineage":["https://openalex.org/I89098413"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Touma Kuroshita","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan","institution_ids":["https://openalex.org/I89098413"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kaori Noguchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89098413","display_name":"Tokushima Bunri University","ror":"https://ror.org/00smwky98","country_code":"JP","type":"education","lineage":["https://openalex.org/I89098413"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kaori Noguchi","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan","institution_ids":["https://openalex.org/I89098413"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kana Yamazaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89098413","display_name":"Tokushima Bunri University","ror":"https://ror.org/00smwky98","country_code":"JP","type":"education","lineage":["https://openalex.org/I89098413"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kana Yamazaki","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan","institution_ids":["https://openalex.org/I89098413"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057634492","display_name":"Hideaki Tagashira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89098413","display_name":"Tokushima Bunri University","ror":"https://ror.org/00smwky98","country_code":"JP","type":"education","lineage":["https://openalex.org/I89098413"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hideaki Tagashira","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan","institution_ids":["https://openalex.org/I89098413"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012618855","display_name":"Kenichi Tsutsui","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89098413","display_name":"Tokushima Bunri University","ror":"https://ror.org/00smwky98","country_code":"JP","type":"education","lineage":["https://openalex.org/I89098413"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kenichi Tsutsui","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan","institution_ids":["https://openalex.org/I89098413"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hideki Okada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89098413","display_name":"Tokushima Bunri University","ror":"https://ror.org/00smwky98","country_code":"JP","type":"education","lineage":["https://openalex.org/I89098413"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hideki Okada","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan","institution_ids":["https://openalex.org/I89098413"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031482331","display_name":"Yuki Kido","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89098413","display_name":"Tokushima Bunri University","ror":"https://ror.org/00smwky98","country_code":"JP","type":"education","lineage":["https://openalex.org/I89098413"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuki Kido","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan","institution_ids":["https://openalex.org/I89098413"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yumiko Yasui","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89098413","display_name":"Tokushima Bunri University","ror":"https://ror.org/00smwky98","country_code":"JP","type":"education","lineage":["https://openalex.org/I89098413"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yumiko Yasui","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan","institution_ids":["https://openalex.org/I89098413"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070302842","display_name":"Nobuyuki Fukuishi","orcid":"https://orcid.org/0000-0002-9315-6121","observed_orcids":["https://orcid.org/0000-0002-9315-6121"]},"institutions":[{"id":"https://openalex.org/I89098413","display_name":"Tokushima Bunri University","ror":"https://ror.org/00smwky98","country_code":"JP","type":"education","lineage":["https://openalex.org/I89098413"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobuyuki Fukuishi","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan","institution_ids":["https://openalex.org/I89098413"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062126268","display_name":"Yoshiyasu Fukuyama","orcid":"https://orcid.org/0000-0003-0989-172X","observed_orcids":["https://orcid.org/0000-0003-0989-172X"]},"institutions":[{"id":"https://openalex.org/I89098413","display_name":"Tokushima Bunri University","ror":"https://ror.org/00smwky98","country_code":"JP","type":"education","lineage":["https://openalex.org/I89098413"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshiyasu Fukuyama","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan","institution_ids":["https://openalex.org/I89098413"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108391922","display_name":"Masaaki Akagi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89098413","display_name":"Tokushima Bunri University","ror":"https://ror.org/00smwky98","country_code":"JP","type":"education","lineage":["https://openalex.org/I89098413"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaaki Akagi","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima City, Tokushima 770-8514, Japan","institution_ids":["https://openalex.org/I89098413"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I89098413"],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":4.1696,"has_fulltext":false,"cited_by_count":103,"citation_normalized_percentile":{"value":0.94450025,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"1305","issue":null,"first_page":"108","last_page":"117"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13677","display_name":"Magnolia and Illicium research","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13677","display_name":"Magnolia and Illicium research","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12891","display_name":"Medicinal Plants and Neuroprotection","score":0.007799999788403511,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/magnolol","display_name":"magnolol","score":1.0},{"id":"https://openalex.org/keywords/honokiol","display_name":"honokiol","score":1.0},{"id":"https://openalex.org/keywords/magnolia","display_name":"Magnolia","score":0.8339999914169312},{"id":"https://openalex.org/keywords/samp8-mice","display_name":"SAMP8 mice","score":0.8980000019073486},{"id":"https://openalex.org/keywords/cholinergic-deficit","display_name":"cholinergic