{"id":"https://openalex.org/W2008200219","doi":"https://doi.org/10.1016/s0003-4975(10)64842-4","title":"The Effect of Extracorporeal Circulation on Serotonin Metabolism","display_name":"The Effect of Extracorporeal Circulation on Serotonin Metabolism","publication_year":1972,"publication_date":"1972-03-01","ids":{"openalex":"https://openalex.org/W2008200219","doi":"https://doi.org/10.1016/s0003-4975(10)64842-4","mag":"2008200219","pmid":"https://pubmed.ncbi.nlm.nih.gov/5019850"},"language":"en","primary_location":{"id":"doi:10.1016/s0003-4975(10)64842-4","doi":"https://doi.org/10.1016/s0003-4975(10)64842-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0003-4975(10)64842-4","pdf_url":"https://doi.org/10.1016/s0003-4975(10)64842-4","source":{"id":"https://openalex.org/S144860794","display_name":"The Annals of Thoracic Surgery","issn_l":"0003-4975","issn":["0003-4975","1552-6259"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of Thoracic Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/s0003-4975(10)64842-4","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005382499","display_name":"G\u00fcrler Ili\u00e7in","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"G\u00fcrler Ili\u00e7in","raw_affiliation_strings":["Departments of Internal Medicine and Adult Thoracic and Cardiovascular Surgery,","Hacettepe University Faculty of Medicine, Ankara, Turkey","Hacettepe University, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Internal Medicine and Adult Thoracic and Cardiovascular Surgery,","institution_ids":[]},{"raw_affiliation_string":"Hacettepe University Faculty of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]},{"raw_affiliation_string":"Hacettepe University, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066769483","display_name":"Argun Saylam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Argun Saylam","raw_affiliation_strings":["Departments of Internal Medicine and Adult Thoracic and Cardiovascular Surgery,","Hacettepe University Faculty of Medicine, Ankara, Turkey","Hacettepe University, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Internal Medicine and Adult Thoracic and Cardiovascular Surgery,","institution_ids":[]},{"raw_affiliation_string":"Hacettepe University Faculty of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]},{"raw_affiliation_string":"Hacettepe University, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042437302","display_name":"Ahmet Bozer","orcid":"https://orcid.org/0000-0002-0467-741X","observed_orcids":["https://orcid.org/0000-0002-0467-741X"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"A. Y\u00fcksel Bozer","raw_affiliation_strings":["Departments of Internal Medicine and Adult Thoracic and Cardiovascular Surgery,","Hacettepe University Faculty of Medicine, Ankara, Turkey","Hacettepe University, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Internal Medicine and Adult Thoracic and Cardiovascular Surgery,","institution_ids":[]},{"raw_affiliation_string":"Hacettepe University Faculty of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]},{"raw_affiliation_string":"Hacettepe University, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I66514158"],"apc_list":{"value":3200,"currency":"USD","value_usd":3200},"apc_paid":null,"fwci":1.2264,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.77088289,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":"3","first_page":"225","last_page":"228"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/extracorporeal-circulation","display_name":"extracorporeal circulation","score":0.8980000019073486},{"id":"https://openalex.org/keywords/serotonin-metabolism","display_name":"serotonin metabolism","score":0.9679999947547913},{"id":"https://openalex.org/keywords/5-hydroxyindoleacetic-acid","display_name":"5-hydroxyindoleacetic acid","score":0.9959999918937683},{"id":"https://openalex.org/keywords/urinary-excretion","display_name":"urinary excretion","score":0.7670000195503235},{"id":"https://openalex.org/keywords/open-heart-surgery","display_name":"open heart surgery","score":0.7990000247955322},{"id":"https://openalex.org/keywords/cardiopulmonary-bypass","display_name":"cardiopulmonary bypass","score":0.8889999985694885}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9248671531677246},{"id":"https://openalex.org/C2994232697","wikidata":"https://www.wikidata.org/wiki/Q1115882","display_name":"Extracorporeal circulation","level":2,"score":0.7791334986686707},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.6863084435462952},{"id":"https://openalex.org/C11111821","wikidata":"https://www.wikidata.org/wiki/Q205880","display_name":"Circulation (fluid dynamics)","level":2,"score":0.4575674831867218},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.4236862063407898},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31483012437820435},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.07298076152801514},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D005112","descriptor_name":"Extracorporeal Circulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006348","descriptor_name":"Cardiac Surgical Procedures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006897","descriptor_name":"Hydroxyindoleacetic Acid","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0003-4975(10)64842-4","doi":"https://doi.org/10.1016/s0003-4975(10)64842-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0003-4975(10)64842-4","pdf_url":"https://doi.org/10.1016/s0003-4975(10)64842-4","source":{"id":"https://openalex.org/S144860794","display_name":"The Annals of Thoracic Surgery","issn_l":"0003-4975","issn":["0003-4975","1552-6259"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of Thoracic Surgery","raw_type":"journal-article"},{"id":"pmid:5019850","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5019850","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of thoracic surgery","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/s0003-4975(10)64842-4","doi":"https://doi.org/10.1016/s0003-4975(10)64842-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0003-4975(10)64842-4","pdf_url":"https://doi.org/10.1016/s0003-4975(10)64842-4","source":{"id":"https://openalex.org/S144860794","display_name":"The Annals of Thoracic Surgery","issn_l":"0003-4975","issn":["0003-4975","1552-6259"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of Thoracic Surgery","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":true},"content_urls":{"grobid_xml":"https://content.openalex.org/works/W2008200219.grobid-xml"},"referenced_works_count":14,"referenced_works":["https://openalex.org/W1560688302","https://openalex.org/W1964493992","https://openalex.org/W1980785206","https://openalex.org/W2009436680","https://openalex.org/W2016273730","https://openalex.org/W2045384699","https://openalex.org/W2070464979","https://openalex.org/W2131927982","https://openalex.org/W2144888644","https://openalex.org/W2331596982","https://openalex.org/W2400903103","https://openalex.org/W2410737173","https://openalex.org/W2414495423","https://openalex.org/W2435754206"],"related_works":["https://openalex.org/W2441017235","https://openalex.org/W2408282823","https://openalex.org/W2419786838","https://openalex.org/W2412780686","https://openalex.org/W2334057046","https://openalex.org/W2466030755","https://openalex.org/W2416426732","https://openalex.org/W2411801359","https://openalex.org/W2413258234","https://openalex.org/W2414697103"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}