deficit","score":0.9679999947547913},{"id":"https://openalex.org/keywords/choline-acetyltransferase","display_name":"choline acetyltransferase","score":0.9150000214576721},{"id":"https://openalex.org/keywords/medial-septum","display_name":"medial septum","score":0.8059999942779541},{"id":"https://openalex.org/keywords/diagonal-band-of-brodmann","display_name":"diagonal band of Brodmann","score":0.9819999933242798},{"id":"https://openalex.org/keywords/akt-phosphorylation","display_name":"Akt phosphorylation","score":0.9599999785423279},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.8989999890327454},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.8320000171661377},{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.7580000162124634},{"id":"https://openalex.org/keywords/neurotrophic-factors","display_name":"neurotrophic factors","score":0.6499999761581421}],"concepts":[{"id":"https://openalex.org/C2781334404","wikidata":"https://www.wikidata.org/wiki/Q5896650","display_name":"Honokiol","level":2,"score":0.9857860803604126},{"id":"https://openalex.org/C2781009524","wikidata":"https://www.wikidata.org/wiki/Q6732002","display_name":"Magnolol","level":2,"score":0.9714755415916443},{"id":"https://openalex.org/C22885893","wikidata":"https://www.wikidata.org/wiki/Q4862743","display_name":"Cholinergic","level":2,"score":0.6339802742004395},{"id":"https://openalex.org/C198399640","wikidata":"https://www.wikidata.org/wiki/Q14863671","display_name":"Choline acetyltransferase","level":3,"score":0.5810976624488831},{"id":"https://openalex.org/C44752575","wikidata":"https://www.wikidata.org/wiki/Q1417562","display_name":"Morris water navigation task","level":3,"score":0.4809240996837616},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.47776567935943604},{"id":"https://openalex.org/C104966671","wikidata":"https://www.wikidata.org/wiki/Q12167532","display_name":"Cholinergic neuron","level":3,"score":0.47140195965766907},{"id":"https://openalex.org/C2780759288","wikidata":"https://www.wikidata.org/wiki/Q1042288","display_name":"Magnolia officinalis","level":4,"score":0.45140326023101807},{"id":"https://openalex.org/C2779715522","wikidata":"https://www.wikidata.org/wiki/Q507027","display_name":"Forebrain","level":3,"score":0.4447680115699768},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4161604642868042},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.40744853019714355},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3973267078399658},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.39707714319229126},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.37709683179855347},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3758785128593445},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.27099335193634033},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.13245952129364014},{"id":"https://openalex.org/C188947578","wikidata":"https://www.wikidata.org/wiki/Q200253","display_name":"Traditional Chinese medicine","level":3,"score":0.06761109828948975},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000109","descriptor_name":"Acetylcholine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001362","descriptor_name":"Avoidance Learning","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001713","descriptor_name":"Biphenyl Compounds","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D002452","descriptor_name":"Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004365","descriptor_name":"Drugs, Chinese Herbal","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010766","descriptor_name":"Phosphorylation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016548","descriptor_name":"Prosencephalon","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016548","descriptor_name":"Prosencephalon","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017705","descriptor_name":"Lignans","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D019001","descriptor_name":"Nitric Oxide Synthase","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D021641","descriptor_name":"Recognition, Psychology","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D051057","descriptor_name":"Proto-Oncogene Proteins c-akt","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.brainres.2009.09.107","doi":"https://doi.org/10.1016/j.brainres.2009.09.107","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.brainres.2009.09.107","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},{"id":"pmid:19815000","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19815000","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320327572","display_name":"Promotion and Mutual Aid Corporation for Private Schools of Japan","ror":"https://ror.org/05h2t6865"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1492009115","https://openalex.org/W1565095682","https://openalex.org/W1609471181","https://openalex.org/W1964524647","https://openalex.org/W1964749256","https://openalex.org/W1966140223","https://openalex.org/W1967455093","https://openalex.org/W1967866688","https://openalex.org/W1969592278","https://openalex.org/W1977647185","https://openalex.org/W1979862274","https://openalex.org/W1982380723","https://openalex.org/W1985468502","https://openalex.org/W1988725623","https://openalex.org/W1994067502","https://openalex.org/W1999511974","https://openalex.org/W1999857170","https://openalex.org/W2004121271","https://openalex.org/W2004729403","https://openalex.org/W2014335950","https://openalex.org/W2015759422","https://openalex.org/W2020215900","https://openalex.org/W2030087128","https://openalex.org/W2030608279","https://openalex.org/W2035953746","https://openalex.org/W2038471328","https://openalex.org/W2038940716","https://openalex.org/W2059664344","https://openalex.org/W2075529771","https://openalex.org/W2091659696","https://openalex.org/W2115881832","https://openalex.org/W2124437258","https://openalex.org/W2132870100","https://openalex.org/W2161483044","https://openalex.org/W2185000518","https://openalex.org/W2323364669"],"related_works":["https://openalex.org/W2069818459","https://openalex.org/W2004121271","https://openalex.org/W2144302234","https://openalex.org/W3145424636","https://openalex.org/W3092778362","https://openalex.org/W2023628610","https://openalex.org/W2067207644","https://openalex.org/W2037194302","https://openalex.org/W1979258651","https://openalex.org/W2021354710"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":15}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}